famotidine has been researched along with cimetidine in 314 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 83 (26.43) | 18.7374 |
| 1990's | 155 (49.36) | 18.2507 |
| 2000's | 48 (15.29) | 29.6817 |
| 2010's | 25 (7.96) | 24.3611 |
| 2020's | 3 (0.96) | 2.80 |
| Authors | Studies |
|---|---|
| Ianelli, S; Pelizzi, G | 1 |
| Abu-Khalaf, M; Irshaid, Y | 1 |
| Gannon, JM; Hilleman, DE; Mathias, RJ; Mohiuddin, SM; Thalken, LJ; Williams, MA | 1 |
| Fraser, AG; Hudson, M; Pounder, RE; Rosalki, SB; Sawyerr, AM; Smith, M | 1 |
| Elezoglou, A; Kounenis, G; Koutsoviti-Papadopoulou, M; Voutsas, A | 1 |
| Carrasco, M; del Villar, E; Gaule, C; Vega, P | 1 |
| Arisawa, T; Asai, J; Goto, H; Hase, S; Suzuki, T; Tsukamoto, Y | 1 |
| Daifotis, Z; Danou, K; Kaniaris, P; Karayannacos, P; Sabatakaki, A | 1 |
| Miller, TA; Robinson, M | 1 |
| Harada, T; Irifune, M; Matsunaga, T; Ogino, S | 1 |
| Affarah, HB; Khasawneh, SM | 1 |
| Gardner, JD; Jensen, RT; Maton, PN; Metz, DC; Norton, JA; Pisegna, JR; Slimak, GG | 1 |
| Wesdorp, IC | 1 |
| Hehir, D; Stuart, RC | 1 |
| Holdcroft, C | 1 |
| Kawai, K | 1 |
| Michocki, RJ; Richardson, JP | 1 |
| Grebenev, AL; Kkhorshed, AM; Miagkova, LP | 1 |
| Baraona, E; Caballería, J; Deulofeu, R; Hernández-Muñoz, R; Lieber, CS; Rodés, J | 1 |
| Nwokolo, CU; Pounder, RE; Sawyerr, AM; Smith, JT | 1 |
| Guram, M; Holt, S; Howden, CW | 1 |
| Aihara, H; Hirose-Kijima, H; Muramatsu, M; Otomo, S | 1 |
| Burde, R; Buschauer, A; Seifert, R | 1 |
| Krielaart, MJ; van Buuren, KJ; Veenstra, DM | 1 |
| Hiramatsu, A; Inoue, K; Kitajima, T; Maruoka, M; Mizuno, T; Nakano, T; Okuhira, M | 1 |
| Baraona, E; DiPadova, C; Frezza, M; Gentry, RT; Lieber, CS; Roine, R | 1 |
| Miyazaki, T; Nagasaka, H; Naito, H | 1 |
| Brouard, A; Conort, O; Terrier, JL | 1 |
| Davydov, SM; Grigor'ev, PIa; Iakovenko, EP; Isakov, VA; Vasil'eva, ZI | 1 |
| Fraser, AG; Hudson, M; Pounder, RE; Prewett, EJ; Rosalki, SB; Sawyerr, AM | 1 |
| Collen, MJ; Sheridan, MJ | 1 |
| Camerini, S; Cantarelli, A; Nolli, M; Spotti, M | 1 |
| Smith, T | 1 |
| Fagan, TC; Fennerty, B; Lipsy, RJ | 1 |
| Aihara, H; Isobe, Y; Muramatsu, M; Otomo, S | 1 |
| Liao, CH; Pan, S | 1 |
| Calogero, A; Casciani, CU; Cervelli, V; Famularo, G; Filingeri, V; Giacomelli, R; Iacona, A; Rosati, R; Tonietti, G | 1 |
| Halabi, A; Hinrichsen, H; Kirch, W | 1 |
| Konda, Y; Matozaki, T; Matsuda, K; Nagao, M; Nakano, O; Nishisaki, H; Sakamoto, C; Wada, K | 1 |
| Aihara, H; Isobe, Y; Muramatsu, M; Nagai, H; Otomo, S | 1 |
| Chastre, E; Di Gioia, Y; Emami, S; Gespach, C | 1 |
| Fujihara, A; Kamato, T; Miyata, K; Takeda, M | 2 |
| Baraona, E; Caballeria, J; Greenstein, R; Hernández-Muñoz, R; Lieber, CS; Uppal, R | 1 |
| Chida, Y; Nishikawa, M; Ohnishi, H; Sekine, A; Shibata, M; Yamaura, T | 1 |
| Gavey, C; Nwokolo, CU; Pounder, RE; Sawyerr, A; Smith, JT | 1 |
| Castellano, J; Lamothe, PH; Lemole, GM; McNicholas, KW; Rao, E; Serra, AJ; Woronick, CL | 1 |
| Honda, K; Kamato, T; Miyata, K; Nishida, A | 1 |
| Duvnjak, M; Jagic, V; Mise, S; Petek, M; Rotkvic, I; Rucman, R; Seiwerth, S; Sikiric, P; Suchanek, E; Zjacic-Rotkvic, V | 1 |
| Franko, TG; Oh, T | 1 |
| Bedini, OA; Cesolari, JA; Laudanno, OM; San Miguel, P | 1 |
| Karlstadt, RG; Palmer, RH | 1 |
| Kishikawa, K; Miyashita, K; Namiki, A; Saitoh, K | 1 |
| Hagiwara, T; Iwasaki, H; Namiki, A; Nishikawa, T; Omote, K; Tsuchida, H | 1 |
| Eguchi, M; Ishigami, M; Maeda, T; Miyake, H; Sezai, Y; Yabuki, S | 1 |
| Lee, FI | 1 |
| Kalinin, AP; Nechaĭ, AI; Trofimov, VT | 1 |
| Kari, PH; Lu, AY; Vyas, KP; Wang, RW | 1 |
| Arai, I; Muramatsu, M; Oomura, Y; Otomo, S; Shiraishi, T; Usuki-Ito, C | 1 |
| Howard, TJ; Passaro, E | 1 |
| Booth, SN; Cochran, KM; Cottrell, J; Crowe, J; Dickinson, RJ; Kennedy, NP; Lee, FI; Mann, SG | 1 |
| Hirsch, E | 1 |
| Amoruso, A; Barone, M; Di Leo, A; Francavilla, A; Ingrosso, M; Makowka, L; Panella, C; Polimeno, L; Starzl, TE | 1 |
| Fujimoto, K; Fukagawa, K; Ookuma, K; Sakata, T; Shiraishi, T; Wada, H; Yoshimatsu, H | 1 |
| Chremos, AN; Lin, ET; Sambol, NC; Upton, RA; Williams, RL | 1 |
| Levine, JB | 1 |
| De Natale, F; De Natale, G; Marino, A | 1 |
| Bast, A; Smid, K; Timmerman, H | 1 |
| Rovers, JP; Souney, PF | 1 |
| Dammann, HG; Dreyer, M; Gottlieb, WR; Müller, P; Simon, B; Wolf, N | 1 |
| Alvarez, A; Barrio, E; Conchillo, F; Dieguez, P; Forné, M; Muñoz, M; Panés, J; Rodrigo, L; Viver, J; Zozaya, JM | 1 |
| Bode, JC; Klotz, U; Krishna, DR; Walker, S | 1 |
| Calogero, A; Cramarossa, L; Famularo, G; Filingeri, V; Giacomelli, R; Iacona, A; Nardi, S; Rosati, R; Sacchetti, S; Stortoni, F | 1 |
| Ishigami, M; Maeda, T; Sezai, Y; Shimada, Y; Yabuki, S | 1 |
| Chapman, JM; Kosh, JW; Sowell, JW | 1 |
| Gardner, JD; Jensen, RT; Maton, PN | 1 |
| Di Sarra, B; Re, L | 1 |
| Galbraith, RA; Jellinck, PH | 1 |
| Cherner, JA; Chremos, AN; Ciarleglio, CA; Collen, MJ; Cornelius, MJ; Gardner, JD; Howard, JM; Jensen, RT; Maton, PN; McArthur, KE | 1 |
| Chremos, AN; Gamal, MA; Graham, DY; Smith, JL | 1 |
| Cook, PG; Mangel, AW; Pendleton, RG; Shepherd-Rose, A | 1 |
| Chremos, AN; Huber, PB; Kuljian, B; McCallum, RW; Tupy-Visich, MA | 1 |
| Arvela, P; Klotz, U; Rosenkranz, B | 1 |
| Smith, JL | 1 |
| Bianchi Porro, G | 1 |
| Kuroiwa, Y; Misawa, S; Tanaka, E | 1 |
| Greenblatt, DJ; Harmatz, JS; Locniskar, A; Shader, RI; Zinny, MA | 1 |
| Aono, M; Mizuta, K; Moriga, M; Narusawa, H | 1 |
| Imai, Y; Inada, M; Kawata, S; Minami, Y; Noda, S; Tamura, S; Tarui, S | 1 |
| Gardner, JD; Howard, JM; Jensen, RT; Maton, PN; Slaff, JI; Vinayek, R; Wank, SA | 1 |
| Arvela, P; Klotz, U; Pasanen, M; Pelkonen, O; Sotaniemi, E | 1 |
| Hashimoto, Y; Iwatsuki, N; Koga, Y | 1 |
| Mahachai, V; Thomson, AB | 1 |
| Gardner, JD; Howard, JM; Jensen, RT; Maton, PN; Vinayek, R; Wank, SA | 1 |
| Hagiwara, T; Namiki, A; Omote, K; Sumita, S; Takahashi, T; Ujike, Y | 1 |
| Humphries, TJ | 1 |
| Baba, S; Daikuhara, Y; Gohda, E; Hirono, S; Miyazaki, H; Nakayama, H; Sakiyama, O; Takahashi, K; Tamada, F; Tsubouchi, H | 1 |
| Freston, JW | 1 |
| Bertaccini, G; Coruzzi, G; Poli, E | 1 |
| Chiou, R; Chremos, AN; Lin, JH; Williams, R; Yeh, KC | 1 |
| Heim, J; Kaufmann, D; Krammisch, H; Mappes, A; Merki, HS; Neumann, J; Roehmel, J; Scheurle, E; Walt, RP; Witzel, L | 1 |
| Akamatsu, K; Hirabayashi, Y; Kanaoka, M; Masumoto, S; Nakanishi, K; Nishinobu, M; Ohta, Y; Okada, S; Sakaue, H; Sasaki, T | 1 |
| Dicke, JM; Henderson, GI; Johnson, RF; Kuehl, TJ; Schenker, S | 1 |
| Amplatz, S; Comberlato, M; de Pretis, G; Dobrilla, G | 1 |
| Brambilla, A; De Paoli, AM; Ghiorzi, A; Giachetti, A | 1 |
| Berardi, RR; Nostrant, TT; Tankanow, RM | 1 |
| Kuroiwa, Y; Misawa, S; Nakamura, K; Tanaka, E | 1 |
| Argenbright, LS; Lu, AY; Miwa, GT; Wang, RW | 1 |
| Gillam, EM; Mason, SR; Reilly, PE | 1 |
| Luskin, AT; Tomasko, MA | 1 |
| Klotz, U; Kuhlmann, U; Machleidt, C; Mettang, T; Weber, J | 1 |
| Berta, L; Crua, MR; Dusio, P; Fazzari, A; Fortunati, N; Frairia, R; Gaidano, G | 1 |
| Franco, P; Guidobono, F; Netti, C; Pecile, A; Sibilia, V; Villa, I | 1 |
| Nakamura, K; Tanaka, E | 1 |
| Astengo, M; Basso, C; Bennicelli, C; Camoirano, A; De Flora, S; Zanacchi, P | 1 |
| Brockmeier, D; Lameire, N; Rosenkranz, B | 1 |
| Ciarleglio, CA; Collen, MJ; Stanczak, VJ | 1 |
| Crean, GP; Fullarton, GM; Laferla, G; McColl, KE | 1 |
| Fölsch, UR; Hartmann, H | 1 |
| Ahmed, W; Qureshi, H; Zuberi, SJ | 1 |
| Baronti, A; Di Carlo, S; Verdiani, P | 1 |
| Bellini, M; Cipparrone, G; Costa, F; Greco, A; Maltinti, G; Marchi, S; Polloni, A | 1 |
| Imai, Y; Inada, M; Kawata, S; Minami, Y; Tamura, S; Tarui, S | 1 |
| Lewis, JH | 1 |
| Dammann, HG; Mueller, P; Simon, B; Walter, TA | 1 |
| Burget, DW; Howden, CW; Hunt, RH; Jones, DB | 1 |
| Hazama, H; Murase, T; Okuno, H; Sameshima, Y; Shiozaki, Y | 1 |
| Dammann, HG; Müller, P; Simon, B; Walter, TA | 1 |
| Maeno, H; Takagi, T; Takeda, M | 2 |
| Maeno, H; Takagi, T; Takeda, M; Yashima, Y | 1 |
| Harada, M; Maeno, H; Terai, M | 1 |
| Ishihara, Y; Okabe, S | 1 |
| Dammann, HG; Müller, P; Simon, B | 1 |
| Chung, C; Clineschmidt, BV; Cook, P; Pendleton, RG; Torchiana, ML; Wiese, S | 1 |
| Miwa, T; Tani, N; Watanabe, K; Watanabe, T; Watanabe, Y | 1 |
| Dammann, HG; DeVries, JX; Koroknay, B; Müller, P; Simon, B; Staiger, C; Weber, E | 1 |
| Miwa, M; Miwa, T; Tani, N | 1 |
| Fujiwara, T; Kohchi, M; Matsumoto, H; Miyoshi, A; Nakamura, M; Ohe, K | 1 |
| Mori, H | 1 |
| Dammann, HG; Devries, JX; Korodnay, B; Müller, P; Simon, B; Staiger, C; Weber, E | 1 |
| Harada, M; Kaneko, H; Kotera, H; Mitsuma, T; Nagai, H; Uchida, K | 1 |
| Mann, SG; Panos, MZ; Reilly, TG; Walt, RP | 1 |
| Morosco, RS; Nahata, MC; Sabados, BK; Weber, TR | 1 |
| Bachmann, K; Jauregui, L; King, JD; Miller, K; Reese, JH; Schwartz, J; Scott, M; Stepanavage, M; Sullivan, TJ; Yeh, KC | 1 |
| Chase, SL | 1 |
| Bosron, WF; Davis, GJ; Hurley, TD; Kedishvili, NY; Li, TK; Peggs, CF; Stone, CL; Thomasson, HR | 1 |
| Collier, PS; Hughes, CM; Swanton, JG | 2 |
| Amsden, GW; D'Andrea, DT; Goss, TF; Harrison, NJ; Schentag, JJ | 1 |
| Hahm, KB; Kang, JK; Kim, WH; Lee, SI; Park, IS | 1 |
| Bowling, MK; Chen, TL; Donehower, RC; McGuire, WP; Rowinsky, EK; Slichenmyer, WJ | 1 |
| Kelly, DA | 1 |
| Kagoshima, M; Kodaira, H; Shimada, H | 1 |
| Bachmann, KA; Jauregui, L; Levine, L; Miller, K; Reese, J; Sullivan, TJ | 1 |
| Akaike, N; Munakata, M | 1 |
| Fujihara, A; Kamato, T; Miyata, K; Nishida, A; Takeda, M; Yuki, H | 1 |
| Aoki, T; Fukuda, S; Hanyu, N; Hashimoto, Y; Iikura, M; Ohira, Y | 1 |
| Bergmann, JF; Blanc, LE; Delchier, JC; Dhumeaux, D; Dutreuil, C; Mallat, A; Roudot-Thoraval, F; Simonneau, G; Trout, H | 1 |
| Bachmann, KA; Jauregui, L; Levine, L; Miller, K; Reese, JH; Sullivan, TJ | 1 |
| Gugler, R | 1 |
| Fleisher, D; Hu, Z; Hui, YF; Kolars, J | 1 |
| Besancon, M; Helander, H; Sachs, G; Scott, DR | 1 |
| Bast, A; Ching, TL; de Jong, J | 1 |
| Meiser, BM; Muschiol, F; Nollert, G; Pfeiffer, M; Reichart, B; Reichenspurner, H; Uberfuhr, P; Vetter, HO; Wagner, F | 1 |
| Horikoshi, T; Matsuzaki, T; Sekiguchi, T | 1 |
| Cuccurullo, F; De Gioia, S; Festi, D; Grossi, L; Lapenna, D; Marzio, L; Mezzetti, A | 1 |
| Braithwaite, R; Gibson, GJ; Hale, KA; Kendall, MJ; Langman, MJ; Spannuth, F; Walt, RP | 1 |
| Duke, JC; Imes, NK; Mellow, MH; Orr, WC | 1 |
| Gross, AS; Simmons, N; Somogyi, AA | 1 |
| Aita, H; Chaki, K; Hori, Y; Itoh, Z; Morita, H; Seiki, M; Tagashira, E; Ueki, S; Yoneta, T | 1 |
| Notar-Francesco, V; Raffaniello, RD; Raufman, JP; Straus, EW | 1 |
| Hamada, K; Kobayashi, F; Sekiguchi, H; Taga, F; Uchida, H | 1 |
| Khoo, NK; Lala, PK; Saarloos, MN | 1 |
| Chida, Y; Inaba, N; Ohnishi, H; Onodera, S; Shibata, M; Yamaura, T | 1 |
| Kriegler, A; van der Walt, BJ; van Zyl, JM | 1 |
| Bhasin, DK; Khosla, PP; Sachdev, A; Saha, N; Sankaranahyanan, A; Sharma, PL; Singh, K | 1 |
| Euler, AR; Hahne, WF; Jensen, RT; Norton, JA; Vinayek, R | 1 |
| Ikarashi, Y; Kawano, O; Misaki, N; Ohba, S; Uchida, M | 1 |
| Davis, RL; Egli, D; Hashimoto, F | 1 |
| Bondoux, D; Emami, S; Gespach, C; Haimart, M; Launay, JM; Mutel, V; Oset-Gasque, MJ | 1 |
| Jacyna, MR; Levi, AJ; Miller, RJ; O'Reilly, S; Ross, J; Ryder, SD | 1 |
| Jarboe, LA; Lee, RT; Solomon, SD; Wolfe, MM; Wolff, S | 1 |
| Ben-Joseph, R; Oh, T; Russell, WL; Segal, R | 2 |
| Akalin, E; Altaca, G; Gür, D; Onat, D; Sayek, I | 1 |
| Ben-Joseph, R; Russell, WL; Segal, R | 1 |
| Guelen, PJ; van den Biggelaar-Martea, M; Verwey-van Wissen, CP; Vree, ML; Vree, TB | 1 |
| Helfaer, MA; Kirsch, JR; Traystman, RJ; Tung, WS | 1 |
| Dal Negro, R; Pomari, C; Turco, P | 1 |
| Kanaoka, S; Watanabe, K; Yamamoto, M; Yano, S | 1 |
