Page last updated: 2024-09-04

ezetimibe and gamma-sitosterol

ezetimibe has been researched along with gamma-sitosterol in 24 studies

Compound Research Comparison

Studies
(ezetimibe)
Trials
(ezetimibe)
Recent Studies (post-2010)
(ezetimibe)
Studies
(gamma-sitosterol)
Trials
(gamma-sitosterol)
Recent Studies (post-2010) (gamma-sitosterol)
2,4845631,4651,70494669

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's11 (45.83)29.6817
2010's12 (50.00)24.3611
2020's1 (4.17)2.80

Authors

AuthorsStudies
Frölich, JC; Pham, VV1
Cohen, JC; Hobbs, HH; Lütjohann, D; von Bergmann, K; Yu, L1
Patel, SB; Salen, G; Sisk, CM; Starc, T1
Giessmann, T; Luetjohann, D; Oswald, S; Rosskopf, D; Siegmund, W; Wegner, D; Weitschies, W1
Suzuki, H; Takada, T; Yamanashi, Y1
Conejo-Mir, JS; Fernandez-Freire, LR; Guirado, SS; Muñoz, MA; Ortíz, JV; Wite, JB1
Márk, L; Paragh, G1
Assmann, G; Gutkin, SW; Kannenberg, F; Musliner, TA; Ramey, DR; Veltri, EP1
Beers, L; Bleasby, K; Braun, M; Garcia, ML; Hafey, M; Kaczorowski, GJ; Köhler, MG; Leone, J; Liu, J; McCann, ME; Nketiah, EO; Schmalhofer, W; Smith, L; Tang, YS; Thomas, A; Ujjainwalla, F; Weinglass, AB; Williams, B1
Cselovszky, D; Lütjohann, D; McCrary Sisk, C; Musliner, T; Salen, G; Sapre, A; Sirah, W; von Bergmann, K1
Johnson-Levonas, AO; Lin, J; Lütjohann, D; Macdonell, G; Musliner, T; Sapre, A; Shah, A; Sirah, W; von Bergmann, K1
Groen, AK; Hutten, BA; Jakulj, L; Kastelein, JJ; Lutjohann, D; Veltri, EP; Vissers, MN1
Masuda, D; Nakagawa-Toyama, Y; Nishida, M; Ohama, T; Tsubakio-Yamamoto, K; Yamashita, S1
Ishibashi, S; Kotani, K; Miyamoto, M; Nagasaka, S; Okada, K; Osuga, J; Yagyu, H1
Borges, NC; Fonseca, FA; Helfenstein, T; Izar, MC; Kasmas, SH; Moreira, FT; Moreno, RA; Ramos, SC; Rezende, VM; Silva, FC1
Blum, D; Chaput, E; Derks, M; Kallend, D; Niesor, EJ; Staempfli, A1
Lin, J; Lowe, RS; Schaefer, EJ; Shah, AK; Tershakovec, AM; Thongtang, N; Tomassini, JE1
Genser, B; März, W; Nestel, P; Silbernagel, G1
Aguirre, AC; Amaral, JB; Barbosa, SP; Bianco, HT; Fonseca, FA; França, CN; Izar, MC; Lins, LC; Matos, LN; Santana, JM1
Ballantyne, CM; Cain, VA; Hoogeveen, RC; Karlson, BW; Palmer, MK; Raya, JL1
Bastida, JM; Benito, R; Díez-Campelo, M; Girós, M; González-Porras, JR; Hernández-Rivas, JM; Hernández-Sánchez, JM; Hortal, A; Janusz, K; Lozano, ML; Marcellini, S; Rivera, J1
Dembinski, T; Hatch, GM; Mymin, D; Salen, G; Triggs-Raine, B; Waggoner, DJ1
Arashi, H; Endo, Y; Hagiwara, N; Kawada-Watanabe, E; Koyanagi, R; Matsui, K; Nakao, K; Ogawa, H; Oka, T; Saito, K; Sekiguchi, H; Tanaka, H; Tobaru, T; Uchida, T; Yamaguchi, J1
Dateki, S; Ikeda, K; Kashimada, K; Komiya, C; Mishima, H; Nakano, Y; Ogawa, Y; Shiba, K; Shimizu, H; Tsujimoto, K; Yamada, T; Yoshiura, KI1

Reviews

4 review(s) available for ezetimibe and gamma-sitosterol

ArticleYear
[Change in the cholesterol metabolism associated with the combined inhibition of synthesis and absorption].
    Orvosi hetilap, 2007, Apr-08, Volume: 148, Issue:14

