ezogabine has been researched along with kainic acid in 5 studies
| Studies (ezogabine) | Trials (ezogabine) | Recent Studies (post-2010) (ezogabine) | Studies (kainic acid) | Trials (kainic acid) | Recent Studies (post-2010) (kainic acid) |
|---|---|---|---|---|---|
| 383 | 26 | 241 | 9,540 | 3 | 1,775 |
| Protein | Taxonomy | ezogabine (IC50) | kainic acid (IC50) |
|---|---|---|---|
| Glutamate receptor 1 | Rattus norvegicus (Norway rat) | 4.2857 | |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | 4.2857 | |
| Glutamate receptor 3 | Rattus norvegicus (Norway rat) | 4.2857 | |
| Glutamate receptor 4 | Rattus norvegicus (Norway rat) | 4.2857 | |
| Glutamate receptor ionotropic, kainate 1 | Rattus norvegicus (Norway rat) | 0.0126 | |
| Glutamate receptor ionotropic, kainate 1 | Homo sapiens (human) | 0.077 | |
| Glutamate receptor ionotropic, kainate 2 | Rattus norvegicus (Norway rat) | 0.0126 | |
| Glutamate receptor ionotropic, kainate 3 | Rattus norvegicus (Norway rat) | 0.0126 | |
| Glutamate receptor ionotropic, kainate 4 | Rattus norvegicus (Norway rat) | 0.0126 | |
| Glutamate receptor ionotropic, kainate 2 | Homo sapiens (human) | 0.077 | |
| Glutamate receptor ionotropic, kainate 3 | Homo sapiens (human) | 0.077 | |
| Glutamate receptor ionotropic, kainate 4 | Homo sapiens (human) | 0.077 | |
| Glutamate receptor ionotropic, kainate 5 | Homo sapiens (human) | 0.077 | |
| Glutamate receptor ionotropic, kainate 5 | Rattus norvegicus (Norway rat) | 0.0126 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Netzer, R; Rundfeldt, C | 1 |
| Boehlen, A; Heinemann, U; Kunert, A | 1 |
| Ali, SS; Friedman, LK; Naseer, Z; Slomko, AM; Wongvravit, JP | 1 |
| Greene, DL; Hoshi, N; Kang, S; Kay, HY; Kosenko, A | 1 |
| Deshimaru, M; Hirose, S; Ihara, Y; Ishii, A; Tomonoh, Y; Uchida, T; Zhang, B | 1 |
5 other study(ies) available for ezogabine and kainic acid
| Article | Year |
|---|---|
Investigations into the mechanism of action of the new anticonvulsant retigabine. Interaction with GABAergic and glutamatergic neurotransmission and with voltage gated ion channels.
Topics: Animals; Anticonvulsants; Calcium Channels; Carbamates; Cells, Cultured; Excitatory Amino Acid Agonists; Female; gamma-Aminobutyric Acid; Glutamic Acid; Ion Channel Gating; Kainic Acid; Neurons; Patch-Clamp Techniques; Phenylenediamines; Rats; Sodium Channels; Synaptic Transmission | 2000 |
Effects of XE991, retigabine, losigamone and ZD7288 on kainate-induced theta-like and gamma network oscillations in the rat hippocampus in vitro.
Topics: Animals; Anthracenes; Anticonvulsants; Biological Clocks; CA1 Region, Hippocampal; CA3 Region, Hippocampal; Carbamates; Electrophysiology; Excitatory Amino Acid Agonists; Furans; Kainic Acid; Membrane Potentials; Nerve Net; Neurons; Periodicity; Phenylenediamines; Pyrimidines; Rats; Rats, Wistar | 2009 |
Retigabine calms seizure-induced behavior following status epilepticus.
Topics: Animals; Anticonvulsants; Anxiety; Behavior, Animal; Carbamates; Convulsants; Hippocampus; Hyperkinesis; Kainic Acid; Male; Phenylenediamines; Rats; Rats, Sprague-Dawley; Seizures; Status Epilepticus | 2014 |
M-current preservation contributes to anticonvulsant effects of valproic acid.
Topics: A Kinase Anchor Proteins; Action Potentials; Animals; Anthracenes; Anticonvulsants; Carbamates; Cells, Cultured; Drug Interactions; Female; Hippocampus; Humans; Kainic Acid; KCNQ2 Potassium Channel; Lipoylation; Male; Mice; Mice, Inbred C57BL; Muscarinic Agonists; Muscarinic Antagonists; Neurons; Phenylenediamines; Phosphorylation; Potassium Channel Blockers; Protein Processing, Post-Translational; Rats; Receptor, Muscarinic M1; Recombinant Fusion Proteins; Seizures; Signal Transduction; Superior Cervical Ganglion; Valproic Acid | 2015 |
Retigabine, a Kv7.2/Kv7.3-Channel Opener, Attenuates Drug-Induced Seizures in Knock-In Mice Harboring Kcnq2 Mutations.
Topics: Animals; Carbamates; Gene Knock-In Techniques; Humans; Ion Channel Gating; Kainic Acid; KCNQ2 Potassium Channel; KCNQ3 Potassium Channel; Mice; Models, Molecular; Mutation; Phenylenediamines; Protein Structure, Tertiary; Seizures | 2016 |