Page last updated: 2024-09-03

ezogabine and capsaicin

ezogabine has been researched along with capsaicin in 4 studies

Compound Research Comparison

Studies
(ezogabine)
Trials
(ezogabine)
Recent Studies (post-2010)
(ezogabine)
Studies
(capsaicin)
Trials
(capsaicin)
Recent Studies (post-2010) (capsaicin)
3832624111,2386613,410

Protein Interaction Comparison

ProteinTaxonomyezogabine (IC50)capsaicin (IC50)
Transient receptor potential cation channel subfamily V member 1Rattus norvegicus (Norway rat)0.019
Lysine-specific histone demethylase 1AHomo sapiens (human)0.6
Bile salt export pumpHomo sapiens (human)10
Cytochrome P450 1A2Homo sapiens (human)3
Prostaglandin G/H synthase 1Homo sapiens (human)2.6755
Transient receptor potential cation channel subfamily V member 1Homo sapiens (human)0.008

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's2 (50.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Gao, J; Guo, Y; Hu, X; Huang, H; Jin, Z; Li, Z; Liu, Z; Wang, K; Wang, Y; Zhang, L; Zhong, Y; Zong, X1
Fujiyoshi, M; Hayashi, E; Hirano, K; Kinoshita, M; Kuratani, K; Tashiro, N1
Hansen, HH; Munro, G; Rode, F; Rønn, LC; Sheykhzade, M; Svalø, J1
Bi, Y; Bian, X; Cao, X; Chen, H; Su, J; Wang, K1

Other Studies

4 other study(ies) available for ezogabine and capsaicin

ArticleYear
Optimization of 4-arylthiophene-3-carboxylic acid derivatives as inhibitors of ANO1: Lead optimization studies toward their analgesic efficacy for inflammatory pain.
    European journal of medicinal chemistry, 2022, Jul-05, Volume: 237

    Topics: Analgesics; Animals; Anoctamin-1; Carboxylic Acids; HEK293 Cells; Humans; Hyperalgesia; Mice; Neoplasm Proteins; Pain

2022
Kv7.2-7.5 voltage-gated potassium channel (KCNQ2-5) opener, retigabine, reduces capsaicin-induced visceral pain in mice.
    Neuroscience letters, 2007, Feb-14, Volume: 413, Issue:2

    Topics: Animals; Anticonvulsants; Capsaicin; Carbamates; Colon; KCNQ2 Potassium Channel; Male; Mice; Mice, Inbred ICR; Nociceptors; Pain; Pain Measurement; Pain Threshold; Phenylenediamines; Reaction Time; Sensory Receptor Cells; Visceral Afferents

2007
Kv 7 positive modulators reduce detrusor overactivity and increase bladder capacity in rats.
    Basic & clinical pharmacology & toxicology, 2012, Volume: 110, Issue:2

    Topics: Animals; Anthracenes; Capsaicin; Carbamates; Female; KCNQ Potassium Channels; Phenylenediamines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Urinary Bladder; Urinary Bladder, Overactive

2012
Visceral hyperalgesia induced by forebrain-specific suppression of native Kv7/KCNQ/M-current in mice.
    Molecular pain, 2011, Oct-26, Volume: 7

    Topics: Animals; Anthracenes; Capsaicin; Carbamates; Hyperalgesia; KCNQ2 Potassium Channel; Magnesium Sulfate; Mice; Mice, Transgenic; Phenylenediamines; Prosencephalon; Proto-Oncogene Proteins c-fos; Somatosensory Cortex; Visceral Pain

2011