famotidine and ibuprofen

famotidine has been researched along with ibuprofen in 42 studies

Research

Studies (42)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	12 (28.57)	29.6817
2010's	28 (66.67)	24.3611
2020's	2 (4.76)	2.80

Authors

Authors	Studies
Hariganesh, K; Prathiba, J	1
Bhilegaonkar, PM; Kiran Babu, S; Shirwaikar, A; Sridhar Reddy, B; Sudheer Kumar, M; Unnikrishnan, MK	1
Birk, JW; Myers, M	1
Peura, D; Schiff, M	1
Bello, AE; Grahn, AY; Kivitz, AJ; Laine, L; Schiff, MH; Taha, AS	1
Chan, FK	1
Holt, RJ; Johnson, KE; Kent, JD; Kuan, R; Malone, D; Peura, DA	1
Deeks, ED	1
Burks, AW; Land, MH; Piehl, MD	1
Peura, D; Tuskey, A	1
Itai, S; Iwao, Y; Kimura, S; Noguchi, S; Sano, S	1
Bello, AE; Grahn, AY; Holt, RJ; Kent, JD; Rice, P	1
El-Kimary, EI; Ragab, MA	1
Ball, J; Bello, AE; Grahn, AY; Holt, RJ; Kent, JD	2
Taha, AS	1
Elzanfaly, ES; Salem, MY; Soudi, AT; Zaazaa, HE	3
Bello, AE; Holt, RJ; Kent, JD	1
Baldoni, HA; Brusau, EV; Dávila, YA; Ellena, JA; Narda, GE; Russo, MG	1
Dressman, J; Litou, C; Psachoulias, D; Reppas, C; Vertzoni, M	1
Habara, M; Haraguchi, T; Ikezaki, H; Kawasaki, I; Kojima, H; Ohkawa, K; Ozeki, M; Uchida, T; Uno, R; Yoshida, M	1
Topliss, JG; Yoshida, F	1
Faller, B; Wohnsland, F	1
Kobayashi, Y; Kohyama, N; Ohbayashi, M; Ohshiro, N; Tsuchiya, A; Yamamoto, T	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Lombardo, F; Obach, RS; Waters, NJ	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Avdeef, A; Tam, KY	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Barber, J; Dawson, S; Kenna, JG; Paul, N; Stahl, S	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1

Reviews

5 review(s) available for famotidine and ibuprofen

Article	Year
HZT-501 (DUEXIS(®); ibuprofen 800 mg/famotidine 26.6 mg) gastrointestinal protection in the treatment of the signs and symptoms of rheumatoid arthritis and osteoarthritis. Expert review of gastroenterology & hepatology, 2012, Volume: 6, Issue:1 Topics: Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Arthritis, Rheumatoid; Drug Combinations; Drug-Related Side Effects and Adverse Reactions; Famotidine; Female; Gastrointestinal Diseases; Gastrointestinal Tract; Histamine H2 Antagonists; Humans; Ibuprofen; Male; Osteoarthritis	2012
Fixed-dose ibuprofen/famotidine: a review of its use to reduce the risk of gastric and duodenal ulcers in patients requiring NSAID therapy. Clinical drug investigation, 2013, Volume: 33, Issue:9 Topics: Anti-Inflammatory Agents, Non-Steroidal; Drug Combinations; Drug Interactions; Duodenal Ulcer; Famotidine; Histamine H2 Antagonists; Humans; Ibuprofen; Stomach Ulcer	2013
The use of H2 antagonists in treating and preventing NSAID-induced mucosal damage. Arthritis research & therapy, 2013, Volume: 15 Suppl 3 Topics: Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Drug Therapy, Combination; Famotidine; Gastrointestinal Diseases; Histamine H2 Antagonists; Humans; Ibuprofen; Intestinal Mucosa; Stomach Ulcer	2013
Risk of upper gastrointestinal ulcers in patients with osteoarthritis receiving single-tablet ibuprofen/famotidine versus ibuprofen alone: pooled efficacy and safety analyses of two randomized, double-blind, comparison trials. Postgraduate medicine, 2014, Volume: 126, Issue:4 Topics: Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Drug Combinations; Duodenal Ulcer; Famotidine; Female; Humans; Ibuprofen; Incidence; Male; Middle Aged; Osteoarthritis; Randomized Controlled Trials as Topic; Stomach Ulcer; Tablets	2014
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Trials

