ezetimibe has been researched along with nortriptyline in 4 studies
| Studies (ezetimibe) | Trials (ezetimibe) | Recent Studies (post-2010) (ezetimibe) | Studies (nortriptyline) | Trials (nortriptyline) | Recent Studies (post-2010) (nortriptyline) |
|---|---|---|---|---|---|
| 2,484 | 563 | 1,465 | 2,289 | 517 | 327 |
| Protein | Taxonomy | ezetimibe (IC50) | nortriptyline (IC50) |
|---|---|---|---|
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | 0.016 | |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | 0.0032 | |
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | 0.347 | |
| Muscarinic acetylcholine receptor M4 | Homo sapiens (human) | 0.095 | |
| 5-hydroxytryptamine receptor 2C | Rattus norvegicus (Norway rat) | 0.17 | |
| Muscarinic acetylcholine receptor M5 | Homo sapiens (human) | 0.027 | |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | 0.366 | |
| Cytochrome P450 2D26 | Rattus norvegicus (Norway rat) | 1.9 | |
| Cytochrome P450 2D6 | Homo sapiens (human) | 1.95 | |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | 0.082 | |
| 5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | 0.17 | |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | 0.047 | |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | 0.1015 | |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 1.019 | |
| Muscarinic acetylcholine receptor M3 | Homo sapiens (human) | 0.171 | |
| D(1A) dopamine receptor | Homo sapiens (human) | 0.539 | |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | 0.0032 | |
| Histamine H2 receptor | Homo sapiens (human) | 2.334 | |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | 0.273 | |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | 0.051 | |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | 0.016 | |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | 1.019 | |
| 5-hydroxytryptamine receptor 1D | Rattus norvegicus (Norway rat) | 0.17 | |
| 5-hydroxytryptamine receptor 1F | Rattus norvegicus (Norway rat) | 0.17 | |
| 5-hydroxytryptamine receptor 2B | Rattus norvegicus (Norway rat) | 0.17 | |
| 5-hydroxytryptamine receptor 6 | Rattus norvegicus (Norway rat) | 0.17 | |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | 0.013 | |
| 5-hydroxytryptamine receptor 7 | Rattus norvegicus (Norway rat) | 0.17 | |
| Cytochrome P450 2C19 | Homo sapiens (human) | 3 | |
| 5-hydroxytryptamine receptor 5A | Rattus norvegicus (Norway rat) | 0.17 | |
| 5-hydroxytryptamine receptor 5B | Rattus norvegicus (Norway rat) | 0.17 | |
| Histamine H1 receptor | Homo sapiens (human) | 0.05 | |
| D(3) dopamine receptor | Homo sapiens (human) | 0.179 | |
| 5-hydroxytryptamine receptor 3A | Rattus norvegicus (Norway rat) | 0.17 | |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 0.136 | |
| Histamine H2 receptor | Cavia porcellus (domestic guinea pig) | 7 | |
| 5-hydroxytryptamine receptor 6 | Homo sapiens (human) | 0.554 | |
| Voltage-dependent N-type calcium channel subunit alpha-1B | Homo sapiens (human) | 10 | |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | 1.678 | |
| 5-hydroxytryptamine receptor 4 | Rattus norvegicus (Norway rat) | 0.17 | |
| 5-hydroxytryptamine receptor 3B | Rattus norvegicus (Norway rat) | 0.17 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chang, TK; Ensom, MH; Kiang, TK | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
2 review(s) available for ezetimibe and nortriptyline
| Article | Year |
|---|---|
UDP-glucuronosyltransferases and clinical drug-drug interactions.
Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic | 2005 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
2 other study(ies) available for ezetimibe and nortriptyline
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |