ezogabine has been researched along with glutamic acid in 5 studies
| Studies (ezogabine) | Trials (ezogabine) | Recent Studies (post-2010) (ezogabine) | Studies (glutamic acid) | Trials (glutamic acid) | Recent Studies (post-2010) (glutamic acid) |
|---|---|---|---|---|---|
| 383 | 26 | 241 | 41,757 | 452 | 12,876 |
| Protein | Taxonomy | ezogabine (IC50) | glutamic acid (IC50) |
|---|---|---|---|
| Chain A, GLUTAMATE RECEPTOR SUBUNIT 2 | Rattus norvegicus (Norway rat) | 0.821 | |
| Chain A, Glutamate Receptor Subunit 2 | Rattus norvegicus (Norway rat) | 0.821 | |
| Chain B, Glutamate Receptor Subunit 2 | Rattus norvegicus (Norway rat) | 0.821 | |
| Metabotropic glutamate receptor 8 | Homo sapiens (human) | 0.0057 | |
| Glutamate receptor ionotropic, NMDA 2D | Homo sapiens (human) | 0.07 | |
| Glutamate receptor ionotropic, NMDA 3B | Homo sapiens (human) | 0.07 | |
| Glutamate receptor 1 | Rattus norvegicus (Norway rat) | 0.5885 | |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | 0.5885 | |
| Glutamate receptor 3 | Rattus norvegicus (Norway rat) | 0.5885 | |
| Glutamate receptor 4 | Rattus norvegicus (Norway rat) | 0.5885 | |
| Glutamate receptor ionotropic, kainate 1 | Rattus norvegicus (Norway rat) | 0.38 | |
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | 0.1533 | |
| Glutamate receptor ionotropic, kainate 2 | Rattus norvegicus (Norway rat) | 0.38 | |
| Glutamate receptor 1 | Homo sapiens (human) | 0.613 | |
| Glutamate receptor 2 | Homo sapiens (human) | 0.613 | |
| Glutamate receptor 3 | Homo sapiens (human) | 0.613 | |
| Glutamate receptor ionotropic, kainate 3 | Rattus norvegicus (Norway rat) | 0.38 | |
| Excitatory amino acid transporter 1 | Homo sapiens (human) | 207 | |
| Glutamate receptor 4 | Homo sapiens (human) | 0.613 | |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | 0.1533 | |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | 0.1533 | |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | 0.1533 | |
| Glutamate receptor ionotropic, kainate 4 | Rattus norvegicus (Norway rat) | 0.38 | |
| Glutamate receptor ionotropic, NMDA 1 | Homo sapiens (human) | 0.07 | |
| Glutamate receptor ionotropic, NMDA 2A | Homo sapiens (human) | 0.07 | |
| Glutamate receptor ionotropic, NMDA 2B | Homo sapiens (human) | 0.07 | |
| Glutamate receptor ionotropic, NMDA 2C | Homo sapiens (human) | 0.07 | |
| Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | 0.1533 | |
| Glutamate receptor ionotropic, kainate 5 | Rattus norvegicus (Norway rat) | 0.38 | |
| Glutamate receptor ionotropic, NMDA 3A | Homo sapiens (human) | 0.07 | |
| Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | 0.1533 | |
| Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | 0.1533 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (80.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Evert, BO; Klockgether, T; Kovar, KA; Rundfeldt, C; Schulz, JB; Seyfried, J; Wüllner, U | 1 |
| Brodie, MJ; Butler, E; Forrest, G; Rundfeldt, C; Sills, GJ; Thompson, GG | 1 |
| Netzer, R; Rundfeldt, C | 1 |
| Mora, G; Tapia, R | 1 |
| Diao, Y; Li, J; Luo, Y; Sun, W; Yan, W; Yin, Y | 1 |
5 other study(ies) available for ezogabine and glutamic acid
| Article | Year |
|---|---|
Flupirtine and retigabine prevent L-glutamate toxicity in rat pheochromocytoma PC 12 cells.
Topics: Aminopyridines; Analgesics; Animals; Antidepressive Agents; Carbamates; Cell Death; Clorgyline; Culture Media; Cystine; Dopamine Agents; Excitatory Amino Acid Antagonists; Glutamic Acid; Glutathione; Levodopa; Monoamine Oxidase; Monoamine Oxidase Inhibitors; PC12 Cells; Phenylenediamines; Rats; Reactive Oxygen Species; Receptors, N-Methyl-D-Aspartate | 2000 |
A neurochemical study of the novel antiepileptic drug retigabine in mouse brain.
Topics: 4-Aminobutyrate Transaminase; Animals; Anticonvulsants; Brain Chemistry; Carbamates; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamic Acid; Glutamine; Male; Mice; Mice, Inbred ICR; Phenylenediamines | 2000 |
Investigations into the mechanism of action of the new anticonvulsant retigabine. Interaction with GABAergic and glutamatergic neurotransmission and with voltage gated ion channels.
Topics: Animals; Anticonvulsants; Calcium Channels; Carbamates; Cells, Cultured; Excitatory Amino Acid Agonists; Female; gamma-Aminobutyric Acid; Glutamic Acid; Ion Channel Gating; Kainic Acid; Neurons; Patch-Clamp Techniques; Phenylenediamines; Rats; Sodium Channels; Synaptic Transmission | 2000 |
Effects of retigabine on the neurodegeneration and extracellular glutamate changes induced by 4-aminopyridine in rat hippocampus in vivo.
Topics: 4-Aminopyridine; Animals; Anticonvulsants; Carbamates; Drug Interactions; Electroencephalography; Extracellular Space; Glutamic Acid; Hippocampus; Male; Microdialysis; Neurodegenerative Diseases; Phenylenediamines; Rats; Rats, Wistar | 2005 |
The dual role of KCNQ/M channels upon OGD or OGD/R insults in cultured cortical neurons of mice: Timing is crucial in targeting M-channels against ischemic injur ies.
Topics: Animals; Carbamates; Female; Glucose; Glutamic Acid; KCNQ Potassium Channels; Male; Membrane Potential, Mitochondrial; Mice; Mice, Inbred C57BL; Neurons; Oxygen; Phenylenediamines; Reperfusion Injury | 2019 |