ezetimibe and losartan
ezetimibe has been researched along with losartan in 5 studies
Compound Research Comparison
Studies (ezetimibe) | Trials (ezetimibe) | Recent Studies (post-2010) (ezetimibe) | Studies (losartan) | Trials (losartan) | Recent Studies (post-2010) (losartan) |
---|---|---|---|---|---|
2,484 | 563 | 1,465 | 7,231 | 1,245 | 2,118 |
Protein Interaction Comparison
Protein | Taxonomy | ezetimibe (IC50) | losartan (IC50) |
---|---|---|---|
Bile salt export pump | Homo sapiens (human) | 9.01 | |
Cytochrome P450 2C9 | Homo sapiens (human) | 2.882 | |
Angiotensin-converting enzyme | Homo sapiens (human) | 0.019 | |
Atrial natriuretic peptide receptor 3 | Homo sapiens (human) | 0.0018 | |
5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 0.019 | |
Type-1A angiotensin II receptor | Rattus norvegicus (Norway rat) | 0.0247 | |
Type-1B angiotensin II receptor | Rattus norvegicus (Norway rat) | 0.0234 | |
Adenosine receptor A2a | Rattus norvegicus (Norway rat) | 0.0032 | |
Type-1 angiotensin II receptor | Homo sapiens (human) | 0.047 | |
Type-1 angiotensin II receptor | Oryctolagus cuniculus (rabbit) | 0.025 | |
Type-2 angiotensin II receptor | Rattus norvegicus (Norway rat) | 0.0118 | |
Type-2 angiotensin II receptor | Homo sapiens (human) | 0.019 | |
Platelet glycoprotein VI | Homo sapiens (human) | 4 | |
Solute carrier organic anion transporter family member 1B3 | Homo sapiens (human) | 1.1481 | |
Type-1 angiotensin II receptor | Cavia porcellus (domestic guinea pig) | 0.018 | |
Solute carrier organic anion transporter family member 1B1 | Homo sapiens (human) | 0.2884 |
Research
Studies (5)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (20.00) | 29.6817 |
2010's | 3 (60.00) | 24.3611 |
2020's | 1 (20.00) | 2.80 |
Authors
Authors | Studies |
---|---|
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
Meanwell, NA | 1 |
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
Ambrosi, P; Andréjak, M; Gayet, JL | 1 |
Ahn, Y; Chae, IH; Hong, SJ; Hong, TJ; Kang, DH; Kim, BK; Kim, H; Kim, HS; Kim, MC; Kim, MH; Kim, SH; Kim, SY; Kim, W; Rhee, MY | 1 |
Reviews
2 review(s) available for ezetimibe and losartan
Article | Year |
---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
[The best of clinical pharmacology in 2002].
Topics: Anticholesteremic Agents; Antihypertensive Agents; Azetidines; Cardiovascular Diseases; Ezetimibe; Hormone Replacement Therapy; Humans; Hydrazones; Hypercholesterolemia; Losartan; Myocardial Infarction; Natriuretic Agents; Natriuretic Peptide, Brain; Neovascularization, Physiologic; Nicorandil; Pyridazines; Randomized Controlled Trials as Topic; Simendan; Vasodilator Agents | 2003 |
Trials
1 trial(s) available for ezetimibe and losartan
Article | Year |
---|---|
A Randomized, Multicenter, Double-blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of a Quadruple Combination of Amlodipine, Losartan, Rosuvastatin, and Ezetimibe in Patients with Concomitant Essential Hypertension and Dyslipidemia.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Cholesterol, LDL; Double-Blind Method; Dyslipidemias; Essential Hypertension; Ezetimibe; Humans; Hypertension; Losartan; Rosuvastatin Calcium; Treatment Outcome | 2023 |
Other Studies
2 other study(ies) available for ezetimibe and losartan
Article | Year |
---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Synopsis of some recent tactical application of bioisosteres in drug design.
Topics: Cytochrome P-450 Enzyme System; Drug Design | 2011 |