| Collier, DS; McGuire, TR; Rossi, SJ; Schaaf, LJ; Shaefer, MS; Stratta, RJ | 1 |
| Campbell, NR; Chan, SC; Granberg, K; Hasinoff, BB; Pap, KM; Partlow, ES | 1 |
| Copius Peereboom-Stegeman, JH; Russel, FG; Van der Aa, EM; Wouterse, AC | 1 |
| Iga, T; Kawakami, J; Sawada, Y; Shimokawa, M; Yamamoto, K | 1 |
| Battaglia, G; Di Mario, F; Grasso, G; Leandro, G; Vianello, F; Vigneri, S | 1 |
| Csepregi, A; Nemesánszky, E | 1 |
| Degtiareva, II; Egorova, IT; Gaĭsenko, AV; Kharchenko, NV; Petrović, S; Semeunović, S | 1 |
| Chakrabarti, A; Goenka, MK; Gupta, O; Kochhar, R; Kumar, A; Mehta, SK; Talwar, P | 1 |
| Hernández-Muñoz, R; Montiel-Ruíz, F | 1 |
| Kerstein, MD; Rowland, M; Shanavas, Z; Zeltsman, D | 1 |
| Paradowski, L; Salomon, A; Szelag, A | 1 |
| Inaba, N; Onodera, S; Shibata, M; Suzuki, T; Tanaka, M; Yamaura, T | 1 |
| Berstad, A; Hatlebakk, JG | 1 |
| Conejo, L; Ortiz, JA; Palop, D; Romero, A; Sacristán, A; Villamayor, F | 1 |
| Czyzyk, A; Lao, B; Muszyński, J; Szczepanik, Z; Szutowski, M | 1 |
| Itoh, T; Kamisaki, Y; Kawasaki, H; Kishimoto, Y; Kitano, M; Nakamoto, K; Wada, K | 1 |
| Florholmen, J; Løvhaug, N; Støa-Birketvedt, G; Vonen, B | 1 |
| Adachi, Y; Iso, Y; Kitano, S; Matsumata, T; Shiota, E; Yoh, R | 1 |
| Biron, CR | 1 |
| Aoyama, M; Arai, Y; Ohnishi, H; Onodera, S; Shibata, M; Tanaka, M; Yamaura, T | 1 |
| Cottrell, J; Grimley, CE; Mann, SG; Nwokolo, CU; Raskin, S; Reilly, TG; Usselmann, B | 1 |
| Alewijnse, AE; Hoffmann, M; Leurs, R; Smit, MJ; Timmerman, H; Verzijl, D | 1 |
| Aster, RH; Curtis, BR; Gentilini, G | 1 |
| Berlin, JA; Burnham, D; Weinberg, DS | 1 |
| Chan, CK; Cheung, E; Ching, TY; Chu, KM; Kong, Y; Kou, M; Kumana, CR; Lam, SK; Seto, WH | 1 |
| Blayney-Chandramouli, J; McCoy, S; Mutnick, A | 1 |
| Higuchi, S; Isobe, Y; Kaku, S; Kiuchi, Y; Muramatsu, M; Tanaka, M | 1 |
| Chang, BL; Ho, C; Hsu, SY; Huang, HM; Shaw, CY | 1 |
| Decktor, D; Houle, JM; Pierce, CH | 1 |
| Figge, HL; Hamilton, RA; Kowalsky, SF | 1 |
| Chow, MS; Jay, GT; Quercia, RA; Quintiliani, R | 1 |
| Drea, EJ | 1 |
| Jennings, RH; Wetmore, RW | 1 |
| Ishiguro, I; Kobayashi, T; Ohta, Y | 1 |
| Alekseenko, SA; Timoshin, SS | 1 |
| Akamatsu, H; Maekawa, N; Mikawa, K; Nishina, K; Niwa, Y; Obara, H; Shiga, M | 1 |
| Itoh, Z; Matsunaga, Y; Tamaki, H; Ueki, S; Yoneta, T | 1 |
| Aoyama, M; Arai, Y; Inaba, N; Nishizawa, A; Onodera, S; Sekine, Y; Shibata, M; Suzuki, T; Tanaka, M | 1 |
| Ayukawa, O; Kariyazono, H; Moriyama, Y; Nakamura, K; Shinkawa, T; Taira, A; Toyohira, H; Yamada, K; Yamaguchi, T; Yamashita, T; Yotsumoto, G | 1 |
| Davis, SS; He, P; Illum, L | 1 |
| Horiuchi, Y; Ikezawa, K | 1 |
| Asano, T; Fukushima, Y; Kajiwara, T; Katsube, T; Mori, H; Ogawa, K; Ohkawa, SI; Otsuka, H; Saitoh, T; Takahashi, H; Tamai, M | 1 |
| Kawabe, T; Kobayashi, K; Matsumoto, S; Morishima, T; Okamoto, T | 1 |
| Baj, J; Burak, B; Burdan, F; Górny, D; Wyskiel, M | 1 |
| Chen, SH; Ho, YH; Ko, HS; Wu, HL; Wu, SM | 2 |
| Chen, CH; Ho, CS; Kao, CR; Sheu, JJ; Yuan, RY | 1 |
| Anai, M; Asano, T; Fukushima, Y; Ishikawa, M; Ishikawa, T; Kajiwara, T; Katsube, T; Ogawa, K; Ohkawa, S; Omata, M; Otsuka, H; Saitoh, T | 1 |
| Fujiwara, H; Itoh, T; Kubota, T; Okugawa, K; Ueda, Y; Yamagishi, H; Yamamoto, Y; Yamashita, T; Yano, Y; Yoshimura, T | 1 |
| Basit, AW; Lacey, LF; Newton, JM | 1 |
| Healey, MA; Rebuck, JA; Rogers, FB; Wade, EE | 1 |
| Anai, M; Asano, T; Fukushima, Y; Ishikawa, M; Ishikawa, T; Kajiwara, T; Katsube, T; Mori, H; Ogawa, K; Ohkawa, S; Omata, M; Otsuka, H; Saitoh, T; Takahashi, H; Tamai, M | 1 |
| Itoh, H; Naito, T; Takeyama, M | 1 |
| Higichi, S; Hirata, W; Ohsawa, T | 1 |
| Kounenis, G; Koutsoviti-Papadopoulou, M; Nikolaidis, E | 1 |
| Gupta, A; Gupta, S; Tiwary, AK | 1 |
| Burdan, F; Dudka, J; Korobowicz, A; Maciejewski, R; Madej, B; Pasternak, M; Radzikowska, E | 1 |
| Stafilov, T; Zendelovska, D | 1 |
| Mozdarani, H | 1 |
| Celik, I; Dietz, W; Duda, D; Junge, A; Lorenz, W; Sauer, S; Sitter, H; Stinner, B | 1 |
| Baroukh, B; Guez, D; Lesclous, P; Saffar, JL; Vignery, A | 1 |
| Endou, H; Hirono, S; Kusuhara, H; Nagata, Y; Sugiyama, Y | 1 |
| Cannon, KE; Fleck, MW; Hough, LB | 1 |
| Hiramoto, K; Inui, K; Motohashi, H; Okuda, M; Uwai, Y | 1 |
| Adachi, K; Azumi, T; Fujisawa, T; Furuta, K; Katsube, T; Kinoshita, Y; Komazawa, Y; Mihara, T | 1 |
| Hishida, A; Ikuma, M; Iwasaki, H; Kajimura, M; Mochizuki, C; Osawa, S; Terakawa, S; Yamamoto, S | 1 |
| Khuder, SA; Quan, WD; Walker, PR | 1 |
| Ahmed, N; Arayne, MS; Sultana, N | 1 |
| Motyl, W | 1 |
| Esplugues, JV; Martí-Cabrera, M; Ponce, J | 1 |
| Arayne, MS; Sana, A; Sultana, N | 1 |
| Arayne, MS; Quraish, R; Sultana, N | 1 |
| Darwish, IA; Hassan, AI; Hussein, SA; Mahmoud, AM | 1 |
| Arayne, MS; Hamza, E; Haroon, U; Sultana, N | 1 |
| Iwatsubo, T; Kamimura, H; Noguchi, K; Umehara, KI | 1 |
| Ashiru, DA; Basit, AW; Patel, R | 1 |
| Daling, JR; Li, CI; Malone, KE; Mathes, RW; Porter, PL | 1 |
| Chen, JZ; Kong, J; Li, ZS; Shi, G; Wang, W; Wu, SD; Zhang, XB | 1 |
| Gorodischer, R; Koren, G; Levy, A; Matok, I; Sheiner, E; Uziel, E; Wiznitzer, A | 1 |
| Chen, Y; Sun, X; Tian, Y; Zhang, Z | 1 |
| Ahmad-Ashrafi, S; Ahmadi, A; Ebrahimzadeh, MA; Karami, M; Mahdavi, MR; Saravi, SS | 1 |
| Amagase, K; Kato, S; Ochi, A; Sugihara, T; Takeuchi, K | 1 |
| Higuchi, K; Murano, M; Tokioka, S; Umegaki, E; Yoda, Y | 1 |
| Arayne, MS; Siddiqui, FA; Sultana, N; Zuberi, MH | 1 |
| Eberlein, B; Gebhardt, E; Gilbertz, KP; Placzek, M; Przybilla, B | 1 |
| Fedorowicz, Z; Hu, N; van Zuuren, EJ | 1 |
| Czimmer, J; Mózsik, G; Szabó, IL; Szolcsányi, J | 1 |
| Ciesielski, A; Jamrógiewicz, M | 1 |
| Bhunia, SS; Saxena, AK; Saxena, M | 1 |
| Ouyang, D; Wan, J; Wang, R; Yin, H; Zheng, Y | 1 |
| Diogo, HP; Moura Ramos, JJ; Viciosa, MT | 1 |
| Ahmed, A; Ali, M; Furqan, H; Hassan, A; Hassan, S; Hussain, K; Iqbal, S; Nazim, U; Shereen, -; Zaheer, E | 1 |
| Keuschler, J; Kržan, M; Mavri, J; Vianello, R | 1 |
| Goto, S; Kasai, T; Komatsu, K; Otsuka, Y; Shimada, Y; Shiono, K; Terada, H | 1 |
| Abdulai, SI; Chandra, S; Ishola, AA; Joshi, T; Pundir, H; Tijjani, H | 1 |
| Hamada, K; Iinuma, F; Matsukubo, H; Matsumoto, T; Miyashita, M; Nishino, K; Okamura, K; Sekiguchi, H; Taga, F | 1 |
| Hirata, Y; Ishii, Y; Yanagisawa, I | 1 |
| Inoue, Y; Ishikawa, H; Katsura, Y; Takasugi, H; Tomishi, T | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Faller, B; Wohnsland, F | 1 |
| Bernhardt, G; Buschauer, A; Elz, S; Kracht, J; Li, L; Peng, S | 1 |
| Kobayashi, Y; Kohyama, N; Ohbayashi, M; Ohshiro, N; Tsuchiya, A; Yamamoto, T | 1 |
| Bakker, RA; Leurs, R; Lim, HD; Ling, P; Thurmond, RL; van Rijn, RM | 1 |
| Chida, M; Fuse, E; Kusuhara, H; Sugiyama, Y; Tahara, H | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Fujiwara, T; Hori, H; Kirk, KL; Miyataka, H; Satoh, T; Shimone, Y; Takeuchi, Y | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| Avdeef, A; Tam, KY | 1 |
| Biagini, GA; Chandramohanadas, R; Darling, C; DeGrado, WF; Diamond, SL; Fisher, N; Greenbaum, DC; Jing, H; Jo, H; Lucumi, E; Napper, AD; Shone, AE; Ward, SA | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Glen, RC; Lowe, R; Mitchell, JB | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Giacomini, KM; Huang, Y; Khuri, N; Kido, Y; Kosaka, A; Morrissey, KM; Sali, A; Wittwer, MB; Zhang, X; Zur, AA | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
29 review(s) available for famotidine and cimetidine
| Article | Year |
|---|---|
Famotidine in gastroesophageal reflux disease (GERD).
Topics: Cimetidine; Esophagitis, Peptic; Famotidine; Gastroesophageal Reflux; Humans; Ranitidine | 1992 |
The clinical use of histamine-2 receptor antagonists.
Topics: Cimetidine; Drug Evaluation; Famotidine; Gastroesophageal Reflux; Humans; Nizatidine; Peptic Ulcer; Ranitidine; Recurrence; Time Factors | 1992 |
[Histamine H2 receptor blockaders: possibilities and prognosis in the use of stage III-IV preparations in the therapy of internal diseases].
Topics: Cimetidine; Famotidine; Gastric Acid; Histamine H2 Antagonists; Humans; Peptic Ulcer; Ranitidine | 1991 |
[Famotidine--a new histamine H2 receptor blockader].
Topics: Cimetidine; Famotidine; Gastric Acid; Gastric Mucosa; Humans; Peptic Ulcer; Receptors, Histamine H2 | 1991 |
Histamine type 2-receptor antagonists and cancer immunotherapy.
Topics: Cimetidine; Clinical Trials as Topic; Famotidine; Histamine H2 Antagonists; Humans; Immunotherapy; Neoplasms; Ranitidine; Suppressor Factors, Immunologic | 1990 |
Clinical review of histamine2 receptor antagonists.
Topics: Cimetidine; Drug Interactions; Duodenal Ulcer; Famotidine; Histamine H2 Antagonists; Humans; Nizatidine; Ranitidine; Stomach Ulcer; Thiazoles | 1990 |
[Gastric acid secretion and histamine H2 receptor antagonists].
Topics: Cimetidine; Famotidine; Gastric Acid; Gastric Mucosa; Histamine H2 Antagonists; Humans; Ranitidine; Receptors, Histamine; Receptors, Histamine H2 | 1990 |
[Gastrin-producing neoformations (Zollinger-Ellison syndrome)].
Topics: Adult; Aged; Child; Cimetidine; Diagnosis, Differential; Famotidine; Gastrectomy; Gastrins; Humans; Middle Aged; Prognosis; Ranitidine; Zollinger-Ellison Syndrome | 1990 |
The current status of the surgical and medical treatment of the Zollinger-Ellison syndrome.
Topics: Anti-Ulcer Agents; Cimetidine; Famotidine; Humans; Prospective Studies; Ranitidine; Zollinger-Ellison Syndrome | 1990 |
[Drugs used in the therapy of peptic ulcer with special reference to H2 receptor blockaders].
Topics: Antacids; Anti-Ulcer Agents; Cimetidine; Famotidine; Female; Histamine H2 Antagonists; Humans; Male; Omeprazole; Peptic Ulcer; Pirenzepine; Ranitidine; Thiazoles | 1989 |
A critical review of continuous infusion H2 receptor therapy.
Topics: Cimetidine; Famotidine; Gastric Juice; Histamine H2 Antagonists; Humans; Hydrogen-Ion Concentration; Infusion Pumps; Infusions, Parenteral; Intensive Care Units; Ranitidine; Thiazoles | 1989 |
Recent advances in the management of gastric acid hypersecretion in patients with Zollinger-Ellison syndrome.
Topics: Cimetidine; Famotidine; Gastric Acid; Histamine H2 Antagonists; Humans; Nizatidine; Omeprazole; Parasympatholytics; Ranitidine; Thiazoles; Zollinger-Ellison Syndrome | 1989 |
Pharmacological management of patients with peptic ulcer disease: prospects for the late 1980's.
Topics: Alprostadil; Antacids; Anti-Ulcer Agents; Cimetidine; Drug Resistance; Enprostil; Famotidine; Histamine H2 Antagonists; Humans; Misoprostol; Omeprazole; Peptic Ulcer; Pirenzepine; Prostaglandins; Prostaglandins E, Synthetic; Ranitidine; Sucralfate; Thiazoles | 1987 |
Famotidine: a notable lack of drug interactions.
Topics: Animals; Cimetidine; Cytochrome P-450 Enzyme System; Drug Interactions; Famotidine; Histamine H2 Antagonists; Humans; In Vitro Techniques; Oxidation-Reduction; Ranitidine; Thiazoles | 1987 |
H2-antagonists and motility of the upper gastrointestinal tract in man.
Topics: Cimetidine; Clinical Trials as Topic; Esophagus; Famotidine; Gastrointestinal Motility; Histamine H2 Antagonists; Humans; Peristalsis; Ranitidine; Thiazoles | 1988 |
Comparison of famotidine with cimetidine and ranitidine.
Topics: Cimetidine; Famotidine; Histamine H2 Antagonists; Humans; Ranitidine; Thiazoles | 1988 |
Pharmacokinetics of histamine (H2)-receptor antagonists, including roxatidine, in chronic renal failure.
Topics: Anti-Ulcer Agents; Cimetidine; Famotidine; Histamine H2 Antagonists; Humans; Kidney Failure, Chronic; Piperidines; Ranitidine; Renal Dialysis; Thiazoles | 1988 |
Do H2 receptor antagonists have a therapeutic role in childhood?
Topics: Adolescent; Child; Child, Preschool; Cimetidine; Cystic Fibrosis; Drug Interactions; Famotidine; Gastroesophageal Reflux; Gastrointestinal Hemorrhage; Humans; Infant; Infant, Newborn; Peptic Ulcer; Pneumonia, Aspiration; Ranitidine; Stress, Physiological | 1994 |
H2-antagonists and alcohol. Do they interact?
Topics: Alcohol Dehydrogenase; Animals; Cimetidine; Drug Interactions; Ethanol; Famotidine; Histamine H2 Antagonists; Humans; Nizatidine; Ranitidine; Rats | 1994 |
Short-term treatment of gastric ulcer. A meta-analytical evaluation of blind trials.
Topics: Antacids; Anti-Ulcer Agents; Bismuth; Cimetidine; Controlled Clinical Trials as Topic; Famotidine; Histamine H2 Antagonists; Humans; Placebos; Ranitidine; Stomach Ulcer; Sucralfate; Time Factors | 1996 |
[H2-receptor antagonists and alcohol: clinical significance].
Topics: Cimetidine; Clinical Medicine; Drug Interactions; Ethanol; Famotidine; Gastric Mucosa; Histamine H2 Antagonists; Humans; Liver; Nizatidine; Piperidines; Ranitidine | 1996 |
Pharmacokinetic optimisation in the treatment of gastro-oesophageal reflux disease.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Antacids; Benzimidazoles; Cimetidine; Cisapride; Domperidone; Famotidine; Gastroesophageal Reflux; Histamine H2 Antagonists; Humans; Lansoprazole; Metoclopramide; Nizatidine; Omeprazole; Pantoprazole; Piperidines; Proton Pump Inhibitors; Ranitidine; Sucralfate; Sulfoxides | 1996 |
Effect of histamine-2 receptor antagonists on blood alcohol levels: a meta-analysis.
Topics: Cimetidine; Ethanol; Famotidine; Histamine H2 Antagonists; Humans; Nizatidine; Ranitidine | 1998 |
H(2) antagonist-induced thrombocytopenia: is this a real phenomenon?
Topics: Cimetidine; Critical Care; Famotidine; Histamine H2 Antagonists; Humans; Peptic Ulcer; Ranitidine; Risk Factors; Thrombocytopenia | 2002 |
Continuous infusion interleukin-2 and antihistamines in metastatic kidney cancer.
Topics: Adjuvants, Immunologic; Antineoplastic Agents; Cimetidine; Famotidine; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Interleukin-2; Kidney Neoplasms; Neoplasm Metastasis; Ranitidine; Time Factors; Treatment Outcome | 2005 |
[Safety of proton pump inhibitors].
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adenosine Triphosphatases; Adult; Age Factors; Aged; Animals; Anti-Ulcer Agents; Cimetidine; Enzyme Inhibitors; Famotidine; Female; Fetus; Histamine H2 Antagonists; Humans; Lactation; Lansoprazole; Meta-Analysis as Topic; Nizatidine; Omeprazole; Pantoprazole; Pregnancy; Proton Pump Inhibitors; Proton-Translocating ATPases; Rabeprazole; Ranitidine; Safety; Time Factors | 2006 |
Histamine H2-receptor antagonists for urticaria.
Topics: Cimetidine; Diphenhydramine; Drug Therapy, Combination; Famotidine; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Randomized Controlled Trials as Topic; Ranitidine; Urticaria | 2012 |
Molecular pharmacological approaches to effects of capsaicinoids and of classical antisecretory drugs on gastric basal acid secretion and on indomethacin-induced gastric mucosal damage in human healthy subjects (mini review).
Topics: Adult; Afferent Pathways; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Atropine; Capsaicin; Cimetidine; Dose-Response Relationship, Drug; Famotidine; Female; Gastric Acid; Gastric Mucosa; Humans; Indomethacin; Male; Omeprazole; Peptic Ulcer; Ranitidine | 2013 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
64 trial(s) available for famotidine and cimetidine
| Article | Year |
|---|---|
Impact of chronic oral H2-antagonist therapy on left ventricular systolic function and exercise capacity.
Topics: Administration, Oral; Adult; Cimetidine; Double-Blind Method; Electrocardiography; Exercise Test; Famotidine; Histamine H2 Antagonists; Humans; Male; Oxygen Consumption; Ranitidine; Systole; Time Factors; Ventricular Function, Left | 1992 |
Ranitidine, cimetidine, famotidine have no effect on post-prandial absorption of ethanol 0.8 g/kg taken after an evening meal.
Topics: Absorption; Adult; Biological Availability; Cimetidine; Dose-Response Relationship, Drug; Double-Blind Method; Drug Interactions; Eating; Ethanol; Famotidine; Histamine H2 Antagonists; Humans; Male; Ranitidine | 1992 |
[Famotidine does not modify the plasma levels of lidocaine for spinal anesthesia. A comparative study of famotidine and cimetidine].
Topics: Aged; Anesthesia, Spinal; Cimetidine; Depression, Chemical; Famotidine; Gastric Acid; Humans; Lidocaine; Male | 1992 |
Effect of H2-blockers, cimetidine and famotidine, on histamine nasal provocative test.
Topics: Adult; Cimetidine; Double-Blind Method; Famotidine; Histamine; Humans; Male; Middle Aged; Nasal Mucosa; Nasal Provocation Tests; Respiratory Hypersensitivity; Sneezing | 1992 |
Morning versus evening dose: a comparison of three H2-receptor blockers in duodenal ulcer healing.
Topics: Adult; Cimetidine; Drug Administration Schedule; Duodenal Ulcer; Famotidine; Humans; Male; Middle Aged; Prospective Studies; Ranitidine; Single-Blind Method | 1992 |
Effects of curative gastrinoma resection on gastric secretory function and antisecretory drug requirement in the Zollinger-Ellison syndrome.
Topics: Adult; Aged; Cimetidine; Dose-Response Relationship, Drug; Duodenal Neoplasms; Famotidine; Female; Follow-Up Studies; Gastric Acid; Gastric Mucosa; Gastrinoma; Gastrins; Humans; Male; Middle Aged; Omeprazole; Pancreatic Neoplasms; Postoperative Period; Prospective Studies; Ranitidine; Sex Factors; Time Factors; Zollinger-Ellison Syndrome | 1992 |
Rebound intragastric hyperacidity after abrupt withdrawal of histamine H2 receptor blockade.
Topics: Adult; Cimetidine; Drug Administration Schedule; Drug Tolerance; Famotidine; Gastric Acid; Gastric Acidity Determination; Gastric Mucosa; Gastrins; Histamine H2 Antagonists; Humans; Male; Nizatidine; Ranitidine; Stomach | 1991 |
[Famotidine--a new histamine H2 receptor blockader].
Topics: Cimetidine; Famotidine; Gastric Acid; Gastric Mucosa; Humans; Peptic Ulcer; Receptors, Histamine H2 | 1991 |
The effect of ranitidine, cimetidine or famotidine on low-dose post-prandial alcohol absorption.
Topics: Adult; Cimetidine; Double-Blind Method; Eating; Ethanol; Famotidine; Humans; Intestinal Absorption; Male; Ranitidine | 1991 |
[Comparison of the efficacy of famotidine and cimetidine in in prophylaxis of Mendelson's syndrome in elective surgery].
Topics: Cimetidine; Famotidine; Female; Humans; Male; Middle Aged; Pneumonia, Aspiration; Postoperative Complications; Syndrome | 1991 |
Histamine type 2-receptor antagonists and cancer immunotherapy.
Topics: Cimetidine; Clinical Trials as Topic; Famotidine; Histamine H2 Antagonists; Humans; Immunotherapy; Neoplasms; Ranitidine; Suppressor Factors, Immunologic | 1990 |
Hemodynamic effects of different H2-receptor antagonists.
Topics: Adult; Cardiac Output; Cardiography, Impedance; Cimetidine; Double-Blind Method; Famotidine; Female; Hemodynamics; Histamine H2 Antagonists; Humans; Male; Random Allocation; Ranitidine; Stroke Volume | 1990 |
Comparative efficacy of cimetidine, famotidine, ranitidine, and mylanta in postoperative stress ulcers. Gastric pH control and ulcer prevention in patients undergoing coronary artery bypass graft surgery.
Topics: Aged; Aluminum Hydroxide; Antacids; Cimetidine; Coronary Artery Bypass; Drug Combinations; Famotidine; Female; Humans; Magnesium Hydroxide; Male; Middle Aged; Peptic Ulcer; Postoperative Complications; Prospective Studies; Ranitidine; Simethicone; Stress, Physiological | 1991 |
Dopamine agonists prevent duodenal ulcer relapse. A comparative study with famotidine and cimetidine.
Topics: Adult; Aged; Amantadine; Bromocriptine; Cimetidine; Duodenal Ulcer; Famotidine; Female; Humans; Male; Middle Aged; Recurrence | 1991 |
Effects of famotidine and cimetidine on plasma levels of epidurally administered lignocaine.
Topics: Anesthesia, Epidural; Cimetidine; Famotidine; Female; Humans; Lidocaine; Male; Middle Aged; Pneumonia, Aspiration; Preanesthetic Medication; Time Factors | 1990 |
Haemodynamic effects of famotidine and cimetidine in critically ill patients.
Topics: Adult; Aged; Cimetidine; Critical Care; Famotidine; Female; Hemodynamics; Humans; Male; Middle Aged | 1990 |
Single night-time doses of 40 mg famotidine or 800 mg cimetidine in the treatment of duodenal ulcer.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aluminum Hydroxide; Antacids; Cimetidine; Double-Blind Method; Drug Combinations; Duodenal Ulcer; Endoscopy, Gastrointestinal; Famotidine; Female; Humans; Magnesium Hydroxide; Male; Middle Aged; Pain; Smoking | 1989 |
A comparison of the influence of famotidine and cimetidine on phenytoin elimination and hepatic blood flow.
Topics: Cimetidine; Cytochrome P-450 Enzyme System; Drug Evaluation; Famotidine; Female; Histamine H2 Antagonists; Humans; Indocyanine Green; Liver Circulation; Male; Phenytoin; Random Allocation; Thiazoles | 1989 |
[Inhibition of 24-hour acidity by nizatidine].
Topics: Cimetidine; Circadian Rhythm; Clinical Trials as Topic; Double-Blind Method; Famotidine; Gastric Acid; Gastric Acidity Determination; Histamine H2 Antagonists; Humans; Nizatidine; Random Allocation; Ranitidine; Thiazoles | 1989 |
A multicenter, randomized, double-blind study comparing famotidine with cimetidine in the treatment of active duodenal ulcer disease.
Topics: Adult; Cimetidine; Double-Blind Method; Drug Administration Schedule; Duodenal Ulcer; Famotidine; Female; Histamine H2 Antagonists; Humans; Male; Multicenter Studies as Topic; Random Allocation; Thiazoles | 1989 |
MK-208, a novel histamine H2-receptor inhibitor with prolonged antisecretory effect.
Topics: Adult; Cimetidine; Famotidine; Gastric Acid; Gastric Juice; Gastric Mucosa; Histamine H2 Antagonists; Humans; Hydrogen-Ion Concentration; Middle Aged; Pentagastrin; Thiazoles | 1985 |
Famotidine, a new H2-receptor antagonist, does not affect hepatic elimination of diazepam or tubular secretion of procainamide.
Topics: Adult; Cimetidine; Diazepam; Famotidine; Histamine H2 Antagonists; Humans; In Vitro Techniques; Kidney Tubules; Kinetics; Liver; Male; Microsomes, Liver; Middle Aged; Procainamide; Random Allocation; Thiazoles | 1985 |
Famotidine in the treatment of gastric and duodenal ulceration: overview of clinical experience.
Topics: Acute Disease; Chronic Disease; Cimetidine; Circadian Rhythm; Clinical Trials as Topic; Double-Blind Method; Drug Administration Schedule; Duodenal Ulcer; Endoscopy; Famotidine; Gefarnate; Histamine H2 Antagonists; Humans; Ranitidine; Stomach Ulcer; Thiazoles; Time Factors | 1985 |
Famotidine in the therapy of gastric hypersecretory states.
Topics: Adult; Aged; Cimetidine; Clinical Trials as Topic; Drug Therapy, Combination; Famotidine; Female; Gastric Acid; Histamine H2 Antagonists; Humans; Longitudinal Studies; Male; Middle Aged; Parasympatholytics; Ranitidine; Thiazoles; Zollinger-Ellison Syndrome | 1986 |
Famotidine: effective treatment of Zollinger-Ellison syndrome.
Topics: Adult; Aged; Cimetidine; Dose-Response Relationship, Drug; Famotidine; Female; Gastric Acid; Histamine H2 Antagonists; Humans; Male; Middle Aged; Ranitidine; Thiazoles; Zollinger-Ellison Syndrome | 1987 |
H2-receptor antagonists and duodenal ulcer recurrence: analysis of efficacy and commentary on safety, costs, and patient selection.
Topics: Cimetidine; Clinical Trials as Topic; Costs and Cost Analysis; Duodenal Ulcer; Famotidine; Histamine H2 Antagonists; Humans; Ranitidine; Recurrence; Risk Factors; Thiazoles; Time Factors | 1987 |
Comparative effect of famotidine and cimetidine on the pharmacokinetics of theophylline in normal volunteers.
Topics: Cimetidine; Famotidine; Female; Histamine H2 Antagonists; Humans; Injections, Intravenous; Male; Theophylline; Thiazoles | 1987 |
Double blind comparison of the effects of cimetidine, ranitidine, famotidine, and placebo on intragastric acidity in 30 normal volunteers.
Topics: Cimetidine; Double-Blind Method; Drug Evaluation; Famotidine; Female; Gastric Acid; Gastric Acidity Determination; Histamine H2 Antagonists; Humans; Male; Ranitidine; Thiazoles; Time Factors | 1988 |
H2-antagonists and motility of the upper gastrointestinal tract in man.
Topics: Cimetidine; Clinical Trials as Topic; Esophagus; Famotidine; Gastrointestinal Motility; Histamine H2 Antagonists; Humans; Peristalsis; Ranitidine; Thiazoles | 1988 |
Effects of H2-receptor antagonists on ethanol metabolism in Japanese volunteers.
Topics: Acetaldehyde; Adult; Cimetidine; Ethanol; Famotidine; Histamine H2 Antagonists; Humans; Japan; Male; Ranitidine; Thiazoles | 1988 |
Famotidine versus cimetidine in the treatment of acute duodenal ulcer. Double-blind, randomized clinical trial comparing nocturnal administration of 40 mg famotidine to 800 mg cimetidine.
Topics: Acute Disease; Adult; Aged; Anti-Ulcer Agents; Cimetidine; Clinical Trials as Topic; Double-Blind Method; Duodenal Ulcer; Famotidine; Female; Humans; Male; Middle Aged; Pain; Random Allocation; Thiazoles | 1988 |
Famotidine effects on theophylline pharmacokinetics in subjects affected by COPD. Comparison with cimetidine and placebo.
Topics: Aged; Cimetidine; Famotidine; Female; Half-Life; Humans; Lung Diseases, Obstructive; Male; Metabolic Clearance Rate; Middle Aged; Theophylline; Thiazoles | 1988 |
Famotidine in the short-term treatment of duodenal ulcer and of concomitant peptic lesions: comparison with cimetidine.
Topics: Cimetidine; Duodenal Ulcer; Famotidine; Female; Humans; Male; Middle Aged; Peptic Ulcer; Thiazoles | 1988 |
Summary of the 30th meeting of the Food and Drug Administration Gastrointestinal Drugs Advisory Committee January 16-17, 1986.
Topics: Aluminum; Cimetidine; Clinical Trials as Topic; Duodenal Ulcer; Famotidine; Humans; Peptic Ulcer; Sucralfate; Thiazoles; United States; United States Food and Drug Administration | 1986 |
Effects of 800 mg cimetidine once daily on gastric acid secretion.
Topics: Administration, Oral; Cimetidine; Circadian Rhythm; Clinical Trials as Topic; Duodenal Ulcer; Famotidine; Gastric Acid; Humans; Ranitidine; Thiazoles | 1986 |
24 hour intragastric acidity and single night-time dose of three H-2-blockers.
Topics: Cimetidine; Clinical Trials as Topic; Double-Blind Method; Famotidine; Gastric Acidity Determination; Histamine H2 Antagonists; Humans; Random Allocation; Ranitidine; Thiazoles | 1983 |
[Comparative study of the effect of famotidine and cimetidine on antipyrine pharmacokinetics in the human].
Topics: Adult; Antipyrine; Cimetidine; Famotidine; Female; Histamine H1 Antagonists; Humans; Kinetics; Male; Thiazoles | 1984 |
Low dose famotidine and cimetidine in single postprandial doses: a placebo controlled comparative study of overnight pH.
Topics: Adult; Anti-Ulcer Agents; Cimetidine; Drug Administration Schedule; Eating; Famotidine; Female; Gastric Acidity Determination; Gastric Juice; Humans; Hydrogen-Ion Concentration; Male | 1995 |
Controlled study of the putative interaction between famotidine and theophylline in patients with chronic obstructive pulmonary disease.
Topics: Adult; Aged; Cimetidine; Cross-Over Studies; Drug Interactions; Famotidine; Female; Humans; Infusions, Intravenous; Lung Diseases, Obstructive; Male; Middle Aged; Theophylline | 1995 |
Pharmacodynamics of bolus famotidine versus infused cimetidine, ranitidine, and famotidine.
Topics: Adult; Cimetidine; Cross-Over Studies; Drug Administration Schedule; Famotidine; Gastric Acidity Determination; Humans; Infusions, Intravenous; Male; Pilot Projects; Ranitidine; Time Factors | 1994 |
Pretreatment H2 receptor antagonists that differ in P450 modulation activity: comparative effects on paclitaxel clearance rates and neutropenia.
