fangchinoline has been researched along with tetrandrine in 46 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (2.17) | 18.7374 |
| 1990's | 7 (15.22) | 18.2507 |
| 2000's | 18 (39.13) | 29.6817 |
| 2010's | 13 (28.26) | 24.3611 |
| 2020's | 7 (15.22) | 2.80 |
| Authors | Studies |
|---|---|
| Angerhofer, CK; Cordell, GA; Johnson, ME; Lin, LZ; Pezzuto, JM; Ruangrungsi, N; Shieh, HL; Xue, L | 1 |
| Angerhofer, CK; Cordell, GA; Guinaudeau, H; Pezzuto, JM; Wongpanich, V | 1 |
| Dong, SS; Liu, C; Yang, YF; Zhao, SX | 1 |
| Kobayashi, Y; Nakamura, K; Onai, N; Suda, M; Sugimoto, Y; Tsunokawa, Y; Watanabe, N | 1 |
| Ahn, HY; Kim, HS; Oh, KW; Zhang, YH | 1 |
| Choi, EJ; Choi, SU; Jung, NP; Kim, HS; Kim, KH; Kim, S; Lee, CO; Park, SH; Park, WK; Zhang, YH | 1 |
| Kim, HS; Yun, YP; Zhang, YH | 1 |
| Fang, LH; Kim, HS; Lee, HK; Yun, YP; Zhang, YH | 1 |
| Chang, YK; Choi, HS; Chung, MW; Kim, HS; Kim, Y; Lim, HK; Min, KR | 1 |
| Chen, CF; Pang, KT; Shan, J; Wong, TM; Wu, S; Yu, XC | 1 |
| Chen, CF; Pang, KT; Shan, J; Wang, GY; Wong, TM; Wu, S; Yu, XC | 1 |
| Li, HY; Wong, TM; Wu, S; Yu, XC | 1 |
| Chen, CF; Chiou, WF; Chou, CJ; Shen, YC | 1 |
| Kobayashi, S; Kontani, H; Liu, YY; Tsutsumi, T | 1 |
| Ban, JY; Koh, SB; Lee, BY; Seong, YH | 1 |
| He, FY; Liu, RM; Sun, AL | 1 |
| Hikiami, H; Kouta, K; Sakakibara, I; Sekiya, N; Shimada, Y; Terasawa, K; Yokoyama, K | 1 |
| Chen, A; Chen, X; Chen, Y; Gao, W; Hu, Z; Li, Y; Lin, S | 1 |
| Chan, E; Koh, HL; Wang, H; Woo, SO; Zhou, S | 1 |
| Chen, X; Hu, Z; Liu, L | 1 |
| Chen, X; Hu, Z; Liu, L; Liu, X | 1 |
| Du, G; Li, Z; Ni, K | 1 |
| Guo, L; Liu, M; Liu, X; Yang, C; Zhang, H | 1 |
| Cao, ML; Chen, XG; Jia, BX; Li, K; Li, YQ; Liu, CH; Qi, YX | 1 |
| Duan, W; Fu, M; Geng, Y; Wang, D; Wang, X; Zhang, L | 1 |
| Chen, X; Deng, X; Liu, L | 1 |
| Cai, M; Du, G; Fan, X; Li, Z; Qiang, G; Yang, Z; Ying, J | 1 |
| Chen, J; Ji, X; Peng, A; Sun, H; Tang, Y; Xiang, J; Zhao, C; Zhou, H | 1 |
| Chen, Z; Li, S; Liu, L | 1 |
| Chen, DL; Chen, QH; He, P; Jian, XX; Liu, GT; Sun, H; Wang, FP | 1 |
| Liu, R; Sun, A; Tang, Y; Zhang, Y | 1 |
| Cai, B; Cai, H; Cao, G; Liu, X; Pei, K; Shi, F; Wang, X; Xu, X | 1 |
| Cai, B; Liu, X; Qin, K; Shi, F; Wang, X; Xu, X; Zhu, T | 1 |
| Fu, F; Lu, X; Nian, H; Shen, J; Wu, T; Zhang, R | 1 |
| Jiao, B; Li, D; Liu, C; Liu, H; Liu, Y; Zhang, Q; Zhao, S | 1 |
| Bao, L; He, Z; Jiao, Y; Li, H; Liu, J; Lu, H; Pan, W; Yang, S; Zhang, W | 1 |
| Jang, MS; Jin, YH; Kim, DE; Kim, HR; Kim, S; Kwon, S; Lee, JY; Min, JS; Shin, YS; Song, JH | 1 |
| Dong, TTX; Duan, R; Guo, SC; Kong, XP; Leung, KW; Liu, EYL; Ren, HQ; Tsim, KWK | 1 |
| Chan, EWC; Chan, HT; Wong, SK | 1 |
