Page last updated: 2024-09-05

etravirine and l 737126

etravirine has been researched along with l 737126 in 2 studies

Compound Research Comparison

Studies (etravirine)	Trials (etravirine)	Recent Studies (post-2010) (etravirine)	Studies (l 737126)	Trials (l 737126)	Recent Studies (post-2010) (l 737126)
572	90	321	10	0	2

Protein Interaction Comparison

Protein	Taxonomy	l 737126 (IC50)
Gag-Pol polyprotein	HIV-1 M:B_HXB2R	0.075
Reverse transcriptase/RNaseH	Human immunodeficiency virus 1	0.0707
Protease	Human immunodeficiency virus 1	0.0875

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	1 (50.00)	24.3611
2020's	1 (50.00)	2.80

Authors

Authors	Studies
De Clercq, E; Li, D; Liu, X; Zhan, P	1
Armijos Rivera, JI; Badia, R; Brambilla, A; Catalano, M; Cinquina, E; Coluccia, A; Crespan, E; Esté, JA; Falasca, F; La Regina, G; Limatola, C; Maga, G; Masci, D; Nalli, M; Riveira-Muñoz, E; Silvestri, R; Turriziani, O	1

Other Studies

2 other study(ies) available for etravirine and l 737126

Article	Year
Strategies for the design of HIV-1 non-nucleoside reverse transcriptase inhibitors: lessons from the development of seven representative paradigms. Journal of medicinal chemistry, 2012, Apr-26, Volume: 55, Issue:8 Topics: Anti-HIV Agents; Benzodiazepines; Binding Sites; Crystallography, X-Ray; Drug Design; HIV Reverse Transcriptase; HIV-1; Hydrogen Bonding; Imidazoles; Indoles; Nitriles; Reverse Transcriptase Inhibitors; Structure-Activity Relationship	2012
New indolylarylsulfone non-nucleoside reverse transcriptase inhibitors show low nanomolar inhibition of single and double HIV-1 mutant strains. European journal of medicinal chemistry, 2020, Dec-15, Volume: 208 Topics: Anti-HIV Agents; Cell Line, Tumor; Drug Design; Drug Synergism; HIV Reverse Transcriptase; HIV-1; Humans; Indoles; Microbial Sensitivity Tests; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Structure; Mutation; Protein Binding; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Sulfones; Zidovudine	2020

Article

Year

Strategies for the design of HIV-1 non-nucleoside reverse transcriptase inhibitors: lessons from the development of seven representative paradigms.

Journal of medicinal chemistry, 2012, Apr-26, Volume: 55, Issue:8

Topics: Anti-HIV Agents; Benzodiazepines; Binding Sites; Crystallography, X-Ray; Drug Design; HIV Reverse Transcriptase; HIV-1; Hydrogen Bonding; Imidazoles; Indoles; Nitriles; Reverse Transcriptase Inhibitors; Structure-Activity Relationship

2012

New indolylarylsulfone non-nucleoside reverse transcriptase inhibitors show low nanomolar inhibition of single and double HIV-1 mutant strains.

European journal of medicinal chemistry, 2020, Dec-15, Volume: 208

Topics: Anti-HIV Agents; Cell Line, Tumor; Drug Design; Drug Synergism; HIV Reverse Transcriptase; HIV-1; Humans; Indoles; Microbial Sensitivity Tests; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Structure; Mutation; Protein Binding; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Sulfones; Zidovudine

2020