Topics: Adult; Aged; Cimetidine; Cross-Over Studies; Cytochrome P-450 Enzyme System; Famotidine; Female; Histamine H2 Antagonists; Humans; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Ovarian Neoplasms; Paclitaxel; Premedication; Prospective Studies | 1995 |
Inhibition of gastric alcohol dehydrogenase activity by histamine H2-receptor antagonists has no influence on the pharmacokinetics of ethanol after a moderate dose.
Topics: Administration, Oral; Adult; Alcohol Dehydrogenase; Analysis of Variance; Cimetidine; Ethanol; Famotidine; Gastric Mucosa; Histamine H2 Antagonists; Humans; Male; Ranitidine | 1994 |
Short report: a comparative study of the interaction between antacid and H2-receptor antagonists.
Topics: Adult; Antacids; Biological Availability; Chromatography, High Pressure Liquid; Cimetidine; Dose-Response Relationship, Drug; Drug Interactions; Famotidine; Histamine H2 Antagonists; Humans; Male; Nizatidine | 1994 |
Changes of resorption and metabolism of cyclosporine after heart transplantation by the influence of gastrointestinal agents.
Topics: Administration, Oral; Aluminum Hydroxide; Animals; Antacids; Anti-Ulcer Agents; Antilymphocyte Serum; Azathioprine; Cimetidine; Cyclosporine; Drug Combinations; Famotidine; Female; Heart Transplantation; Humans; Intestinal Absorption; Magnesium Hydroxide; Male; Middle Aged; Omeprazole; Pirenzepine; Prednisone; Rats; Rats, Inbred BN | 1994 |
Effect of H2-receptor antagonists cimetidine and famotidine on interdigestive gastric motor activity and lower esophageal sphincter pressure in progressive systemic sclerosis.
Topics: Cimetidine; Esophagogastric Junction; Famotidine; Female; Gastrointestinal Motility; Humans; Injections, Intravenous; Male; Middle Aged; Pressure; Scleroderma, Systemic | 1994 |
Lack of effect of H2-receptor antagonists on the pharmacokinetics of alcohol consumed after food at lunchtime.
Topics: Adult; Cimetidine; Drug Interactions; Ethanol; Famotidine; Food; Humans; Male; Ranitidine; Time Factors | 1994 |
Comparative effects of H2-receptor antagonists on subjective and objective assessments of sleep.
Topics: Adult; Cimetidine; Double-Blind Method; Drug Tolerance; Famotidine; Humans; Polysomnography; Ranitidine; Respiration; Sleep | 1994 |
Histamine-2 receptor antagonists do not alter serum ethanol levels in fed, nonalcoholic men.
Topics: Adult; Asian People; Cimetidine; Drug Interactions; Ethanol; Famotidine; Histamine H2 Antagonists; Humans; Male; Nizatidine; Prospective Studies; Ranitidine | 1993 |
Clinical evaluation of the effect of omeprazole, cimetidine, famotidine and ranitidine on histamine induced cutaneous wheal and flare response.
Topics: Adult; Cimetidine; Drug Hypersensitivity; Dyspepsia; Famotidine; Female; Histamine; Histamine H2 Antagonists; Humans; India; Male; Middle Aged; Omeprazole; Ranitidine | 1993 |
Effects of histamine type 2-receptor antagonists cimetidine and famotidine on left ventricular systolic function in chronic congestive heart failure.
Topics: Aged; Analysis of Variance; Chronic Disease; Cimetidine; Double-Blind Method; Echocardiography; Famotidine; Female; Heart Failure; Humans; Male; Middle Aged; Systole; Ventricular Function, Left | 1993 |
The effects of cimetidine, ranitidine and famotidine on the single-dose pharmacokinetics of naproxen and its metabolites in humans.
Topics: Adult; Cimetidine; Drug Interactions; Famotidine; Female; Glucuronates; Humans; Male; Middle Aged; Naproxen; Ranitidine | 1993 |
Ferrous sulfate does not reduce serum levels of famotidine or cimetidine after concurrent ingestion.
Topics: Administration, Oral; Adult; Cimetidine; Cross-Over Studies; Drug Administration Schedule; Famotidine; Female; Ferrous Compounds; Histamine H2 Antagonists; Humans; Male; Time Factors | 1996 |
[The efficacy of using letsedil for treating patients with digestive organ diseases].
Topics: Aluminum Hydroxide; Antacids; Benzilates; Benzocaine; Choline; Cimetidine; Digestive System Diseases; Dose-Response Relationship, Drug; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Famotidine; Histamine H2 Antagonists; Humans; Magnesium Hydroxide; Time Factors | 1996 |
Candida overgrowth after treatment of duodenal ulcer. A comparison of cimetidine, famotidine, and omeprazole.
Topics: Adult; Anti-Ulcer Agents; Candidiasis; Cimetidine; Duodenal Diseases; Duodenal Ulcer; Famotidine; Female; Gastric Acidity Determination; Humans; Male; Omeprazole; Prospective Studies | 1996 |
[The effect of cimetidine and famotidine on esophageal motility].
Topics: Adult; Cimetidine; Duodenal Ulcer; Esophagus; Famotidine; Female; Gastroesophageal Reflux; Histamine H2 Antagonists; Humans; Male; Middle Aged; Pressure | 1996 |
Enhancement of alcohol-induced hypoglycaemia by H2-receptor antagonists.
Topics: Acetaldehyde; Anti-Ulcer Agents; Blood Glucose; Cimetidine; Drug Synergism; Ethanol; Famotidine; Histamine H2 Antagonists; Humans; Hyperglycemia; Lactic Acid; Male; Pyruvic Acid; Ranitidine | 1997 |
Low-dose famotidine and effervescent cimetidine in healthy subjects: a placebo-controlled overnight pH study.
Topics: Adult; Anti-Ulcer Agents; Area Under Curve; Cimetidine; Cross-Over Studies; Famotidine; Female; Gastric Acid; Humans; Hydrogen-Ion Concentration; Male; Pharmaceutical Solutions | 1998 |
The action of 10 mg famotidine versus 200 mg cimetidine: onset and magnitude of antisecretory action within the first 2 hours after administration.
Topics: Administration, Oral; Adult; Anti-Ulcer Agents; Cimetidine; Cross-Over Studies; Drug Monitoring; Famotidine; Female; Gastric Acid; Gastric Acidity Determination; Heartburn; Histamine H2 Antagonists; Humans; Hydrogen-Ion Concentration; Male; Middle Aged; Nonprescription Drugs; Time Factors | 1998 |
[The effect of histamine H2 receptor blockers on reparative processes in the gastric mucosa of patients with gastric peptic ulcer].
Topics: Adult; Antacids; Anti-Ulcer Agents; Autoradiography; Biopsy; Cimetidine; Famotidine; Female; Gastric Mucosa; Histamine H2 Antagonists; Humans; Male; Middle Aged; Stomach Ulcer; Wound Healing | 1999 |
Effects of histamine H(2)-receptor antagonists on human plasma levels of calcitonin gene-related peptide, substance P and vasoactive intestinal peptide.
Topics: Adult; Calcitonin Gene-Related Peptide; Cimetidine; Famotidine; Histamine H2 Antagonists; Humans; Male; Nizatidine; Ranitidine; Substance P; Time Factors; Vasoactive Intestinal Peptide | 2002 |
Comparative study of the speed of acid-suppressing effects of oral administration of cimetidine and famotidine.
Topics: Adult; Chromatography, High Pressure Liquid; Cimetidine; Cross-Over Studies; Famotidine; Follow-Up Studies; Gastric Acid; Gastric Mucosa; Gastroesophageal Reflux; Histamine H2 Antagonists; Humans; Hydrogen-Ion Concentration; Male; Middle Aged; Peptic Ulcer; Reference Values; Stomach | 2005 |
[The effect of H2 receptor blockers on renal function. An attempt to accurately measure glomerular filtration].
Topics: Adolescent; Adult; Aged; Cimetidine; Creatinine; Evaluation Studies as Topic; Famotidine; Female; Glomerular Filtration Rate; Histamine H2 Antagonists; Humans; Kidney Function Tests; Kidney Tubules, Distal; Male; Metabolic Clearance Rate; Middle Aged; Ranitidine; Reference Values | 2004 |
Choledochoscope manometry about different drugs on the Sphincter of Oddi.
Topics: Adult; Aged; Aged, 80 and over; Benzamides; Cholecystectomy; Cimetidine; Domperidone; Endoscopes; Famotidine; Female; Gabexate; Gastrointestinal Agents; Glycoproteins; Histamine H2 Antagonists; Humans; Male; Manometry; Middle Aged; Morpholines; Muscle Contraction; Pressure; Serine Proteinase Inhibitors; Sphincter of Oddi; Young Adult | 2008 |
Molecular pharmacological approaches to effects of capsaicinoids and of classical antisecretory drugs on gastric basal acid secretion and on indomethacin-induced gastric mucosal damage in human healthy subjects (mini review).
Topics: Adult; Afferent Pathways; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Atropine; Capsaicin; Cimetidine; Dose-Response Relationship, Drug; Famotidine; Female; Gastric Acid; Gastric Mucosa; Humans; Indomethacin; Male; Omeprazole; Peptic Ulcer; Ranitidine | 2013 |
225 other study(ies) available for famotidine and cimetidine
| Article | Year |
|---|---|
Structural studies on H2-antagonists: crystal and molecular structure of N-cyano-N'-methyl-N"-(2-[(2-amino-5-thiazolyl)methylthio]ethyl) guanidine and N-cyano-3-[(2-guanidino-5-thiazolyl)methylthio]propionamidine.
Topics: Cimetidine; Crystallization; Famotidine; Guanidines; Histamine H2 Antagonists; Molecular Conformation; Thiazoles; X-Ray Diffraction | 1992 |
Lack of effect of certain histamine H2-receptor blockers on the glucuronidation of 7-hydroxy-4-methylcoumarin by human liver microsomes.
Topics: Cimetidine; Famotidine; Glucuronosyltransferase; Histamine H2 Antagonists; Humans; Hymecromone; Microsomes, Liver; Ranitidine; Uridine Diphosphate Glucuronic Acid | 1992 |
Comparative study of the H2-receptor antagonists cimetidine, ranitidine, famotidine and nizatidine on the rabbit stomach fundus and sigmoid colon.
Topics: Acetylcholine; Animals; Cimetidine; Colon, Sigmoid; Famotidine; Female; Gastric Fundus; Histamine H2 Antagonists; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Nizatidine; Rabbits; Ranitidine | 1992 |
[H2 antagonists as inhibitors of cytochrome P-450 in rat liver: in vitro and in vivo effects].
Topics: Administration, Oral; Aminopyrine; Animals; Biotransformation; Cimetidine; Cytochrome P-450 Enzyme Inhibitors; Enzyme Induction; Famotidine; Hemeproteins; Histamine H2 Antagonists; Male; Methylation; Microsomes, Liver; Mixed Function Oxygenases; Oxidation-Reduction; Ranitidine; Rats; Rats, Wistar; Superoxides | 1992 |
Effects of histamine H2-receptor antagonists and a proton pump inhibitor on the mucosal hydroxyproline content of ethanol-HCl-induced gastric lesions in rats.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adenosine Triphosphatases; Animals; Anti-Ulcer Agents; Benzimidazoles; Cimetidine; Collagen; Ethanol; Famotidine; Gastric Mucosa; Hydrochloric Acid; Hydroxyproline; Male; Omeprazole; Rabeprazole; Rats; Rats, Inbred Strains; Stomach Ulcer | 1992 |
H2-receptor antagonists and blood alcohol levels.
Topics: Administration, Oral; Adult; Biological Availability; Cimetidine; Ethanol; Famotidine; Humans; Male; Ranitidine | 1992 |
Comparative efficacy of cimetidine, famotidine, ranitidine, and mylanta in postoperative stress ulcers.
Topics: Aluminum Hydroxide; Antacids; Cimetidine; Drug Combinations; Famotidine; Humans; Magnesium Hydroxide; Peptic Ulcer; Postoperative Complications; Ranitidine; Simethicone; Stress, Physiological | 1992 |
Cimetidine and ranitidine affect blood-alcohol levels.
Topics: Alcohol Dehydrogenase; Alcohol Drinking; Cimetidine; Drug Evaluation; Famotidine; Humans; Male; Ranitidine | 1992 |
Does H2 receptor antagonist-resistant ulcer exist?--A review based on bioavailability in man.
Topics: Administration, Oral; Adult; Biological Availability; Cimetidine; Drug Tolerance; Famotidine; Half-Life; Humans; Injections, Intravenous; Male; Ranitidine | 1992 |
Effects of H2-receptor antagonists on gastric alcohol dehydrogenase activity.
Topics: Alcohol Dehydrogenase; Animals; Cimetidine; Famotidine; Gastric Mucosa; Histamine H2 Antagonists; Liver; Male; Nizatidine; Ranitidine; Rats; Rats, Inbred Strains | 1991 |
Further evidence for an interaction between alcohol and certain H2-receptor antagonists.
Topics: Adult; Alcoholic Intoxication; Cimetidine; Ethanol; Famotidine; Histamine H2 Antagonists; Humans; Male; Nizatidine; Omeprazole; Ranitidine | 1991 |
Time-dependent interaction of a new H2-receptor antagonist, IT-066, with the receptor in the atria of guinea pig.
Topics: Animals; Binding, Competitive; Cimetidine; Famotidine; Guinea Pigs; Heart Atria; Heart Rate; Histamine H2 Antagonists; Kinetics; Male; Myocardium; Piperidines; Pyridines; Receptors, Histamine H2; Stimulation, Chemical; Time Factors | 1991 |
Characterization of histamine H2-receptors in human neutrophils with a series of guanidine analogues of impromidine. Are cell type-specific H2-receptors involved in the regulation of NADPH oxidase?
Topics: 1-Methyl-3-isobutylxanthine; Cardiotonic Agents; Cimetidine; Dose-Response Relationship, Drug; Famotidine; Guanidines; Humans; Imidazoles; Impromidine; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Receptors, Histamine H2; Superoxides | 1990 |
Mechanism of action of H2-antagonists on histamine- or dimaprit-stimulated H2-receptors of spontaneously beating guinea-pig atrium.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Cimetidine; Dimaprit; Famotidine; Female; Guinea Pigs; Heart; Histamine; Histamine H2 Antagonists; In Vitro Techniques; Radioligand Assay; Ranitidine; Receptors, Histamine H2; Thiourea | 1990 |
Cell proliferation kinetics in the marginal mucosa of gastric ulcer evaluated by immunostaining of DNA polymerase alpha.
Topics: Adult; Aged; Antibodies, Monoclonal; Cell Division; Cimetidine; DNA Polymerase II; Famotidine; Female; Gastric Mucosa; Humans; Kinetics; Male; Middle Aged; Ranitidine; Staining and Labeling; Stomach Ulcer | 1991 |
Effects of ranitidine on blood alcohol levels after ethanol ingestion. Comparison with other H2-receptor antagonists.
Topics: Adult; Biological Availability; Cimetidine; Ethanol; Famotidine; Humans; Male; Middle Aged; Ranitidine | 1992 |
[Adsorption of other drugs by hemodialysis membrane].
Topics: Adsorption; Amikacin; Ceftizoxime; Cimetidine; Famotidine; Humans; Kidney Failure, Chronic; Membranes, Artificial; Porosity; Protein Binding; Renal Dialysis; Rifampin | 1991 |
H2-receptor antagonists and acute intermittent porphyria.
Topics: Acute Disease; Cimetidine; Drug Evaluation; Famotidine; Humans; Porphyrias; Ranitidine; Skin Diseases | 1991 |
Definition for idiopathic gastric acid hypersecretion. A statistical and functional evaluation.
Topics: Adult; Cimetidine; Duodenal Ulcer; Famotidine; Female; Gastric Acid; Humans; Male; Middle Aged; Ranitidine; Reference Values | 1991 |
H2-receptor antagonism by a novel compound IT-066 assessed from [14C]aminopyrine accumulation in rabbit parietal cells.
Topics: Aminopyrine; Animals; Anti-Ulcer Agents; Bucladesine; Carbachol; Cimetidine; Famotidine; Gastric Mucosa; Histamine; Histamine H2 Antagonists; In Vitro Techniques; Male; Piperidines; Pyridines; Rabbits | 1990 |
The histological maturity of regenerating mucosa of healed duodenal ulcer and ulcer recurrence after treatment with H2-antagonist.
Topics: Adolescent; Adult; Aged; Cimetidine; Duodenal Ulcer; Duodenoscopy; Famotidine; Female; Histamine H2 Antagonists; Humans; Intestinal Mucosa; Male; Middle Aged; Recurrence; Regeneration; Time Factors | 1990 |
[Cyclosporin (CyA) and H2 antagonists].
Topics: Animals; Cimetidine; Cyclosporins; Drug Interactions; Famotidine; Fatty Liver; Histamine H2 Antagonists; Liver; Ranitidine; Rats; Rats, Inbred Strains; Time Factors | 1990 |
[Effect of teprenone and H2-receptor antagonists on phosphatidylcholine synthesis in the isolated guinea pig gastric glands].
Topics: Animals; Anti-Ulcer Agents; Choline-Phosphate Cytidylyltransferase; Cimetidine; Diterpenes; Famotidine; Gastric Mucosa; Guinea Pigs; Histamine H2 Antagonists; In Vitro Techniques; Male; Nucleotidyltransferases; Phosphatidylcholines; Ranitidine | 1990 |
Antisecretory and antilesional effect of a new histamine H2-receptor antagonist, IT-066, in rats.
Topics: Animals; Cimetidine; Cold Temperature; Cysteamine; Dose-Response Relationship, Drug; Duodenal Neoplasms; Famotidine; Gastric Acid; Gastric Mucosa; Histamine H2 Antagonists; Indomethacin; Male; Perfusion; Piperidines; Pyridines; Rats; Rats, Inbred Strains; Stomach Neoplasms | 1990 |
Selective and competitive histamine H2-receptor blocking effect of famotidine on the blood pressure response in dogs and the acid secretory response in rats.