4 trial(s) available for famotidine and ibuprofen

Article	Year
Double-blind randomized trials of single-tablet ibuprofen/high-dose famotidine vs. ibuprofen alone for reduction of gastric and duodenal ulcers. The American journal of gastroenterology, 2012, Volume: 107, Issue:3 Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Chi-Square Distribution; Double-Blind Method; Drug Combinations; Duodenal Ulcer; Endoscopy, Gastrointestinal; Famotidine; Female; Humans; Ibuprofen; Male; Middle Aged; Proportional Hazards Models; Risk Factors; Stomach Ulcer; Treatment Outcome	2012
One-year open-label safety evaluation of the fixed combination of ibuprofen and famotidine with a prospective analysis of dyspepsia. Current medical research and opinion, 2015, Volume: 31, Issue:3 Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Drug Combinations; Drug Monitoring; Dyspepsia; Endoscopy, Gastrointestinal; Famotidine; Female; Histamine H2 Antagonists; Humans; Ibuprofen; Incidence; Male; Middle Aged; Patient Compliance; Severity of Illness Index; Stomach Ulcer; Treatment Outcome	2015
One-year safety of ibuprofen/famotidine fixed combination versus ibuprofen alone: pooled analyses of two 24-week randomized, double-blind trials and a follow-on extension. Current medical research and opinion, 2015, Volume: 31, Issue:3 Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Drug Combinations; Drug Monitoring; Dyspepsia; Endoscopy, Gastrointestinal; Famotidine; Female; Histamine H2 Antagonists; Humans; Hypertension; Ibuprofen; Incidence; Male; Middle Aged; Patient Compliance; Severity of Illness Index; Stomach Ulcer; Treatment Outcome	2015
Gastroprotective efficacy and safety of single-tablet ibuprofen/famotidine vs ibuprofen in older persons. The Physician and sportsmedicine, 2015, Volume: 43, Issue:3 Topics: Adult; Age Factors; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Arthritis, Rheumatoid; Double-Blind Method; Drug Combinations; Duodenal Ulcer; Famotidine; Female; Gastrointestinal Diseases; Humans; Ibuprofen; Male; Middle Aged; Osteoarthritis; Risk Factors; Stomach Ulcer; Tablets; United States	2015

