Page last updated: 2024-09-04

ezetimibe and posaconazole

ezetimibe has been researched along with posaconazole in 3 studies

Compound Research Comparison

Studies
(ezetimibe)
Trials
(ezetimibe)
Recent Studies (post-2010)
(ezetimibe)
Studies
(posaconazole)
Trials
(posaconazole)
Recent Studies (post-2010) (posaconazole)
2,4845631,4651,5751031,014

Protein Interaction Comparison

ProteinTaxonomyezetimibe (IC50)posaconazole (IC50)
Bile salt export pumpHomo sapiens (human)8.1
Steroid 17-alpha-hydroxylase/17,20 lyaseHomo sapiens (human)0.921
Cytochrome P450 3A4Homo sapiens (human)0.2458
AromataseHomo sapiens (human)8.4
Cytochrome P450 2C9 Homo sapiens (human)7.2
Cytochrome P450 11B1, mitochondrialHomo sapiens (human)0.31
Cytochrome P450 11B2, mitochondrialHomo sapiens (human)0.021
Sterol 14-alpha demethylaseTrypanosoma cruzi strain CL Brener0.464
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)6

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Chellappan, DK; Collet, TA; Dighe, SN; Dua, K; Ekwudu, O; Katavic, PL1

Reviews

2 review(s) available for ezetimibe and posaconazole

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Recent update on anti-dengue drug discovery.
    European journal of medicinal chemistry, 2019, Aug-15, Volume: 176

    Topics: Animals; Antiviral Agents; Biological Products; Cell Line, Tumor; Dengue Virus; Drug Discovery; Humans; Serine Proteinase Inhibitors; Viral Nonstructural Proteins; Virus Replication

2019

Other Studies

1 other study(ies) available for ezetimibe and posaconazole

ArticleYear
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013