| Chen, JS; Gao, XZ; Liu, C; Liu, YF; Luo, Y; Lv, XT; Sun, B; Sun, JY; Wang, MX; Zhang, RR; Zhang, YK | 1 |
| Chang, S; Feng, B; Guan, J; Ji, Y; Sang, Y; Wang, L; Zhang, T; Zhu, H | 1 |
| Cardellina Ii, JH; Currens, MJ; Klausmeyer, P; McCloud, TG; Scudiero, DA; Shoemaker, RH | 1 |
| Gatadi, S; Gour, J; Nanduri, S | 1 |
| Ben-David, Y; Chen, C; Fan, Y; Hu, S; Pan, W; Song, J; Wang, C; Yang, J | 1 |
| Chen, S; Hirano, T; Wang, X; Wu, H; Xu, W; Yamada, H | 1 |
| Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M | 1 |
3 review(s) available for fangchinoline and tetrandrine
| Article | Year |
|---|---|
Cardiovascular actions of Radix Stephaniae Tetrandrae: a comparison with its main component, tetrandrine.
Topics: Alkaloids; Animals; Anti-Arrhythmia Agents; Antihypertensive Agents; Benzylisoquinolines; Calcium Channel Blockers; Coronary Circulation; Drugs, Chinese Herbal; Heart Rate; Magnoliopsida; Plant Roots; Plants, Medicinal | 2000 |
An overview on the chemistry, pharmacology and anticancer properties of tetrandrine and fangchinoline (alkaloids) from Stephania tetrandra roots.
Topics: Alkaloids; Benzylisoquinolines; Stephania tetrandra | 2021 |
Natural product derived promising anti-MRSA drug leads: A review.
Topics: Animals; Anti-Bacterial Agents; Biological Products; Dose-Response Relationship, Drug; Humans; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship | 2019 |
43 other study(ies) available for fangchinoline and tetrandrine
| Article | Year |
|---|---|
Cytotoxic and antimalarial bisbenzylisoquinoline alkaloids from Cyclea barbata.
Topics: Alkaloids; Animals; Antimalarials; Antineoplastic Agents, Phytogenic; Asia; Benzylisoquinolines; Cell Survival; Drug Screening Assays, Antitumor; Erythrocytes; Humans; In Vitro Techniques; KB Cells; Leukemia P388; Magnetic Resonance Spectroscopy; Plants, Medicinal; Plasmodium falciparum; Spectrophotometry, Ultraviolet; Tumor Cells, Cultured | 1993 |
Antiplasmodial and cytotoxic activity of natural bisbenzylisoquinoline alkaloids.
Topics: Alkaloids; Animals; Antimalarials; Antineoplastic Agents, Phytogenic; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Plasmodium falciparum; Structure-Activity Relationship; Tumor Cells, Cultured | 1999 |
[Dual-wavelength TLC densitometric determination of alkaloids in radix Stephaniae tetrandrae].
Topics: Alkaloids; Benzylisoquinolines; Berberine; Berberine Alkaloids; Chromatography, Thin Layer; Densitometry; Drugs, Chinese Herbal | 1988 |
Inhibitory effects of bisbenzylisoquinoline alkaloids on induction of proinflammatory cytokines, interleukin-1 and tumor necrosis factor-alpha.
