Compounds > ezetimibe
Page last updated: 2024-09-04

ezetimibe and d-alpha tocopherol

ezetimibe has been researched along with d-alpha tocopherol in 9 studies

Compound Research Comparison

Studies
(ezetimibe)		Trials
(ezetimibe)		Recent Studies (post-2010)
(ezetimibe)		Studies
(d-alpha tocopherol)		Trials
(d-alpha tocopherol)		Recent Studies (post-2010) (d-alpha tocopherol)
2,4845631,46532,1982,9037,258

Protein Interaction Comparison

ProteinTaxonomyezetimibe (IC50)d-alpha tocopherol (IC50)
Glutathione S-transferase PHomo sapiens (human)0.5

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (11.11)29.6817
2010's8 (88.89)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Narushima, K; Suzuki, H; Takada, T; Yamanashi, Y1
Abuasal, B; Kaddoumi, A; Sylvester, PW1
Bott, R; Cantiello, M; Collet, X; Coméra, C; Goncalves, A; Nauze, M; Reboul, E; Soayfane, Z; Tercé, F1
Abuasal, BS; Kaddoumi, A; Qosa, H; Sylvester, PW1
Herbas, MS; Ishida, N; Kume, A; Shichiri, M; Suzuki, H1
Nashimoto, S; Sato, Y; Sugawara, M; Takekuma, Y1
Haraguchi, M; Kamishikiryo, J; Morita, T; Nakamura, T; Nakashima, S; Narahara, H; Sugihara, N; Tasaka, Y1

Reviews

1 review(s) available for ezetimibe and d-alpha tocopherol

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

8 other study(ies) available for ezetimibe and d-alpha tocopherol

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Niemann-pick C1-like 1 mediates alpha-tocopherol transport.
    Molecular pharmacology, 2008, Volume: 74, Issue:1

    Topics: alpha-Tocopherol; Animals; Anticholesteremic Agents; Azetidines; Biological Transport; Caco-2 Cells; Cholesterol; Cyclosporine; Ezetimibe; Humans; Immunohistochemistry; Intestinal Absorption; Male; Membrane Proteins; Membrane Transport Proteins; Micelles; Phosphatidylcholines; Rats; Rats, Wistar; Taurocholic Acid; Temperature; Time Factors; Vitamin A

2008
Intestinal absorption of gamma-tocotrienol is mediated by Niemann-Pick C1-like 1: in situ rat intestinal perfusion studies.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:6

    Topics: Animals; Anticholesteremic Agents; Azetidines; Biological Transport; Chromans; Ezetimibe; Ileum; Intestinal Absorption; Intestinal Mucosa; Jejunum; Male; Niemann-Pick Diseases; Perfusion; Rats; Rats, Sprague-Dawley; Vitamin E

2010
Respective contributions of intestinal Niemann-Pick C1-like 1 and scavenger receptor class B type I to cholesterol and tocopherol uptake: in vivo v. in vitro studies.
    The British journal of nutrition, 2012, Volume: 107, Issue:9

    Topics: 4-Chloro-7-nitrobenzofurazan; Absorption; Animals; Azetidines; Bile Acids and Salts; Caco-2 Cells; Cell Membrane; Cholesterol; Chromatography, High Pressure Liquid; Cyclopentanes; Duodenum; Ezetimibe; gamma-Tocopherol; Gene Expression Profiling; Gene Expression Regulation; Humans; Jejunum; Lipid Metabolism; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Micelles; Scavenger Receptors, Class B; Thiosemicarbazones; Time Factors; Vitamin E

2012
Comparison of the intestinal absorption and bioavailability of γ-tocotrienol and α-tocopherol: in vitro, in situ and in vivo studies.
    Biopharmaceutics & drug disposition, 2012, Volume: 33, Issue:5

    Topics: Administration, Oral; alpha-Tocopherol; Animals; Area Under Curve; Azetidines; Biological Availability; Corn Oil; Drug Carriers; Ezetimibe; gamma-Tocopherol; In Vitro Techniques; Injections, Intravenous; Intestinal Absorption; Intestine, Small; Lipolysis; Male; Membrane Transport Proteins; Molecular Structure; Perfusion; Permeability; Rats; Rats, Sprague-Dawley; Solubility

2012
Effect of anti-hyperlipidemia drugs on the alpha-tocopherol concentration and their potential for murine malaria infection.
    Parasitology research, 2016, Volume: 115, Issue:1

    Topics: alpha-Tocopherol; Animals; Anticholesteremic Agents; Antimalarials; Berberine; Cholestyramine Resin; Ezetimibe; Female; Malaria; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Parasitemia; Plasmodium yoelii; Probucol; Specific Pathogen-Free Organisms; Vitamin E Deficiency

2016
Inhibitory effect of ezetimibe can be prevented by an administration interval of 4 h between α-tocopherol and ezetimibe.
    Biopharmaceutics & drug disposition, 2017, Volume: 38, Issue:4

    Topics: alpha-Tocopherol; Animals; Anticholesteremic Agents; Antioxidants; Area Under Curve; Ezetimibe; Intestinal Absorption; Liver; Male; Rats; Rats, Wistar; Tissue Distribution

2017
N-terminal domain of the cholesterol transporter Niemann-Pick C1-like 1 (NPC1L1) is essential for α-tocopherol transport.
    Biochemical and biophysical research communications, 2017, 04-29, Volume: 486, Issue:2

    Topics: alpha-Tocopherol; Animals; Anticholesteremic Agents; Binding, Competitive; Biological Transport; Caco-2 Cells; Cell Line, Tumor; Cholesterol; Endocytosis; Escherichia coli; Ezetimibe; Gene Expression; Genes, Reporter; Green Fluorescent Proteins; Hepatocytes; Humans; Membrane Proteins; Membrane Transport Proteins; Plasmids; Protein Binding; Protein Domains; Rats; Recombinant Fusion Proteins

2017