famotidine and piperidines

famotidine has been researched along with piperidines in 64 studies

Research

Studies (64)

TimeframeStudies, this research(%)All Research%
pre-19904 (6.25)18.7374
1990's29 (45.31)18.2507
2000's20 (31.25)29.6817
2010's11 (17.19)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Audibert, G; Bigard, O; Haberer, JP; Hartemann, D; Saunier, C1
Aihara, H; Hirose-Kijima, H; Muramatsu, M; Otomo, S1
Aihara, H; Isobe, Y; Muramatsu, M; Otomo, S1
Igata, H; Nishida, T; Okabe, S; Takagi, K1
Aihara, H; Isobe, Y; Muramatsu, M; Nagai, H; Otomo, S1
Chida, Y; Nishikawa, M; Ohnishi, H; Sekine, A; Shibata, M; Yamaura, T1
Horikoshi, T; Kobayashi, S; Kusano, M; Matsuzaki, T; Nishioka, T; Ohwada, T; Sekiguchi, T; Sugiyama, M; Toki, M1
Fukui, H; Inagaki, N; Kanamura, A; Kondou, H; Koyama, Y; Wada, H1
Walt, RP1
Emami, S; Fagot, D; Gespach, C1
Aono, M; Mizuta, K; Moriga, M; Narusawa, H1
Brockmeier, D; Lameire, N; Rosenkranz, B1
Ikarashi, Y; Misaki, N; Ohba, S; Ohbayashi, S; Uchida, M1
Bertaccini, G; Grandi, D; Morini, G1
Kagoshima, M; Kodaira, H; Shimada, H1
Chijiiwa, Y; Maruoka, A; Nawata, H; Tanaka, M1
Aoki, T; Fukuda, S; Hanyu, N; Hashimoto, Y; Iikura, M; Ohira, Y1
Hamada, K; Kobayashi, F; Sekiguchi, H; Taga, F; Uchida, H1
Aijima, H; Hamada, K; Nishino, K; Sekiguchi, H; Taga, F; Uchida, H1
Chida, Y; Inaba, N; Ohnishi, H; Onodera, S; Shibata, M; Yamaura, T1
Ikarashi, Y; Kawano, O; Misaki, N; Ohba, S; Uchida, M1
Dallera, F; Gendarini, A; Scanzi, G1
Csepregi, A; Nemesánszky, E1
Hagishita, S; Ishihara, S; Ishihara, Y; Ishikawa, M; Kawanishi, Y; Takahashi, K; Tsushima, T1
Inaba, N; Onodera, S; Shibata, M; Suzuki, T; Tanaka, M; Yamaura, T1
Berstad, A; Hatlebakk, JG1
Bast, A; Bruinier, B; Hol, BE; Jansen, HM; Krouwels, FH; Lutter, R; Out, TA1
Aoyama, M; Arai, Y; Ohnishi, H; Onodera, S; Shibata, M; Tanaka, M; Yamaura, T1
Higuchi, S; Isobe, Y; Kijima, H; Kiuchi, Y; Saitoh, T1
Bertaccini, G; Coppelli, G; Coruzzi, G; Poli, E; Pozzoli, C1
Higuchi, S; Isobe, Y; Kaku, S; Kiuchi, Y; Muramatsu, M; Tanaka, M1
Aoyama, M; Arai, Y; Inaba, N; Nishizawa, A; Onodera, S; Sekine, Y; Shibata, M; Suzuki, T; Tanaka, M1
Ayukawa, O; Kariyazono, H; Moriyama, Y; Nakamura, K; Shinkawa, T; Taira, A; Toyohira, H; Yamada, K; Yamaguchi, T; Yamashita, T; Yotsumoto, G1
Asano, T; Fukushima, Y; Kajiwara, T; Katsube, T; Mori, H; Ogawa, K; Ohkawa, SI; Otsuka, H; Saitoh, T; Takahashi, H; Tamai, M1
Ajioka, H; Matsuura, N; Miyake, H1
Attarzadeh, M; Farzin, D1
Horie, S; Murayama, T; Tsuchiya, S; Uchida, M; Watanabe, K; Yamamoto, H1
Anai, M; Asano, T; Fukushima, Y; Ishikawa, M; Ishikawa, T; Kajiwara, T; Katsube, T; Ogawa, K; Ohkawa, S; Omata, M; Otsuka, H; Saitoh, T1
Anai, M; Asano, T; Fukushima, Y; Ishikawa, M; Ishikawa, T; Kajiwara, T; Katsube, T; Mori, H; Ogawa, K; Ohkawa, S; Omata, M; Otsuka, H; Saitoh, T; Takahashi, H; Tamai, M1
Adachi, K; Fujishiro, H; Kinoshita, Y; Komazawa, Y; Mihara, T1
Ishihara, S; Kawashima, K; Kazumori, H; Kinoshita, Y; Ortega-Cava, CF; Rumi, MA; Sato, H; Yuki, M1
Belai, A; Horie, S; Michael, GJ; Murayama, T; Priestley, JV; Uchida, M; Watanabe, K; Yamamoto, H1
Adachi, K; Azumi, T; Fujisawa, T; Furuta, K; Katsube, T; Kazumori, H; Kinoshita, Y; Komazawa, Y; Mihara, T1
Hashimoto, H; Hirota, K; Kudo, M; Kushikata, T1
Eckman, JR; Wagner, MC; Wick, TM1
Ikawa, K; Inoue, M; Kuroiwa, T; Morikawa, N; Nakamura, M; Shimatani, T; Tazuma, S; Xu, J1
Aoyama, N; Fukuda, M; Kachi, M; Kasuga, M; Miki, I; Morita, Y; Shirasaka, D; Tamura, T1
Arakawa, T; Chono, S; Fujiwara, Y; Higuchi, K; Kitada, K; Nakagawa, K; Oshitani, N; Satoh, H; Shiba, M; Tominaga, K; Uno, H; Watanabe, T1
Harada, N; Okajima, K1
Hayato, S; Ikawa, K; Morikawa, N; Shimatani, T; Tazuma, S1
Abe, Y; Iijima, K; Imatani, A; Inomata, Y; Kawamura, M; Koike, T; Ohara, S; Sehine, H; Shimosegawa, T1
De Ponti, F; Moretti, U; Poluzzi, E; Raschi, E1
Chen, Y; Sun, X; Tian, Y; Zhang, Z1
Haruma, K; Kinoshita, Y; Kusano, M; Ohara, S2
Amagase, K; Kato, S; Ochi, A; Sugihara, T; Takeuchi, K1
Higuchi, K; Murano, M; Tokioka, S; Umegaki, E; Yoda, Y1
Agrawal, SS; Jose, MA1
Aogi, K; Ishiguro, H; Iwata, H; Kawaguchi, K; Kuroi, K; Masuda, N; Morita, S; Nakamura, S; Ohno, S; Toi, M1
Ichikawa, T; Ishihara, K; Iwai, T; Kida, M; Koizumi, W; Shikama, N; Yamamoto, H1
Kraus, MM; Philippu, A; Prast, H1
Chang, YW; Choi, MG; Chun, HJ; Han, SW; Jeong, HY; Jung, HC; Jung, HY; Jung, JT; Kim, EH; Kim, HS; Kim, HY; Kim, JG; Lee, DH; Lee, OJ; Lee, ST; Lee, SW; Lee, YC; Park, JJ; Park, SH; Seol, SY; Youn, SJ1
Aghelkohan, P; Baghbanzadeh, A; Hassanpour, S; Zendehdel, M1
Amagase, K; Higuchi, K; Kato, S; Matsumoto, K; Sano, T; Takeuchi, T; Tominaga, M; Utsumi, D1

