Page last updated: 2024-09-03

ezogabine and pirenzepine

ezogabine has been researched along with pirenzepine in 2 studies

Compound Research Comparison

Studies (ezogabine)	Trials (ezogabine)	Recent Studies (post-2010) (ezogabine)	Studies (pirenzepine)	Trials (pirenzepine)	Recent Studies (post-2010) (pirenzepine)
383	26	241	3,812	587	140

Protein Interaction Comparison

Protein	Taxonomy	pirenzepine (IC50)
Muscarinic acetylcholine receptor M2	Homo sapiens (human)	0.6891
Muscarinic acetylcholine receptor M4	Homo sapiens (human)	0.5856
Muscarinic acetylcholine receptor M1	Rattus norvegicus (Norway rat)	0.6134
Muscarinic acetylcholine receptor M3	Rattus norvegicus (Norway rat)	0.6222
Muscarinic acetylcholine receptor M4	Rattus norvegicus (Norway rat)	0.6227
Muscarinic acetylcholine receptor M5	Rattus norvegicus (Norway rat)	0.6227
Muscarinic acetylcholine receptor M5	Homo sapiens (human)	0.3406
Muscarinic acetylcholine receptor M2	Rattus norvegicus (Norway rat)	0.6281
Muscarinic acetylcholine receptor M1	Homo sapiens (human)	0.0291
Muscarinic acetylcholine receptor M1	Mus musculus (house mouse)	0.75
Muscarinic acetylcholine receptor M3	Homo sapiens (human)	0.9556
Muscarinic acetylcholine receptor M4	Mus musculus (house mouse)	0.75
Muscarinic acetylcholine receptor M5	Mus musculus (house mouse)	0.75
Muscarinic acetylcholine receptor M3	Mus musculus (house mouse)	0.75
Muscarinic acetylcholine receptor M2	Mus musculus (house mouse)	0.51

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (50.00)	29.6817
2010's	1 (50.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Boehm, S; Drobny, H; Kosenburger, K; Kubista, H; Mahlknecht, P	1
Kaba, H; Takahashi, Y	1

Other Studies

2 other study(ies) available for ezogabine and pirenzepine

Article	Year
Inhibition of transmitter release from rat sympathetic neurons via presynaptic M(1) muscarinic acetylcholine receptors. British journal of pharmacology, 2009, Volume: 156, Issue:8 Topics: Acetylcholine; Action Potentials; Adrenergic Fibers; Animals; Animals, Newborn; Calcium Channel Blockers; Calcium Channels; Calcium Signaling; Carbamates; Cells, Cultured; Diamines; Dose-Response Relationship, Drug; Electric Stimulation; KCNQ Potassium Channels; Muscarinic Agonists; Muscarinic Antagonists; Neural Inhibition; Norepinephrine; omega-Conotoxin GVIA; Oxotremorine; Pertussis Toxin; Phenylenediamines; Pirenzepine; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M1; Receptors, Presynaptic; Superior Cervical Ganglion; Synaptic Transmission; Time Factors; Type C Phospholipases	2009
Muscarinic receptor type 1 (M1) stimulation, probably through KCNQ/Kv7 channel closure, increases spontaneous GABA release at the dendrodendritic synapse in the mouse accessory olfactory bulb. Brain research, 2010, Jun-21, Volume: 1339 Topics: Alkaloids; Animals; Anticonvulsants; Calcium; Calcium Channel Blockers; Calcium Channels, R-Type; Carbachol; Carbamates; Cholinergic Agonists; Dendrites; Diclofenac; Excitatory Amino Acid Antagonists; Furans; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Ion Channel Gating; KCNQ Potassium Channels; Mice; Mice, Inbred BALB C; Muscarinic Antagonists; Naphthalenes; Nimodipine; Olfactory Bulb; Patch-Clamp Techniques; Phenylenediamines; Piperidines; Pirenzepine; Potassium Channel Blockers; Receptor, Muscarinic M1; Receptors, Glutamate; Synapses	2010

Article

Year

Inhibition of transmitter release from rat sympathetic neurons via presynaptic M(1) muscarinic acetylcholine receptors.

British journal of pharmacology, 2009, Volume: 156, Issue:8

Topics: Acetylcholine; Action Potentials; Adrenergic Fibers; Animals; Animals, Newborn; Calcium Channel Blockers; Calcium Channels; Calcium Signaling; Carbamates; Cells, Cultured; Diamines; Dose-Response Relationship, Drug; Electric Stimulation; KCNQ Potassium Channels; Muscarinic Agonists; Muscarinic Antagonists; Neural Inhibition; Norepinephrine; omega-Conotoxin GVIA; Oxotremorine; Pertussis Toxin; Phenylenediamines; Pirenzepine; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M1; Receptors, Presynaptic; Superior Cervical Ganglion; Synaptic Transmission; Time Factors; Type C Phospholipases

2009

Muscarinic receptor type 1 (M1) stimulation, probably through KCNQ/Kv7 channel closure, increases spontaneous GABA release at the dendrodendritic synapse in the mouse accessory olfactory bulb.

Brain research, 2010, Jun-21, Volume: 1339

Topics: Alkaloids; Animals; Anticonvulsants; Calcium; Calcium Channel Blockers; Calcium Channels, R-Type; Carbachol; Carbamates; Cholinergic Agonists; Dendrites; Diclofenac; Excitatory Amino Acid Antagonists; Furans; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Ion Channel Gating; KCNQ Potassium Channels; Mice; Mice, Inbred BALB C; Muscarinic Antagonists; Naphthalenes; Nimodipine; Olfactory Bulb; Patch-Clamp Techniques; Phenylenediamines; Piperidines; Pirenzepine; Potassium Channel Blockers; Receptor, Muscarinic M1; Receptors, Glutamate; Synapses

2010