    Topics: Anticholesteremic Agents; Azetidines; Biomarkers; Cholestanol; Cholesterol; Cholesterol, Dietary; Ezetimibe; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Intestinal Absorption; Phytosterols; Sitosterols

2007
Current therapy for patients with sitosterolemia--effect of ezetimibe on plant sterol metabolism.
    Journal of atherosclerosis and thrombosis, 2010, Sep-30, Volume: 17, Issue:9

    Topics: Adolescent; Anticholesteremic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 5; ATP-Binding Cassette Transporters; Azetidines; Bile Acids and Salts; Cardiovascular Diseases; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Ileum; Ion Exchange Resins; Lipid Metabolism, Inborn Errors; Lipoproteins; Male; Models, Biological; Mutation, Missense; Phytosterols; Sitosterols; Young Adult

2010
Plant sterols and atherosclerosis.
    Current opinion in lipidology, 2013, Volume: 24, Issue:1

    Topics: Alleles; Animals; Anticholesteremic Agents; Atherosclerosis; ATP Binding Cassette Transporter, Subfamily G, Member 5; ATP Binding Cassette Transporter, Subfamily G, Member 8; ATP-Binding Cassette Transporters; Azetidines; Cholesterol, LDL; Ezetimibe; Genetic Loci; Humans; Lipoproteins; Phytosterols; Phytotherapy; Randomized Controlled Trials as Topic; Risk Factors; Sitosterols

2013
Two novel variants of the ABCG5 gene cause xanthelasmas and macrothrombocytopenia: a brief review of hematologic abnormalities of sitosterolemia.
    Journal of thrombosis and haemostasis : JTH, 2017, Volume: 15, Issue:9

    Topics: Anticholesteremic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 5; DNA Mutational Analysis; Ezetimibe; Female; Genetic Predisposition to Disease; High-Throughput Nucleotide Sequencing; Humans; Hypercholesterolemia; Intestinal Diseases; Lipid Metabolism, Inborn Errors; Lipoproteins; Middle Aged; Mutation; Phenotype; Phytosterols; Sitosterols; Spain; Thrombocytopenia; Xanthomatosis

2017

Trials

11 trial(s) available for ezetimibe and gamma-sitosterol

ArticleYear
Disposition and sterol-lowering effect of ezetimibe are influenced by single-dose coadministration of rifampin, an inhibitor of multidrug transport proteins.
    Clinical pharmacology and therapeutics, 2006, Volume: 80, Issue:5

    Topics: Administration, Oral; Adult; Anticholesteremic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Sub-Family B Member 4; Azetidines; Cholesterol; Chromatography, Gas; Chromatography, Liquid; Cross-Over Studies; Enzyme Inhibitors; Ezetimibe; Feces; Female; Genotype; Glucuronides; Humans; Intestinal Absorption; Intestinal Mucosa; Intestines; Liver-Specific Organic Anion Transporter 1; Male; Multidrug Resistance-Associated Protein 2; Organic Anion Transporters; Phytosterols; Rifampin; Sitosterols; Time Factors

2006
Effects of ezetimibe, simvastatin, atorvastatin, and ezetimibe-statin therapies on non-cholesterol sterols in patients with primary hypercholesterolemia.
    Current medical research and opinion, 2008, Volume: 24, Issue:1

    Topics: Aged; Anticholesteremic Agents; Azetidines; Cholesterol; Double-Blind Method; Drug Therapy, Combination; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Phytosterols; Placebos; Simvastatin; Sitosterols; Sterols

2008
Efficacy and safety of ezetimibe 40 mg vs. ezetimibe 10 mg in the treatment of patients with homozygous sitosterolaemia.
    International journal of clinical practice, 2008, Volume: 62, Issue:7

    Topics: Adolescent; Adult; Aged; Anticholesteremic Agents; Azetidines; Dose-Response Relationship, Drug; Double-Blind Method; Ezetimibe; Female; Humans; Lipid Metabolism, Inborn Errors; Male; Middle Aged; Sitosterols; Treatment Outcome; Young Adult

2008
Long-term efficacy and safety of ezetimibe 10 mg in patients with homozygous sitosterolemia: a 2-year, open-label extension study.
    International journal of clinical practice, 2008, Volume: 62, Issue:10

    Topics: Achilles Tendon; Adolescent; Adult; Aged; Anticholesteremic Agents; Azetidines; Child; Double-Blind Method; Ezetimibe; Female; Homozygote; Humans; Hypercholesterolemia; Male; Middle Aged; Sitosterols; Treatment Outcome; Young Adult

