eudistomin-u has been researched along with tryptamine* in 1 studies
1 other study(ies) available for eudistomin-u and tryptamine
| Article | Year |
|---|---|
[Synthesis of 1-indole substituted beta-carboline alkaloid and its derivatives and evaluation of their preliminary antitumor activities].
To synthesize eudistomin U and its 6-OCH3/Br derivatives and 5'-Br derivatives as antitumor agents.. Using tryptamine and indole-3-aldehyde as starting materials, through condensation, Pictet-Spengler cyclization and dehydrogenation three steps, the alkaloids and its derivatives were prepared.. The structures of the compounds were determined by 1HNMR, MS and HRMS. Antitumor activity in vitro was tested.. Eudistomin U and its derivatives were synthesized. The results showed that they all showed antitumor activities against mouse P388 strain. Topics: Alkaloids; Animals; Antineoplastic Agents; Carbolines; Cell Division; Cell Line, Tumor; Indoles; Leukemia P388; Mice; Molecular Structure; Tryptamines | 2004 |