Reviews

4 review(s) available for famotidine and piperidines

ArticleYear
Clinical importance of the new H2-antagonists.
    Methods and findings in experimental and clinical pharmacology, 1989, Volume: 11 Suppl 1

    Topics: Animals; Famotidine; Histamine H2 Antagonists; Humans; Nizatidine; Peptic Ulcer; Piperidines; Thiazoles

1989
Pharmacokinetics of histamine (H2)-receptor antagonists, including roxatidine, in chronic renal failure.
    Scandinavian journal of gastroenterology. Supplement, 1988, Volume: 146

    Topics: Anti-Ulcer Agents; Cimetidine; Famotidine; Histamine H2 Antagonists; Humans; Kidney Failure, Chronic; Piperidines; Ranitidine; Renal Dialysis; Thiazoles

1988
[H2-receptor antagonists and alcohol: clinical significance].
    Orvosi hetilap, 1996, Jun-16, Volume: 137, Issue:24

    Topics: Cimetidine; Clinical Medicine; Drug Interactions; Ethanol; Famotidine; Gastric Mucosa; Histamine H2 Antagonists; Humans; Liver; Nizatidine; Piperidines; Ranitidine

1996
Pharmacokinetic optimisation in the treatment of gastro-oesophageal reflux disease.
    Clinical pharmacokinetics, 1996, Volume: 31, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Antacids; Benzimidazoles; Cimetidine; Cisapride; Domperidone; Famotidine; Gastroesophageal Reflux; Histamine H2 Antagonists; Humans; Lansoprazole; Metoclopramide; Nizatidine; Omeprazole; Pantoprazole; Piperidines; Proton Pump Inhibitors; Ranitidine; Sucralfate; Sulfoxides

1996

Trials

9 trial(s) available for famotidine and piperidines

ArticleYear
Influence of lansoprazole, famotidine, roxatidine and rebamipide administration on the urea breath test for the diagnosis of Helicobacter pylori infection.
    Journal of gastroenterology and hepatology, 2003, Volume: 18, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Alanine; Anti-Ulcer Agents; Breath Tests; False Negative Reactions; Famotidine; Female; Helicobacter Infections; Helicobacter pylori; Humans; Lansoprazole; Male; Omeprazole; Piperidines; Predictive Value of Tests; Quinolones; Urea

2003
Helicobacter pylori infection prevents the occurrence of the tolerance phenomenon of histamine H2 receptor antagonists.
    Alimentary pharmacology & therapeutics, 2004, Sep-01, Volume: 20, Issue:5

