Page last updated: 2024-09-04

ezetimibe and phytosterols

ezetimibe has been researched along with phytosterols in 63 studies

Compound Research Comparison

Studies
(ezetimibe)
Trials
(ezetimibe)
Recent Studies (post-2010)
(ezetimibe)
Studies
(phytosterols)
Trials
(phytosterols)
Recent Studies (post-2010) (phytosterols)
2,4845631,4653,9003691,814

Research

Studies (63)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's20 (31.75)29.6817
2010's38 (60.32)24.3611
2020's5 (7.94)2.80

Authors

AuthorsStudies
Sudhop, T; von Bergmann, K1
Gylling, H; Miettinen, TA; Vanhanen, H1
Lehmann, R; Ramsey, LA1
Kane, J; Kwiterovich, P; Lütjohann, D; Musliner, T; Musser, B; Patel, SB; Salen, G; Stein, P; von Bergmann, K1
Scheen, AJ1
Batta, AK; Bollineni, JS; Salen, G; Shefer, S; Xu, G1
Lütjohann, D; Sudhop, T; von Bergmann, K2
Cohen, JC; Hobbs, HH; Lütjohann, D; von Bergmann, K; Yu, L1
Jakulj, L; Kastelein, JJ; Sudhop, T; Trip, MD; Vissers, MN; von Bergmann, K1
Arreaza, MG; Bayne, ML; Deutsch, P; Devlin, DJ; Karnoub, MC; Monks, SA; Palmisano, J; Plump, AS; Qiu, P; Sachs, AB; Schadt, EE; Severino, ME; Simon, JS1
Radermecker, RP; Scheen, AJ1
Grube, M; Kroemer, HK; Oswald, S; Siegmund, W; Weitschies, W; Westrup, S1
Davidson, MH; Robinson, JG1
Burnett, JR; Huff, MW1
Giessmann, T; Luetjohann, D; Oswald, S; Rosskopf, D; Siegmund, W; Wegner, D; Weitschies, W1
Márk, L; Paragh, G1
Assmann, G; Gutkin, SW; Kannenberg, F; Musliner, TA; Ramey, DR; Veltri, EP1
Filippatos, TD; Mikhailidis, DP1
Groen, AK; Hutten, BA; Jakulj, L; Kastelein, JJ; Lutjohann, D; Veltri, EP; Vissers, MN1
Gupta, A; Guyomard, V; Myint, PK; Rehman, HU; Zaman, MJ1
Masuda, D; Nakagawa-Toyama, Y; Nishida, M; Ohama, T; Tsubakio-Yamamoto, K; Yamashita, S1
Ishibashi, S; Kotani, K; Miyamoto, M; Nagasaka, S; Okada, K; Osuga, J; Yagyu, H1
Betters, JL; Jia, L; Yu, L1
Hattori, S; Hattori, Y1
Doggrell, SA1
Hu, FB1
Lefevre, M; Lin, X; Ma, L; Ostlund, RE; Racette, SB; Spearie, CA; Steger-May, K1
Borges, NC; Fonseca, FA; Helfenstein, T; Izar, MC; Kasmas, SH; Moreira, FT; Moreno, RA; Ramos, SC; Rezende, VM; Silva, FC1
Blum, D; Chaput, E; Derks, M; Kallend, D; Niesor, EJ; Staempfli, A1
Endo, T; Fukui, K; Himeno, H; Iwahashi, N; Iwasawa, Y; Kimura, K; Kobayashi, S; Mochida, Y; Morita, Y; Okada, K; Sawada, R; Shigemasa, T; Shimizu, M; Shimizu, T; Uchino, K; Umemura, S; Wada, A1
Darlington, JW; Gershkovich, P; Lee, SD; Wasan, KM1
Genser, B; März, W; Nestel, P; Silbernagel, G1
Patel, SB; Solca, C; Tint, GS1
Aguirre, AC; Amaral, JB; Barbosa, SP; Bianco, HT; Fonseca, FA; França, CN; Izar, MC; Lins, LC; Matos, LN; Santana, JM1
Fukushima, Y; Higuchi, K; Hirayama, S; Inoue, M; Kamimura, Y; Miida, T; Nakagawa, S; Nishioka, E; Ohmura, H; Seino, U; Soda, S; Ueno, T; Yamato, S1
Jones, PJ; Myrie, SB; Othman, RA1
Browne, RW; Griffin, JD; Harding, SV; Jones, PJ; Ramprasath, V; Rideout, TC1
Baumgartner, I; März, W; Silbernagel, G; Wanner, C1
Gürsel, T; Kaya, Z; Niu, DM; Tekin, A; Yorulmaz, A1
Blanco-Vaca, F; Cedó, L; Escolà-Gil, JC; Julve, J; Martín-Campos, JM; Quesada, H1
Levesque, MC; Liang, KP; Mock, GD; Modi, SR; Ruiz, XD1
Cofán, M; Forga, MT; Larrousse, M; Leyes, P; Martínez, E; Pérez-Heras, AM; Ros, E; Trabal, J1
AbuMweis, SS; Frohlich, J; Jones, PJ; Marinangeli, CP1
Jones, PJ; Merkens, LS; Mymin, D; Myrie, SB; Othman, RA; Roullet, JB; Steiner, RD1
Kanno, K; Kishikawa, N; Mizooka, M; Sugiyama, A; Tazuma, S; Yokobayashi, K1
Chen, X; Gong, Z; Hao, Y; Li, Y; Liu, J; Qi, Y; Qin, L; Sun, J; Wang, M; Wang, W; Wang, Y; Xie, W; Zhang, Q; Zhao, D; Zhao, F1
Awata, T; Inoue, I; Katayama, S; Murakoshi, T; Nakano, T; Ono, H; Takenaka, Y1
Baila-Rueda, L; Cenarro, A; Civeira, F1
Baena, CP; da Costa, AB; Faria-Neto, JR; Fedato, RA; Gomes, GB; Guarita-Souza, LC; Olandoski, M; Shigueoka, LS; Zazula, AD1
Jones, PJH; Mymin, D; Myrie, SB; Othman, RA; Roullet, JB; Steiner, RD1
Blanco-Vaca, F; Cedó, L; Escolà-Gil, JC1
Bartuli, A; Bertolini, S; Bruzzi, P; Buonuomo, PS; Calandra, S; Cortese, C; Iughetti, L; Papadia, F; Pisciotta, L; Rabacchi, C; Tummolo, A1
DeBarber, AE; Jones, PJH; Mymin, D; Myrie, SB; Othman, RA; Roullet, JB; Steiner, RD1
Bastida, JM; Benito, R; Díez-Campelo, M; Girós, M; González-Porras, JR; Hernández-Rivas, JM; Hernández-Sánchez, JM; Hortal, A; Janusz, K; Lozano, ML; Marcellini, S; Rivera, J1
Aoyama, K; Ichikawa, T; Kobayashi, K; Nakane, T; Sugita, K; Toda, T; Yagasaki, H1
Dembinski, T; Hatch, GM; Mymin, D; Salen, G; Triggs-Raine, B; Waggoner, DJ1
Dateki, S; Ikeda, K; Kashimada, K; Komiya, C; Mishima, H; Nakano, Y; Ogawa, Y; Shiba, K; Shimizu, H; Tsujimoto, K; Yamada, T; Yoshiura, KI1
Hirano, S; Kawashiri, MA; Nomura, A; Tada, H; Takenaga, M; Tanaka, H; Watanabe, Y1
Hamasaki, A; Hasebe, M; Honjo, S; Iwasaki, K; Iwasaki, Y; Keidai, Y1
Christian Schulze, P; Friedrichs, S; Kerksiek, A; Lütjohann, D; Möbius-Winkler, S; Otto, S; Pörner, TC; Weingärtner, O1
Akiyama, Y; Fujii, H; Harada-Shiba, M; Ishibashi, Y; Ishida, T; Ishigaki, Y; Kabata, D; Kihara, Y; Kotani, K; Kurisu, S; Masuda, D; Matoba, T; Matsuki, K; Matsumura, T; Mori, K; Nakagami, T; Nakazato, M; Shoji, T; Taniuchi, S; Ueno, H; Yamashita, S; Yoshida, H1

