Page last updated: 2024-09-03

exp7711 and l 158809

exp7711 has been researched along with l 158809 in 4 studies

Compound Research Comparison

Studies
(exp7711)
Trials
(exp7711)
Recent Studies (post-2010)
(exp7711)
Studies
(l 158809)
Trials
(l 158809)
Recent Studies (post-2010) (l 158809)
180113707

Protein Interaction Comparison

ProteinTaxonomyexp7711 (IC50)l 158809 (IC50)
Type-1A angiotensin II receptor Rattus norvegicus (Norway rat)0.0021
Type-1B angiotensin II receptorRattus norvegicus (Norway rat)0.0012
Type-1 angiotensin II receptorHomo sapiens (human)0.0015
Type-1 angiotensin II receptorOryctolagus cuniculus (rabbit)0.0003
Type-2 angiotensin II receptorRattus norvegicus (Norway rat)0.0021
Type-2 angiotensin II receptorHomo sapiens (human)0.0002
5-hydroxytryptamine receptor 1AMus musculus (house mouse)0.0021

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (50.00)18.2507
2000's1 (25.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ashton, WT; Cantone, CL; Chang, LL; Chang, RS; Chen, TB; Faust, KA; Hutchins, SM; Lotti, VJ; MacCoss, M; Strelitz, RA1
Goldberg, MR; Greenlee, WJ; Irvin, JD; Prendergast, K; Smith, RD; Timmermans, PB; Wexler, RR1
Berellini, G; Cruciani, G; Mannhold, R1
Meanwell, NA1

Reviews

1 review(s) available for exp7711 and l 158809

ArticleYear
Nonpeptide angiotensin II receptor antagonists: the next generation in antihypertensive therapy.
    Journal of medicinal chemistry, 1996, Feb-02, Volume: 39, Issue:3

    Topics: Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Humans; Receptors, Angiotensin; Structure-Activity Relationship

1996

Other Studies

3 other study(ies) available for exp7711 and l 158809

ArticleYear
Nonpeptide angiotensin II antagonists derived from 4H-1,2,4-triazoles and 3H-imidazo[1,2-b][1,2,4]triazoles.
    Journal of medicinal chemistry, 1993, Mar-05, Volume: 36, Issue:5

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta; Binding, Competitive; Blood Pressure; Male; Molecular Structure; Rabbits; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Structure-Activity Relationship; Triazoles

1993
Pharmacophore, drug metabolism, and pharmacokinetics models on non-peptide AT1, AT2, and AT1/AT2 angiotensin II receptor antagonists.
    Journal of medicinal chemistry, 2005, Jun-30, Volume: 48, Issue:13

    Topics: Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Binding Sites; Biphenyl Compounds; Kinetics; Losartan; Models, Molecular; Molecular Conformation; Oxidation-Reduction; Pharmaceutical Preparations; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Structure-Activity Relationship; Tetrazoles

2005
Synopsis of some recent tactical application of bioisosteres in drug design.
    Journal of medicinal chemistry, 2011, Apr-28, Volume: 54, Issue:8

    Topics: Cytochrome P-450 Enzyme System; Drug Design

2011