Page last updated: 2024-09-05

ezlopitant and deuterium

ezlopitant has been researched along with deuterium in 2 studies

Compound Research Comparison

Studies (ezlopitant)	Trials (ezlopitant)	Recent Studies (post-2010) (ezlopitant)	Studies (deuterium)	Trials (deuterium)	Recent Studies (post-2010) (deuterium)
22	2	1	13,104	217	2,527

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	2 (100.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Obach, RS	1
Kamel, AM; Massefski, WW; Zandi, KS	1

Other Studies

2 other study(ies) available for ezlopitant and deuterium

Article	Year
Mechanism of cytochrome P4503A4- and 2D6-catalyzed dehydrogenation of ezlopitant as probed with isotope effects using five deuterated analogs. Drug metabolism and disposition: the biological fate of chemicals, 2001, Volume: 29, Issue:12 Topics: Benzylamines; Bridged Bicyclo Compounds, Heterocyclic; Catalysis; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Deuterium; Isotope Labeling; Kinetics; Mixed Function Oxygenases; Neurokinin-1 Receptor Antagonists; Recombinant Proteins	2001
Identification of the degradation product of ezlopitant, a non-peptidic substance P antagonist receptor, by hydrogen deuterium exchange, electrospray ionization tandem mass spectrometry (ESI/MS/MS) and nuclear magnetic resonance (NMR) spectroscopy. Journal of pharmaceutical and biomedical analysis, 2003, Apr-10, Volume: 31, Issue:6 Topics: Benzylamines; Bridged Bicyclo Compounds, Heterocyclic; Deuterium; Magnetic Resonance Spectroscopy; Protons; Spectrometry, Mass, Electrospray Ionization; Substance P	2003

Article

Year

Mechanism of cytochrome P4503A4- and 2D6-catalyzed dehydrogenation of ezlopitant as probed with isotope effects using five deuterated analogs.

Drug metabolism and disposition: the biological fate of chemicals, 2001, Volume: 29, Issue:12

Topics: Benzylamines; Bridged Bicyclo Compounds, Heterocyclic; Catalysis; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Deuterium; Isotope Labeling; Kinetics; Mixed Function Oxygenases; Neurokinin-1 Receptor Antagonists; Recombinant Proteins

2001

Identification of the degradation product of ezlopitant, a non-peptidic substance P antagonist receptor, by hydrogen deuterium exchange, electrospray ionization tandem mass spectrometry (ESI/MS/MS) and nuclear magnetic resonance (NMR) spectroscopy.

Journal of pharmaceutical and biomedical analysis, 2003, Apr-10, Volume: 31, Issue:6

Topics: Benzylamines; Bridged Bicyclo Compounds, Heterocyclic; Deuterium; Magnetic Resonance Spectroscopy; Protons; Spectrometry, Mass, Electrospray Ionization; Substance P

2003