Topics: Anesthesia; Animals; Blood Pressure; Cimetidine; Dimaprit; Dogs; Famotidine; Female; Gastric Acid; Histamine H2 Antagonists; Male; Rats; Rats, Inbred Strains; Thiourea | 1990 |
Human gastric alcohol dehydrogenase: its inhibition by H2-receptor antagonists, and its effect on the bioavailability of ethanol.
Topics: Alcohol Dehydrogenase; Biological Availability; Cimetidine; Dose-Response Relationship, Drug; Ethanol; Famotidine; Gastric Mucosa; Histamine H2 Antagonists; Humans; Isoenzymes; Ranitidine | 1990 |
Effects of FRG-8701 on gastric acid secretion, gastric mucosal lesions by necrotizing agents and experimental gastric or duodenal ulcer in rats.
Topics: Acetamides; Animals; Cimetidine; Duodenal Ulcer; Famotidine; Gastric Acid; Gastric Mucosa; Guinea Pigs; Heart Atria; Heart Rate; Histamine H2 Antagonists; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Piperidines; Pylorus; Rats; Rats, Inbred Strains; Stomach Ulcer | 1990 |
Tolerance during 29 days of conventional dosing with cimetidine, nizatidine, famotidine or ranitidine.
Topics: Adult; Cimetidine; Drug Tolerance; Famotidine; Gastric Acid; Gastrins; Histamine H2 Antagonists; Humans; Hydrogen-Ion Concentration; Male; Nizatidine; Ranitidine | 1990 |
Studies on the mechanism for the gastric mucosal protection by famotidine in rats.
Topics: Animals; Anti-Ulcer Agents; Cimetidine; Famotidine; Gastric Mucosa; Male; Pirenzepine; Rats; Rats, Inbred Strains; Regional Blood Flow; Stomach Ulcer; Tranexamic Acid | 1991 |
Cardiovascular and bronchial actions of famotidine in anesthetized dogs.
Topics: Airway Resistance; Anesthesia; Animals; Bronchi; Cimetidine; Dogs; Electrocardiography; Famotidine; Female; Halothane; Heart; Hemodynamics; Histamine; Male; Nitrous Oxide; Pentobarbital; Propranolol | 1990 |
Implementing therapeutic interchange of intravenous famotidine for cimetidine and ranitidine.
Topics: Cimetidine; Cost Control; Drug Prescriptions; Famotidine; Florida; Hospital Bed Capacity, 100 to 299; Humans; Parenteral Nutrition, Total; Pharmacy Service, Hospital; Ranitidine; Therapeutic Equivalency | 1990 |
Evidence of anti-oxidant role of sucralfate in gastric mucosal protection.
Topics: Alum Compounds; Animals; Antioxidants; Cimetidine; Enprostil; Famotidine; Female; Free Radicals; Gastric Mucosa; Glycosaminoglycans; Hydrogen Peroxide; Hydroxides; Male; Misoprostol; Necrosis; Ranitidine; Rats; Rats, Inbred Strains; Sucralfate | 1990 |
Continuous infusion H2-receptor therapy.
Topics: Cimetidine; Famotidine; Gastrointestinal Hemorrhage; Humans; Research | 1990 |
Do the H2-receptor antagonists, cimetidine and famotidine, modify the degree of renal recovery following renal insult?
Topics: Acute Kidney Injury; Animals; Cimetidine; Constriction; Famotidine; Gentamicins; Kidney; Male; Rats; Renal Artery | 1990 |
High doses of ranitidine in maintenance therapy of duodenal ulcer patients.
Topics: Cimetidine; Duodenal Ulcer; Famotidine; Humans; Ranitidine; Recurrence; Smoking | 1990 |
Biotransformation of lovastatin--III. Effect of cimetidine and famotidine on in vitro metabolism of lovastatin by rat and human liver microsomes.
Topics: Animals; Biotransformation; Cimetidine; Cytochrome P-450 Enzyme System; Famotidine; Female; Humans; Lovastatin; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Rats; Rats, Inbred Strains | 1990 |
Effect of an endogenous satiety substance, 2-buten-4-olide, on gastric acid secretion and experimental ulceration in rats.
Topics: 4-Butyrolactone; Animals; Cimetidine; Cysteamine; Deoxyglucose; Duodenal Ulcer; Famotidine; Furans; Gastric Acid; Male; Rats; Rats, Inbred Strains; Stimulation, Chemical; Stomach Ulcer; Stress, Physiological | 1990 |
Famotidine and ranitidine, but not cimetidine, cause severe, disabling headache.
Topics: Adult; Cimetidine; Famotidine; Female; Headache; Histamine H2 Antagonists; Humans; Ranitidine; Thiazoles | 1989 |
Effect of cimetidine, ranitidine, famotidine and omeprazole on hepatocyte proliferation in vitro.
Topics: Animals; Cell Division; Cells, Cultured; Cimetidine; DNA; Famotidine; Hepatectomy; Histamine H2 Antagonists; Hormones; Liver; Omeprazole; Osmolar Concentration; Ranitidine; Rats; Rats, Inbred F344; Thiazoles | 1989 |
Neuronal histamine modulates feeding behavior through H1-receptor in rat hypothalamus.
Topics: Animals; Chlorpheniramine; Cimetidine; Drinking Behavior; Famotidine; Feeding Behavior; Histamine; Histamine H2 Antagonists; Hypothalamus; Injections, Intraventricular; Male; Motor Activity; Neurons; Promethazine; Pyrilamine; Rats; Rats, Inbred Strains; Receptors, Histamine H1; Reference Values; Thiazoles | 1989 |
Safety profile of H2-receptor antagonists: current status of famotidine.
Topics: Anti-Ulcer Agents; Cimetidine; Drug Interactions; Famotidine; Histamine H2 Antagonists; Humans; Ranitidine; Thiazoles | 1989 |
The effects of cimetidine, ranitidine and famotidine on rat hepatic microsomal cytochrome P-450 activities.
Topics: Animals; Binding Sites; Cimetidine; Cytochrome P-450 Enzyme System; Famotidine; Histamine H2 Antagonists; In Vitro Techniques; Male; Microsomes, Liver; Ranitidine; Rats; Rats, Inbred Strains; Thiazoles | 1989 |
Frequent non-response to histamine H2-receptor antagonists in cirrhotics.
Topics: Anti-Ulcer Agents; Cimetidine; Esophagitis, Peptic; Famotidine; Female; Gastric Acidity Determination; Gastritis; Histamine H2 Antagonists; Humans; Liver Cirrhosis; Male; Middle Aged; Peptic Ulcer; Ranitidine; Thiazoles | 1989 |
Evidence of drug interaction between cyclosporin A and H2-receptor antagonists (cimetidine, ranitidine and famotidine) in Sprague-Dawley rats.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Cimetidine; Creatinine; Cyclosporins; Drug Interactions; Famotidine; Histamine H2 Antagonists; Kidney; Liver; Male; Ranitidine; Rats; Rats, Inbred Strains; Thiazoles | 1989 |
Effects of famotidine, a new histamine H2-receptor antagonist, on renal function.
Topics: Acetylglucosaminidase; Adult; Aged; beta 2-Microglobulin; Blood Urea Nitrogen; Cimetidine; Creatinine; Famotidine; Female; Histamine H2 Antagonists; Humans; Kidney; Kidney Diseases; Male; Metabolic Clearance Rate; Middle Aged | 1989 |
A comparison of the cholinergic activity of selected H2-antagonists and sulfoxide metabolites.
Topics: Acetylcholine; Animals; Brain Chemistry; Cholinesterase Inhibitors; Cimetidine; Famotidine; Furans; Histamine H2 Antagonists; Ileum; Male; Mice; Nizatidine; Parasympathomimetics; Ranitidine; Structure-Activity Relationship; Sulfoxides; Thiazoles | 1989 |
Effects of famotidine at the mouse neuromuscular junction compared with those of cimetidine and ranitidine.
Topics: Animals; Cimetidine; Evoked Potentials; Famotidine; Mice; Motor Endplate; Neuromuscular Junction; Ranitidine; Synapses | 1989 |
Differential effects of cimetidine, ranitidine and famotidine on the hepatic metabolism of estrogen and testosterone in male rats.
Topics: Animals; Cimetidine; Estrogens; Famotidine; Liver; Male; Ranitidine; Rats; Rats, Inbred Strains; Testosterone; Thiazoles | 1989 |
Famotidine, a new, potent, long-acting histamine H2-receptor antagonist: comparison with cimetidine and ranitidine in the treatment of Zollinger-Ellison syndrome.
Topics: Aged; Cimetidine; Delayed-Action Preparations; Famotidine; Histamine H2 Antagonists; Humans; Middle Aged; Ranitidine; Thiazoles; Zollinger-Ellison Syndrome | 1985 |
Famotidine, a new H2-receptor antagonist. Effect on parietal, nonparietal, and pepsin secretion in man.
Topics: Adult; Cimetidine; Famotidine; Gastric Acidity Determination; Gastric Juice; Histamine H2 Antagonists; Humans; Male; Parietal Cells, Gastric; Pentagastrin; Pepsin A; Thiazoles; Time Factors | 1985 |
Effects of H2-receptor antagonists upon physiological acid secretory states in animals.
Topics: Animals; Benzimidazoles; Cimetidine; Famotidine; Gastric Emptying; Gastric Juice; Histamine H2 Antagonists; Male; Omeprazole; Rats; Secretory Rate; Thiadiazoles; Thiazoles | 1985 |
Clinical pharmacology of famotidine.
Topics: Animals; Cimetidine; Circadian Rhythm; Dogs; Dose-Response Relationship, Drug; Duodenal Ulcer; Famotidine; Food; Gastric Acid; Half-Life; Histamine; Histamine H2 Antagonists; Humans; Kinetics; Pentagastrin; Pepsin A; Prolactin; Rats; Tetragastrin; Thiazoles; Time Factors | 1985 |
Comparative effects of famotidine and cimetidine on trimethadione metabolism in the rat.
Topics: Animals; Cimetidine; Famotidine; Histamine H2 Antagonists; Kinetics; Male; Microsomes, Liver; Mixed Function Oxygenases; Oxazoles; Rats; Thiazoles; Trimethadione | 1986 |
Interaction of diazepam with famotidine and cimetidine, two H2-receptor antagonists.
Topics: Adult; Biotransformation; Cimetidine; Diazepam; Drug Interactions; Famotidine; Half-Life; Histamine H2 Antagonists; Humans; Infusions, Parenteral; Kinetics; Male; Metabolic Clearance Rate; Middle Aged; Nordazepam; Thiazoles | 1986 |
Cholinergic effects of histamine-H2 receptor antagonists partly through inhibition of acetylcholinesterase.
Topics: Animals; Butyrylcholinesterase; Cholinesterase Inhibitors; Cimetidine; Famotidine; Guinea Pigs; Histamine H2 Antagonists; Humans; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Piperidines; Ranitidine; Thiazoles | 1986 |
Interaction of famotidine with rat liver microsomes, a study showing less inhibition of drug metabolism than with cimetidine.
Topics: Aminopyrine N-Demethylase; Animals; Cimetidine; Cytochrome P-450 Enzyme System; Famotidine; Histamine H2 Antagonists; In Vitro Techniques; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Rats; Rats, Inbred Strains; Thiazoles | 1986 |
Effect of five structurally diverse H2-receptor antagonists on drug metabolism.
Topics: 7-Alkoxycoumarin O-Dealkylase; Animals; Aryl Hydrocarbon Hydroxylases; Biotransformation; Cimetidine; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Diazepam; Famotidine; Histamine H2 Antagonists; Humans; Imidazoles; Kinetics; Male; Microsomes, Liver; Nizatidine; Oxidoreductases; Oxygenases; Pharmaceutical Preparations; Ranitidine; Rats; Rats, Inbred Strains; Thiazoles | 1986 |
Direct effects of H2-receptor antagonists on airway smooth muscle and on responses mediated by H1- and H2-receptors.
Topics: Animals; Cimetidine; Famotidine; Guinea Pigs; Histamine H2 Antagonists; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Ranitidine; Thiazoles; Trachea | 1987 |
[Comparative studies on hemodynamic effects of intravenous cimetidine, ranitidine and famotidine in intensive care unit patients].
Topics: Adult; Aged; Aged, 80 and over; Cimetidine; Famotidine; Female; Hemodynamics; Histamine H2 Antagonists; Humans; Injections, Intravenous; Intensive Care Units; Male; Middle Aged; Ranitidine; Thiazoles | 1987 |
Effect of histamine H2-receptor antagonists on DNA synthesis in adult rat hepatocytes in primary culture. Cimetidine enhanced hepatocytes proliferation stimulated with insulin and epidermal growth factor.
Topics: Animals; Cell Division; Cimetidine; DNA; Epidermal Growth Factor; Famotidine; Histamine H2 Antagonists; Humans; Insulin; Liver; Protein Biosynthesis; Ranitidine; Rats; Thiazoles | 1987 |
[Action of famotidine, a new H2-receptor antagonist, on the papillary muscle and atrium of the guinea pig, in vitro].
Topics: Animals; Cimetidine; Famotidine; Guinea Pigs; Heart Rate; Histamine H2 Antagonists; Imidazoles; In Vitro Techniques; Myocardial Contraction; Ranitidine; Thiazoles | 1987 |
Effects of prolonged oral cimetidine, ranitidine, and famotidine therapy on antipyrine elimination.
Topics: Administration, Oral; Adolescent; Adult; Aged; Antipyrine; Cimetidine; Famotidine; Female; Histamine H2 Antagonists; Humans; Liver; Male; Metabolic Clearance Rate; Middle Aged; Ranitidine; Thiazoles | 1987 |
A comparative evaluation of the transport of H2-receptor antagonists by the human and baboon placenta.
Topics: Adolescent; Adult; Animals; Antipyrine; Biological Transport; Cimetidine; Famotidine; Female; Histamine H2 Antagonists; Humans; In Vitro Techniques; Maternal-Fetal Exchange; Nizatidine; Papio; Perfusion; Placenta; Pregnancy; Ranitidine; Thiazoles | 1988 |
Effect of mifentidine on mepirizole-induced duodenal ulcer in the rat.
Topics: Animals; Anti-Ulcer Agents; Cimetidine; Dose-Response Relationship, Drug; Duodenal Ulcer; Duodenum; Epirizole; Famotidine; Female; Histamine H2 Antagonists; Imidazoles; Intestinal Mucosa; Pyrazoles; Ranitidine; Rats; Rats, Inbred Strains; Thiazoles | 1987 |
The effect of H2-receptor antagonists on antipyrine and pentobarbital metabolism in male and female rats.
Topics: Animals; Antipyrine; Cimetidine; Famotidine; Female; Histamine H2 Antagonists; Male; Microsomes, Liver; Mixed Function Oxygenases; Pentobarbital; Ranitidine; Rats; Rats, Inbred Strains; Sex Factors; Thiazoles | 1988 |
In vitro studies on the interaction of famotidine with liver microsomal cytochrome P-450.
Topics: Animals; Cimetidine; Cytochrome P-450 Enzyme System; Famotidine; Histamine H2 Antagonists; Humans; Male; Methylcholanthrene; Microsomes, Liver; Oxidation-Reduction; Phenobarbital; Rats; Rats, Inbred Strains; Spectrum Analysis; Thiadiazoles; Thiazoles | 1988 |
Differential inhibition of human liver phenacetin O-deethylation by histamine and four histamine H2-receptor antagonists.
Topics: Binding Sites; Binding, Competitive; Catalysis; Chromatography, Thin Layer; Cimetidine; Cytochrome P-450 CYP1A2; Famotidine; Histamine; Histamine H2 Antagonists; Humans; Imidazoles; Microsomes, Liver; Oxidation-Reduction; Oxidoreductases; Ranitidine; Thiazoles | 1988 |
Recurrent parotitis with H2 receptor antagonists in a patient with Sjogren's syndrome.
Topics: Cimetidine; Famotidine; Female; Histamine H2 Antagonists; Humans; Middle Aged; Parotitis; Ranitidine; Recurrence; Sjogren's Syndrome; Stomach Ulcer; Thiazoles | 1988 |
Cimetidine (but not ranitidine or famotidine) affects histamine determination.
Topics: Cimetidine; Famotidine; Histamine; Histamine H2 Antagonists; Humans; Ranitidine; Thiazoles | 1988 |
Plasma sex steroid transport and histamine H2-receptor antagonists. Clinical implications.
Topics: Adult; Cimetidine; Famotidine; Gonadal Steroid Hormones; Histamine H2 Antagonists; Hormones; Humans; Male; Middle Aged; Peptic Ulcer; Ranitidine; Sex Hormone-Binding Globulin; Thiazoles; Thyroid Hormones | 1988 |
Further evidence that brain histamine H2 receptors are stimulatory in the control of prolactin in the rat.
Topics: Animals; Brain; Cimetidine; Dimaprit; Famotidine; Histamine H2 Antagonists; Injections, Intraventricular; Male; Methylhistamines; Prolactin; Ranitidine; Rats; Rats, Inbred Strains; Receptors, Histamine H2; Thiazoles; Thiourea | 1988 |
Bacterial genotoxicity of nitrosated famotidine.
Topics: Animals; Biotransformation; Cimetidine; Escherichia coli; Famotidine; Histamine H1 Antagonists; Microsomes, Liver; Mutagenicity Tests; Mutation; Nitrites; Ranitidine; Rats; Rats, Inbred Strains; Salmonella typhimurium; Thiazoles | 1986 |
Refractory duodenal ulcers (nonhealing duodenal ulcers with standard doses of antisecretory medication).
Topics: Adult; Aged; Anti-Ulcer Agents; Cimetidine; Duodenal Ulcer; Famotidine; Female; Gastric Acid; Humans; Male; Middle Aged; Ranitidine; Smoking; Thiazoles | 1989 |
A comparison of the effects of treatment with either famotidine 40 mg or cimetidine 800 mg nocte on gastric acid secretion and serum gastrin.
