Page last updated: 2024-09-03

ezogabine and riluzole

ezogabine has been researched along with riluzole in 2 studies

Compound Research Comparison

Studies (ezogabine)	Trials (ezogabine)	Recent Studies (post-2010) (ezogabine)	Studies (riluzole)	Trials (riluzole)	Recent Studies (post-2010) (riluzole)
383	26	241	1,244	153	572

Protein Interaction Comparison

Protein	Taxonomy	riluzole (IC50)
Sodium channel protein type 2 subunit alpha	Rattus norvegicus (Norway rat)	4.73
Cytochrome P450 1A2	Homo sapiens (human)	10
Aldo-keto reductase family 1 member B1	Rattus norvegicus (Norway rat)	1.733
Sodium-dependent noradrenaline transporter	Homo sapiens (human)	1.733

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (50.00)	29.6817
2010's	1 (50.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Su, H; Yaari, Y; Yue, C	1
Ferguson, TA; Franssen, H; Groeneveld, GJ; Heuberger, JAAC; Kovalchuk, MO; Sleutjes, BTHM; van den Berg, LH; Ziagkos, D	1

Trials

1 trial(s) available for ezogabine and riluzole

Article	Year
Acute Effects of Riluzole and Retigabine on Axonal Excitability in Patients With Amyotrophic Lateral Sclerosis: A Randomized, Double-Blind, Placebo-Controlled, Crossover Trial. Clinical pharmacology and therapeutics, 2018, Volume: 104, Issue:6 Topics: Adult; Aged; Amyotrophic Lateral Sclerosis; Axons; Carbamates; Cross-Over Studies; Double-Blind Method; Electromyography; Evoked Potentials, Motor; Excitatory Amino Acid Antagonists; Female; Humans; Male; Middle Aged; Motor Neurons; Netherlands; Neuroprotective Agents; Phenylenediamines; Refractory Period, Electrophysiological; Riluzole; Time Factors; Treatment Outcome	2018

Article

Year

Acute Effects of Riluzole and Retigabine on Axonal Excitability in Patients With Amyotrophic Lateral Sclerosis: A Randomized, Double-Blind, Placebo-Controlled, Crossover Trial.

Clinical pharmacology and therapeutics, 2018, Volume: 104, Issue:6

Topics: Adult; Aged; Amyotrophic Lateral Sclerosis; Axons; Carbamates; Cross-Over Studies; Double-Blind Method; Electromyography; Evoked Potentials, Motor; Excitatory Amino Acid Antagonists; Female; Humans; Male; Middle Aged; Motor Neurons; Netherlands; Neuroprotective Agents; Phenylenediamines; Refractory Period, Electrophysiological; Riluzole; Time Factors; Treatment Outcome

2018

Other Studies

1 other study(ies) available for ezogabine and riluzole

Article	Year
Recruitment of apical dendritic T-type Ca2+ channels by backpropagating spikes underlies de novo intrinsic bursting in hippocampal epileptogenesis. The Journal of physiology, 2007, Apr-15, Volume: 580, Issue:Pt. 2 Topics: Amiloride; Animals; Calcium; Calcium Channels, R-Type; Calcium Channels, T-Type; Carbamates; Dendrites; Male; Nickel; Phenylenediamines; Phorbol 12,13-Dibutyrate; Pyramidal Cells; Rats; Recruitment, Neurophysiological; Riluzole; Sodium; Spider Venoms; Status Epilepticus; Tetrodotoxin	2007

Article

Year

Recruitment of apical dendritic T-type Ca2+ channels by backpropagating spikes underlies de novo intrinsic bursting in hippocampal epileptogenesis.

The Journal of physiology, 2007, Apr-15, Volume: 580, Issue:Pt. 2

Topics: Amiloride; Animals; Calcium; Calcium Channels, R-Type; Calcium Channels, T-Type; Carbamates; Dendrites; Male; Nickel; Phenylenediamines; Phorbol 12,13-Dibutyrate; Pyramidal Cells; Rats; Recruitment, Neurophysiological; Riluzole; Sodium; Spider Venoms; Status Epilepticus; Tetrodotoxin

2007