fadrozole has been researched along with eplerenone in 8 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 8 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hartmann, RW; Hu, Q; Yin, L | 2 |
| Aebi, JD; Alker, AM; Amrein, K; Burger, D; Hornsperger, B; Krebs, HJ; Kuglstatter, A; Kuhn, B; Märki, HP; Martin, RE; Mayweg, AV; Müller, S; Ottaviani, G; Riboulet, W; Tan, X; Verry, P | 1 |
| Briones, AM; Callera, GE; He, Y; Montezano, AC; Nguyen Dinh Cat, A; Touyz, RM; Yogi, A | 1 |
| Kumagai, H; Nishida, Y; Oda, T; Onimaru, H; Oshima, N; Takechi, H; Uchida, T; Watanabe, A; Yamamoto, K | 1 |
| Ahmad, M; Huang, BS; Leenen, FH; White, RA | 1 |
| Ahmad, M; Chen, A; Huang, BS; Leenen, FH; Wang, HW; White, RA | 1 |
| Bornstein, SR; Brown, NF; Brunssen, C; Deussen, A; Eisenhofer, G; Engelmann, F; Hofmann, A; Huber, J; Jannasch, A; Martin, M; Mittag, J; Morawietz, H; Peitzsch, M; Streicher, R; Weldon, SM | 1 |
8 other study(ies) available for fadrozole and eplerenone
| Article | Year |
|---|---|
Aldosterone synthase inhibitors as promising treatments for mineralocorticoid dependent cardiovascular and renal diseases.
Topics: Aldosterone; Animals; Benzimidazoles; Cardiovascular Diseases; Cytochrome P-450 CYP11B2; Fadrozole; Humans; Indans; Indoles; Kidney Diseases; Mineralocorticoids; Naphthalenes; Quinolines; Receptors, Mineralocorticoid | 2014 |
Discovery of 4-Aryl-5,6,7,8-tetrahydroisoquinolines as Potent, Selective, and Orally Active Aldosterone Synthase (CYP11B2) Inhibitors: In Vivo Evaluation in Rodents and Cynomolgus Monkeys.
Topics: Aldosterone; Animals; Cytochrome P-450 CYP11B2; Drug Design; Drug Discovery; Enzyme Inhibitors; Humans; Macaca fascicularis; Male; Mice; Mice, Inbred DBA; Mineralocorticoid Receptor Antagonists; Models, Molecular; Rats; Tetrahydroisoquinolines | 2015 |
Adipocyte-derived factors regulate vascular smooth muscle cells through mineralocorticoid and glucocorticoid receptors.
Topics: 3T3-L1 Cells; Adipocytes; Aldosterone; Angiotensin II; Animals; Blotting, Western; Cells, Cultured; Corticosterone; Culture Media, Conditioned; Eplerenone; Fadrozole; Fibronectins; Hormone Antagonists; Mice; Mice, Inbred C57BL; Mifepristone; Mineralocorticoid Receptor Antagonists; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phosphorylation; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins c-bcl-2; Receptor, Angiotensin, Type 1; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Spironolactone | 2011 |
3-Pyridyl substituted aliphatic cycles as CYP11B2 inhibitors: aromaticity abolishment of the core significantly increased selectivity over CYP1A2.
Topics: Algorithms; Androstadienes; Aromatase Inhibitors; Catalytic Domain; Cytochrome P-450 CYP11B2; Cytochrome P-450 CYP1A2 Inhibitors; Drug Design; Enalapril; Eplerenone; Fadrozole; Humans; Inhibitory Concentration 50; Models, Chemical; Models, Molecular; Molecular Conformation; Spironolactone; Structure-Activity Relationship; Temperature | 2012 |
Aldosterone is synthesized in and activates bulbospinal neurons through mineralocorticoid receptors and ENaCs in the RVLM.
Topics: Aldosterone; Amiloride; Animals; Aromatase Inhibitors; Calcium; Diuretics; Epithelial Sodium Channels; Eplerenone; Excitatory Postsynaptic Potentials; Fadrozole; Magnesium; Medulla Oblongata; Membrane Potentials; Neurons; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, Mineralocorticoid; Spinal Cord; Spironolactone; Tissue Fixation | 2013 |
Role of brain corticosterone and aldosterone in central angiotensin II-induced hypertension.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Brain; Corticosterone; Cytochrome P-450 CYP11B2; Dose-Response Relationship, Drug; Eplerenone; Fadrozole; Heart Rate; Hypertension; Male; Mineralocorticoid Receptor Antagonists; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptors, Mineralocorticoid; Spironolactone | 2013 |
Role of brain aldosterone and mineralocorticoid receptors in aldosterone-salt hypertension in rats.
Topics: Aldosterone; Animals; Arterial Pressure; Corticosterone; Cytochrome P-450 CYP11B2; Drinking Behavior; Eplerenone; Fadrozole; Hypertension; Male; Mineralocorticoid Receptor Antagonists; Neurons; Paraventricular Hypothalamic Nucleus; Rats; Rats, Wistar; Receptors, Mineralocorticoid; RNA, Messenger; Sodium Chloride; Spironolactone; Subfornical Organ; Supraoptic Nucleus | 2016 |
Aldosterone Synthase Inhibition Improves Glucose Tolerance in Zucker Diabetic Fatty (ZDF) Rats.
Topics: Adrenal Glands; Aldosterone; Animals; Blood Glucose; Body Weight; Cytochrome P-450 CYP11B2; Diabetes Mellitus, Type 2; Disease Models, Animal; Drug Evaluation, Preclinical; Eating; Eplerenone; Fadrozole; Glucose Tolerance Test; Glycated Hemoglobin; Insulin; Insulin Resistance; Insulin Secretion; Liver; Male; Mineralocorticoid Receptor Antagonists; Organ Size; Potassium; Random Allocation; Rats, Zucker; Sodium; Spironolactone; Triglycerides | 2016 |