Reviews

21 review(s) available for ezetimibe and phytosterols

ArticleYear
Cholesterol absorption inhibitors for the treatment of hypercholesterolaemia.
    Drugs, 2002, Volume: 62, Issue:16

    Topics: Anticholesteremic Agents; Azetidines; Cholesterol; Clinical Trials as Topic; Drug Synergism; Ezetimibe; Humans; Hypercholesterolemia; Phytosterols; Sterol O-Acyltransferase; Sterol O-Acyltransferase 2; Structure-Activity Relationship

2002
[Combination therapy of hypercholesterolemia].
    Duodecim; laaketieteellinen aikakauskirja, 2002, Volume: 118, Issue:19

    Topics: Anticholesteremic Agents; Azetidines; Cholesterol, LDL; Cholestyramine Resin; Combined Modality Therapy; Drug Therapy, Combination; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Margarine; Phytosterols

2002
Cholesterol absorption inhibitors: a closer look.
    Advance for nurse practitioners, 2003, Volume: 11, Issue:11

    Topics: Anticholesteremic Agents; Azetidines; Drug Therapy, Combination; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Patient Selection; Phytosterols; Treatment Outcome

2003
Sterol transporters: targets of natural sterols and new lipid lowering drugs.
    Pharmacology & therapeutics, 2005, Volume: 105, Issue:3

    Topics: Animals; Annexins; Anticholesteremic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 5; ATP Binding Cassette Transporter, Subfamily G, Member 8; ATP-Binding Cassette Transporters; Azetidines; Cholesterol; Ezetimibe; Humans; Lipoproteins; Phytosterols

2005
Cholesterol and plant sterol absorption: recent insights.
    The American journal of cardiology, 2005, Jul-04, Volume: 96, Issue:1A

    Topics: Absorption; Anticholesteremic Agents; ATP-Binding Cassette Transporters; Azetidines; Cholesterol; Diet; Ezetimibe; Humans; Hypercholesterolemia; Membrane Proteins; Membrane Transport Proteins; Microvilli; Phytosterols; Proteins

2005
Combination therapy with ezetimibe and simvastatin to achieve aggressive LDL reduction.
    Expert review of cardiovascular therapy, 2006, Volume: 4, Issue:4

