eugenosedin-a has been researched along with isoeugenol* in 1 studies
1 other study(ies) available for eugenosedin-a and isoeugenol
Article | Year |
---|---|
Efficiency comparison of an isoeugenol-derivated compound, eugenosedin-A, with glibenclamide and pioglitazone in protecting cardiovascular dysfunction of diabetic SHR.
This study was to investigate three agents possible protective effect against DM-induced cardiovascular dysfunction in spontaneously hypertensive rats (SHR). Control group was fed normal diet, DM group was injected with STZ/NA and fed high fat diet (HFD), and treatment groups were given STZ/NA, fed HFD, and then oral gavaged with eugenosedin-A (Eu-A), glibenclamide (Gli), or pioglitazone (Pio) 5 mg/kg/per day for 4-week, respectively. Eu-A, Gli, and Pio clearly ameliorated the changes of body weight, cardiac weight, and the biochemical parameters, cardiovascular disorders and inflammation. Like Gli and Pio, Eu-A may be effectively to control DM and the cardiovascular dysfunction. Topics: Animals; Diabetes Mellitus, Experimental; Glyburide; Hypoglycemic Agents; Pioglitazone; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley | 2023 |