2008
Baseline cholesterol absorption and the response to ezetimibe/simvastatin therapy: a post-hoc analysis of the ENHANCE trial.
    Journal of lipid research, 2010, Volume: 51, Issue:4

    Topics: Adult; Aged; Anticholesteremic Agents; Azetidines; Biomarkers; Cholesterol; Cholesterol, LDL; Double-Blind Method; Drug Therapy, Combination; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipoproteinemia Type II; Intestinal Absorption; Male; Middle Aged; Phytosterols; Simvastatin; Sitosterols; Statistics as Topic

2010
Lipid-lowering effects of ezetimibe for hypercholesterolemic patients with and without type 2 diabetes mellitus.
    Endocrine journal, 2010, Volume: 57, Issue:10

    Topics: Aged; Azetidines; Biomarkers; Body Mass Index; C-Reactive Protein; Cardiovascular Diseases; Cholestanol; Cholesterol; Cholesterol, LDL; Diabetes Mellitus, Type 2; Ezetimibe; Female; Humans; Hypercholesterolemia; Hypolipidemic Agents; Lipids; Male; Middle Aged; Phytosterols; Sitosterols

2010
The role of soluble fiber intake in patients under highly effective lipid-lowering therapy.
    Nutrition journal, 2011, Aug-02, Volume: 10

    Topics: Azetidines; Blood Glucose; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Dietary Fiber; Ezetimibe; Female; Fluorobenzenes; Humans; Hypercholesterolemia; Intestinal Diseases; Lipid Metabolism, Inborn Errors; Male; Middle Aged; Phytosterols; Pyrimidines; Rosuvastatin Calcium; Sitosterols; Sulfonamides; Triglycerides

2011
Effect of dalcetrapib, a CETP modulator, on non-cholesterol sterol markers of cholesterol homeostasis in healthy subjects.
    Atherosclerosis, 2011, Volume: 219, Issue:2

    Topics: Amides; Animals; Anticholesteremic Agents; Azetidines; Biomarkers; Cholestanol; Cholesterol; Cholesterol Ester Transfer Proteins; Cholesterol, HDL; Cricetinae; Cross-Over Studies; Desmosterol; Esters; Ezetimibe; Homeostasis; Humans; Intestinal Absorption; Lipid Metabolism; Male; Mesocricetus; Models, Animal; Phytosterols; Quinolines; Sitosterols; Sulfhydryl Compounds; Switzerland

2011
Effects of ezetimibe added to statin therapy on markers of cholesterol absorption and synthesis and LDL-C lowering in hyperlipidemic patients.
    Atherosclerosis, 2012, Volume: 225, Issue:2

    Topics: Aged; Anticholesteremic Agents; Apolipoproteins; Azetidines; Biomarkers; C-Reactive Protein; Cholesterol; Cholesterol, LDL; Double-Blind Method; Drug Therapy, Combination; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Intestinal Absorption; Male; Middle Aged; Multivariate Analysis; Sitosterols; Time Factors; Treatment Outcome; United States

2012
Effects of ezetimibe on markers of synthesis and absorption of cholesterol in high-risk patients with elevated C-reactive protein.
    Life sciences, 2013, May-02, Volume: 92, Issue:14-16

    Topics: Aged; Anticholesteremic Agents; Atorvastatin; Azetidines; C-Reactive Protein; Cardiovascular Diseases; Cholesterol; Desmosterol; Ezetimibe; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Male; Middle Aged; Phytosterols; Prospective Studies; Pyrroles; Risk Factors; Sitosterols; Statistics, Nonparametric

2013
Efficacy, safety and effect on biomarkers related to cholesterol and lipoprotein metabolism of rosuvastatin 10 or 20 mg plus ezetimibe 10 mg vs. simvastatin 40 or 80 mg plus ezetimibe 10 mg in high-risk patients: Results of the GRAVITY randomized study.
    Atherosclerosis, 2014, Volume: 232, Issue:1

    Topics: Absorption; Adult; Atherosclerosis; Azetidines; Biomarkers; Cholesterol, LDL; Coronary Disease; Drug Administration Schedule; Ezetimibe; Female; Fluorobenzenes; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipids; Lipoproteins; Male; Pyrimidines; Risk; Rosuvastatin Calcium; Simvastatin; Sitosterols; Sulfonamides; Treatment Outcome

2014

Other Studies

9 other study(ies) available for ezetimibe and gamma-sitosterol

ArticleYear
[Can ezetimib also be used as a treatment for beta-sitosterol].
    Deutsche medizinische Wochenschrift (1946), 2004, Jun-11, Volume: 129, Issue:24

    Topics: Anticholesteremic Agents; Azetidines; Ezetimibe; Humans; Sitosterols

2004
Ezetimibe normalizes metabolic defects in mice lacking ABCG5 and ABCG8.
    Journal of lipid research, 2005, Volume: 46, Issue:8

    Topics: Absorption; Animals; ATP Binding Cassette Transporter, Subfamily G, Member 5; ATP Binding Cassette Transporter, Subfamily G, Member 8; ATP-Binding Cassette Transporters; Azetidines; Cholesterol; Ezetimibe; Lipoproteins; Liver; Mice; Mice, Knockout; Phytosterols; Sitosterols; Sterols

2005
Intestinal cholesterol absorption inhibitor ezetimibe added to cholestyramine for sitosterolemia and xanthomatosis.
    Gastroenterology, 2006, Volume: 130, Issue:6

    Topics: Anticholesteremic Agents; Azetidines; Child; Cholestyramine Resin; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Ezetimibe; Female; Follow-Up Studies; Humans; Risk Assessment; Severity of Illness Index; Sitosterols; Treatment Outcome; Xanthomatosis

2006
Niemann-Pick C1-like 1 overexpression facilitates ezetimibe-sensitive cholesterol and beta-sitosterol uptake in CaCo-2 cells.
    The Journal of pharmacology and experimental therapeutics, 2007, Volume: 320, Issue:2

    Topics: Anticholesteremic Agents; Azetidines; Caco-2 Cells; Cholesterol; Ezetimibe; Humans; Membrane Transport Proteins; Micelles; Phosphatidylcholines; Sitosterols; Taurocholic Acid

2007
Sitosterol xanthomatosis.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2007, Volume: 21, Issue:1

    Topics: Azetidines; Ezetimibe; Female; Humans; Hypolipidemic Agents; Middle Aged; Sitosterols; Xanthomatosis

2007
Madin-Darby canine kidney II cells: a pharmacologically validated system for NPC1L1-mediated cholesterol uptake.
    Molecular pharmacology, 2008, Volume: 73, Issue:4

    Topics: Animals; Azetidines; beta-Lactams; Caco-2 Cells; Cell Line; Cholesterol; Cloning, Molecular; Dogs; Ezetimibe; Humans; Membrane Proteins; Membrane Transport Proteins; Reproducibility of Results; Sitosterols; Sulfonamides; Transfection; Tritium

2008
The natural history of phytosterolemia: Observations on its homeostasis.
    Atherosclerosis, 2018, Volume: 269

    Topics: Adolescent; Adult; Age Factors; Anticholesteremic Agents; Asymptomatic Diseases; ATP Binding Cassette Transporter, Subfamily G, Member 8; Biomarkers; Canada; Child; Child, Preschool; Cholesterol; Ezetimibe; Female; Genetic Predisposition to Disease; Homeostasis; Humans; Hypercholesterolemia; Infant; Intestinal Diseases; Lipid Metabolism, Inborn Errors; Male; Middle Aged; Mutation; Phenotype; Phytosterols; Prevalence; Puberty; Rare Diseases; Risk Factors; Sitosterols; Time Factors; Treatment Outcome; United States; Young Adult

2018
Baseline serum sitosterol level as predictor of adverse clinical events in acute coronary syndrome patients with dyslipidaemia: A sub-analysis of HIJ-PROPER.
    Atherosclerosis, 2018, Volume: 274

    Topics: Acute Coronary Syndrome; Aged; Biomarkers; Cholesterol, LDL; Dyslipidemias; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Japan; Male; Middle Aged; Predictive Value of Tests; Quinolines; Randomized Controlled Trials as Topic; Retrospective Studies; Risk Assessment; Risk Factors; Sitosterols; Time Factors; Treatment Outcome

2018
A case of ezetimibe-effective hypercholesterolemia with a novel heterozygous variant in ABCG5.
    Endocrine journal, 2020, Nov-28, Volume: 67, Issue:11

    Topics: Anticholesteremic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 5; Cholesterol; Cholesterol, LDL; Diagnostic Errors; Ezetimibe; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hyperlipoproteinemia Type II; Intestinal Diseases; Lipid Metabolism, Inborn Errors; Lipoproteins; Loss of Function Mutation; Middle Aged; Phytosterols; Sitosterols; Treatment Failure

2020