    Topics: Anticholesteremic Agents; Atorvastatin; Azetidines; C-Reactive Protein; Cardiovascular Diseases; Drug Therapy, Combination; Ezetimibe; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Intestinal Absorption; Lipoproteins, LDL; Phytosterols; Pravastatin; Pyrroles; Simvastatin

2006
Cholesterol absorption inhibitors as a therapeutic option for hypercholesterolaemia.
    Expert opinion on investigational drugs, 2006, Volume: 15, Issue:11

    Topics: Acetyl-CoA C-Acyltransferase; Animals; Anticholesteremic Agents; Atherosclerosis; Azetidines; Bile Acids and Salts; Carrier Proteins; Cholesterol, Dietary; Drugs, Investigational; Ezetimibe; Humans; Hypercholesterolemia; Intestinal Absorption; Phytosterols

2006
[Change in the cholesterol metabolism associated with the combined inhibition of synthesis and absorption].
    Orvosi hetilap, 2007, Apr-08, Volume: 148, Issue:14

    Topics: Anticholesteremic Agents; Azetidines; Biomarkers; Cholestanol; Cholesterol; Cholesterol, Dietary; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Intestinal Absorption; Phytosterols; Sitosterols

2007
Lipid-lowering drugs acting at the level of the gastrointestinal tract.
    Current pharmaceutical design, 2009, Volume: 15, Issue:5

    Topics: Animals; Anti-Obesity Agents; Anticholesteremic Agents; Azetidines; Bile Acids and Salts; Clinical Trials as Topic; Ezetimibe; Gastrointestinal Tract; Humans; Lactones; Orlistat; Phytosterols

2009
Systematic review on evidence of the effectiveness of cholesterol-lowering drugs.
    Advances in therapy, 2010, Volume: 27, Issue:6

    Topics: Anticholesteremic Agents; Azetidines; Cholestyramine Resin; Coronary Disease; Drug Therapy, Combination; Evidence-Based Practice; Ezetimibe; Fatty Acids, Omega-3; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Niacin; Patient Selection; Phytosterols; Practice Guidelines as Topic; Primary Prevention; Risk Assessment; Risk Factors; Risk Reduction Behavior; Secondary Prevention; Treatment Outcome

2010
Current therapy for patients with sitosterolemia--effect of ezetimibe on plant sterol metabolism.
    Journal of atherosclerosis and thrombosis, 2010, Sep-30, Volume: 17, Issue:9

    Topics: Adolescent; Anticholesteremic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 5; ATP-Binding Cassette Transporters; Azetidines; Bile Acids and Salts; Cardiovascular Diseases; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Ileum; Ion Exchange Resins; Lipid Metabolism, Inborn Errors; Lipoproteins; Male; Models, Biological; Mutation, Missense; Phytosterols; Sitosterols; Young Adult

2010
Niemann-pick C1-like 1 (NPC1L1) protein in intestinal and hepatic cholesterol transport.
    Annual review of physiology, 2011, Volume: 73

    Topics: Animals; Anticholesteremic Agents; Atherosclerosis; Azetidines; Biliary Tract; Biological Transport; Carrier Proteins; Cholesterol; Endocytosis; Ezetimibe; Fatty Liver; Humans; Intestinal Absorption; Intestinal Mucosa; Intestines; Liver; Membrane Proteins; Membrane Transport Proteins; Mice; Obesity; Phytosterols; Primates

2011
Lowering LDL cholesterol with margarine containing plant stanol/sterol esters: is it still relevant in 2011?
    Complementary therapies in medicine, 2011, Volume: 19, Issue:1

    Topics: Anticholesteremic Agents; Azetidines; Cardiovascular Diseases; Cholesterol, HDL; Cholesterol, LDL; Diabetes Mellitus; Ezetimibe; Fibric Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hyperlipoproteinemia Type II; Intestinal Diseases; Lipid Metabolism, Inborn Errors; Margarine; Micronutrients; Niacin; Phytosterols; Sitosterols; Triglycerides

2011
Inhibition of cholesterol absorption: targeting the intestine.
    Pharmaceutical research, 2012, Volume: 29, Issue:12

    Topics: Animals; Anticholesteremic Agents; Apolipoproteins B; Atherosclerosis; Azetidines; Bile Acids and Salts; Cholesterol; Ezetimibe; Heart Diseases; Humans; Intestinal Absorption; Liver X Receptors; Molecular Targeted Therapy; Orphan Nuclear Receptors; Phytosterols; Sterol O-Acyltransferase; Transcription, Genetic

2012
Plant sterols and atherosclerosis.
    Current opinion in lipidology, 2013, Volume: 24, Issue:1

    Topics: Alleles; Animals; Anticholesteremic Agents; Atherosclerosis; ATP Binding Cassette Transporter, Subfamily G, Member 5; ATP Binding Cassette Transporter, Subfamily G, Member 8; ATP-Binding Cassette Transporters; Azetidines; Cholesterol, LDL; Ezetimibe; Genetic Loci; Humans; Lipoproteins; Phytosterols; Phytotherapy; Randomized Controlled Trials as Topic; Risk Factors; Sitosterols

2013
Non-cholesterol sterols and cholesterol metabolism in sitosterolemia.
    Atherosclerosis, 2013, Volume: 231, Issue:2

