ezetimibe has been researched along with efavirenz in 7 studies
| Studies (ezetimibe) | Trials (ezetimibe) | Recent Studies (post-2010) (ezetimibe) | Studies (efavirenz) | Trials (efavirenz) | Recent Studies (post-2010) (efavirenz) |
|---|---|---|---|---|---|
| 2,484 | 563 | 1,465 | 3,110 | 631 | 1,611 |
| Protein | Taxonomy | ezetimibe (IC50) | efavirenz (IC50) |
|---|---|---|---|
| Chain A, POL POLYPROTEIN | Human immunodeficiency virus 1 | 0.2612 | |
| Chain A, POL POLYPROTEIN | Human immunodeficiency virus 1 | 0.2612 | |
| Chain B, POL POLYPROTEIN | Human immunodeficiency virus 1 | 0.2612 | |
| Chain A, POL POLYPROTEIN | Human immunodeficiency virus 1 | 0.2612 | |
| Chain B, POL POLYPROTEIN | Human immunodeficiency virus 1 | 0.2612 | |
| Chain A, Pol Polyprotein | Human immunodeficiency virus 1 | 0.2612 | |
| Chain B, Pol Polyprotein | Human immunodeficiency virus 1 | 0.2612 | |
| Prothrombin | Bos taurus (cattle) | 0.022 | |
| Gag-Pol polyprotein | HIV-1 M:B_HXB2R | 0.1852 | |
| Gag-Pol polyprotein | Human immunodeficiency virus type 1 (NEW YORK-5 ISOLATE) | 0.02 | |
| Kappa-type opioid receptor | Cavia porcellus (domestic guinea pig) | 0.018 | |
| Microsomal triglyceride transfer protein large subunit | Homo sapiens (human) | 0.054 | |
| Disintegrin and metalloproteinase domain-containing protein 17 | Homo sapiens (human) | 0.004 | |
| Envelope glycoprotein gp160 [Cleaved into: Surface protein gp120 | Human immunodeficiency virus 1 | 0.0035 | |
| Reverse transcriptase/RNaseH | Human immunodeficiency virus 1 | 0.1627 | |
| Reverse transcriptase | Human immunodeficiency virus 1 | 0.0643 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 7 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Desta, Z; Hubeny, A; Jia, J; Keiser, M; Kroemer, HK; Lütjohann, D; Marinova, M; Meyer zu Schwabedissen, HE; Modess, C; Mostertz, J; Nassif, A; Ogburn, ET; Oswald, S; Runge, D; Siegmund, W; Ulrich, A | 1 |
| Bresser, C; Desta, Z; Kroemer, HK; Lütjohann, D; Marinova, M; Meyer zu Schwabedissen, HE; Modess, C; Nassif, A; Nauck, M; Ogburn, ET; Oswald, S; Siegmund, W; Spielhagen, C | 1 |
| Bach, R; Ball, R; Crespo, A; Cuff, JF; Da, C; Gong, X; Lee, CH; Sherer, EC; Shpungin, J; Welch, CJ | 1 |
1 review(s) available for ezetimibe and efavirenz
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
1 trial(s) available for ezetimibe and efavirenz
| Article | Year |
|---|---|
Impact of efavirenz on intestinal metabolism and transport: insights from an interaction study with ezetimibe in healthy volunteers.
Topics: Adult; Alkynes; Animals; Anticholesteremic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azetidines; Benzoxazines; Biological Transport; Cell Line; Cell Line, Transformed; Cyclopropanes; Cytochrome P-450 CYP3A; Dogs; Drug Interactions; Ezetimibe; Gene Expression; Glucuronosyltransferase; HEK293 Cells; HIV Infections; Humans; Hypercholesterolemia; Intestinal Absorption; Intestinal Mucosa; Intestines; Liver; Liver-Specific Organic Anion Transporter 1; Male; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Organic Anion Transporters; RNA, Messenger; Young Adult | 2012 |
5 other study(ies) available for ezetimibe and efavirenz
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Compartment-specific gene regulation of the CAR inducer efavirenz in vivo.
Topics: Adult; Alkynes; Anticholesteremic Agents; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Azetidines; Benzoxazines; Biopsy; Constitutive Androstane Receptor; Cyclopropanes; Cytochrome P-450 CYP2B6; Drug Interactions; Drug Monitoring; Duodenum; Ezetimibe; Gene Expression Regulation; Humans; Inactivation, Metabolic; Leukocytes, Mononuclear; Liver; Male; Oxidoreductases, N-Demethylating; Receptors, Cytoplasmic and Nuclear; Reverse Transcriptase Inhibitors | 2012 |
Systematic approach to conformational sampling for assigning absolute configuration using vibrational circular dichroism.
Topics: Alkynes; Aprepitant; Azetidines; Benzoxazines; Camphor; Circular Dichroism; Computational Biology; Cyclohexane Monoterpenes; Cyclopropanes; Drug Discovery; Ezetimibe; Ibuprofen; Molecular Conformation; Monoterpenes; Morpholines; Pharmaceutical Preparations; Quantum Theory; Simvastatin; Statistical Distributions; Stereoisomerism | 2014 |