Topics: Adult; Cimetidine; Famotidine; Female; Gastric Acid; Gastrins; Humans; Male; Middle Aged | 1988 |
New H2-blockers: does more choice help?
Topics: Anti-Ulcer Agents; Cimetidine; Famotidine; Humans; Nizatidine; Peptic Ulcer; Ranitidine; Thiazoles | 1988 |
Healing and relapse rates of duodenal ulcer with various H2 receptor antagonists.
Topics: Adolescent; Adult; Anti-Ulcer Agents; Cimetidine; Duodenal Ulcer; Famotidine; Female; Humans; Male; Ranitidine; Retrospective Studies; Thiazoles | 1988 |
Comparative effects of famotidine and cimetidine on 7-ethoxycoumarin O-deethylase activity in human livers.
Topics: 7-Alkoxycoumarin O-Dealkylase; Cimetidine; Famotidine; Humans; Liver; Oxygenases; Thiazoles | 1986 |
Comparison of the effects of gastric antisecretory agents in healthy volunteers and patients with duodenal ulcer.
Topics: Anti-Ulcer Agents; Cimetidine; Drug Administration Schedule; Duodenal Ulcer; Famotidine; Gastric Acidity Determination; Humans; Imidazoles; Omeprazole; Ranitidine; Thiazoles | 1986 |
Effect of H2-receptor antagonists on acetaminophen-induced hepatic injury.
Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Cimetidine; Famotidine; Glutathione; Liver; Liver Diseases; Male; Methylcholanthrene; Microsomes, Liver; Ranitidine; Rats; Thiazoles | 1986 |
[H2 receptor antagonists and intragastric acidity].
Topics: Cimetidine; Drug Administration Schedule; Famotidine; Histamine Antagonists; Histamine H2 Antagonists; Humans; Imidazoles; Peptic Ulcer; Ranitidine; Thiazoles | 1984 |
Effect of a new potent H2-blocker, 3-]]]2-[(diaminomethylene)amino]-4-thiazolyl]methyl]-thio]-N2-sulfamoylpropionamidine (YM-11170) on gastric secretion induced by histamine and food in conscious dogs.
Topics: Animals; Cimetidine; Dogs; Famotidine; Food; Gastric Acid; Histamine; Histamine H2 Antagonists; Thiazoles | 1982 |
Effect of a new potent H2-blocker, 3-[[[2-(diaminomethylene)amino]-4-thiazolyl]methyl]thio]-N2-sulfamoyl propionamidine (YM-11170), on gastric secretion, ulcer formation and weight of male accessory sex organs in rats.
Topics: Androgen Antagonists; Animals; Aspirin; Castration; Cimetidine; Famotidine; Gastric Juice; Gastric Mucosa; Genitalia, Male; Histamine H2 Antagonists; Male; Organ Size; Rats; Rats, Inbred Strains; Stomach Ulcer; Testosterone; Thiazoles | 1982 |
Effect of a new potent H2-receptor antagonist 3[[[2-[(diaminomethylene)amino]-4-thiazolyl]methyl]thio]-N2- sulfamoylpropionamidine (YM-11170) on gastric mucosal histamine-sensitive adenylate cyclase from guinea pig.
Topics: Adenylyl Cyclases; Animals; Cimetidine; Dinoprostone; Dose-Response Relationship, Drug; Famotidine; Gastric Mucosa; Guinea Pigs; Hippocampus; Histamine; Histamine H2 Antagonists; Male; Prostaglandins E; Thiazoles | 1983 |
Effects of antiulcer agents on healing of mepirizole-induced duodenal ulcers in rats.
Topics: Aluminum Hydroxide; Animals; Anti-Ulcer Agents; Cimetidine; Drug Combinations; Duodenal Ulcer; Epirizole; Famotidine; Histamine H2 Antagonists; Magnesium Hydroxide; Male; Propantheline; Prostaglandins E, Synthetic; Pyrazoles; Rats; Rats, Inbred Strains; Thiazoles; Time Factors; Wound Healing | 1983 |
Kinetics of antisecretory action of a new H2-antagonist, YM-11170, in conscious dogs.
Topics: Animals; Atropine; Cimetidine; Dimaprit; Dogs; Famotidine; Gastric Acid; Gastric Mucosa; Histamine H2 Antagonists; Kinetics; Male; Methacholine Chloride; Methacholine Compounds; Pentagastrin; Thiazoles; Thiourea | 1983 |
Studies on MK-208 (YM-11170) a new, slowly dissociable H2-receptor antagonist.
Topics: Animals; Cimetidine; Famotidine; Female; Gastric Acid; Gastric Fistula; Guinea Pigs; Heart Atria; Heart Rate; Histamine H2 Antagonists; In Vitro Techniques; Male; Ranitidine; Rats; Thiazoles | 1983 |
Method for detection of antibody against low molecular weight antigen (hapten)--production and detection of antibody against histamine H2 receptor of antibody against histamine H2 receptor antagonist "Famotidine".
Topics: Animals; Antibodies; Antibody Formation; Antibody Specificity; Cimetidine; Famotidine; Fluorescent Antibody Technique; Haptens; Histamine H2 Antagonists; Molecular Weight; Rabbits; Ranitidine; Thiazoles | 1983 |
Inhibition of gastric secretion by a new H2-antagonist, YM-11170 in healthy subjects.
Topics: Administration, Oral; Adult; Cimetidine; Dose-Response Relationship, Drug; Famotidine; Gastric Acid; Gastric Juice; Humans; Male; Pepsin A; Ranitidine; Thiazoles; Time Factors | 1984 |
Effect of H2-receptor antagonists, cimetidine and YM-11170, on serum gastrin levels in lumen-perfused rats.
Topics: Animals; Cimetidine; Famotidine; Gastric Acid; Gastric Acidity Determination; Gastric Mucosa; Gastrins; Histamine; Infusions, Parenteral; Male; Perfusion; Rats; Rats, Inbred Strains; Thiazoles | 1983 |
[Effects of protective agents on ulcer formation].
Topics: Adult; Animals; Cimetidine; Dogs; Duodenal Ulcer; Famotidine; Gastric Juice; Gastric Mucosa; Humans; Male; Peptic Ulcer; Stomach Ulcer; Thiazoles | 1984 |
Comparative effects of famotidine and cimetidine on antipyrine kinetics in healthy volunteers.
Topics: Adult; Antipyrine; Cimetidine; Famotidine; Female; Humans; Kinetics; Male; Thiazoles | 1984 |
Nizatidine accelerates gastric emptying of a solid meal in rats.
Topics: Acetylcholine; Animals; Cimetidine; Dose-Response Relationship, Drug; Famotidine; Gastric Emptying; Gastric Juice; Gastrins; Histamine H2 Antagonists; Male; Nizatidine; Rats; Rats, Wistar; Stimulation, Chemical | 1995 |
Stability and compatibility of anakinra with intravenous cimetidine hydrochloride or famotidine in 0.9% sodium chloride injection.
Topics: Chromatography, High Pressure Liquid; Cimetidine; Drug Combinations; Drug Interactions; Drug Stability; Famotidine; Hydrogen-Ion Concentration; Interleukin 1 Receptor Antagonist Protein; Light; Recombinant Proteins; Sialoglycoproteins; Sodium Chloride; Temperature | 1995 |
Rx-to-OTC switches: two H2 antagonists.
Topics: Cimetidine; Famotidine; Humans; Nonprescription Drugs; Patient Education as Topic | 1995 |
Cimetidine inhibition of human gastric and liver alcohol dehydrogenase isoenzymes: identification of inhibitor complexes by kinetics and molecular modeling.
Topics: Alcohol Dehydrogenase; Binding, Competitive; Cimetidine; Famotidine; Gastric Mucosa; Humans; Isoenzymes; Kinetics; Liver; Mathematics; Models, Molecular; NAD; Nizatidine; Ranitidine; Recombinant Proteins; Structure-Activity Relationship | 1995 |
The effect of three H2-receptor antagonists on the disposition of midazolam in the rat in-situ perfused liver model.
Topics: Animals; Bile; Chromatography, Gas; Cimetidine; Cytochrome P-450 Enzyme System; Drug Interactions; Famotidine; Histamine H2 Antagonists; Liver; Male; Midazolam; Perfusion; Ranitidine; Rats; Rats, Sprague-Dawley | 1994 |
Comparison of immunomodulative effects of the histamine-2 receptor antagonists cimetidine, ranitidine, and famotidine on peripheral blood mononuclear cells in gastric cancer patients.
Topics: Adjuvants, Immunologic; Case-Control Studies; Cimetidine; Cytotoxicity Tests, Immunologic; Famotidine; Female; Humans; In Vitro Techniques; Killer Cells, Natural; Leukocytes, Mononuclear; Lymphocyte Activation; Male; Middle Aged; Ranitidine; Receptors, Interleukin-2; Stomach Neoplasms | 1995 |
[Effects of FRG-8813, a new histamine H2-receptor antagonist, on gastric mucus in rats].
Topics: Acetamides; Administration, Oral; Animals; Cimetidine; Dose-Response Relationship, Drug; Famotidine; Gastric Mucosa; Hexoses; Histamine H2 Antagonists; Male; Mucus; Piperidines; Pyridines; Rats; Rats, Sprague-Dawley | 1994 |
Drug interactions of H2-receptor antagonists.
Topics: Adolescent; Adult; Aged; Antacids; Biological Availability; Cimetidine; Drug Interactions; Famotidine; Histamine H2 Antagonists; Humans; Middle Aged; Nizatidine; Omeprazole; Phenytoin; Ranitidine; Theophylline | 1994 |
Regulation of K+ conductance by histamine H1 and H2 receptors in neurones dissociated from rat neostriatum.
Topics: Animals; Cimetidine; Dose-Response Relationship, Drug; Famotidine; Female; Histamine; Histamine Agonists; Impromidine; In Vitro Techniques; Ion Transport; Male; Membrane Potentials; Methylhistamines; Neostriatum; Potassium; Potassium Channels; Pyrilamine; Ranitidine; Rats; Rats, Wistar; Receptors, Histamine H1; Receptors, Histamine H2; Thiazoles; Triprolidine | 1994 |
Antisecretory effects of a novel and long-lasting histamine H2-receptor antagonist, YM-14471, in rats and dogs.
Topics: Animals; Cimetidine; Dogs; Dose-Response Relationship, Drug; Famotidine; Gastric Acid; Guinea Pigs; Heart Atria; Heart Rate; Histamine; Histamine H2 Antagonists; Infusions, Intravenous; Male; Omeprazole; Pyrimidinones; Rats; Rats, Wistar; Thiazoles | 1993 |
[Effects of various histamine H2-receptor antagonists on gastrointestinal motility and gastric emptying].
Topics: Animals; Cimetidine; Dogs; Dose-Response Relationship, Drug; Famotidine; Gastric Emptying; Gastrointestinal Motility; Histamine H2 Antagonists; Nizatidine; Piperidines; Ranitidine | 1993 |
Intestinal clearance of H2-antagonists.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Cimetidine; Famotidine; Histamine H2 Antagonists; Humans; Intestinal Mucosa; Jejunum; Methionine; Perfusion; Rats | 1994 |
Effects of antisecretory agents on parietal cell structure and H/K-ATPase levels in rabbit gastric mucosa in vivo.
Topics: Animals; Blotting, Western; Cimetidine; Drug Interactions; Famotidine; Gastric Acid; Gastric Mucosa; H(+)-K(+)-Exchanging ATPase; Male; Microscopy, Electron; Omeprazole; Parietal Cells, Gastric; Rabbits | 1994 |
Structural characteristics of histamine H2 receptor antagonists that scavenge hypochlorous acid.
Topics: Cimetidine; Famotidine; Free Radical Scavengers; Histamine H2 Antagonists; Hypochlorous Acid; Pancreatic Elastase; Ranitidine; Structure-Activity Relationship | 1994 |
H2-receptor antagonists are scavengers of oxygen radicals.
Topics: Chloramines; Cimetidine; Famotidine; Free Radical Scavengers; Hydroxyl Radical; Hypochlorous Acid; Oxidative Stress; Ranitidine | 1994 |
In-vitro potencies of histamine H2-receptor antagonists on tetraethylammonium uptake in rat renal brush-border membrane vesicles.
Topics: Alkaline Phosphatase; Animals; Cimetidine; Famotidine; In Vitro Techniques; Kidney; Male; Microvilli; Ranitidine; Rats; Rats, Wistar; Tetraethylammonium; Tetraethylammonium Compounds | 1994 |
Gastroprokinetic activity of nizatidine, a new H2-receptor antagonist, and its possible mechanism of action in dogs and rats.
Topics: Animals; Cholinesterase Inhibitors; Cimetidine; Digestive System; Digestive System Physiological Phenomena; Dogs; Dose-Response Relationship, Drug; Famotidine; Fasting; Gastric Acid; Gastric Emptying; Gastrointestinal Motility; Histamine H2 Antagonists; Humans; Male; Motor Activity; Nizatidine; Pylorus; Rats; Rats, Sprague-Dawley | 1993 |
Pharmacological profiles of the new histamine H2-receptor antagonist N-ethyl-N'-[3-[3-(piperidinomethyl)phenoxy] propyl] urea.
Topics: Animals; Cerebral Cortex; Cimetidine; Dogs; Famotidine; Food; Gastric Acid; Guinea Pigs; Heart Atria; Heart Rate; Histamine H2 Antagonists; In Vitro Techniques; Kinetics; Male; Phenylurea Compounds; Piperidines; Pylorus; Rats; Rats, Wistar; Tetragastrin | 1993 |
Effects of histamine type-2 receptor antagonists on indomethacin and IL-2 immunotherapy of metastasis.
Topics: Adenocarcinoma; Adjuvants, Immunologic; Animals; Cimetidine; Famotidine; Female; Histamine H2 Antagonists; Immunotherapy, Adoptive; Indomethacin; Interleukin-2; Killer Cells, Natural; Lung Neoplasms; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C3H; Neoplasm Metastasis; Neoplasm Transplantation; Ranitidine | 1993 |
Gastric antisecretory effect of FRG-8813, a new histamine H2 receptor antagonist, in rats and dogs.
Topics: Acetamides; Animals; Cimetidine; Dogs; Famotidine; Gastric Acid; Gastric Mucosa; Histamine; Histamine Agonists; Histamine H2 Antagonists; In Vitro Techniques; Ligation; Male; Perfusion; Piperidines; Pyridines; Rats; Rats, Sprague-Dawley | 1993 |
Anti-oxidant properties of H2-receptor antagonists. Effects on myeloperoxidase-catalysed reactions and hydroxyl radical generation in a ferrous-hydrogen peroxide system.
Topics: Antioxidants; Cimetidine; Famotidine; Ferrous Compounds; Histamine H2 Antagonists; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Hypochlorous Acid; Iron Chelating Agents; NAD; Nizatidine; Peroxidase; Ranitidine | 1993 |
Parenteral control of gastric acid hypersecretion in patients with Zollinger-Ellison syndrome.
Topics: Administration, Oral; Cimetidine; Dose-Response Relationship, Drug; Famotidine; Female; Gastric Acid; Histamine H2 Antagonists; Humans; Infusions, Intravenous; Male; Middle Aged; Prospective Studies; Ranitidine; Time Factors; Zollinger-Ellison Syndrome | 1993 |
Effect of the novel histamine H2-antagonist 5,6-dimethyl-2-[4-[3-(1- piperidinomethyl)phenoxy]-(z)-2-butenylamino]-4(1H)-pyrimidine dihydrochloride on histamine-induced gastric acid secretion in Heidenhain pouch dogs.
Topics: Administration, Oral; Animals; Cimetidine; Dogs; Dose-Response Relationship, Drug; Famotidine; Gastric Acid; Gastric Mucosa; Histamine; Histamine H2 Antagonists; Injections, Intravenous; Male; Piperidines; Pyrimidinones | 1993 |
Hepatitis following treatments with famotidine and then cimetidine.
Topics: Chemical and Drug Induced Liver Injury; Cimetidine; Duodenal Ulcer; Famotidine; Fatty Liver; Female; Humans; Middle Aged; Omeprazole | 1994 |
Increase of human platelet serotonin uptake by atypical histamine receptors.
Topics: Adult; Aminoquinolines; Biological Transport; Blood Platelets; Cimetidine; Cyclic AMP; Dimaprit; Famotidine; Female; Histamine Antagonists; Histidine; Humans; Imipramine; Impromidine; In Vitro Techniques; Male; Metiamide; Middle Aged; Models, Biological; Platelet Aggregation; Receptors, Histamine; Serotonin | 1994 |
Long term acid suppressing treatment in general practice.
Topics: Abdominal Pain; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Child; Child, Preschool; Cimetidine; Drug Utilization; Duodenal Ulcer; England; Esophageal Diseases; Family Practice; Famotidine; Female; Gastric Acid; Humans; Long-Term Care; Male; Middle Aged; Nizatidine; Patient Satisfaction; Ranitidine | 1994 |
Use of i.v. cimetidine, ranitidine, and famotidine in 40 hospitals.
Topics: Adolescent; Adult; Cimetidine; Concurrent Review; Drug Interactions; Drug Utilization Review; Famotidine; Hospitals; Humans; Infusions, Intravenous; Ranitidine; Southeastern United States | 1993 |
Restoration of bactericidal activity of peritoneal fluid by cimetidine but not ranitidine or famotidine in burned mice.
Topics: Animals; Ascitic Fluid; Bacteria; Burns; Cimetidine; Famotidine; Female; Immune Tolerance; Mice; Peritoneal Lavage; Ranitidine | 1993 |
Risk for adverse events among patients receiving intravenous histamine2-receptor antagonists.
Topics: Age Factors; Cimetidine; Drug Interactions; Famotidine; Female; Humans; Injections, Intravenous; Kidney Diseases; Male; Ranitidine; Regression Analysis; Risk Factors | 1993 |
Histamine-2-receptor blockade does not affect hyperemia after cerebral ischemia in young swine.