    Topics: Absorption; Atherosclerosis; ATP Binding Cassette Transporter, Subfamily G; ATP-Binding Cassette Transporters; Azetidines; Cholesterol; Disease Progression; Ezetimibe; Humans; Hypercholesterolemia; Intestinal Diseases; Kinetics; Lipid Metabolism, Inborn Errors; Membrane Proteins; Membrane Transport Proteins; Phytosterols; Sitosterols; Sterol O-Acyltransferase; Sterol O-Acyltransferase 2; Sterols; Xanthomatosis

2013
Toward individualized cholesterol-lowering treatment in end-stage renal disease.
    Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation, 2014, Volume: 24, Issue:2

    Topics: Azetidines; Cardiovascular Diseases; Cholesterol, Dietary; Cholesterol, LDL; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Intestinal Absorption; Kidney Failure, Chronic; Phytosterols; Polyamines; Randomized Controlled Trials as Topic; Renal Dialysis; Risk Factors; Sevelamer

2014
Sitosterolemia: diagnosis, investigation, and management.
    Current atherosclerosis reports, 2014, Volume: 16, Issue:7

    Topics: Anemia, Hemolytic; Animals; Anticholesteremic Agents; Atherosclerosis; Azetidines; Ezetimibe; Humans; Hypercholesterolemia; Intestinal Diseases; Lipid Metabolism, Inborn Errors; Mice; Phytosterols; Thrombocytopenia; Xanthomatosis

2014
Implementing phytosterols into medical practice as a cholesterol-lowering strategy: overview of efficacy, effectiveness, and safety.
    The Canadian journal of cardiology, 2014, Volume: 30, Issue:10

    Topics: Anticholesteremic Agents; Azetidines; Dietary Supplements; Dyslipidemias; Ezetimibe; Humans; Phytosterols; Treatment Outcome

2014
Non-cholesterol Sterols in the Diagnosis and Treatment of Dyslipidemias: A Review.
    Current medicinal chemistry, 2016, Volume: 23, Issue:20

    Topics: Bile Acids and Salts; Cholesterol; Dyslipidemias; Ezetimibe; Humans; Membrane Proteins; Membrane Transport Proteins; Oxysterols; Phytosterols; Pravastatin; Sterols

2016
Two novel variants of the ABCG5 gene cause xanthelasmas and macrothrombocytopenia: a brief review of hematologic abnormalities of sitosterolemia.
    Journal of thrombosis and haemostasis : JTH, 2017, Volume: 15, Issue:9

    Topics: Anticholesteremic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 5; DNA Mutational Analysis; Ezetimibe; Female; Genetic Predisposition to Disease; High-Throughput Nucleotide Sequencing; Humans; Hypercholesterolemia; Intestinal Diseases; Lipid Metabolism, Inborn Errors; Lipoproteins; Middle Aged; Mutation; Phenotype; Phytosterols; Sitosterols; Spain; Thrombocytopenia; Xanthomatosis

2017

Trials

14 trial(s) available for ezetimibe and phytosterols

ArticleYear
Ezetimibe effectively reduces plasma plant sterols in patients with sitosterolemia.
    Circulation, 2004, Mar-02, Volume: 109, Issue:8

    Topics: Adolescent; Adult; Aged; Anticholesteremic Agents; Apolipoproteins B; Arteriosclerosis; ATP Binding Cassette Transporter, Subfamily G, Member 5; ATP Binding Cassette Transporter, Subfamily G, Member 8; ATP-Binding Cassette Transporters; Azetidines; Child; Cholesterol; Cholesterol, Dietary; Double-Blind Method; Ezetimibe; Female; Genes, Recessive; Humans; Intestinal Absorption; Lipid Metabolism, Inborn Errors; Lipoproteins; Male; Middle Aged; Phytosterols; Sitosterols; Treatment Outcome

2004
Inhibition of cholesterol absorption by the combination of dietary plant sterols and ezetimibe: effects on plasma lipid levels.
    Journal of lipid research, 2005, Volume: 46, Issue:12

    Topics: Absorption; Azetidines; Cholesterol; Diet; Ezetimibe; Female; Humans; Lipids; Liver; Male; Middle Aged; Muscles; Phytosterols

2005
Disposition and sterol-lowering effect of ezetimibe are influenced by single-dose coadministration of rifampin, an inhibitor of multidrug transport proteins.
    Clinical pharmacology and therapeutics, 2006, Volume: 80, Issue:5

    Topics: Administration, Oral; Adult; Anticholesteremic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Sub-Family B Member 4; Azetidines; Cholesterol; Chromatography, Gas; Chromatography, Liquid; Cross-Over Studies; Enzyme Inhibitors; Ezetimibe; Feces; Female; Genotype; Glucuronides; Humans; Intestinal Absorption; Intestinal Mucosa; Intestines; Liver-Specific Organic Anion Transporter 1; Male; Multidrug Resistance-Associated Protein 2; Organic Anion Transporters; Phytosterols; Rifampin; Sitosterols; Time Factors

2006
Effects of ezetimibe, simvastatin, atorvastatin, and ezetimibe-statin therapies on non-cholesterol sterols in patients with primary hypercholesterolemia.
    Current medical research and opinion, 2008, Volume: 24, Issue:1

    Topics: Aged; Anticholesteremic Agents; Azetidines; Cholesterol; Double-Blind Method; Drug Therapy, Combination; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Phytosterols; Placebos; Simvastatin; Sitosterols; Sterols