    Topics: Acetamides; Adult; Ambulatory Care; Circadian Rhythm; Cross-Over Studies; Cross-Sectional Studies; Drug Tolerance; Famotidine; Helicobacter Infections; Helicobacter pylori; Histamine H2 Antagonists; Humans; Hydrogen-Ion Concentration; Male; Middle Aged; Piperidines; Pyridines

2004
Lafutidine, a newly developed antiulcer drug, elevates postprandial intragastric pH and increases plasma calcitonin gene-related peptide and somatostatin concentrations in humans: comparisons with famotidine.
    Digestive diseases and sciences, 2006, Volume: 51, Issue:1

    Topics: Acetamides; Administration, Oral; Adult; Biomarkers; Calcitonin Gene-Related Peptide; Cross-Over Studies; Famotidine; Follow-Up Studies; Gastric Acid; Gastric Acidity Determination; Gastric Mucosa; Histamine H2 Antagonists; Humans; Hydrogen-Ion Concentration; Immunoenzyme Techniques; Male; Piperidines; Postprandial Period; Prospective Studies; Pyridines; Reference Values; Somatostatin; Stomach

2006
No significant difference in neutrophil activation found among three H2RAs.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2007, Volume: 39, Issue:2

    Topics: Acetamides; Adult; Dyspepsia; Famotidine; Female; Helicobacter Infections; Helicobacter pylori; Histamine H2 Antagonists; Humans; Interleukin-8; Male; Middle Aged; Neutrophil Activation; Peroxidase; Piperidines; Pyridines; Ranitidine

2007
Lafutidine can improve the quality of gastric ulcer healing in humans: a randomized, controlled, multicenter trial.
    Inflammopharmacology, 2006, Volume: 14, Issue:5-6

    Topics: Acetamides; Adult; Aged; Anti-Ulcer Agents; Drug Administration Schedule; Famotidine; Female; Gastroscopy; Humans; Male; Middle Aged; Piperidines; Pyridines; Stomach Ulcer; Treatment Outcome; Wound Healing

2006
Effect of Helicobacter pylori status on intragastric pH during administration of lafutidine or famotidine.
    Hepato-gastroenterology, 2007, Volume: 54, Issue:76

    Topics: Acetamides; Adult; Aged; Famotidine; Gastric Acid; Gastric Acidity Determination; Gastric Mucosa; Helicobacter pylori; Histamine H2 Antagonists; Humans; Hydrogen-Ion Concentration; Male; Middle Aged; Piperidines; Pyridines; Stomach

2007
[Efficacy evaluation of lafutidine for mild reflux esophagitis in Japanese patients].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 2010, Volume: 107, Issue:4

    Topics: Acetamides; Adult; Aged; Asian People; Esophagitis, Peptic; Famotidine; Female; Histamine H2 Antagonists; Humans; Male; Middle Aged; Piperidines; Pyridines

2010
A double-blind, controlled study comparing lafutidine with placebo and famotidine in Japanese patients with mild reflux esophagitis.
    Journal of gastroenterology, 2010, Volume: 45, Issue:12

    Topics: Acetamides; Double-Blind Method; Esophagitis, Peptic; Esophagoscopy; Famotidine; Female; Heartburn; Histamine H2 Antagonists; Humans; Japan; Male; Middle Aged; Piperidines; Pyridines; Treatment Outcome

2010
Efficacy of Lafutidine Versus Famotidine in Patients with Reflux Esophagitis: A Multi-Center, Randomized, Double-Blind, Non-inferiority Phase III Trial.
    Digestive diseases and sciences, 2015, Volume: 60, Issue:6

    Topics: Acetamides; Adult; Aged; Anti-Ulcer Agents; Double-Blind Method; Esophagitis, Peptic; Esophagoscopy; Famotidine; Female; Humans; Male; Medication Adherence; Middle Aged; Omeprazole; Piperidines; Pyridines; Republic of Korea; Severity of Illness Index; Treatment Outcome

2015

Other Studies

51 other study(ies) available for famotidine and piperidines

ArticleYear
Effects of H2-receptor blockers on response of cerebral blood flow to normocapnic hypoxia.
    Anesthesia and analgesia, 1991, Volume: 72, Issue:4

    Topics: Animals; Cerebrovascular Circulation; Dogs; Famotidine; Hemodynamics; Histamine H2 Antagonists; Hypoxia; Injections, Intravenous; Microspheres; Piperidines; Pulmonary Gas Exchange; Ranitidine; Respiration

1991
Time-dependent interaction of a new H2-receptor antagonist, IT-066, with the receptor in the atria of guinea pig.
    Japanese journal of pharmacology, 1991, Volume: 57, Issue:1

    Topics: Animals; Binding, Competitive; Cimetidine; Famotidine; Guinea Pigs; Heart Atria; Heart Rate; Histamine H2 Antagonists; Kinetics; Male; Myocardium; Piperidines; Pyridines; Receptors, Histamine H2; Stimulation, Chemical; Time Factors

1991
H2-receptor antagonism by a novel compound IT-066 assessed from [14C]aminopyrine accumulation in rabbit parietal cells.
    European journal of pharmacology, 1990, Mar-27, Volume: 178, Issue:3

