Page last updated: 2024-09-02

exp3174 and itraconazole

exp3174 has been researched along with itraconazole in 2 studies

Compound Research Comparison

Studies
(exp3174)
Trials
(exp3174)
Recent Studies (post-2010)
(exp3174)
Studies
(itraconazole)
Trials
(itraconazole)
Recent Studies (post-2010) (itraconazole)
23629436,4406532,357

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kaukonen, KM; Neuvonen, PJ; Olkkola, KT1
Srinivas, NR1

Trials

2 trial(s) available for exp3174 and itraconazole

ArticleYear
Fluconazole but not itraconazole decreases the metabolism of losartan to E-3174.
    European journal of clinical pharmacology, 1998, Volume: 53, Issue:6

    Topics: Adult; Antifungal Agents; Antihypertensive Agents; Aryl Hydrocarbon Hydroxylases; Cross-Over Studies; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Double-Blind Method; Drug Interactions; Female; Fluconazole; Humans; Imidazoles; Itraconazole; Losartan; Male; Mixed Function Oxygenases; Reference Values; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Tetrazoles

1998
Prediction of area under the curve for a p-glycoprotein, a CYP3A4 and a CYP2C9 substrate using a single time point strategy: assessment using fexofenadine, itraconazole and losartan and metabolites.
    Drug development and industrial pharmacy, 2016, Volume: 42, Issue:6

    Topics: Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cross-Over Studies; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP3A; Drug Interactions; Humans; Itraconazole; Losartan; Polypharmacy; Terfenadine

2016