ezogabine has been researched along with carbachol in 3 studies
| Studies (ezogabine) | Trials (ezogabine) | Recent Studies (post-2010) (ezogabine) | Studies (carbachol) | Trials (carbachol) | Recent Studies (post-2010) (carbachol) |
|---|---|---|---|---|---|
| 383 | 26 | 241 | 13,918 | 81 | 968 |
| Protein | Taxonomy | ezogabine (IC50) | carbachol (IC50) |
|---|---|---|---|
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | 0.7849 | |
| Muscarinic acetylcholine receptor M4 | Homo sapiens (human) | 2.0626 | |
| Muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | 3.4134 | |
| Muscarinic acetylcholine receptor M3 | Rattus norvegicus (Norway rat) | 2.9961 | |
| Muscarinic acetylcholine receptor M4 | Rattus norvegicus (Norway rat) | 2.535 | |
| Muscarinic acetylcholine receptor M5 | Rattus norvegicus (Norway rat) | 2.9961 | |
| Muscarinic acetylcholine receptor M2 | Rattus norvegicus (Norway rat) | 2.6638 | |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | 4.849 | |
| Muscarinic acetylcholine receptor M3 | Homo sapiens (human) | 4.99 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kaba, H; Takahashi, Y | 1 |
| Rode, F; Rønn, LC; Sheykhzade, M; Svalø, J | 1 |
| Davies, KP; Fu, S; Melman, A; Tar, MT; Wang, Y | 1 |
3 other study(ies) available for ezogabine and carbachol
| Article | Year |
|---|---|
Muscarinic receptor type 1 (M1) stimulation, probably through KCNQ/Kv7 channel closure, increases spontaneous GABA release at the dendrodendritic synapse in the mouse accessory olfactory bulb.
Topics: Alkaloids; Animals; Anticonvulsants; Calcium; Calcium Channel Blockers; Calcium Channels, R-Type; Carbachol; Carbamates; Cholinergic Agonists; Dendrites; Diclofenac; Excitatory Amino Acid Antagonists; Furans; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Ion Channel Gating; KCNQ Potassium Channels; Mice; Mice, Inbred BALB C; Muscarinic Antagonists; Naphthalenes; Nimodipine; Olfactory Bulb; Patch-Clamp Techniques; Phenylenediamines; Piperidines; Pirenzepine; Potassium Channel Blockers; Receptor, Muscarinic M1; Receptors, Glutamate; Synapses | 2010 |
Functional effects of the KCNQ modulators retigabine and XE991 in the rat urinary bladder.
Topics: Animals; Anthracenes; Anticonvulsants; Carbachol; Carbamates; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; In Vitro Techniques; KCNQ Potassium Channels; Muscle Contraction; Phenylenediamines; Potassium Channel Blockers; Potassium Chloride; Rats; Rats, Sprague-Dawley; Urinary Bladder | 2010 |
Diabetes attenuates urothelial modulation of detrusor contractility and spontaneous activity.
Topics: Animals; Anthracenes; Carbachol; Carbamates; Cholinergic Agonists; Diabetes Mellitus, Experimental; KCNQ Potassium Channels; Large-Conductance Calcium-Activated Potassium Channels; Male; Membrane Transport Modulators; Muscle Contraction; Peptides; Phenylenediamines; Rats; Rats, Inbred F344; Tetraethylammonium; Urinary Bladder; Urothelium | 2014 |