Other Studies

33 other study(ies) available for famotidine and ibuprofen

Article	Year
Effect of dimethylglycine on gastric ulcers in rats. The Journal of pharmacy and pharmacology, 2000, Volume: 52, Issue:12 Topics: Animals; Anti-Ulcer Agents; Dose-Response Relationship, Drug; Famotidine; Gastric Juice; Glutathione; Hydrogen-Ion Concentration; Ibuprofen; Ligation; Malondialdehyde; Pylorus; Rats; Rats, Wistar; Sarcosine; Severity of Illness Index; Stomach Ulcer; Stress, Physiological	2000
Antiinflammatory and antiulcer activities of phytic acid in rats. Indian journal of experimental biology, 2004, Volume: 42, Issue:2 Topics: Animals; Anti-Inflammatory Agents; Anti-Ulcer Agents; Cold Temperature; Ethanol; Famotidine; Gastric Mucosa; Hemorrhage; Ibuprofen; Malondialdehyde; Necrosis; Phytic Acid; Plant Extracts; Rats; Stomach Ulcer; Stress, Physiological; Sulfhydryl Compounds	2004
A fixed dose combination of ibuprofen and famotidine. Expert opinion on investigational drugs, 2009, Volume: 18, Issue:9 Topics: Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Clinical Trials, Phase III as Topic; Drug Combinations; Famotidine; Gastrointestinal Diseases; Humans; Ibuprofen; Pain	2009
A fixed-dose combination ibuprofen and famotidine (Duexis). The Medical letter on drugs and therapeutics, 2011, Oct-31, Volume: 53, Issue:1376 Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Drug Combinations; Duodenal Ulcer; Famotidine; Histamine H2 Antagonists; Humans; Ibuprofen; Osteoarthritis; Stomach Ulcer	2011
Editorial: single-tablet ibuprofen/double-dose famotidine for reduction of gastric and duodenal ulcers (REDUCE Trials): what can be reduced? The American journal of gastroenterology, 2012, Volume: 107, Issue:3 Topics: Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Duodenal Ulcer; Famotidine; Female; Humans; Ibuprofen; Male; Stomach Ulcer	2012
Budget impact modeling for a single-tablet formulation of ibuprofen and famotidine for prevention of upper gastrointestinal ulcers in patients with osteoarthritis and/or rheumatoid arthritis. Clinical therapeutics, 2013, Volume: 35, Issue:3 Topics: Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Arthritis, Rheumatoid; Drug Combinations; Drug Costs; Famotidine; Humans; Ibuprofen; Models, Economic; Osteoarthritis; Patient Compliance; Stomach Ulcer; Tablets	2013
Near fatal anaphylaxis from orally administered gelatin capsule. The journal of allergy and clinical immunology. In practice, 2013, Volume: 1, Issue:1 Topics: Administration, Oral; Adrenergic alpha-Agonists; Anaphylaxis; Anti-Allergic Agents; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Capsules; Child; Diphenhydramine; Epinephrine; Famotidine; Female; Follow-Up Studies; Gelatin; Histamine H2 Antagonists; Humans; Ibuprofen; Prednisone; Treatment Outcome	2013
Impact of active ingredients on the swelling properties of orally disintegrating tablets prepared by microwave treatment. International journal of pharmaceutics, 2014, Jul-01, Volume: 468, Issue:1-2 Topics: Acetaminophen; Administration, Oral; Drug Stability; Famotidine; Hardness; Ibuprofen; Kinetics; Microwaves; Solubility; Tablets; Technology, Pharmaceutical; Transition Temperature; Water	2014
Derivative emission spectrofluorimetry: Application to the analysis of newly approved FDA combination of ibuprofen and famotidine in tablets. Luminescence : the journal of biological and chemical luminescence, 2015, Volume: 30, Issue:6 Topics: Calibration; Drug Combinations; Famotidine; Hydrogen-Ion Concentration; Ibuprofen; Limit of Detection; Reproducibility of Results; Sensitivity and Specificity; Solvents; Spectrometry, Fluorescence; Tablets	2015
The ibuprofen-famotidine combined pill - a promise fulfilled. Current medical research and opinion, 2015, Volume: 31, Issue:3 Topics: Anti-Inflammatory Agents, Non-Steroidal; Dyspepsia; Famotidine; Female; Histamine H2 Antagonists; Humans; Hypertension; Ibuprofen; Male; Stomach Ulcer	2015
Application of the ratio difference spectrophotometry to the determination of ibuprofen and famotidine in their combined dosage form: comparison with previously published spectrophotometric methods. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2015, May-15, Volume: 143 Topics: Anti-Inflammatory Agents, Non-Steroidal; Drug Combinations; Famotidine; Ibuprofen; Spectrophotometry, Ultraviolet	2015
Development and validation of chromatographic methods for simultaneous determination of ibuprofen and famotidine in presence of related substances in pharmaceutical formulations. Acta chimica Slovenica, 2015, Volume: 62, Issue:1 Topics: Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Famotidine; Ibuprofen; Molecular Structure	2015
Multivariate Validated Models for Simultaneous Determination of Ibuprofen and Famotidine in the Presence of Related Substances. Journal of AOAC International, 2018, Jul-01, Volume: 101, Issue:4 Topics: Calibration; Drug Contamination; Famotidine; Ibuprofen; Least-Squares Analysis; Limit of Detection; Models, Statistical; Multivariate Analysis; Reproducibility of Results; Spectrophotometry, Ultraviolet; Tablets	2018
Rational Design of a Famotidine-Ibuprofen Coamorphous System: An Experimental and Theoretical Study. The journal of physical chemistry. B, 2018, 09-20, Volume: 122, Issue:37 Topics: Antacids; Anti-Inflammatory Agents, Non-Steroidal; Density Functional Theory; Drug Compounding; Drug Design; Famotidine; Hydrogen Bonding; Ibuprofen; Models, Chemical; Molecular Dynamics Simulation; Molecular Structure; Spectroscopy, Fourier Transform Infrared	2018
Measuring pH and Buffer Capacity in Fluids Aspirated from the Fasted Upper Gastrointestinal Tract of Healthy Adults. Pharmaceutical research, 2020, Jan-27, Volume: 37, Issue:3 Topics: Bicarbonates; Bile Acids and Salts; Body Fluids; Buffers; Famotidine; Gastrointestinal Absorption; Humans; Hydrogen-Ion Concentration; Ibuprofen; Intestine, Small; Salts; Stomach; Upper Gastrointestinal Tract	2020
Masking the Taste of Fixed-Dose Combination Drugs: Particular NSAIDs Can Efficiently Mask the Bitterness of Famotidine. Chemical & pharmaceutical bulletin, 2023, Volume: 71, Issue:2 Topics: Anti-Inflammatory Agents, Non-Steroidal; Famotidine; Flurbiprofen; Ibuprofen; Naproxen; Taste	2023
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
High-throughput permeability pH profile and high-throughput alkane/water log P with artificial membranes. Journal of medicinal chemistry, 2001, Mar-15, Volume: 44, Issue:6 Topics: Alkanes; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Membranes, Artificial; Octanols; Permeability; Pharmaceutical Preparations; Solubility; Water	2001
Renal transport of organic compounds mediated by mouse organic anion transporter 3 (mOat3): further substrate specificity of mOat3. Drug metabolism and disposition: the biological fate of chemicals, 2004, Volume: 32, Issue:5 Topics: Allopurinol; Animals; Biological Transport; Dose-Response Relationship, Drug; Female; Kidney; Male; Mice; Oocytes; Organic Anion Transporters, Sodium-Independent; Substrate Specificity; Xenopus laevis	2004
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data. European journal of medicinal chemistry, 2009, Volume: 44, Issue:11 Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability? Journal of medicinal chemistry, 2010, May-13, Volume: 53, Issue:9 Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Prediction of drug intestinal absorption by new linear and non-linear QSPR. European journal of medicinal chemistry, 2011, Volume: 46, Issue:1 Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics	2011
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Cholestasis; Drug-Related Side Effects and Adverse Reactions; Humans; Insecta; Rats; Risk Factors	2012