    Topics: Aminopyrine; Animals; Anti-Ulcer Agents; Bucladesine; Carbachol; Cimetidine; Famotidine; Gastric Mucosa; Histamine; Histamine H2 Antagonists; In Vitro Techniques; Male; Piperidines; Pyridines; Rabbits

1990
[Effects of IT-066, a new histamine H2-receptor antagonist, on gastric acid secretion and experimental gastric ulcers in rats and dogs].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1990, Volume: 95, Issue:5

    Topics: Acetates; Animals; Anti-Ulcer Agents; Carbachol; Depression, Chemical; Dogs; Famotidine; Female; Gastric Acid; Histamine Antagonists; Histamine H2 Antagonists; Male; Pentagastrin; Piperidines; Pyridines; Rats; Rats, Inbred Strains; Stomach Ulcer

1990
Antisecretory and antilesional effect of a new histamine H2-receptor antagonist, IT-066, in rats.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 255, Issue:3

    Topics: Animals; Cimetidine; Cold Temperature; Cysteamine; Dose-Response Relationship, Drug; Duodenal Neoplasms; Famotidine; Gastric Acid; Gastric Mucosa; Histamine H2 Antagonists; Indomethacin; Male; Perfusion; Piperidines; Pyridines; Rats; Rats, Inbred Strains; Stomach Neoplasms

1990
Effects of FRG-8701 on gastric acid secretion, gastric mucosal lesions by necrotizing agents and experimental gastric or duodenal ulcer in rats.
    Japanese journal of pharmacology, 1990, Volume: 54, Issue:3

    Topics: Acetamides; Animals; Cimetidine; Duodenal Ulcer; Famotidine; Gastric Acid; Gastric Mucosa; Guinea Pigs; Heart Atria; Heart Rate; Histamine H2 Antagonists; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Piperidines; Pylorus; Rats; Rats, Inbred Strains; Stomach Ulcer

1990
Comparative efficacy of acid reflux inhibition by drug therapy in reflux esophagitis.
    Gastroenterologia Japonica, 1991, Volume: 26, Issue:2

    Topics: Adult; Aged; Chronic Disease; Cisapride; Esophagitis, Peptic; Esophagus; Famotidine; Female; Humans; Hydrogen-Ion Concentration; Male; Monitoring, Physiologic; Omeprazole; Piperidines; Serotonin Antagonists; Stomach

1991
Histamine-induced inositol phosphate accumulation in type-2 astrocytes.
    Biochemical and biophysical research communications, 1991, Jun-14, Volume: 177, Issue:2

    Topics: Animals; Astrocytes; Cells, Cultured; Chlorpheniramine; Famotidine; Histamine; Inositol Phosphates; Piperidines; Pyrilamine; Rats; Rats, Inbred Strains; Receptors, Histamine

1991
Pharmacological control of the human gastric histamine H2 receptor by famotidine: comparison with H1, H2 and H3 receptor agonists and antagonists.
    European journal of clinical investigation, 1989, Volume: 19, Issue:1

    Topics: Adenylyl Cyclases; Cyclic AMP; Famotidine; Gastric Fundus; Histamine; Histamine H2 Antagonists; Humans; In Vitro Techniques; Methylhistamines; Piperidines; Ranitidine; Receptors, Histamine; Stomach Neoplasms; Thiazoles; Triprolidine

1989
Cholinergic effects of histamine-H2 receptor antagonists partly through inhibition of acetylcholinesterase.
    Gastroenterologia Japonica, 1986, Volume: 21, Issue:3

    Topics: Animals; Butyrylcholinesterase; Cholinesterase Inhibitors; Cimetidine; Famotidine; Guinea Pigs; Histamine H2 Antagonists; Humans; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Piperidines; Ranitidine; Thiazoles

1986
[Therapeutic effect of IGN-2098, a new antiulcer drug (H2-antagonist), in the ulcer diminishing period against acetic acid-induced gastric ulcer in rats].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1995, Volume: 105, Issue:3

    Topics: Acetates; Acetic Acid; Animals; Anti-Ulcer Agents; Famotidine; Histamine H2 Antagonists; Male; Piperidines; Pyrimidinones; Rats; Rats, Sprague-Dawley; Stomach Ulcer

1995
(R)-alpha-methylhistamine inhibits ethanol-induced gastric lesions in the rat: involvement of histamine H3 receptors?
    Digestion, 1995, Volume: 56, Issue:2

    Topics: Animals; Ethanol; Famotidine; Gastric Mucosa; Male; Methylhistamines; Piperidines; Rats; Rats, Wistar; Receptors, Histamine H3

1995
[Effects of FRG-8813, a new histamine H2-receptor antagonist, on gastric mucus in rats].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1994, Volume: 104, Issue:5

    Topics: Acetamides; Administration, Oral; Animals; Cimetidine; Dose-Response Relationship, Drug; Famotidine; Gastric Mucosa; Hexoses; Histamine H2 Antagonists; Male; Mucus; Piperidines; Pyridines; Rats; Rats, Sprague-Dawley