2008
Baseline cholesterol absorption and the response to ezetimibe/simvastatin therapy: a post-hoc analysis of the ENHANCE trial.
    Journal of lipid research, 2010, Volume: 51, Issue:4

    Topics: Adult; Aged; Anticholesteremic Agents; Azetidines; Biomarkers; Cholesterol; Cholesterol, LDL; Double-Blind Method; Drug Therapy, Combination; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipoproteinemia Type II; Intestinal Absorption; Male; Middle Aged; Phytosterols; Simvastatin; Sitosterols; Statistics as Topic

2010
Lipid-lowering effects of ezetimibe for hypercholesterolemic patients with and without type 2 diabetes mellitus.
    Endocrine journal, 2010, Volume: 57, Issue:10

    Topics: Aged; Azetidines; Biomarkers; Body Mass Index; C-Reactive Protein; Cardiovascular Diseases; Cholestanol; Cholesterol; Cholesterol, LDL; Diabetes Mellitus, Type 2; Ezetimibe; Female; Humans; Hypercholesterolemia; Hypolipidemic Agents; Lipids; Male; Middle Aged; Phytosterols; Sitosterols

2010
Combined effects of ezetimibe and phytosterols on cholesterol metabolism: a randomized, controlled feeding study in humans.
    Circulation, 2011, Aug-02, Volume: 124, Issue:5

    Topics: Adult; Aged; Anticholesteremic Agents; Azetidines; Cholesterol, Dietary; Cholesterol, LDL; Combined Modality Therapy; Drug Synergism; Ezetimibe; Female; Humans; Hypercholesterolemia; Lipid Metabolism; Male; Middle Aged; Phytosterols; Young Adult

2011
The role of soluble fiber intake in patients under highly effective lipid-lowering therapy.
    Nutrition journal, 2011, Aug-02, Volume: 10

    Topics: Azetidines; Blood Glucose; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Dietary Fiber; Ezetimibe; Female; Fluorobenzenes; Humans; Hypercholesterolemia; Intestinal Diseases; Lipid Metabolism, Inborn Errors; Male; Middle Aged; Phytosterols; Pyrimidines; Rosuvastatin Calcium; Sitosterols; Sulfonamides; Triglycerides

2011
Effect of dalcetrapib, a CETP modulator, on non-cholesterol sterol markers of cholesterol homeostasis in healthy subjects.
    Atherosclerosis, 2011, Volume: 219, Issue:2

    Topics: Amides; Animals; Anticholesteremic Agents; Azetidines; Biomarkers; Cholestanol; Cholesterol; Cholesterol Ester Transfer Proteins; Cholesterol, HDL; Cricetinae; Cross-Over Studies; Desmosterol; Esters; Ezetimibe; Homeostasis; Humans; Intestinal Absorption; Lipid Metabolism; Male; Mesocricetus; Models, Animal; Phytosterols; Quinolines; Sitosterols; Sulfhydryl Compounds; Switzerland

2011
Long-term effects of ezetimibe-plus-statin therapy on low-density lipoprotein cholesterol levels as compared with double-dose statin therapy in patients with coronary artery disease.
    Atherosclerosis, 2012, Volume: 224, Issue:2

    Topics: Aged; Anticholesteremic Agents; Atorvastatin; Azetidines; Biomarkers; Cholesterol; Cholesterol, LDL; Coronary Artery Disease; Drug Administration Schedule; Drug Therapy, Combination; Ezetimibe; Female; Fluorobenzenes; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Japan; Male; Middle Aged; Phytosterols; Proprotein Convertase 9; Proprotein Convertases; Prospective Studies; Pyrimidines; Pyrroles; Rosuvastatin Calcium; Serine Endopeptidases; Sulfonamides; Time Factors; Treatment Outcome

2012
Effects of ezetimibe on markers of synthesis and absorption of cholesterol in high-risk patients with elevated C-reactive protein.
    Life sciences, 2013, May-02, Volume: 92, Issue:14-16

    Topics: Aged; Anticholesteremic Agents; Atorvastatin; Azetidines; C-Reactive Protein; Cardiovascular Diseases; Cholesterol; Desmosterol; Ezetimibe; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Male; Middle Aged; Phytosterols; Prospective Studies; Pyrroles; Risk Factors; Sitosterols; Statistics, Nonparametric

2013
Ezetimibe reduces plant sterol accumulation and favorably increases platelet count in sitosterolemia.
    The Journal of pediatrics, 2015, Volume: 166, Issue:1

    Topics: Adolescent; Adult; Anticholesteremic Agents; Azetidines; Canada; Cholesterol; Erythrocyte Count; Ezetimibe; Female; Humans; Hypercholesterolemia; Intestinal Diseases; Lipid Metabolism, Inborn Errors; Male; Middle Aged; Phytosterols; Pilot Projects; Platelet Count; Treatment Outcome; United States; Young Adult

2015
A Randomized Open-Label Trial to Assess the Effect of Plant Sterols Associated with Ezetimibe in Low-Density Lipoprotein Levels in Patients with Coronary Artery Disease on Statin Therapy.
    Journal of medicinal food, 2017, Volume: 20, Issue:1

    Topics: Adult; Aged; Anticholesteremic Agents; Coronary Artery Disease; Drug Therapy, Combination; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipoproteins, LDL; Male; Middle Aged; Phytosterols; Prospective Studies; Young Adult