Topics: Alkaloids; Anti-Inflammatory Agents, Non-Steroidal; Base Sequence; Benzylisoquinolines; DNA Primers; Drugs, Chinese Herbal; Humans; Interleukin-1; Molecular Sequence Data; Monocytes; Neutralization Tests; RNA, Messenger; Tumor Necrosis Factor-alpha | 1995 |
Vasodilating and hypotensive effects of fangchinoline and tetrandrine on the rat aorta and the stroke-prone spontaneously hypertensive rat.
Topics: Alkaloids; Animals; Aorta; Benzylisoquinolines; Blood Pressure; Calcium Channel Blockers; Drugs, Chinese Herbal; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Potassium; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley | 1997 |
The bisbenzylisoquinoline alkaloids, tetrandine and fangchinoline, enhance the cytotoxicity of multidrug resistance-related drugs via modulation of P-glycoprotein.
Topics: Alkaloids; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzylisoquinolines; Cell Survival; Colorectal Neoplasms; Dactinomycin; Drug Resistance, Multiple; Drug Screening Assays, Antitumor; Drugs, Chinese Herbal; Female; Humans; Isoquinolines; Molecular Structure; Ovarian Neoplasms; Verapamil | 1998 |
Effects of tetrandrine and fangchinoline on experimental thrombosis in mice and human platelet aggregation.
Topics: Alkaloids; Animals; Benzylisoquinolines; Humans; Male; Mice; Mice, Inbred ICR; Platelet Aggregation Inhibitors; Thrombosis | 1999 |
Effects of tetrandrine and fangchinoline on human platelet aggregation and thromboxane B2 formation.
Topics: Alkaloids; Benzylisoquinolines; Blood Platelets; Drugs, Chinese Herbal; Humans; In Vitro Techniques; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thromboxane B2 | 1999 |
Anti-inflammatory effects of fangchinoline and tetrandrine.
Topics: Alkaloids; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzylisoquinolines; Cells, Cultured; Croton Oil; Dexamethasone; Ear; Edema; Humans; In Vitro Techniques; Indomethacin; Interleukin-5; Interleukin-6; Korea; Male; Medicine, Traditional; Mice; Mice, Inbred ICR; Prostaglandin-Endoperoxide Synthases; Structure-Activity Relationship | 2000 |
Cardiac effects of the extract and active components of Radix stephaniae tetrandrae. I. Electrically-induced intracellular calcium transient and protein release during the calcium paradox.
Topics: Alkaloids; Animals; Benzylisoquinolines; Calcium; Calcium Channel Blockers; Dose-Response Relationship, Drug; Drug Interactions; Drugs, Chinese Herbal; Electric Stimulation; Heart Ventricles; In Vitro Techniques; Male; Myocardium; Proteins; Rats; Rats, Sprague-Dawley | 2001 |
Cardiac effects of the extract and active components of radix stephaniae tetrandrae. II. Myocardial infarct, arrhythmias, coronary arterial flow and heart rate in the isolated perfused rat heart.
Topics: Alkaloids; Animals; Arrhythmias, Cardiac; Benzylisoquinolines; Calcium Channel Blockers; Coronary Circulation; Dose-Response Relationship, Drug; Drug Interactions; Drugs, Chinese Herbal; Heart; Heart Rate; In Vitro Techniques; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Perfusion; Rats; Rats, Sprague-Dawley; Verapamil | 2001 |
Anti-inflammatory effects of the partially purified extract of radix Stephaniae tetrandrae: comparative studies of its active principles tetrandrine and fangchinoline on human polymorphonuclear leukocyte functions.
Topics: Alkaloids; Anti-Inflammatory Agents; Benzylisoquinolines; Biological Transport; Calcium; Cell Adhesion; Cell Movement; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Macrophage-1 Antigen; Magnoliopsida; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Plant Extracts; Reactive Oxygen Species; Up-Regulation | 2001 |
Anti-hyperglycemic effect of fangchinoline isolated from Stephania tetrandra Radix in streptozotocin-diabetic mice.