1994
Endoscopic ultrasonographic evaluation of gastric ulcer healing on treatment with proton pump inhibitors versus H2-receptor antagonists.
    Scandinavian journal of gastroenterology, 1994, Volume: 29, Issue:12

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Anti-Ulcer Agents; Famotidine; Female; Gastroscopy; Histamine H2 Antagonists; Humans; Lansoprazole; Male; Middle Aged; Nizatidine; Omeprazole; Piperidines; Proton Pump Inhibitors; Stomach Ulcer; Ultrasonography, Interventional; Wound Healing

1994
[Effects of various histamine H2-receptor antagonists on gastrointestinal motility and gastric emptying].
    Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi, 1993, Volume: 29, Issue:4

    Topics: Animals; Cimetidine; Dogs; Dose-Response Relationship, Drug; Famotidine; Gastric Emptying; Gastrointestinal Motility; Histamine H2 Antagonists; Nizatidine; Piperidines; Ranitidine

1993
Pharmacological profiles of the new histamine H2-receptor antagonist N-ethyl-N'-[3-[3-(piperidinomethyl)phenoxy] propyl] urea.
    Arzneimittel-Forschung, 1993, Volume: 43, Issue:2

    Topics: Animals; Cerebral Cortex; Cimetidine; Dogs; Famotidine; Food; Gastric Acid; Guinea Pigs; Heart Atria; Heart Rate; Histamine H2 Antagonists; In Vitro Techniques; Kinetics; Male; Phenylurea Compounds; Piperidines; Pylorus; Rats; Rats, Wistar; Tetragastrin

1993
Healing-promoting action of the new histamine H2-receptor antagonist N-ethyl-N'-[3-[3-(piperidinomethyl)phenoxy]propyl]urea with dual action on chronic gastric and duodenal ulcers induced by acetic acid in rats.
    Arzneimittel-Forschung, 1993, Volume: 43, Issue:2

    Topics: Acetates; Animals; Anti-Ulcer Agents; Dose-Response Relationship, Drug; Duodenal Ulcer; Famotidine; Gastric Mucosa; Histamine H2 Antagonists; Intestinal Mucosa; Male; Phenylurea Compounds; Piperidines; Rats; Rats, Wistar; Stomach Ulcer

1993
Gastric antisecretory effect of FRG-8813, a new histamine H2 receptor antagonist, in rats and dogs.
    European journal of pharmacology, 1993, Apr-28, Volume: 235, Issue:2-3

    Topics: Acetamides; Animals; Cimetidine; Dogs; Famotidine; Gastric Acid; Gastric Mucosa; Histamine; Histamine Agonists; Histamine H2 Antagonists; In Vitro Techniques; Ligation; Male; Perfusion; Piperidines; Pyridines; Rats; Rats, Sprague-Dawley

1993
Effect of the novel histamine H2-antagonist 5,6-dimethyl-2-[4-[3-(1- piperidinomethyl)phenoxy]-(z)-2-butenylamino]-4(1H)-pyrimidine dihydrochloride on histamine-induced gastric acid secretion in Heidenhain pouch dogs.
    Arzneimittel-Forschung, 1993, Volume: 43, Issue:8

    Topics: Administration, Oral; Animals; Cimetidine; Dogs; Dose-Response Relationship, Drug; Famotidine; Gastric Acid; Gastric Mucosa; Histamine; Histamine H2 Antagonists; Injections, Intravenous; Male; Piperidines; Pyrimidinones

1993
[Prokinetic activity and antral inflammation. Usefulness of cisapride combined with H2 antagonists in gastritis].
    La Clinica terapeutica, 1994, Volume: 144, Issue:1

    Topics: Anti-Ulcer Agents; Cisapride; Drug Therapy, Combination; Famotidine; Female; Gastritis; Gastrointestinal Motility; Humans; Male; Piperidines; Pyloric Antrum

1994
Synthesis and biological evaluation of a new reversely linked type of dual histamine H2 and gastrin receptor antagonist.
    Chemical & pharmaceutical bulletin, 1997, Volume: 45, Issue:1

    Topics: Animals; Anti-Ulcer Agents; Benzodiazepines; Drug Design; Famotidine; Gastric Acid; Histamine H2 Antagonists; Molecular Weight; Piperidines; Rats; Receptors, Cholecystokinin

1997
[Effect of a novel antiulcer drug, lafutidine, on experimental chronic gastritis in rats].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1997, Volume: 109, Issue:1

    Topics: Acetamides; Ammonia; Animals; Anti-Ulcer Agents; Cell Count; Chronic Disease; Cimetidine; Famotidine; Gastric Mucosa; Gastritis; Humans; Male; Parietal Cells, Gastric; Piperidines; Pyridines; Rats; Rats, Sprague-Dawley; Taurocholic Acid

1997
Histamine affects interleukin-4, interleukin-5, and interferon-gamma production by human T cell clones from the airways and blood.
    American journal of respiratory cell and molecular biology, 1998, Volume: 18, Issue:5

    Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Albuterol; Asthma; Bronchoalveolar Lavage Fluid; Clone Cells; Cyclic AMP; Dinoprostone; Enzyme Activation; Famotidine; Histamine; Histamine Agonists; Histamine Antagonists; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Impromidine; Interferon-gamma; Interleukin-2; Interleukin-4; Interleukin-5; Lung; Methylhistamines; Piperidines; Pyridines; Ranitidine; T-Lymphocytes; Triprolidine

1998
[Effect of lafutidine, a novel antiulcer agent, on healing and relapse of acetic acid-induced gastric ulcer in rats].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1998, Volume: 111, Issue:3

    Topics: Acetamides; Acetic Acid; Animals; Anti-Ulcer Agents; Cimetidine; Dose-Response Relationship, Drug; Famotidine; Histamine H2 Antagonists; Male; Piperidines; Pyridines; Rats; Rats, Sprague-Dawley; Recurrence; Stomach Ulcer

1998
Role of nitric oxide and prostaglandin in the protective effect of pibutidine hydrochloride, a novel histamine H2-receptor antagonist, on the gastric mucosal lesions in rats.
    General pharmacology, 1998, Volume: 31, Issue:2

    Topics: Animals; Anti-Ulcer Agents; Dinoprostone; Enzyme Inhibitors; Ethanol; Famotidine; Gastric Mucosa; Histamine H2 Antagonists; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Piperidines; Prostaglandins; Pyridines; Rats; Rats, Wistar

1998
Effects of histamine H2 receptor agonists and antagonists on the isolated guinea pig gallbladder.
    Fundamental & clinical pharmacology, 1999, Volume: 13, Issue:1

    Topics: Animals; Benzothiazoles; Dopamine Agents; Famotidine; Gallbladder; Guanidines; Guinea Pigs; Histamine; Histamine Agonists; Histamine H2 Antagonists; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Phenoxypropanolamines; Piperidines; Pyridines; Receptors, Histamine H2; Sincalide; Thiazoles; Triazoles

1999
Interaction of the new histamine H2-receptor antagonist pibutidine hydrochloride with canine cloned H2-receptor expressed cells.
    Arzneimittel-Forschung, 1999, Volume: 49, Issue:1

    Topics: Alanine; Animals; Cell Line; Cimetidine; Dogs; Famotidine; Histamine H2 Antagonists; Ligands; Mice; Mutation; Piperidines; Pyridines; Ranitidine; Receptors, Histamine H2; Transfection

1999
Antiulcer effect of lafutidine on indomethacin-induced gastric antral ulcers in refed rats.
    Japanese journal of pharmacology, 1999, Volume: 80, Issue:3

    Topics: 16,16-Dimethylprostaglandin E2; Acetamides; Administration, Oral; Animals; Anti-Ulcer Agents; Capsaicin; Cimetidine; Denervation; Dose-Response Relationship, Drug; Enzyme Inhibitors; Famotidine; Food; Indomethacin; Male; Nitroarginine; Piperidines; Pyloric Antrum; Pyridines; Rats; Rats, Sprague-Dawley; Stomach Ulcer; Wound Healing

1999
Inhibitory effects of H2-receptor antagonists on platelet function in vitro.
    Human & experimental toxicology, 1999, Volume: 18, Issue:8

    Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Aspirin; Blood Platelets; Cimetidine; Collagen; Famotidine; Female; Heterocyclic Compounds, 1-Ring; Histamine H2 Antagonists; Humans; In Vitro Techniques; Male; Middle Aged; P-Selectin; Piperidines; Platelet Aggregation; Platelet Aggregation Inhibitors; Ranitidine; Structure-Activity Relationship

1999
Long-lasting binding of IT-066 to human histamine H2 receptor.
    Digestive diseases and sciences, 2000, Volume: 45, Issue:4

    Topics: Animals; Anti-Ulcer Agents; CHO Cells; Cimetidine; Cricetinae; Cyclic AMP; Famotidine; Fixatives; Formaldehyde; Histamine H2 Antagonists; Piperidines; Polymers; Protein Binding; Pyridines; Ranitidine; Receptors, Histamine H2

2000
Effect of FRG-8813, a new-type histamine H(2)-receptor antagonist, on the recurrence of gastric ulcer after healing by drug treatment in rats.
    Pharmacology, 2000, Volume: 61, Issue:2

    Topics: Acetamides; Animals; Disease Models, Animal; Endoscopy, Gastrointestinal; Famotidine; Gastric Acidity Determination; Gastrins; Histamine H2 Antagonists; Male; Outcome Assessment, Health Care; Piperidines; Pyridines; Rats; Rats, Wistar; Secondary Prevention; Stomach Ulcer

2000
Influence of different histamine receptor agonists and antagonists on apomorphine-induced licking behavior in rat.
    European journal of pharmacology, 2000, Sep-15, Volume: 404, Issue:1-2

    Topics: Animals; Apomorphine; Chlorpheniramine; Dimaprit; Diphenhydramine; Dopamine Agonists; Drug Interactions; Famotidine; Histamine; Histamine Agonists; Histamine Antagonists; Imidazoles; Male; Piperidines; Ranitidine; Rats; Rats, Sprague-Dawley; Stereotyped Behavior; Thiourea; Toluidines