2017
Thyroid Hormone Status in Sitosterolemia Is Modified by Ezetimibe.
    The Journal of pediatrics, 2017, Volume: 188

    Topics: Adolescent; Adult; Anticholesteremic Agents; Cholestanol; Cholestenones; Cholesterol; Ezetimibe; Female; Humans; Hypercholesterolemia; Intestinal Diseases; Lipid Metabolism, Inborn Errors; Male; Middle Aged; Phytosterols; Sitosterols; Thyrotropin; Thyroxine; Triiodothyronine; Young Adult

2017

Other Studies

28 other study(ies) available for ezetimibe and phytosterols

ArticleYear
[Ezetimibe (Ezetrol)].
    Revue medicale de Liege, 2004, Volume: 59, Issue:4

    Topics: Anticholesteremic Agents; Azetidines; Cardiovascular Diseases; Cholesterol; Drug Therapy, Combination; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Phytosterols; Treatment Outcome

2004
Effect of high plant sterol-enriched diet and cholesterol absorption inhibitor, SCH 58235, on plant sterol absorption and plasma concentrations in hypercholesterolemic wild-type Kyoto rats.
    Metabolism: clinical and experimental, 2005, Volume: 54, Issue:1

    Topics: Animals; Azetidines; Cholesterol; Diet; Ezetimibe; Hydroxymethylglutaryl CoA Reductases; Hypercholesterolemia; Intestinal Absorption; Male; Phytosterols; Rats; Rats, Inbred WKY; Rats, Wistar; Species Specificity

2005
Ezetimibe normalizes metabolic defects in mice lacking ABCG5 and ABCG8.
    Journal of lipid research, 2005, Volume: 46, Issue:8

    Topics: Absorption; Animals; ATP Binding Cassette Transporter, Subfamily G, Member 5; ATP Binding Cassette Transporter, Subfamily G, Member 8; ATP-Binding Cassette Transporters; Azetidines; Cholesterol; Ezetimibe; Lipoproteins; Liver; Mice; Mice, Knockout; Phytosterols; Sitosterols; Sterols

2005
Sequence variation in NPC1L1 and association with improved LDL-cholesterol lowering in response to ezetimibe treatment.
    Genomics, 2005, Volume: 86, Issue:6

    Topics: Anticholesteremic Agents; Azetidines; Black or African American; Cholesterol, LDL; Ezetimibe; Gene Frequency; Genetic Variation; Hispanic or Latino; Humans; Intestinal Absorption; Membrane Proteins; Membrane Transport Proteins; Phytosterols; Polymorphism, Single Nucleotide; Sequence Analysis, DNA; United States; White People

2005
Serum plant sterols and atherosclerosis: is there a place for statin-ezetimibe combination?
    Journal of the American College of Cardiology, 2006, Apr-04, Volume: 47, Issue:7

    Topics: Anticholesteremic Agents; Azetidines; Coronary Artery Disease; Drug Therapy, Combination; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Phytosterols; Risk Factors

2006
Lower cholesterol without statins. Options are available.
    Mayo Clinic health letter (English ed.), 2006, Volume: 24, Issue:5

    Topics: Allylamine; Azetidines; Cholesterol, LDL; Cholinergic Antagonists; Colesevelam Hydrochloride; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Niacin; Phytosterols

2006
Disposition and sterol-lowering effect of ezetimibe in multidrug resistance-associated protein 2-deficient rats.
    The Journal of pharmacology and experimental therapeutics, 2006, Volume: 318, Issue:3

    Topics: Animals; Anticholesteremic Agents; Azetidines; Cholesterol; Ezetimibe; Glucuronosyltransferase; Male; Membrane Transport Proteins; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Phytosterols; Rats; Rats, Inbred Lew; RNA, Messenger

2006
Efficacy and safety of ezetimibe in patients undergoing hemodialysis.
    Endocrine journal, 2010, Volume: 57, Issue:11

    Topics: Aged; Anticholesteremic Agents; Azetidines; C-Reactive Protein; Cholesterol; Dyslipidemias; Ezetimibe; Female; Glycated Hemoglobin; Humans; Linear Models; Male; Middle Aged; Phytosterols; Renal Dialysis; Renal Insufficiency; Triglycerides

2010
Do functional foods have a role in the prevention of cardiovascular disease?
    Circulation, 2011, Aug-02, Volume: 124, Issue:5

    Topics: Anticholesteremic Agents; Azetidines; Blood Pressure; Cholesterol, Dietary; Dietary Proteins; Ezetimibe; Female; Humans; Hypercholesterolemia; Hypertension; Lipid Metabolism; Male; Milk Proteins; Phytosterols; Soybean Proteins

2011
Dietary xenosterols lead to infertility and loss of abdominal adipose tissue in sterolin-deficient mice.
    Journal of lipid research, 2013, Volume: 54, Issue:2

    Topics: Abdominal Fat; Adipocytes; Adipose Tissue, White; Animals; ATP Binding Cassette Transporter, Subfamily G, Member 5; ATP Binding Cassette Transporter, Subfamily G, Member 8; ATP-Binding Cassette Transporters; Azetidines; Cell Size; Dietary Fats; Ezetimibe; Fatty Acids; Female; Gene Expression Regulation; Gene Knockout Techniques; Glucose Tolerance Test; Humans; Infertility, Female; Infertility, Male; Intestinal Mucosa; Intestines; Lipoproteins; Male; Mice; Phytosterols; Testis

