Page last updated: 2024-09-04

ezetimibe and eplerenone

ezetimibe has been researched along with eplerenone in 3 studies

Compound Research Comparison

Studies (ezetimibe)	Trials (ezetimibe)	Recent Studies (post-2010) (ezetimibe)	Studies (eplerenone)	Trials (eplerenone)	Recent Studies (post-2010) (eplerenone)
2,484	563	1,465	1,036	172	577

Protein Interaction Comparison

Protein	Taxonomy	ezetimibe (IC50)	eplerenone (IC50)
Mineralocorticoid receptor	Homo sapiens (human)		0.668
Mineralocorticoid receptor	Rattus norvegicus (Norway rat)		0.0398

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (33.33)	29.6817
2010's	2 (66.67)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1

Reviews

1 review(s) available for ezetimibe and eplerenone

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Other Studies

2 other study(ies) available for ezetimibe and eplerenone

Article	Year
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Avoid the risks of mixed medications. How to minimize dangerous interactions with cardiovascular drugs. Heart advisor, 2003, Volume: 6, Issue:11 Topics: Anticholesteremic Agents; Azetidines; Cardiovascular Agents; Drug Interactions; Eplerenone; Ezetimibe; Fluorobenzenes; Humans; Polypharmacy; Pyrimidines; Rosuvastatin Calcium; Spironolactone; Sulfonamides	2003

Article

Year

A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.

Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013

Avoid the risks of mixed medications. How to minimize dangerous interactions with cardiovascular drugs.

Heart advisor, 2003, Volume: 6, Issue:11

Topics: Anticholesteremic Agents; Azetidines; Cardiovascular Agents; Drug Interactions; Eplerenone; Ezetimibe; Fluorobenzenes; Humans; Polypharmacy; Pyrimidines; Rosuvastatin Calcium; Spironolactone; Sulfonamides

2003