Topics: Alkaloids; Animals; Benzylisoquinolines; Blood Glucose; Diabetes Mellitus, Experimental; Disease Models, Animal; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Fasting; Hyperglycemia; Insulin; Male; Mice; Mice, Inbred Strains; Stephania tetrandra; Structure-Activity Relationship | 2003 |
Protective effects of fangchinoline and tetrandrine on hydrogen peroxide-induced oxidative neuronal cell damage in cultured rat cerebellar granule cells.
Topics: Alkaloids; Animals; Benzylisoquinolines; Calcium; Cell Death; Cerebellum; Cytoplasmic Granules; Female; Hydrogen Peroxide; N-Methylaspartate; Neurons; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Phytotherapy; Plant Roots; Pregnancy; Rats; Rats, Sprague-Dawley; Stephania tetrandra; Verapamil | 2003 |
[Separation and identification of alkaloids in Stephania tetrandra by capillary electrophoresis electrospray-MS/MS].
Topics: Alkaloids; Benzylisoquinolines; Electrophoresis, Capillary; Plants, Medicinal; Spectrometry, Mass, Electrospray Ionization; Stephania tetrandra | 2004 |
Inhibitory effects of Stephania tetrandra S. Moore on free radical-induced lysis of rat red blood cells.
Topics: Alkaloids; Animals; Antioxidants; Benzylisoquinolines; Berberine; Dose-Response Relationship, Drug; Free Radical Scavengers; Free Radicals; Hemolysis; In Vitro Techniques; Male; Molecular Structure; Plant Extracts; Rats; Rats, Wistar; Stephania tetrandra; Time Factors | 2005 |
Nonaqueous capillary electrophoresis for rapid and sensitive determination of fangchinoline and tetrandrine in radix Stephaniae tetrandrae and its medicinal preparations.
Topics: Alkaloids; Benzylisoquinolines; Drugs, Chinese Herbal; Electrophoresis, Capillary; Humans; Molecular Structure; Plants, Medicinal; Sensitivity and Specificity; Solvents; Stephania tetrandra | 2005 |
Detection of aristolochic acid I, tetrandrine and fangchinoline in medicinal plants by high performance liquid chromatography and liquid chromatography/mass spectrometry.
Topics: Alkaloids; Aristolochia; Aristolochic Acids; Benzylisoquinolines; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Indicators and Reagents; Mass Spectrometry; Plant Extracts; Plant Roots; Plants, Medicinal; Reference Standards; Stephania | 2006 |
Online concentration by field-amplified sample injection in acidic buffer for analysis of fangchinoline and tetrandrine in herbal medicine by flow injection-micellar electrokinetic capillary chromatography.
Topics: Alkaloids; Benzylisoquinolines; Buffers; Chromatography, Micellar Electrokinetic Capillary; Flow Injection Analysis; Phase Transition; Sensitivity and Specificity | 2005 |
Separation and determination of tetrandrine and fangchinoline in herbal medicines by flow injection-micellar electrokinetic capillary chromatography with internal standard method.
Topics: Alkaloids; Benzylisoquinolines; Chromatography, Micellar Electrokinetic Capillary; Electrolytes; Herbal Medicine; Hydrogen-Ion Concentration; Methanol; Reproducibility of Results; Sensitivity and Specificity; Time Factors | 2005 |
[Simultaneous analysis of six effective components in the anti-Alzheimer's disease effective component group of Xiao-Xu-Ming Decoction].
Topics: Alzheimer Disease; Animals; Benzoates; Benzylisoquinolines; Bridged-Ring Compounds; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Flavonoids; Glucosides; Monosaccharides; Monoterpenes; Xanthenes | 2007 |
Determination of tetrandrine and fangchinoline in plasma samples using hollow fiber liquid-phase microextraction combined with high-performance liquid chromatography.