2013
Ezetimibe decreases serum oxidized cholesterol without impairing bile acid synthesis in Japanese hypercholesterolemic patients.
    Atherosclerosis, 2013, Volume: 230, Issue:1

    Topics: Absorption; Aged; Anthropometry; Anticholesteremic Agents; Azetidines; Bile Acids and Salts; Body Mass Index; Case-Control Studies; Cholesterol; Diet; Ezetimibe; Female; Gas Chromatography-Mass Spectrometry; Humans; Hydroxycholesterols; Hypercholesterolemia; Intestine, Small; Japan; Life Style; Male; Middle Aged; Oxygen; Phytosterols; Sterols; Triglycerides

2013
Phytosterols protect against diet-induced hypertriglyceridemia in Syrian golden hamsters.
    Lipids in health and disease, 2014, Jan-06, Volume: 13

    Topics: Animals; Anticholesteremic Agents; Azetidines; Cholesterol, HDL; Cricetinae; Diet, High-Fat; Drug Evaluation, Preclinical; Ezetimibe; Fatty Acids; Gene Expression; Hypertriglyceridemia; Intestinal Absorption; Intestine, Small; Lipogenesis; Liver; Male; Mesocricetus; Phytosterols; RNA, Messenger; Sterol Regulatory Element Binding Protein 1

2014
A novel mutation of ABCG5 gene in a Turkish boy with phytosterolemia presenting with macrotrombocytopenia and stomatocytosis.
    Pediatric blood & cancer, 2014, Volume: 61, Issue:8

    Topics: Anticholesteremic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 5; ATP Binding Cassette Transporter, Subfamily G, Member 8; ATP-Binding Cassette Transporters; Azetidines; Child; Ezetimibe; Hematologic Diseases; Humans; Hypercholesterolemia; Intestinal Diseases; Lipid Metabolism, Inborn Errors; Lipoproteins; Male; Phytosterols; Point Mutation

2014
20-year-old amish woman with abdominal pain, retroperitoneal mass, and hyperlipidemia.
    Arthritis care & research, 2015, Volume: 67, Issue:3

    Topics: Abdominal Pain; Amish; Anticholesteremic Agents; Azetidines; Biopsy; Diagnosis, Differential; Ezetimibe; Female; Humans; Hypercholesterolemia; Intestinal Diseases; Lipid Metabolism, Inborn Errors; Phytosterols; Predictive Value of Tests; Retroperitoneal Fibrosis; Retroperitoneal Space; Tomography, X-Ray Computed; Treatment Outcome; Xanthomatosis; Young Adult

2015
Effects of ezetimibe on cholesterol metabolism in HIV-infected patients with protease inhibitor-associated dyslipidemia: a single-arm intervention trial.
    BMC infectious diseases, 2014, Sep-11, Volume: 14

    Topics: Adult; Aged; Anticholesteremic Agents; Azetidines; C-Reactive Protein; Cholesterol; Cholesterol, LDL; Dyslipidemias; Ezetimibe; Female; HIV Infections; Humans; Lipid Metabolism; Male; Middle Aged; Phytosterols; Protease Inhibitors

2014
Long-term administration of a Niemann-Pick C1-like 1 inhibitor, ezetimibe, does not worsen bile lithogenicity in dyslipidemic patients with hepatobiliary diseases.
    Journal of hepato-biliary-pancreatic sciences, 2016, Volume: 23, Issue:2

    Topics: Anticholesteremic Agents; Bile; Cholesterol; Dyslipidemias; Ezetimibe; Fatty Liver; Female; Gallstones; Humans; Lipid Metabolism; Lipoproteins; Male; Middle Aged; Phytosterols; Ursodeoxycholic Acid

2016
[Association between very low density lipoprotein cholesterol and cholesterol absorption/synthesis markers in patients with moderate and high risk of coronary heart disease].
    Zhonghua xin xue guan bing za zhi, 2015, Volume: 43, Issue:11

    Topics: Atorvastatin; Biomarkers; Cholesterol; Cholesterol, LDL; Cholesterol, VLDL; Coronary Artery Disease; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Phytosterols; Risk Factors

2015
Ezetimibe Promotes Brush Border Membrane-to-Lumen Cholesterol Efflux in the Small Intestine.
    PloS one, 2016, Volume: 11, Issue:3

    Topics: Animals; Biological Transport; Caco-2 Cells; Cell Differentiation; Cholesterol; Enterocytes; Ezetimibe; Hep G2 Cells; Humans; Intestinal Absorption; Intestine, Small; Male; Membrane Transport Proteins; Membranes; Mice, Inbred C57BL; Mice, Knockout; Microvilli; Mucus; Perfusion; Phytosterols; Tritium

2016
Effect of ezetimibe on low- and high-density lipoprotein subclasses in sitosterolemia.
    Atherosclerosis, 2017, Volume: 260

    Topics: Adolescent; Adult; Anticholesteremic Agents; Cholesterol, HDL; Electrophoresis, Polyacrylamide Gel; Ezetimibe; Female; Humans; Hypercholesterolemia; Intestinal Diseases; Lipid Metabolism, Inborn Errors; Lipoproteins, HDL; Lipoproteins, IDL; Lipoproteins, VLDL; Male; Middle Aged; Phytosterols; Treatment Outcome; Young Adult