Topics: Animals; Brain Ischemia; Cerebrovascular Circulation; Cimetidine; Famotidine; Hyperemia; Intracranial Pressure; Microspheres; Oxygen Consumption; Prospective Studies; Pulmonary Gas Exchange; Random Allocation; Swine | 1993 |
Famotidine and theophylline pharmacokinetics. An unexpected cimetidine-like interaction in patients with chronic obstructive pulmonary disease.
Topics: Cimetidine; Drug Interactions; Famotidine; Humans; Infusions, Intravenous; Lung Diseases, Obstructive; Male; Middle Aged; Peptic Ulcer; Theophylline | 1993 |
Comparative effects of cimetidine and famotidine on the vagally stimulated acid secretion in the isolated mouse whole stomach.
Topics: Acetylcholine; Animals; Cimetidine; Drug Interactions; Electric Stimulation; Famotidine; Gastric Acid; Gastric Mucosa; Guinea Pigs; Ileum; In Vitro Techniques; Male; Mice; Muscle Contraction; Muscle, Smooth; Vagus Nerve | 1993 |
Evaluation of the pharmacokinetic interaction between cimetidine or famotidine and cyclosporine in healthy men.
Topics: Adult; Cimetidine; Cross-Over Studies; Cyclosporine; Drug Interactions; Famotidine; Histamine H2 Antagonists; Hospitals, University; Humans; Male | 1995 |
The effect of three H2 receptor antagonists on the disposition of cyclosporin A in the in situ perfused rat liver model.
Topics: Analysis of Variance; Animals; Chromatography, High Pressure Liquid; Cimetidine; Cyclosporine; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme Inhibitors; Drug Interactions; Famotidine; Histamine H2 Antagonists; Immunosuppressive Agents; Isoenzymes; Liver; Male; Mixed Function Oxygenases; Ranitidine; Rats; Rats, Sprague-Dawley | 1995 |
Inhibition of choline uptake in syncytial microvillus membrane vesicles of human term placenta. Specificity and nature of interaction.
Topics: Atropine; Carrier Proteins; Choline; Cholinergic Antagonists; Cimetidine; Dose-Response Relationship, Drug; Famotidine; Female; Hemicholinium 3; Histamine H2 Antagonists; Humans; In Vitro Techniques; Maternal-Fetal Exchange; Membrane Transport Proteins; Microvilli; Neurotransmitter Uptake Inhibitors; Placenta; Pregnancy; Ranitidine; Tetraethylammonium Compounds; Trophoblasts | 1995 |
Neurotoxic convulsions induced by histamine H2 receptor antagonists in mice.
Topics: Animals; Anticonvulsants; Brain; Cimetidine; Convulsants; Famotidine; GABA Agonists; Histamine H2 Antagonists; Injections, Intraventricular; Male; Mice; Models, Biological; Nizatidine; Ranitidine; Receptors, Histamine H2; Seizures | 1996 |
Reversion by histamine H2-receptor antagonists of plasma membrane alterations in ethanol-induced gastritis.
Topics: Animals; Cell Membrane; Cholesterol; Cimetidine; Ethanol; Famotidine; Gastric Mucosa; Gastritis; Histamine H2 Antagonists; Male; Phospholipids; Ranitidine; Rats; Rats, Wistar | 1996 |
Is the incidence of hemorrhagic stress ulceration in surgical critically ill patients affected by modern antacid prophylaxis?
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antacids; Anti-Ulcer Agents; Cimetidine; Critical Care; Famotidine; Gastroscopy; Humans; Incidence; Length of Stay; Middle Aged; Nutritional Status; Peptic Ulcer Hemorrhage; Ranitidine; Retrospective Studies; Stomach Ulcer; Sucralfate; Survival Rate | 1996 |
[Effect of a novel antiulcer drug, lafutidine, on experimental chronic gastritis in rats].
Topics: Acetamides; Ammonia; Animals; Anti-Ulcer Agents; Cell Count; Chronic Disease; Cimetidine; Famotidine; Gastric Mucosa; Gastritis; Humans; Male; Parietal Cells, Gastric; Piperidines; Pyridines; Rats; Rats, Sprague-Dawley; Taurocholic Acid | 1997 |
Effect of ebrotidine on ethanol-induced gastric mucosal damage in the rat. Comparative study with other H2-receptor antagonists.
Topics: Animals; Benzenesulfonates; Cimetidine; Dose-Response Relationship, Drug; Ethanol; Famotidine; Female; Gastric Mucosa; Histamine H2 Antagonists; Indomethacin; Peptic Ulcer; Ranitidine; Rats; Rats, Sprague-Dawley; Thiazoles | 1997 |
Effects of cimetidine on acute gastric mucosal injury induced by ischemia-reperfusion in rats.
Topics: Animals; Anti-Ulcer Agents; Cimetidine; Erythrocyte Membrane; Famotidine; Gastric Mucosa; Histamine H2 Antagonists; Lipid Peroxidation; Male; Omeprazole; Rats; Rats, Wistar; Reperfusion Injury; Stomach Diseases | 1997 |
H2-receptor antagonist reduces food intake and weight gain in rats by non-gastric acid secretory mechanisms.
Topics: Animals; Anti-Ulcer Agents; Cimetidine; Eating; Famotidine; Gastric Acid; Histamine H2 Antagonists; Male; Omeprazole; Ranitidine; Rats; Rats, Wistar; Weight Gain | 1997 |
Bone mineral density in patients taking H2-receptor antagonist.
Topics: Adult; Aged; Bone Density; Case-Control Studies; Cimetidine; Duodenal Ulcer; Famotidine; Female; Histamine H2 Antagonists; Humans; Male; Middle Aged; Multivariate Analysis; Osteoporosis; Ranitidine; Stomach Ulcer; Time Factors | 1998 |
Do OTC 'ulcer drugs' pose problems when used with dental medications?
Topics: Anesthesia, Dental; Anti-Bacterial Agents; Anti-Ulcer Agents; Binding, Competitive; Cimetidine; Drug Interactions; Famotidine; Headache; Histamine H2 Antagonists; Humans; Nonprescription Drugs | 1995 |
[Effect of lafutidine, a novel antiulcer agent, on healing and relapse of acetic acid-induced gastric ulcer in rats].
Topics: Acetamides; Acetic Acid; Animals; Anti-Ulcer Agents; Cimetidine; Dose-Response Relationship, Drug; Famotidine; Histamine H2 Antagonists; Male; Piperidines; Pyridines; Rats; Rats, Sprague-Dawley; Recurrence; Stomach Ulcer | 1998 |
Constitutive activity and structural instability of the wild-type human H2 receptor.
Topics: Animals; Binding, Competitive; Burimamide; CHO Cells; Cimetidine; Cricetinae; Cyclic AMP; Dose-Response Relationship, Drug; Down-Regulation; Famotidine; Gene Expression; Histamine H2 Antagonists; Humans; Ranitidine; Receptors, Histamine H2; Up-Regulation | 1998 |
An antibody from a patient with ranitidine-induced thrombocytopenia recognizes a site on glycoprotein IX that is a favored target for drug-induced antibodies.
Topics: Aged; Animals; Anti-Ulcer Agents; Antibodies, Monoclonal; Antibody Specificity; Antigen-Antibody Reactions; Autoantibodies; Autoimmune Diseases; Blood Platelets; CHO Cells; Cimetidine; Cricetinae; Cricetulus; Epitopes; Famotidine; Female; Flow Cytometry; Histamine H2 Antagonists; Humans; Molecular Structure; Nizatidine; Platelet Glycoprotein GPIb-IX Complex; Precipitin Tests; Protein Conformation; Quinidine; Quinine; Ranitidine; Recombinant Fusion Proteins; Structure-Activity Relationship; Thrombocytopenia; Transfection | 1998 |
Antiulcer drug prescribing in hospital successfully influenced by "immediate concurrent feedback".
Topics: Administration, Oral; Anti-Ulcer Agents; Cimetidine; Cost-Benefit Analysis; Drug Utilization; Famotidine; Feedback; Hong Kong; Hospitals, Teaching; Humans; Infusions, Intravenous; Medical Audit; Nizatidine; Omeprazole; Practice Patterns, Physicians'; Ranitidine | 1998 |
Using multiple pharmacoeconomic methods to conduct a cost-effectiveness analysis of histamine H2-receptor antagonists.
Topics: Cimetidine; Cost-Benefit Analysis; Decision Trees; Famotidine; Female; Histamine H2 Antagonists; Humans; Iowa; Male; Middle Aged; Peptic Ulcer; Sensitivity and Specificity; Stress, Physiological | 1998 |
Interaction of the new histamine H2-receptor antagonist pibutidine hydrochloride with canine cloned H2-receptor expressed cells.
Topics: Alanine; Animals; Cell Line; Cimetidine; Dogs; Famotidine; Histamine H2 Antagonists; Ligands; Mice; Mutation; Piperidines; Pyridines; Ranitidine; Receptors, Histamine H2; Transfection | 1999 |
Simultaneous high-performance liquid chromatographic analysis for famotidine, ranitidine HCl, cimetidine, and nizatidine in commercial products.
Topics: Algorithms; Chromatography, High Pressure Liquid; Cimetidine; Famotidine; Histamine H2 Antagonists; Nizatidine; Ranitidine; Regression Analysis; Reproducibility of Results; Solvents; Spectrophotometry, Ultraviolet | 1999 |
Drug usage evaluation: H2-receptor antagonist use in 30 hospitals.
Topics: Adverse Drug Reaction Reporting Systems; Aged; Cimetidine; Data Collection; Drug Interactions; Drug Utilization; Famotidine; Female; Forms and Records Control; Humans; Male; Middle Aged; Ranitidine; Receptors, Histamine H2; United States | 1991 |
Strategy for developing a safe and cost-effective H2-receptor antagonist program.
Topics: Cimetidine; Clinical Protocols; Connecticut; Cost Savings; Drug Costs; Drug Interactions; Drug Utilization; Famotidine; Formularies, Hospital as Topic; Histamine H2 Antagonists; Hospital Bed Capacity, 500 and over; Humans; Pharmacy and Therapeutics Committee; Pharmacy Service, Hospital; Safety | 1991 |
Criteria-based DUE aids in selection of preferred agent.
Topics: Cimetidine; Cost Savings; Data Collection; Drug Costs; Drug Utilization; Famotidine; Forms and Records Control; Formularies, Hospital as Topic; Histamine H2 Antagonists; Hospital Bed Capacity, 500 and over; Humans; Illinois; Pharmacy and Therapeutics Committee | 1991 |
Retrospective analysis of formulary restriction demonstrates significant cost savings.
Topics: Cimetidine; Cost Savings; Drug Utilization; Famotidine; Formularies, Hospital as Topic; Histamine H2 Antagonists; Hospital Bed Capacity, 300 to 499; Humans; Michigan; Pharmacy Service, Hospital; Ranitidine | 1991 |
A pharmacoeconomic analysis of IV H2-receptor antagonist use in 40 hospitals.
Topics: Cimetidine; Data Collection; Drug Costs; Drug Utilization Review; Famotidine; Histamine H2 Antagonists; Hospital Costs; Hospitals; Humans; Pharmacy Service, Hospital; Ranitidine; Southeastern United States | 1994 |
Role of endogenous serotonin and histamine in the pathogenesis of gastric mucosal lesions in unanaesthetised rats with a single treatment of compound 48/80, a mast cell degranulator.
Topics: Adrenergic Uptake Inhibitors; Amitriptyline; Animals; Cell Degranulation; Cimetidine; Cyproheptadine; Famotidine; Gastric Mucosa; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Male; Mast Cells; Methysergide; p-Methoxy-N-methylphenethylamine; Rats; Rats, Wistar; Serotonin; Serotonin Antagonists; Stomach Ulcer; Tripelennamine | 1999 |
The effects of cimetidine, ranitidine, and famotidine on human neutrophil functions.
Topics: Calcium; Cimetidine; Dose-Response Relationship, Drug; Famotidine; Histamine H2 Antagonists; Humans; Neutrophils; Ranitidine; Reactive Oxygen Species | 1999 |
Gastroprokinetic activity of nizatidine during the digestive state in the dog and rat.
Topics: Animals; Anti-Ulcer Agents; Cimetidine; Cisapride; Digestion; Dogs; Duodenum; Famotidine; Gastric Emptying; Gastrointestinal Motility; Injections, Intravenous; Intubation, Gastrointestinal; Male; Nizatidine; Rats; Rats, Sprague-Dawley; Stimulation, Chemical; Stomach | 1999 |
Antiulcer effect of lafutidine on indomethacin-induced gastric antral ulcers in refed rats.
Topics: 16,16-Dimethylprostaglandin E2; Acetamides; Administration, Oral; Animals; Anti-Ulcer Agents; Capsaicin; Cimetidine; Denervation; Dose-Response Relationship, Drug; Enzyme Inhibitors; Famotidine; Food; Indomethacin; Male; Nitroarginine; Piperidines; Pyloric Antrum; Pyridines; Rats; Rats, Sprague-Dawley; Stomach Ulcer; Wound Healing | 1999 |
Inhibitory effects of H2-receptor antagonists on platelet function in vitro.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Aspirin; Blood Platelets; Cimetidine; Collagen; Famotidine; Female; Heterocyclic Compounds, 1-Ring; Histamine H2 Antagonists; Humans; In Vitro Techniques; Male; Middle Aged; P-Selectin; Piperidines; Platelet Aggregation; Platelet Aggregation Inhibitors; Ranitidine; Structure-Activity Relationship | 1999 |
Chitosan microspheres prepared by spray drying.
Topics: Biocompatible Materials; Biopolymers; Calorimetry, Differential Scanning; Chitin; Chitosan; Cimetidine; Cross-Linking Reagents; Delayed-Action Preparations; Famotidine; Histamine H2 Antagonists; Microscopy, Electron, Scanning; Microspheres; Molecular Weight; Nizatidine; Particle Size; Viscosity | 1999 |
Famotidine-induced erythema multiforme: cross-sensitivity with cimetidine.
Topics: Cimetidine; Drug Synergism; Erythema Multiforme; Famotidine; Histamine H2 Antagonists; Humans | 1999 |
Long-lasting binding of IT-066 to human histamine H2 receptor.
Topics: Animals; Anti-Ulcer Agents; CHO Cells; Cimetidine; Cricetinae; Cyclic AMP; Famotidine; Fixatives; Formaldehyde; Histamine H2 Antagonists; Piperidines; Polymers; Protein Binding; Pyridines; Ranitidine; Receptors, Histamine H2 | 2000 |
Cimetidine inhibits cancer cell adhesion to endothelial cells and prevents metastasis by blocking E-selectin expression.
Topics: Animals; Cell Adhesion; Cell Nucleus; Cimetidine; Colorectal Neoplasms; Dose-Response Relationship, Drug; Down-Regulation; E-Selectin; Endothelium, Vascular; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Famotidine; Histamine H2 Antagonists; Humans; Interleukin-1; Liver Neoplasms; Mice; Mice, Nude; Microscopy, Confocal; Neoplasm Transplantation; NF-kappa B; Oligosaccharides; Ranitidine; RNA, Messenger; Sialyl Lewis X Antigen; Transcriptional Activation; Tumor Cells, Cultured; Umbilical Veins | 2000 |
[Activity of malondialdehyde in rat plasma after H2 histamine receptor blockade].
Topics: Animals; Cimetidine; Famotidine; Histamine H2 Antagonists; Injections, Intraperitoneal; Male; Malondialdehyde; Ranitidine; Rats; Rats, Wistar | 1999 |
Head-column field-amplified sample stacking in capillary electrophoresis for the determination of cimetidine, famotidine, nizatidine, and ranitidine-HCl in plasma.
Topics: Buffers; Cimetidine; Electric Conductivity; Electrophoresis, Capillary; Ethylene Glycol; Famotidine; Histamine H2 Antagonists; Humans; Nizatidine; Phosphates; Ranitidine; Sensitivity and Specificity; Time Factors; Water | 2001 |
Simultaneous determination of cimetidine, famotidine, nizatidine, and ranitidine in tablets by capillary zone electrophoresis.
Topics: Anti-Ulcer Agents; Buffers; Calibration; Cimetidine; Famotidine; Histamine H2 Antagonists; Hydrogen-Ion Concentration; Molecular Structure; Nizatidine; Phosphates; Ranitidine; Tablets; Time Factors | 2001 |
Delirium following a switch from cimetidine to famotidine.
Topics: Aged; Anti-Ulcer Agents; Cimetidine; Delirium; Famotidine; Female; Humans; Stomach Ulcer | 2001 |
Potent and long-lasting action of lafutidine on the human histamine H(2) receptor.
Topics: Acetamides; Animals; CHO Cells; Cimetidine; Cricetinae; Cyclic AMP; Dose-Response Relationship, Drug; Famotidine; Histamine H2 Antagonists; Humans; Piperidines; Pyridines; Receptors, Histamine H2; Transfection | 2001 |
Cimetidine modulates the antigen presenting capacity of dendritic cells from colorectal cancer patients.
Topics: Adult; Aged; Antigen Presentation; Cell Differentiation; Cimetidine; Colorectal Neoplasms; Dendritic Cells; Famotidine; Female; Flow Cytometry; Humans; Interleukin-12; Male; Middle Aged | 2002 |
Susceptibility of the H2-receptor antagonists cimetidine, famotidine and nizatidine, to metabolism by the gastrointestinal microflora.
Topics: Bacteria, Anaerobic; Cimetidine; Digestive System; Famotidine; Female; Histamine H2 Antagonists; Humans; Nizatidine | 2002 |
Effects of N-alpha-methyl-histamine on human H(2) receptors expressed in CHO cells.
Topics: Animals; CHO Cells; Cimetidine; Cricetinae; Cyclic AMP; Famotidine; Female; Histamine Agonists; Histamine Antagonists; Histamine H2 Antagonists; Methylhistamines; Ovary; Piperidines; Receptors, Histamine H2; Receptors, Histamine H3 | 2002 |
Effects of three H2-receptor antagonists (cimetidine, famotidine, ranitidine) on serum gastrin level.
