Page last updated: 2024-09-05

ezlopitant and substance p

ezlopitant has been researched along with substance p in 3 studies

Compound Research Comparison

Studies (ezlopitant)	Trials (ezlopitant)	Recent Studies (post-2010) (ezlopitant)	Studies (substance p)	Trials (substance p)	Recent Studies (post-2010) (substance p)
22	2	1	17,289	277	2,010

Protein Interaction Comparison

Protein	Taxonomy	substance p (IC50)
Substance-P receptor	Rattus norvegicus (Norway rat)	0.0005
Substance-K receptor	Rattus norvegicus (Norway rat)	0.2
Substance-K receptor	Homo sapiens (human)	0.2455
Substance-P receptor	Homo sapiens (human)	0.0011
Neuromedin-K receptor	Homo sapiens (human)	0.125
Substance-K receptor	Mesocricetus auratus (golden hamster)	0.148

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	2 (66.67)	29.6817
2010's	1 (33.33)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Russell, IJ	1
Kamel, AM; Massefski, WW; Zandi, KS	1
Eggan, BL; McCallum, SE	1

Reviews

1 review(s) available for ezlopitant and substance p

Article	Year
The promise of substance P inhibitors in fibromyalgia. Rheumatic diseases clinics of North America, 2002, Volume: 28, Issue:2 Topics: Benzene Derivatives; Fibromyalgia; Humans; Neurokinin-1 Receptor Antagonists; Receptors, Neurokinin-1; Substance P	2002

Other Studies

2 other study(ies) available for ezlopitant and substance p

Article	Year
Identification of the degradation product of ezlopitant, a non-peptidic substance P antagonist receptor, by hydrogen deuterium exchange, electrospray ionization tandem mass spectrometry (ESI/MS/MS) and nuclear magnetic resonance (NMR) spectroscopy. Journal of pharmaceutical and biomedical analysis, 2003, Apr-10, Volume: 31, Issue:6 Topics: Benzylamines; Bridged Bicyclo Compounds, Heterocyclic; Deuterium; Magnetic Resonance Spectroscopy; Protons; Spectrometry, Mass, Electrospray Ionization; Substance P	2003
α3β4 nicotinic receptors in the medial habenula and substance P transmission in the interpeduncular nucleus modulate nicotine sensitization. Behavioural brain research, 2017, 01-01, Volume: 316 Topics: Analysis of Variance; Animals; Benzylamines; Bridged Bicyclo Compounds, Heterocyclic; Cholinergic Antagonists; Chromatography, High Pressure Liquid; Dihydro-beta-Erythroidine; Dopamine; Dose-Response Relationship, Drug; Female; Interpeduncular Nucleus; Microdialysis; Nicotine; Nicotinic Agonists; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Signal Transduction; Substance P	2017

Article

Year

Identification of the degradation product of ezlopitant, a non-peptidic substance P antagonist receptor, by hydrogen deuterium exchange, electrospray ionization tandem mass spectrometry (ESI/MS/MS) and nuclear magnetic resonance (NMR) spectroscopy.

Journal of pharmaceutical and biomedical analysis, 2003, Apr-10, Volume: 31, Issue:6

Topics: Benzylamines; Bridged Bicyclo Compounds, Heterocyclic; Deuterium; Magnetic Resonance Spectroscopy; Protons; Spectrometry, Mass, Electrospray Ionization; Substance P

2003

α3β4 nicotinic receptors in the medial habenula and substance P transmission in the interpeduncular nucleus modulate nicotine sensitization.

Behavioural brain research, 2017, 01-01, Volume: 316

Topics: Analysis of Variance; Animals; Benzylamines; Bridged Bicyclo Compounds, Heterocyclic; Cholinergic Antagonists; Chromatography, High Pressure Liquid; Dihydro-beta-Erythroidine; Dopamine; Dose-Response Relationship, Drug; Female; Interpeduncular Nucleus; Microdialysis; Nicotine; Nicotinic Agonists; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Signal Transduction; Substance P

2017