Page last updated: 2024-09-03

ezogabine and lacosamide

ezogabine has been researched along with lacosamide in 9 studies

Compound Research Comparison

Studies (ezogabine)	Trials (ezogabine)	Recent Studies (post-2010) (ezogabine)	Studies (lacosamide)	Trials (lacosamide)	Recent Studies (post-2010) (lacosamide)
383	26	241	727	90	625

Protein Interaction Comparison

Protein	Taxonomy	ezogabine (IC50)	lacosamide (IC50)
Sodium channel protein type 3 subunit alpha	Rattus norvegicus (Norway rat)		0.415
Sodium channel protein type 9 subunit alpha	Homo sapiens (human)		0.182

Research

Studies (9)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (11.11)	29.6817
2010's	8 (88.89)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Miura, Y	1
Szupera, Z	1
Berry, DJ; Patsalos, PN	1
Mula, M	1
Forsgren, L; Kristian, B; Stefan, F; Wachtmeister, K	1
Citraro, R; Coppola, A; De Sarro, G; Del Gaudio, L; Palleria, C; Russo, E; Striano, S	1
Brodie, MJ	1
Bastin, ML; Cook, AM; Oyler, DR; Smetana, KS	1
Adamczuk, P; Czuczwar, SJ; Florek-Luszczki, M; Kondrat-Wrobel, MW; Luszczki, JJ; Miziak, B; Wroblewska-Luczka, P; Zagaja, M; Zaluska, K	1

Reviews

7 review(s) available for ezogabine and lacosamide

Article	Year
[A new aspect in the research on antiepileptic drugs]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2007, Volume: 129, Issue:2 Topics: Acetamides; Amines; Animals; Anticonvulsants; Benzodiazepines; Carbamates; Cyclohexanecarboxylic Acids; Disease Models, Animal; Drug Design; Gabapentin; gamma-Aminobutyric Acid; Humans; Lacosamide; Levetiracetam; Phenylenediamines; Piracetam; Pregabalin; Pregnanolone; Pyrrolidinones; Triazoles	2007
[New antiepileptic drugs, and therapeutic considerations]. Ideggyogyaszati szemle, 2011, Sep-30, Volume: 64, Issue:9-10 Topics: Acetamides; Anticonvulsants; Carbamates; Dibenzazepines; Epilepsy; Humans; Lacosamide; Phenylenediamines	2011
Pharmacotherapy of the third-generation AEDs: lacosamide, retigabine and eslicarbazepine acetate. Expert opinion on pharmacotherapy, 2012, Volume: 13, Issue:5 Topics: Acetamides; Anticonvulsants; Carbamates; Dibenzazepines; Drug Interactions; Epilepsy; Humans; Lacosamide; Phenylenediamines	2012
Recent and future antiepileptic drugs and their impact on cognition: what can we expect? Expert review of neurotherapeutics, 2012, Volume: 12, Issue:6 Topics: Acetamides; Animals; Anticonvulsants; Carbamates; Cognition; Cognition Disorders; Epilepsy; Forecasting; Humans; Lacosamide; Phenylenediamines	2012
Perspectives on treatment options for mesial temporal lobe epilepsy with hippocampal sclerosis. Expert opinion on pharmacotherapy, 2015, Volume: 16, Issue:15 Topics: Acetamides; Anticonvulsants; Carbamates; Clinical Trials as Topic; Dibenzazepines; Epilepsy, Temporal Lobe; Hippocampus; Humans; Lacosamide; Levetiracetam; Nitriles; Phenylenediamines; Piracetam; Pyridones; Sclerosis; Syndrome	2015
Practical Use of Newer Antiepileptic Drugs as Adjunctive Therapy in Focal Epilepsy. CNS drugs, 2015, Volume: 29, Issue:11 Topics: Acetamides; Adult; Aged; Animals; Anticonvulsants; Carbamates; Dibenzazepines; Drug Resistant Epilepsy; Epilepsies, Partial; Female; Humans; Lacosamide; Male; Middle Aged; Nitriles; Phenylenediamines; Pyridones	2015
Antiepileptic dosing for critically ill adult patients receiving renal replacement therapy. Journal of critical care, 2016, Volume: 36 Topics: Acetamides; Acute Kidney Injury; Amines; Anticonvulsants; Carbamates; Critical Illness; Cyclohexanecarboxylic Acids; Dibenzazepines; Dose-Response Relationship, Drug; Ethosuximide; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lacosamide; Lamotrigine; Levetiracetam; Phenobarbital; Phenylcarbamates; Phenylenediamines; Phenytoin; Piracetam; Propylene Glycols; Renal Dialysis; Renal Replacement Therapy; Seizures; Topiramate; Triazines; Valproic Acid; Zonisamide	2016

Other Studies

2 other study(ies) available for ezogabine and lacosamide

Article	Year
Retigabine as add-on treatment of refractory epilepsy--a cost-utility study in a Swedish setting. Acta neurologica Scandinavica, 2013, Volume: 127, Issue:6 Topics: Acetamides; Adult; Anticonvulsants; Carbamates; Cost-Benefit Analysis; Drug Therapy, Combination; Epilepsies, Partial; Health Care Costs; Humans; Lacosamide; Phenylenediamines; Quality-Adjusted Life Years; Sensitivity and Specificity; Sweden	2013
Beneficial Combination of Lacosamide with Retigabine in Experimental Animals: An Isobolographic Analysis. Pharmacology, 2018, Volume: 101, Issue:1-2 Topics: Acetamides; Animals; Anticonvulsants; Brain; Carbamates; Dose-Response Relationship, Drug; Drug Combinations; Electroshock; Lacosamide; Male; Mice; Phenylenediamines; Psychomotor Performance; Seizures	2018

Article

Year

Retigabine as add-on treatment of refractory epilepsy--a cost-utility study in a Swedish setting.

Acta neurologica Scandinavica, 2013, Volume: 127, Issue:6

Topics: Acetamides; Adult; Anticonvulsants; Carbamates; Cost-Benefit Analysis; Drug Therapy, Combination; Epilepsies, Partial; Health Care Costs; Humans; Lacosamide; Phenylenediamines; Quality-Adjusted Life Years; Sensitivity and Specificity; Sweden

2013

Beneficial Combination of Lacosamide with Retigabine in Experimental Animals: An Isobolographic Analysis.

Pharmacology, 2018, Volume: 101, Issue:1-2

Topics: Acetamides; Animals; Anticonvulsants; Brain; Carbamates; Dose-Response Relationship, Drug; Drug Combinations; Electroshock; Lacosamide; Male; Mice; Phenylenediamines; Psychomotor Performance; Seizures

2018