Topics: Adult; Anti-Ulcer Agents; Area Under Curve; Cimetidine; Duodenal Ulcer; Famotidine; Female; Gastrins; Histamine H2 Antagonists; Humans; Male; Middle Aged; Multivariate Analysis; Ranitidine; Receptors, Histamine H2; Statistics, Nonparametric; Stomach Ulcer | 2002 |
Enhancing and inhibitory effects of H2-receptor antagonists on the GABA and the GABAA-agonist muscimol responses of the isolated guinea pig ileum: a pharmacodynamic interaction.
Topics: Animals; Cimetidine; Dose-Response Relationship, Drug; Drug Interactions; Famotidine; Female; GABA Agonists; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Guinea Pigs; Histamine H2 Antagonists; Ileum; In Vitro Techniques; Male; Muscimol; Muscle Contraction; Receptors, GABA; Receptors, GABA-A | 2003 |
Spermicidal efficacy of H2-receptor antagonists and potentiation with 2', 4'-dichlorobenzamil hydrochloride: role of intrasperm Ca2+.
Topics: Adult; Amiloride; Calcium; Cimetidine; Famotidine; Histamine H2 Antagonists; Humans; In Vitro Techniques; Male; Ranitidine; Receptors, Cytoplasmic and Nuclear; Sodium-Calcium Exchanger; Sperm Motility; Spermatocidal Agents; Spermatozoa; Time Factors | 2003 |
Activity of cathepsin B, D and L in rat cerebrum after cimetidine and famotidine administration.
Topics: Animals; Biomarkers; Cathepsin B; Cathepsin D; Cathepsin L; Cathepsins; Cimetidine; Cysteine Endopeptidases; Dose-Response Relationship, Drug; Famotidine; Frontal Lobe; Histamine H2 Antagonists; Male; Rats; Rats, Wistar | 2003 |
Development of an HPLC method for the determination of ranitidine and cimetidine in human plasma following SPE.
Topics: Calibration; Chromatography, High Pressure Liquid; Cimetidine; Famotidine; Histamine H2 Antagonists; Humans; Quality Control; Ranitidine; Reproducibility of Results; Spectrophotometry, Ultraviolet | 2003 |
Radioprotective properties of histamine H2 receptor antagonists: present and future prospects.
Topics: Animals; Bone Marrow Cells; Cimetidine; Famotidine; Histamine H2 Antagonists; Male; Mice; Mice, Inbred BALB C; Radiation-Protective Agents; Ranitidine; Whole-Body Irradiation | 2003 |
[Reduction of cardiovascular disorders by preventive perioperative antihistamine administration in general surgery: are the drugs interchangeable?].
Topics: Animals; Cardiovascular Diseases; Cimetidine; Dimethindene; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Therapy, Combination; Famotidine; Female; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Male; Postoperative Complications; Premedication; Randomized Controlled Trials as Topic; Ranitidine; Swine | 1998 |
Histamine participates in the early phase of trabecular bone loss in ovariectomized rats.
Topics: Animals; Body Weight; Bone Resorption; Cimetidine; Famotidine; Female; Femur; Histamine; Immunohistochemistry; Kinetics; Mast Cells; Osteoclasts; Ovariectomy; Rats | 2004 |
Carrier-mediated uptake of H2-receptor antagonists by the rat choroid plexus: involvement of rat organic anion transporter 3.
Topics: Animals; Carbon Radioisotopes; Carrier Proteins; Cerebrospinal Fluid; Choroid Plexus; Cimetidine; Dose-Response Relationship, Drug; Famotidine; Histamine H2 Antagonists; Male; Models, Molecular; Molecular Structure; Organic Cation Transport Proteins; Penicillin G; Probenecid; Ranitidine; Rats; Rats, Sprague-Dawley; Static Electricity; Tetraethylammonium; Tritium | 2004 |
Effects of cimetidine-like drugs on recombinant GABAA receptors.
Topics: Cell Line; Cimetidine; Dose-Response Relationship, Drug; Famotidine; Fibroblasts; Histamine H2 Antagonists; Humans; Patch-Clamp Techniques; Ranitidine; Receptors, GABA-A; Recombinant Proteins | 2004 |
Different transport properties between famotidine and cimetidine by human renal organic ion transporters (SLC22A).
Topics: Animals; Chromatography, High Pressure Liquid; Cimetidine; Famotidine; Histamine H2 Antagonists; Humans; Kidney; Kinetics; Oocytes; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; Organic Cation Transport Proteins; Organic Cation Transporter 2; p-Aminohippuric Acid; Xenopus laevis | 2004 |
Alteration of intracellular histamine H2 receptor cycling precedes antagonist-induced upregulation.
Topics: Cell Line; Cimetidine; Famotidine; Histamine H2 Antagonists; Humans; Protein Transport; Ranitidine; Receptors, Histamine H2; RNA, Messenger; Up-Regulation | 2005 |
In vitro availability of metformin in presence of h(2) receptor antagonists.
Topics: Cimetidine; Famotidine; Gastric Juice; Histamine H2 Antagonists; Hydrogen-Ion Concentration; Intestinal Secretions; Metformin; Ranitidine | 2006 |
Fosinopril H(2)-receptor antagonists interaction studies by derivative spectroscopy.
Topics: Angiotensin-Converting Enzyme Inhibitors; Buffers; Cimetidine; Drug Interactions; Famotidine; Fosinopril; Histamine H2 Antagonists; Hydrogen-Ion Concentration; Least-Squares Analysis; Linear Models; Models, Chemical; Ranitidine; Solubility; Spectrophotometry, Ultraviolet; Temperature; Thermodynamics | 2007 |
In vitro interactions of captopril with H2-receptor antagonists.
Topics: Angiotensin-Converting Enzyme Inhibitors; Anti-Ulcer Agents; Antihypertensive Agents; Captopril; Cimetidine; Drug Interactions; Famotidine; Gastric Juice; Histamine H2 Antagonists; Hydrogen-Ion Concentration; Kinetics; Models, Chemical; Ranitidine; Solubility; Temperature; Thermodynamics | 2007 |
Spectrophotometric determination of H(2)-receptor antagonists via their oxidation with cerium(IV).
Topics: Aminobenzoates; Cerium; Cimetidine; Dosage Forms; Excipients; Famotidine; Histamine H2 Antagonists; Nizatidine; Oxidation-Reduction; Ranitidine; Reproducibility of Results; Solvents; Spectrophotometry; Time Factors | 2008 |
In vitro availability studies of enoxacin in presence of H2 receptor antagonists.
Topics: Anti-Bacterial Agents; Anti-Ulcer Agents; Cimetidine; Drug Interactions; Enoxacin; Famotidine; Gastric Juice; Gram-Negative Bacteria; Gram-Positive Bacteria; Histamine H2 Antagonists; Hydrogen-Ion Concentration; Microbial Sensitivity Tests; Ranitidine; Solubility; Temperature | 2007 |
Comparison of the kinetic characteristics of inhibitory effects exerted by biguanides and H2-blockers on human and rat organic cation transporter-mediated transport: Insight into the development of drug candidates.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Biguanides; Cell Line; Cimetidine; Drug Design; Famotidine; Histamine H2 Antagonists; Humans; Ion Transport; Kinetics; Metformin; Organic Cation Transport Proteins; Phenformin; Ranitidine; Rats; Tetraethylammonium | 2007 |
Simple and universal HPLC-UV method to determine cimetidine, ranitidine, famotidine and nizatidine in urine: application to the analysis of ranitidine and its metabolites in human volunteers.
Topics: Chromatography, High Pressure Liquid; Cimetidine; Famotidine; Histamine H2 Antagonists; Humans; Nizatidine; Ranitidine; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet | 2007 |
Relationship between histamine2-receptor antagonist medications and risk of invasive breast cancer.
Topics: Aged; Anti-Ulcer Agents; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Lobular; Case-Control Studies; Cimetidine; Famotidine; Female; Histamine H2 Antagonists; Humans; Middle Aged; Neoplasm Invasiveness; Ranitidine; Risk Factors; Washington | 2008 |
The safety of H(2)-blockers use during pregnancy.
Topics: Abnormalities, Drug-Induced; Abortion, Therapeutic; Adolescent; Adult; Apgar Score; Cimetidine; Cohort Studies; Famotidine; Female; Histamine H2 Antagonists; Humans; Infant, Low Birth Weight; Infant, Newborn; Maternal-Fetal Exchange; Medical Records Systems, Computerized; Middle Aged; Perinatal Mortality; Pregnancy; Pregnancy Complications; Pregnancy Trimester, First; Premature Birth; Ranitidine; Retrospective Studies | 2010 |
A single LC-tandem mass spectrometry method for the simultaneous determination of four H2 antagonists in human plasma.
Topics: Acetamides; Calibration; Chromatography, Liquid; Cimetidine; Famotidine; Histamine H2 Antagonists; Humans; Piperidines; Pyridines; Ranitidine; Reproducibility of Results; Tandem Mass Spectrometry; Therapeutic Equivalency | 2009 |
Hepatoprotective, antinociceptive and antioxidant activities of cimetidine, ranitidine and famotidine as histamine H2 receptor antagonists.
Topics: Analgesics; Animals; Antioxidants; Carbon Tetrachloride; Cimetidine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Famotidine; Histamine H2 Antagonists; Inhibitory Concentration 50; Liver; Liver Function Tests; Male; Mice; Protective Agents; Ranitidine | 2011 |
Protective effect of lafutidine, a histamine H2 receptor antagonist, against loxoprofen-induced small intestinal lesions in rats.
Topics: 16,16-Dimethylprostaglandin E2; Acetamides; Ampicillin; Animals; Anti-Bacterial Agents; Anti-Ulcer Agents; Capsaicin; Cimetidine; Disease Models, Animal; Enterobacteriaceae; Famotidine; Histamine H2 Antagonists; Intestinal Mucosa; Intestine, Small; Male; Mucin-2; Nitric Oxide Synthase Type II; Omeprazole; Peptic Ulcer; Peroxidase; Phenylpropionates; Piperidines; Proton Pump Inhibitors; Pyridines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sensory Receptor Cells | 2010 |
Protective effect of roxatidine against indomethacin-induced small intestinal mucosal injury in rats.
Topics: Animals; Anti-Ulcer Agents; Cimetidine; Disease Models, Animal; Famotidine; Histamine H2 Antagonists; Indomethacin; Intestinal Mucosa; Intestine, Small; Male; Mucus; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Peptic Ulcer; Piperidines; Prostaglandins; Rats; Rats, Sprague-Dawley | 2010 |
Simultaneous determination of metformin, cimetidine, famotidine, and ranitidine in human serum and dosage formulations using HPLC with UV detection.
Topics: Adult; Chromatography, High Pressure Liquid; Cimetidine; Ethylamines; Famotidine; Histamine H2 Antagonists; Humans; Hydrogen-Ion Concentration; Linear Models; Metformin; Methanol; Ranitidine; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Tablets; Young Adult | 2010 |
In vitro evaluation of phototoxic properties of proton pump inhibitors, H2-receptor antagonists and statins.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Ascorbic Acid; Cimetidine; Erythrocytes; Famotidine; Hemolysis; Histamine H2 Antagonists; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lansoprazole; Lovastatin; Nizatidine; Omeprazole; Pantoprazole; Pravastatin; Proton Pump Inhibitors; Ranitidine; Ultraviolet Rays | 2012 |
Application of vibrational spectroscopy, thermal analyses and X-ray diffraction in the rapid evaluation of the stability in solid-state of ranitidine, famotidine and cimetidine.
Topics: Calorimetry, Differential Scanning; Cimetidine; Drug Stability; Famotidine; Histamine H2 Antagonists; Ranitidine; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman; Vibration; X-Ray Diffraction | 2015 |
Molecular modelling studies on 2-substituted octahydropyrazinopyridoindoles for histamine H2 receptor antagonism.
Topics: Cimetidine; Computer Simulation; Famotidine; Histamine H2 Antagonists; Humans; Indoles; Metiamide; Molecular Docking Simulation; Pyrazines; Pyridines; Ranitidine; Receptors, Histamine H2; Sequence Homology, Amino Acid; Structure-Activity Relationship | 2015 |
Molecular Encapsulation of Histamine H₂-Receptor Antagonists by Cucurbit[7]Uril: An Experimental and Computational Study.
Topics: Bridged-Ring Compounds; Cimetidine; Famotidine; Histamine H2 Antagonists; Imidazoles; Molecular Dynamics Simulation; Nizatidine | 2016 |
The Slow Relaxation Dynamics in the Amorphous Pharmaceutical Drugs Cimetidine, Nizatidine, and Famotidine.
Topics: Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Cimetidine; Famotidine; Nizatidine; Time Factors | 2016 |
In vitro Spectroscopic studies on drug interaction of cefpodoxime proxetil and H2 receptor blockers.
Topics: Cefpodoxime Proxetil; Ceftizoxime; Cimetidine; Drug Interactions; Famotidine; Histamine H2 Antagonists; Ranitidine; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet | 2019 |
Relevance of Hydrogen Bonds for the Histamine H2 Receptor-Ligand Interactions: A Lesson from Deuteration.
Topics: Binding Sites; Cimetidine; Density Functional Theory; Deuterium; Drug Design; Famotidine; Humans; Hydrogen Bonding; Ligands; Methylhistamines; Normal Distribution; Protein Binding; Protons; Receptors, Histamine H2; Water | 2020 |
Molecular recognizable ion-paired complex formation between diclofenac/indomethacin and famotidine/cimetidine regulates their aqueous solubility.
Topics: Cimetidine; Diclofenac; Famotidine; Indomethacin; Solubility; Water | 2020 |
Molecular basis for the repurposing of histamine H2-receptor antagonist to treat COVID-19.
Topics: Cimetidine; COVID-19 Drug Treatment; Famotidine; Histamine; Histamine H2 Antagonists; Humans; Molecular Docking Simulation | 2022 |
Synthesis and antiulcer activity of N-substituted N'-[3-[3-(piperidinomethyl)phenoxy]propyl]ureas: histamine H2-receptor antagonists with a potent mucosal protective activity.
Topics: Animals; Anti-Ulcer Agents; Gastric Acidity Determination; Gastric Mucosa; Guinea Pigs; Histamine H2 Antagonists; In Vitro Techniques; Male; Phenylurea Compounds; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Urea | 1992 |
Studies on histamine H2 receptor antagonists. 2. Synthesis and pharmacological activities of N-sulfamoyl and N-sulfonyl amidine derivatives.
Topics: Amidines; Animals; Chromatography, High Pressure Liquid; Dogs; Famotidine; Gastric Acid; Guinea Pigs; Heart; Histamine H2 Antagonists; Magnetic Resonance Spectroscopy; Models, Molecular; Structure-Activity Relationship; Thiazoles | 1987 |
Studies on antiulcer drugs. 7. 2-Guanidino-4-pyridylthiazoles as histamine H2-receptor antagonists with potent gastroprotective effects against nonsteroidal antiinflammatory drug-induced injury.
Topics: Animals; Anti-Ulcer Agents; Aspirin; Blood Flow Velocity; Dogs; Gastric Acid; Gastric Mucosa; Guanidines; Guinea Pigs; Histamine; Histamine H2 Antagonists; Indomethacin; Male; Molecular Structure; Myocardial Contraction; Rabbits; Rats; Rats, Sprague-Dawley; Stomach Ulcer; Thiazoles | 1994 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
High-throughput permeability pH profile and high-throughput alkane/water log P with artificial membranes.
Topics: Alkanes; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Membranes, Artificial; Octanols; Permeability; Pharmaceutical Preparations; Solubility; Water | 2001 |
Synthesis and pharmacological activity of fluorescent histamine H2 receptor antagonists related to potentidine.
Topics: Animals; Fluorescent Dyes; Guanidines; Guinea Pigs; Heart Atria; Histamine H2 Antagonists; In Vitro Techniques; Propylamines; Spectrum Analysis; Structure-Activity Relationship | 2003 |
Renal transport of organic compounds mediated by mouse organic anion transporter 3 (mOat3): further substrate specificity of mOat3.
Topics: Allopurinol; Animals; Biological Transport; Dose-Response Relationship, Drug; Female; Kidney; Male; Mice; Oocytes; Organic Anion Transporters, Sodium-Independent; Substrate Specificity; Xenopus laevis | 2004 |
Evaluation of histamine H1-, H2-, and H3-receptor ligands at the human histamine H4 receptor: identification of 4-methylhistamine as the first potent and selective H4 receptor agonist.
Topics: Cell Line; Histamine Agonists; Humans; Imidazoles; Indoles; Isothiuronium; Ligands; Methylhistamines; Piperazines; Radioligand Assay; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Receptors, Histamine H3; Receptors, Histamine H4 | 2005 |
Is the monkey an appropriate animal model to examine drug-drug interactions involving renal clearance? Effect of probenecid on the renal elimination of H2 receptor antagonists.
Topics: Animals; Drug Interactions; Famotidine; Histamine H2 Antagonists; Humans; Kidney; Macaca fascicularis; Male; Models, Animal; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; Probenecid; Reverse Transcriptase Polymerase Chain Reaction | 2006 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Possible involvement of radical intermediates in the inhibition of cysteine proteases by allenyl esters and amides.
Topics: Amides; Animals; Caspase 10; Catalysis; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Esters; Molecular Structure; Oxygen; Rats; Sulfhydryl Compounds | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis | 2010 |
Discovery of potent small-molecule inhibitors of multidrug-resistant Plasmodium falciparum using a novel miniaturized high-throughput luciferase-based assay.
Topics: Animals; Antimalarials; Drug Resistance, Multiple; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
Predicting phospholipidosis using machine learning.
Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Discovery of potent, selective multidrug and toxin extrusion transporter 1 (MATE1, SLC47A1) inhibitors through prescription drug profiling and computational modeling.
Topics: Computer Simulation; Fluorescent Dyes; Organic Cation Transport Proteins; Prescription Drugs | 2013 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |