Page last updated: 2024-09-04

ezetimibe and erlotinib

ezetimibe has been researched along with erlotinib in 3 studies

Compound Research Comparison

Studies
(ezetimibe)
Trials
(ezetimibe)
Recent Studies (post-2010)
(ezetimibe)
Studies
(erlotinib)
Trials
(erlotinib)
Recent Studies (post-2010) (erlotinib)
2,4845631,4652210180

Protein Interaction Comparison

ProteinTaxonomyezetimibe (IC50)erlotinib (IC50)
epidermal growth factor receptor isoform a precursorHomo sapiens (human)0.001
Cyclin-G-associated kinaseHomo sapiens (human)0.474
Tyrosine-protein kinase JAK2Homo sapiens (human)4
Solute carrier organic anion transporter family member 2B1 Homo sapiens (human)0.55
Bile salt export pumpHomo sapiens (human)10
Proto-oncogene tyrosine-protein kinase SrcGallus gallus (chicken)0.99
Epidermal growth factor receptorHomo sapiens (human)0.5294
Receptor tyrosine-protein kinase erbB-2Homo sapiens (human)0.7171
Cytochrome P450 3A4Homo sapiens (human)0.016
Platelet-derived growth factor receptor betaHomo sapiens (human)0.0122
Serine/threonine-protein kinase B-rafHomo sapiens (human)0.06
Corticosteroid 11-beta-dehydrogenase isozyme 1 Rattus norvegicus (Norway rat)0.03
Platelet-derived growth factor receptor alphaHomo sapiens (human)8.12
Vascular endothelial growth factor receptor 1 Homo sapiens (human)0.25
Receptor tyrosine-protein kinase erbB-3Homo sapiens (human)0.2586
Sodium-dependent dopamine transporterRattus norvegicus (Norway rat)0.369
Cyclin-dependent kinase 2Homo sapiens (human)1.14
Adenosine receptor A1Rattus norvegicus (Norway rat)0.0063
Serine/threonine-protein kinase B-raf Mus musculus (house mouse)0.06
Cytochrome P450 2C19Homo sapiens (human)0.087
Vascular endothelial growth factor receptor 3Homo sapiens (human)0.25
Vascular endothelial growth factor receptor 2Homo sapiens (human)0.8349
D(1A) dopamine receptorSus scrofa (pig)0.3
Fatty-acid amide hydrolase 1Rattus norvegicus (Norway rat)0.0095
Synaptic vesicular amine transporterRattus norvegicus (Norway rat)0.001
Focal adhesion kinase 1Homo sapiens (human)7.4
Receptor tyrosine-protein kinase erbB-4Homo sapiens (human)0.6925
Canalicular multispecific organic anion transporter 1Homo sapiens (human)10
Alpha-1A adrenergic receptor Sus scrofa (pig)0.3
Serine/threonine-protein kinase TBK1Homo sapiens (human)2.2
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)0.13

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Chellappan, DK; Collet, TA; Dighe, SN; Dua, K; Ekwudu, O; Katavic, PL1

Reviews

2 review(s) available for ezetimibe and erlotinib

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Recent update on anti-dengue drug discovery.
    European journal of medicinal chemistry, 2019, Aug-15, Volume: 176

    Topics: Animals; Antiviral Agents; Biological Products; Cell Line, Tumor; Dengue Virus; Drug Discovery; Humans; Serine Proteinase Inhibitors; Viral Nonstructural Proteins; Virus Replication

2019

Other Studies

1 other study(ies) available for ezetimibe and erlotinib

ArticleYear
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012