etravirine has been researched along with dextromethorphan in 3 studies
| Studies (etravirine) | Trials (etravirine) | Recent Studies (post-2010) (etravirine) | Studies (dextromethorphan) | Trials (dextromethorphan) | Recent Studies (post-2010) (dextromethorphan) |
|---|---|---|---|---|---|
| 572 | 90 | 321 | 2,020 | 342 | 593 |
| Protein | Taxonomy | etravirine (IC50) | dextromethorphan (IC50) |
|---|---|---|---|
| Sodium channel protein type 1 subunit alpha | Rattus norvegicus (Norway rat) | 1.3 | |
| Sodium channel protein type 2 subunit alpha | Rattus norvegicus (Norway rat) | 1.3 | |
| Sodium channel protein type 3 subunit alpha | Rattus norvegicus (Norway rat) | 1.3 | |
| Cytochrome P450 2D26 | Rattus norvegicus (Norway rat) | 5.6 | |
| Cytochrome P450 2D6 | Homo sapiens (human) | 2.1768 | |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | 0.0027 | |
| Sigma non-opioid intracellular receptor 1 | Cavia porcellus (domestic guinea pig) | 0.1236 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Chen, FE; Clercq, E; Hao, QQ; Ling, X; Pannecouque, C | 1 |
| Aharchi, F; De Smedt, G; Hoetelmans, RM; Kakuda, TN; Leopold, L; Onkelinx, J; Peeters, M; Stevens, T; Van Solingen-Ristea, RM | 1 |
1 review(s) available for etravirine and dextromethorphan
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
1 trial(s) available for etravirine and dextromethorphan
| Article | Year |
|---|---|
The effect of single- and multiple-dose etravirine on a drug cocktail of representative cytochrome P450 probes and digoxin in healthy subjects.
Topics: Adolescent; Adult; Anti-HIV Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caffeine; Cross-Over Studies; Cytochrome P-450 Enzyme System; Dextromethorphan; Digoxin; Female; Healthy Volunteers; Humans; Male; Midazolam; Middle Aged; Nitriles; Omeprazole; Pyridazines; Pyrimidines; Reverse Transcriptase Inhibitors; Theophylline; Warfarin; Young Adult | 2014 |
1 other study(ies) available for etravirine and dextromethorphan
| Article | Year |
|---|---|
Expansion of the S-CN-DABO scaffold to exploit the impact on inhibitory activities against the non-nucleoside HIV-1 reverse transcriptase.
Topics: Animals; Anti-HIV Agents; HIV Reverse Transcriptase; HIV-1; Mice; Molecular Docking Simulation; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Inhibitors; Structure-Activity Relationship | 2022 |