Topics: Alkaloids; Benzylisoquinolines; Chemical Fractionation; Chromatography, High Pressure Liquid; Humans; Molecular Structure; Reproducibility of Results | 2007 |
[Determination of tetrandrine and fangchinoline in Radix Stephaniae tetrandrae and its preparation by nonaqueous capillary chromatography].
Topics: Benzylisoquinolines; Calibration; Capillary Electrochromatography; Capsules; Drugs, Chinese Herbal; Plant Roots; Plants, Medicinal; Quality Control; Reproducibility of Results; Stephania tetrandra | 2007 |
Ionic liquid-based ultrasound-assisted extraction of fangchinoline and tetrandrine from Stephaniae tetrandrae.
Topics: Benzylisoquinolines; Drugs, Chinese Herbal; Ionic Liquids; Molecular Structure; Stephania tetrandra; Ultrasonics | 2009 |
Micelle to trapping solution stacking in micellar electrokinetic chromatography.
Topics: Benzylisoquinolines; Chromatography, Micellar Electrokinetic Capillary; Micelles; Plant Extracts; Stephania tetrandra | 2010 |
[Pharmacokinetics of fangchinoline and tetrandrine in rats].
Topics: Animals; Benzylisoquinolines; Drugs, Chinese Herbal; Rats; Rats, Wistar | 2009 |
The interaction of telomere DNA G-quadruplex with three bis-benzyltetrahydroisoquinoline alkaloids.
Topics: Alkaloids; Benzylisoquinolines; Cell Cycle Checkpoints; Cell Survival; Cells, Cultured; Epithelial Cells; G-Quadruplexes; Humans; Molecular Structure; Telomere | 2011 |
Simultaneous determination of tetrandrine and fangchinoline in herbal medicine Stephania tetrandra S. Moore by liquid chromatography with electrochemical detection.
Topics: Benzylisoquinolines; Chromatography, High Pressure Liquid; Electrochemical Techniques; Plant Extracts; Plant Preparations; Plants, Medicinal; Stephania tetrandra | 2012 |
Partial synthesis and biological evaluation of bisbenzylisoquinoline alkaloids derivatives: potential modulators of multidrug resistance in cancer.
Topics: Alkaloids; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzylisoquinolines; Doxorubicin; Drug Resistance, Multiple; Humans; Molecular Structure; Rhodamine 123 | 2012 |
Simultaneous determination of fangchinoline and tetrandrine in Stephania tetrandra S. Moore by using 1-alkyl-3-methylimidazolium-based ionic liquids as the RP-HPLC mobile phase additives.
Topics: Benzylisoquinolines; Borates; Chromatography, High Pressure Liquid; Hydrogen-Ion Concentration; Imidazoles; Ionic Liquids; Medicine, Chinese Traditional; Molecular Structure; Stephania tetrandra | 2013 |
Ultra high performance liquid chromatography with tandem mass spectrometry method for the determination of tetrandrine and fangchinoline in rat plasma after oral administration of Fangji Huangqi Tang and Stephania tetrandra S. Moore extracts.
Topics: Acetonitriles; Administration, Oral; Animals; Area Under Curve; Benzylisoquinolines; Calibration; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Limit of Detection; Male; Plant Extracts; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tandem Mass Spectrometry | 2015 |
Screening and identification of multiple constituents and their metabolites of Fangji Huangqi Tang in rats by ultra-high performance liquid chromatography coupled with quadrupole time-of-flight tandem mass spectrometry basing on coupling data processing t
Topics: Animals; Benzylisoquinolines; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Male; Rats; Rats, Sprague-Dawley; Tandem Mass Spectrometry | 2015 |
Simultaneous Determination of Fangchinoline and Tetrandrine in Qi-Fang-Xi-Bi-Granules by RP-HPLC.
Topics: Benzylisoquinolines; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Drugs, Chinese Herbal; Linear Models; Reproducibility of Results; Sensitivity and Specificity | 2015 |
Design, synthesis and biological activities of tetrandrine and fangchinoline derivatives as antitumer agents.
