ezlopitant has been researched along with troleandomycin in 1 studies
| Studies (ezlopitant) | Trials (ezlopitant) | Recent Studies (post-2010) (ezlopitant) | Studies (troleandomycin) | Trials (troleandomycin) | Recent Studies (post-2010) (troleandomycin) |
|---|---|---|---|---|---|
| 22 | 2 | 1 | 569 | 26 | 23 |
| Protein | Taxonomy | ezlopitant (IC50) | troleandomycin (IC50) |
|---|---|---|---|
| Cytochrome P450 3A4 | Homo sapiens (human) | 7.9983 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Obach, RS | 1 |
1 other study(ies) available for ezlopitant and troleandomycin
| Article | Year |
|---|---|
Metabolism of ezlopitant, a nonpeptidic substance P receptor antagonist, in liver microsomes: enzyme kinetics, cytochrome P450 isoform identity, and in vitro-in vivo correlation.
Topics: Animals; Benzylamines; Bridged Bicyclo Compounds, Heterocyclic; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dogs; Enzyme Inhibitors; Guinea Pigs; Haplorhini; Humans; Isoenzymes; Ketoconazole; Kinetics; Metabolic Clearance Rate; Microsomes, Liver; Neurokinin-1 Receptor Antagonists; Quinidine; Rats; Species Specificity; Sulfaphenazole; Tritium; Troleandomycin | 2000 |