2000
Effects of vanilloid receptor agonists and antagonists on gastric antral ulcers in rats.
    European journal of pharmacology, 2001, Dec-07, Volume: 432, Issue:2-3

    Topics: Acetamides; Animals; Anti-Ulcer Agents; Capsaicin; Cations; Ditiocarb; Famotidine; Ion Channels; Male; Piperidines; Pyloric Antrum; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Drug; Ruthenium Red; Stomach Ulcer

2001
Potent and long-lasting action of lafutidine on the human histamine H(2) receptor.
    Digestion, 2001, Volume: 64, Issue:3

    Topics: Acetamides; Animals; CHO Cells; Cimetidine; Cricetinae; Cyclic AMP; Dose-Response Relationship, Drug; Famotidine; Histamine H2 Antagonists; Humans; Piperidines; Pyridines; Receptors, Histamine H2; Transfection

2001
Effects of N-alpha-methyl-histamine on human H(2) receptors expressed in CHO cells.
    Gut, 2002, Volume: 50, Issue:6

    Topics: Animals; CHO Cells; Cimetidine; Cricetinae; Cyclic AMP; Famotidine; Female; Histamine Agonists; Histamine Antagonists; Histamine H2 Antagonists; Methylhistamines; Ovary; Piperidines; Receptors, Histamine H2; Receptors, Histamine H3

2002
Lafutidine, a novel histamine H2-receptor antagonist, increases serum calcitonin gene-related peptide in rats after water immersion-restraint stress.
    The Journal of laboratory and clinical medicine, 2003, Volume: 141, Issue:2

    Topics: Acetamides; Animals; Calcitonin Gene-Related Peptide; Famotidine; Histamine H2 Antagonists; Immersion; Male; Piperidines; Pyridines; Rats; Rats, Sprague-Dawley; Restraint, Physical; Stomach Ulcer; Stress, Physiological; Water

2003
Protective role of vanilloid receptor type 1 in HCl-induced gastric mucosal lesions in rats.
    Scandinavian journal of gastroenterology, 2004, Volume: 39, Issue:4

    Topics: Acetamides; Animals; Anti-Ulcer Agents; Capsaicin; Catechols; Diterpenes; Famotidine; Fatty Alcohols; Gastric Mucosa; Hydrochloric Acid; Male; Piperidines; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Drug; Stomach Ulcer

2004
The efficacy of preanesthetic proton pump inhibitor treatment for patients on long-term H2 antagonist therapy.
    Anesthesia and analgesia, 2005, Volume: 101, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Anti-Ulcer Agents; Benzimidazoles; Drug Tolerance; Famotidine; Female; Gastric Acidity Determination; Gastrins; Histamine H2 Antagonists; Humans; Male; Middle Aged; Omeprazole; Piperidines; Pneumonia, Aspiration; Preanesthetic Medication; Proton Pump Inhibitors; Rabeprazole

2005
Histamine increases sickle erythrocyte adherence to endothelium.
    British journal of haematology, 2006, Volume: 132, Issue:4

    Topics: Analysis of Variance; Anemia, Sickle Cell; Cell Adhesion; Cells, Cultured; Endothelial Cells; Endothelium, Vascular; Erythrocytes; Famotidine; Histamine; Histamine Agonists; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Imidazoles; Methylhistamines; P-Selectin; Piperidines; Pyrilamine; Stimulation, Chemical; Thiazoles; Thiourea; Venules

2006
Inhibition of neutrophil activation by lafutidine, an H2-receptor antagonist, through enhancement of sensory neuron activation contributes to the reduction of stress-induced gastric mucosal injury in rats.
    Digestive diseases and sciences, 2007, Volume: 52, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Acetamides; Animals; Anti-Ulcer Agents; Arachidonic Acids; Calcitonin Gene-Related Peptide; Capsaicin; Cells, Cultured; Cyclooxygenase Inhibitors; Disease Models, Animal; Endocannabinoids; Famotidine; Ganglia, Spinal; Gastric Acid; Gastric Mucosa; Histamine H2 Antagonists; Indomethacin; Male; Neurons, Afferent; Neutrophil Activation; Peptide Fragments; Piperidines; Polyunsaturated Alkamides; Pyridines; Rats; Rats, Wistar; Restraint, Physical; Stomach Ulcer; Stress, Psychological

2007
Pharmacokinetic and pharmacodynamic properties of lafutidine after postprandial oral administration in healthy subjects: comparison with famotidine.
    Biological & pharmaceutical bulletin, 2007, Volume: 30, Issue:5

    Topics: Absorption; Acetamides; Administration, Oral; Adult; Famotidine; Gastric Acid; Gastric Acidity Determination; Histamine H2 Antagonists; Humans; Male; Piperidines; Postprandial Period; Pyridines; Tablets; Time Factors

2007
Drug-induced torsades de pointes: data mining of the public version of the FDA Adverse Event Reporting System (AERS).
    Pharmacoepidemiology and drug safety, 2009, Volume: 18, Issue:6

    Topics: Adverse Drug Reaction Reporting Systems; Amiodarone; Anti-Bacterial Agents; Antidepressive Agents; Antipsychotic Agents; Cardiovascular Agents; Databases, Factual; Donepezil; Famotidine; Humans; Indans; Methadone; Mitoxantrone; Piperidines; Torsades de Pointes; United States; United States Food and Drug Administration

