Compounds > etravirine
Page last updated: 2024-09-05

etravirine and itraconazole

etravirine has been researched along with itraconazole in 4 studies

Compound Research Comparison

Studies
(etravirine)		Trials
(etravirine)		Recent Studies (post-2010)
(etravirine)		Studies
(itraconazole)		Trials
(itraconazole)		Recent Studies (post-2010) (itraconazole)
572903212494108
572903216,4406532,357

Protein Interaction Comparison

ProteinTaxonomyetravirine (IC50)itraconazole (IC50)
Tyrosine-protein kinase FynHomo sapiens (human)3.89
ATP-dependent translocase ABCB1Mus musculus (house mouse)0.7
ATP-dependent translocase ABCB1Homo sapiens (human)1.666
Cytochrome P450 3A4Homo sapiens (human)0.4256
ATP-dependent translocase ABCB1Mus musculus (house mouse)0.2
C-X-C chemokine receptor type 1Homo sapiens (human)2.5676
CruzipainTrypanosoma cruzi3
Vasopressin V2 receptorHomo sapiens (human)3.476
C-C chemokine receptor type 4Homo sapiens (human)3.2689
Lanosterol 14-alpha demethylaseHomo sapiens (human)3.6
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)2

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (50.00)24.3611
2020's2 (50.00)2.80

Authors

AuthorsStudies
Doak, AK; Prusiner, SB; Shoichet, BK; Wille, H1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Appeltans, B; Pas, T; Van den Mooter, G; Verbert, S1

Reviews

1 review(s) available for etravirine and itraconazole

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

3 other study(ies) available for etravirine and itraconazole

ArticleYear
Colloid formation by drugs in simulated intestinal fluid.
    Journal of medicinal chemistry, 2010, May-27, Volume: 53, Issue:10

    Topics: Buffers; Chemical Precipitation; Colloids; Intestine, Small; Light; Microscopy, Electron, Transmission; Pharmaceutical Preparations; Scattering, Radiation; Solubility

2010
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
The influence of crushing amorphous solid dispersion dosage forms on the in-vitro dissolution kinetics.
    International journal of pharmaceutics, 2020, Jan-05, Volume: 573

    Topics: Administration, Oral; Antifungal Agents; Antiviral Agents; Biological Availability; Chemistry, Pharmaceutical; Crystallization; Drug Compounding; Drug Liberation; Equivalence Trials as Topic; Itraconazole; Nitriles; Particle Size; Pyridazines; Pyrimidines; Research Design; Ritonavir; Solubility; Therapeutic Equivalency; Triazoles; X-Ray Diffraction

2020