2017
Antiatherogenic potential of ezetimibe in sitosterolemia: Beyond plant sterols lowering.
    Atherosclerosis, 2017, Volume: 260

    Topics: Ezetimibe; Humans; Hypercholesterolemia; Intestinal Diseases; Lipid Metabolism, Inborn Errors; Lipoproteins, HDL; Phytosterols

2017
Timely diagnosis of sitosterolemia by next generation sequencing in two children with severe hypercholesterolemia.
    Atherosclerosis, 2017, Volume: 262

    Topics: Anticholesteremic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 5; ATP Binding Cassette Transporter, Subfamily G, Member 8; Biomarkers; Child; Child, Preschool; Cholesterol, LDL; Codon, Nonsense; Diet, Fat-Restricted; DNA Mutational Analysis; Ezetimibe; Female; Genetic Predisposition to Disease; Heterozygote; High-Throughput Nucleotide Sequencing; Humans; Hypercholesterolemia; Intestinal Diseases; Lipid Metabolism, Inborn Errors; Lipoproteins; Male; Phenotype; Phytosterols; Predictive Value of Tests; Severity of Illness Index; Treatment Outcome; Up-Regulation

2017
Carotid intima media thickness in a girl with sitosterolemia carrying a homozygous mutation in the ABCG5 gene.
    Journal of pediatric endocrinology & metabolism : JPEM, 2017, Aug-28, Volume: 30, Issue:9

    Topics: Anticholesteremic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 5; Carotid Arteries; Carotid Intima-Media Thickness; Child, Preschool; Cholesterol, LDL; Echocardiography; Ezetimibe; Female; Humans; Hypercholesterolemia; Intestinal Diseases; Lipid Metabolism, Inborn Errors; Lipoproteins; Mutation; Phytosterols

2017
The natural history of phytosterolemia: Observations on its homeostasis.
    Atherosclerosis, 2018, Volume: 269

    Topics: Adolescent; Adult; Age Factors; Anticholesteremic Agents; Asymptomatic Diseases; ATP Binding Cassette Transporter, Subfamily G, Member 8; Biomarkers; Canada; Child; Child, Preschool; Cholesterol; Ezetimibe; Female; Genetic Predisposition to Disease; Homeostasis; Humans; Hypercholesterolemia; Infant; Intestinal Diseases; Lipid Metabolism, Inborn Errors; Male; Middle Aged; Mutation; Phenotype; Phytosterols; Prevalence; Puberty; Rare Diseases; Risk Factors; Sitosterols; Time Factors; Treatment Outcome; United States; Young Adult

2018
A case of ezetimibe-effective hypercholesterolemia with a novel heterozygous variant in ABCG5.
    Endocrine journal, 2020, Nov-28, Volume: 67, Issue:11

    Topics: Anticholesteremic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 5; Cholesterol; Cholesterol, LDL; Diagnostic Errors; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hyperlipoproteinemia Type II; Intestinal Diseases; Lipid Metabolism, Inborn Errors; Lipoproteins; Loss of Function Mutation; Middle Aged; Phytosterols; Sitosterols; Treatment Failure

2020
Sitosterolemia Exhibiting Severe Hypercholesterolemia with Tendon Xanthomas Due to Compound Heterozygous ABCG5 Gene Mutations Treated with Ezetimibe and Alirocumab.
    Internal medicine (Tokyo, Japan), 2020, Dec-01, Volume: 59, Issue:23

    Topics: Achilles Tendon; Antibodies, Monoclonal, Humanized; Anticholesteremic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 5; Cholesterol, LDL; Ezetimibe; Humans; Hypercholesterolemia; Intestinal Diseases; Lipid Metabolism, Inborn Errors; Male; Middle Aged; Mutation; Phytosterols; Treatment Outcome; Xanthomatosis

2020
Plant sterol hyperabsorption caused by uncontrolled diabetes in a patient with a heterozygous ABCG5 variant.
    Journal of diabetes investigation, 2022, Volume: 13, Issue:11

    Topics: ATP Binding Cassette Transporter, Subfamily G, Member 5; Diabetes Mellitus; Ezetimibe; Humans; Hypercholesterolemia; Intestinal Diseases; Lipid Metabolism, Inborn Errors; Lipoproteins; Phytosterols

2022
Increased cholesterol absorption is associated with In-stent-restenosis after stent implantation for stable coronary artery disease.
    Steroids, 2022, Volume: 187

    Topics: Cholesterol, LDL; Constriction, Pathologic; Coronary Angiography; Coronary Artery Disease; Coronary Restenosis; Ezetimibe; Female; Gas Chromatography-Mass Spectrometry; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Phytosterols; Stents; Triglycerides

2022
Relationship between Diabetes Mellitus and Serum Lathosterol and Campesterol Levels: The CACHE Study DM Analysis.
    Journal of atherosclerosis and thrombosis, 2023, Jul-01, Volume: 30, Issue:7

    Topics: Biomarkers; Cholesterol; Diabetes Mellitus; Ezetimibe; Female; Glycated Hemoglobin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Middle Aged; Phytosterols

2023