Page last updated: 2024-09-05

ezlopitant and morphine

ezlopitant has been researched along with morphine in 2 studies

Compound Research Comparison

Studies
(ezlopitant)
Trials
(ezlopitant)
Recent Studies (post-2010)
(ezlopitant)
Studies
(morphine)
Trials
(morphine)
Recent Studies (post-2010) (morphine)
222144,2705,2008,695

Protein Interaction Comparison

ProteinTaxonomyezlopitant (IC50)morphine (IC50)
Delta-type opioid receptorMus musculus (house mouse)0.2939
Delta-type opioid receptorRattus norvegicus (Norway rat)0.2278
Kappa-type opioid receptorMus musculus (house mouse)0.0828
Mu-type opioid receptorRattus norvegicus (Norway rat)0.0385
Kappa-type opioid receptorRattus norvegicus (Norway rat)0.0545
Mu-type opioid receptorHomo sapiens (human)0.122
Delta-type opioid receptorHomo sapiens (human)0.1199
Kappa-type opioid receptorCavia porcellus (domestic guinea pig)0.9308
Kappa-type opioid receptorHomo sapiens (human)0.655
Mu-type opioid receptorMus musculus (house mouse)0.3305
Mu-type opioid receptorCavia porcellus (domestic guinea pig)0.202
Beta-2 adrenergic receptorCavia porcellus (domestic guinea pig)0.25

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Honda, M; Ono, H; Tanabe, M; Yamamoto, S1
Adams, C; Bilsky, EJ; Cormier, J; Dunbar, C; Mercer, H; Negus, SS; Stevenson, GW1

Other Studies

2 other study(ies) available for ezlopitant and morphine

ArticleYear
Spinal ventral root after-discharges as a pain index: involvement of NK-1 and NMDA receptors.
    Brain research, 2006, Apr-12, Volume: 1082, Issue:1

    Topics: Action Potentials; Analysis of Variance; Animals; Benzylamines; Bridged Bicyclo Compounds, Heterocyclic; Diterpenes; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Excitatory Amino Acid Antagonists; Ketamine; Male; Mephenesin; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Neurotoxins; Pain; Pain Measurement; Physical Stimulation; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Receptors, Neurokinin-1; Spinal Nerve Roots; Time Factors

2006
Targeting pain-depressed behaviors in preclinical assays of pain and analgesia: drug effects on acetic acid-depressed locomotor activity in ICR mice.
    Life sciences, 2009, Aug-12, Volume: 85, Issue:7-8

    Topics: Acetic Acid; Analgesia; Analgesics; Animals; Behavior, Animal; Benzene Derivatives; Caffeine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Haloperidol; Male; Mice; Mice, Inbred ICR; Morphine; Motor Activity; Pain; Pain Measurement

2009