Topics: Antineoplastic Agents; Apoptosis; Benzylisoquinolines; Cell Proliferation; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Hep G2 Cells; Humans; MCF-7 Cells; Molecular Structure; Structure-Activity Relationship | 2017 |
Screening antiproliferative drug for breast cancer from bisbenzylisoquinoline alkaloid tetrandrine and fangchinoline derivatives by targeting BLM helicase.
Topics: Antineoplastic Agents, Phytogenic; Benzylisoquinolines; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; DNA; DNA Helicases; DNA-Binding Proteins; Drosophila Proteins; Drug Screening Assays, Antitumor; Escherichia coli; Female; Human Umbilical Vein Endothelial Cells; Humans; Inhibitory Concentration 50; Protein Binding; RecQ Helicases; Signal Transduction | 2019 |
Natural Bis-Benzylisoquinoline Alkaloids-Tetrandrine, Fangchinoline, and Cepharanthine, Inhibit Human Coronavirus OC43 Infection of MRC-5 Human Lung Cells.
Topics: Antiviral Agents; Benzylisoquinolines; Cell Line; Coronavirus Infections; Coronavirus OC43, Human; Cytokines; Humans; Plant Extracts; Stephania tetrandra | 2019 |
The Cholinesterase Inhibitory Properties of Stephaniae Tetrandrae Radix.
Topics: Acetylcholinesterase; Alkaloids; Benzylisoquinolines; Berberine; Binding Sites; Butyrylcholinesterase; China; Cholinesterase Inhibitors; Donepezil; Drug Combinations; Drug Synergism; GPI-Linked Proteins; Humans; Molecular Docking Simulation; Neuroprotective Agents; Plant Extracts; Plants, Medicinal; Protein Binding; Protein Conformation; Protein Interaction Domains and Motifs; Sesquiterpenes; Solvents; Stephania tetrandra | 2020 |
Design, synthesis and in vitro anticancer research of novel tetrandrine and fangchinoline derivatives.
Topics: Antineoplastic Agents; Apoptosis; Benzylisoquinolines; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Design; Humans; Molecular Structure | 2021 |
UHPLC-MS/MS Method for Quantifying Fangchinoline, Tetrandrine and Calycosin-7-O-β-D-Glucoside of Fangji Huangqi Decoction in Rat Plasma and Its Application to a Pharmacokinetic Study.
Topics: Acetonitriles; Administration, Oral; Animals; Benzylisoquinolines; Chromatography, High Pressure Liquid; Diphenhydramine; Drugs, Chinese Herbal; Glucosides; Isoflavones; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tandem Mass Spectrometry | 2022 |
Discovery and preliminary SAR of bisbenzylisoquinoline alkaloids as inducers of C/EBPα.
Topics: Antineoplastic Agents; Benzylisoquinolines; CCAAT-Enhancer-Binding Protein-alpha; Cell Proliferation; Dose-Response Relationship, Drug; Drug Discovery; Drug Screening Assays, Antitumor; Fruit; Hernandiaceae; High-Throughput Screening Assays; Humans; Molecular Structure; Plant Extracts; Stereoisomerism; Structure-Activity Relationship; U937 Cells | 2012 |
Fangchinoline derivatives induce cell cycle arrest and apoptosis in human leukemia cell lines via suppression of the PI3K/AKT and MAPK signaling pathway.
Topics: Antineoplastic Agents; Apoptosis; Benzylisoquinolines; Cell Cycle Checkpoints; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; MAP Kinase Signaling System; Molecular Structure; Phosphatidylinositol 3-Kinases; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Structure-Activity Relationship; Tumor Cells, Cultured | 2020 |
Bisbenzylisoquinoline alkaloids and P-glycoprotein function: A structure activity relationship study.
Topics: Alkaloids; ATP Binding Cassette Transporter, Subfamily B; Benzylisoquinolines; Cell Line, Tumor; Drug Resistance, Neoplasm; Humans; Molecular Conformation; Structure-Activity Relationship | 2020 |
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries | 2023 |