2009
A single LC-tandem mass spectrometry method for the simultaneous determination of four H2 antagonists in human plasma.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2009, Dec-01, Volume: 877, Issue:31

    Topics: Acetamides; Calibration; Chromatography, Liquid; Cimetidine; Famotidine; Histamine H2 Antagonists; Humans; Piperidines; Pyridines; Ranitidine; Reproducibility of Results; Tandem Mass Spectrometry; Therapeutic Equivalency

2009
Protective effect of lafutidine, a histamine H2 receptor antagonist, against loxoprofen-induced small intestinal lesions in rats.
    Journal of gastroenterology and hepatology, 2010, Volume: 25 Suppl 1

    Topics: 16,16-Dimethylprostaglandin E2; Acetamides; Ampicillin; Animals; Anti-Bacterial Agents; Anti-Ulcer Agents; Capsaicin; Cimetidine; Disease Models, Animal; Enterobacteriaceae; Famotidine; Histamine H2 Antagonists; Intestinal Mucosa; Intestine, Small; Male; Mucin-2; Nitric Oxide Synthase Type II; Omeprazole; Peptic Ulcer; Peroxidase; Phenylpropionates; Piperidines; Proton Pump Inhibitors; Pyridines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sensory Receptor Cells

2010
Protective effect of roxatidine against indomethacin-induced small intestinal mucosal injury in rats.
    Journal of gastroenterology and hepatology, 2010, Volume: 25 Suppl 1

    Topics: Animals; Anti-Ulcer Agents; Cimetidine; Disease Models, Animal; Famotidine; Histamine H2 Antagonists; Indomethacin; Intestinal Mucosa; Intestine, Small; Male; Mucus; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Peptic Ulcer; Piperidines; Prostaglandins; Rats; Rats, Sprague-Dawley

2010
Anti-ovulatory activity of H2 receptor blockers in albino rabbits--a preliminary study.
    The European journal of contraception & reproductive health care : the official journal of the European Society of Contraception, 2011, Volume: 16, Issue:2

    Topics: Administration, Oral; Animals; Contraceptive Agents; Dose-Response Relationship, Drug; Famotidine; Female; Histamine H2 Antagonists; Histamine Release; Ovulation; Piperidines; Rabbits; Random Allocation; Ranitidine

2011
Correlation between docetaxel-induced skin toxicity and the use of steroids and H₂ blockers: a multi-institution survey.
    Breast cancer research and treatment, 2011, Volume: 130, Issue:2

    Topics: Acetamides; Breast Neoplasms; Chemotherapy, Adjuvant; Dexamethasone; Docetaxel; Erythema; Famotidine; Female; Glucocorticoids; Hand-Foot Syndrome; Histamine H2 Antagonists; Humans; Incidence; Logistic Models; Multivariate Analysis; Neoadjuvant Therapy; Piperidines; Pyridines; Ranitidine; Retrospective Studies; Steroids; Surveys and Questionnaires; Taxoids

2011
Different effects of two types of H2-receptor antagonists, famotidine and roxatidine, on the mucus barrier of rat gastric mucosa.
    Biomedical research (Tokyo, Japan), 2012, Volume: 33, Issue:1

    Topics: Animals; Anti-Ulcer Agents; Famotidine; Gastric Mucins; Gastric Mucosa; Histamine H2 Antagonists; Male; Mucus; Piperidines; Rats; Rats, Wistar

2012
Facilitation of short-term memory by histaminergic neurons in the nucleus accumbens is independent of cholinergic and glutamatergic transmission.
    British journal of pharmacology, 2013, Volume: 170, Issue:1

    Topics: Acetylcholine; Animals; Famotidine; Glutamic Acid; Histamine; Histamine Antagonists; Learning; Male; Memory, Short-Term; Neurons; Nucleus Accumbens; Piperidines; Rats; Rats, Sprague-Dawley; Time Factors

2013
Central histaminergic system interplay with suppressive effects of immune challenge on food intake in chicken.
    British poultry science, 2016, Volume: 57, Issue:2

    Topics: Animals; Appetite Regulation; Chickens; Chlorpheniramine; Famotidine; Feeding Behavior; Food Deprivation; Histamine Antagonists; Infusions, Intraventricular; Lipopolysaccharides; Methylhistidines; Piperidines; Random Allocation

2016
Lafutidine, a histamine H2 receptor antagonist with mucosal protective properties, attenuates 5-fluorouracil-induced intestinal mucositis in mice through activation of extrinsic primary afferent neurons.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2017, Volume: 68, Issue:1

    Topics: Acetamides; Animals; Antimetabolites, Antineoplastic; Diarrhea; Famotidine; Fluorouracil; Histamine H2 Antagonists; Interleukin-1beta; Intestinal Mucosa; Intestines; Male; Mice, Inbred C57BL; Mice, Knockout; Mucositis; Peroxidase; Piperidines; Pyridines; RNA, Messenger; Tumor Necrosis Factor-alpha

2017