Page last updated: 2024-09-05

etravirine and abacavir

etravirine has been researched along with abacavir in 12 studies

Compound Research Comparison

Studies (etravirine)	Trials (etravirine)	Recent Studies (post-2010) (etravirine)	Studies (abacavir)	Trials (abacavir)	Recent Studies (post-2010) (abacavir)
572	90	321	1,280	240	453

Protein Interaction Comparison

Protein	Taxonomy	etravirine (IC50)	abacavir (IC50)
Reverse transcriptase/RNaseH	Human immunodeficiency virus 1		0.13

Research

Studies (12)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	2 (16.67)	29.6817
2010's	6 (50.00)	24.3611
2020's	4 (33.33)	2.80

Authors

Authors	Studies
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M	1
Danner, SA; Gruzdev, B; Jurriaans, S; Lange, JM; Peeters, M; Prins, JM; Rakhmanova, A; Sankatsing, SU; van't Klooster, G; Weverling, GJ	1
Boyle, BA; Cohen, CJ; Elion, R; Frank, I; Moyle, GJ; Sax, P	1
Dronda, F; García-Blázquez, V; Lourido-García, D; Vicente-Bártulos, A	1
Carleo, MA; Chirianni, A; Coppola, N; De Luca, A; Esposito, V; Guerra, G; Lucariello, A; Perna, A; Sangiovanni, V; Viglietti, R	1
Dunn, KJ; Kagan, RM; Kaufman, HW; Nettles, RE; Snell, GP	1
Bonora, S; Calcagno, A; De Benedetto, I; Guastamacchia, G; Trunfio, M	1
Hamzah, L; Post, FA	1
Bolanowski, M; Domrazek, K; Dziewiszek, W; Eberhardt, M; Heinrich, A; Jawień, P; Jędrzejuk, D; Jęśkowiak, I; Kwiatkowska, J; Matuszewska, A; Merwid-Ląd, A; Nikodem, A; Niżański, W; Nowak, B; Olejnik, K; Piotrowska, A; Podhorska-Okołów, M; Rutkowska, M; Sozański, T; Szeląg, A; Szeląg, E; Tomkalski, T; Wiatrak, B; Zduniak, K	1

Reviews

2 review(s) available for etravirine and abacavir

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
A review of the potential mechanisms of neuronal toxicity associated with antiretroviral drugs. Journal of neurovirology, 2020, Volume: 26, Issue:5 Topics: Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Astrocytes; Atazanavir Sulfate; Benzoxazines; Central Nervous System; Cognitive Dysfunction; Cyclopropanes; Dideoxynucleosides; Endothelial Cells; HIV Infections; Humans; Neurons; Nevirapine; Nitriles; Oligodendroglia; Pyrimidines	2020

Article

Year

DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.

Drug discovery today, 2016, Volume: 21, Issue:4

Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

A review of the potential mechanisms of neuronal toxicity associated with antiretroviral drugs.

Journal of neurovirology, 2020, Volume: 26, Issue:5

Topics: Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Astrocytes; Atazanavir Sulfate; Benzoxazines; Central Nervous System; Cognitive Dysfunction; Cyclopropanes; Dideoxynucleosides; Endothelial Cells; HIV Infections; Humans; Neurons; Nevirapine; Nitriles; Oligodendroglia; Pyrimidines

2020

Trials

1 trial(s) available for etravirine and abacavir

Article	Year
TMC125 exerts similar initial antiviral potency as a five-drug, triple class antiretroviral regimen. AIDS (London, England), 2003, Dec-05, Volume: 17, Issue:18 Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Dideoxynucleosides; Double-Blind Method; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Male; Nevirapine; Nitriles; Pyridazines; Pyrimidines; Reverse Transcriptase Inhibitors; RNA, Viral; Treatment Outcome; Zidovudine	2003

Article

Year

TMC125 exerts similar initial antiviral potency as a five-drug, triple class antiretroviral regimen.

AIDS (London, England), 2003, Dec-05, Volume: 17, Issue:18

Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Dideoxynucleosides; Double-Blind Method; Drug Therapy, Combination; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Indinavir; Lamivudine; Male; Nevirapine; Nitriles; Pyridazines; Pyrimidines; Reverse Transcriptase Inhibitors; RNA, Viral; Treatment Outcome; Zidovudine

2003

Other Studies

9 other study(ies) available for etravirine and abacavir

Article	Year
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology. Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3 Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries	2023
Advances in HIV therapeutics: the 14th CROI. The AIDS reader, 2007, Volume: 17, Issue:5 Topics: Acyclovir; Anti-HIV Agents; Circumcision, Male; Cyclohexanes; Dideoxynucleosides; Drug Interactions; Female; Hepatitis C; HIV Fusion Inhibitors; HIV Infections; Humans; Male; Maraviroc; Multicenter Studies as Topic; Nitriles; Organic Chemicals; Pyridazines; Pyrimidines; Pyrrolidinones; Raltegravir Potassium; Randomized Controlled Trials as Topic; Triazoles	2007
HIV treatment information. Project Inform perspective, 2010, Issue:50 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Body Fat Distribution; Cognition; Cyclopropanes; Diabetes Mellitus; Dideoxynucleosides; Ginkgo biloba; Growth Hormone-Releasing Hormone; Heart Diseases; Humans; Nitriles; Pyridazines; Pyrimidines	2010
Recent FDA approvals and changes. AIDS patient care and STDs, 2011, Volume: 25, Issue:2 Topics: Anti-HIV Agents; Child; Controlled Clinical Trials as Topic; Dideoxynucleosides; Drug Approval; Drug Labeling; Female; Growth Hormone-Releasing Hormone; HIV Infections; HIV-Associated Lipodystrophy Syndrome; Humans; Infant; Infant, Newborn; Male; Nitriles; Pyridazines; Pyrimidines; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Stavudine; United States; United States Food and Drug Administration	2011
[Leucoencephalopathy in a patient with type I human immunodeficiency virus (HIV-1) infection and symptoms of a hypertensive emergency]. Enfermedades infecciosas y microbiologia clinica, 2012, Volume: 30, Issue:4 Topics: Adult; Anti-HIV Agents; Brain Edema; Darunavir; Diagnosis, Differential; Dideoxynucleosides; Emergencies; Female; Hepatitis C, Chronic; HIV Infections; HIV-1; Humans; Hypertension, Malignant; Hypertensive Encephalopathy; Leukoencephalopathy, Progressive Multifocal; Magnetic Resonance Imaging; Nitriles; Posterior Leukoencephalopathy Syndrome; Pyridazines; Pyrimidines; Pyrrolidinones; Raltegravir Potassium; Ritonavir; Sulfonamides; Tomography, X-Ray Computed; Toxoplasmosis, Cerebral	2012
Different Impact Of Antiretroviral Drugs On Bone Differentiation In An In Vitro Model. Journal of cellular biochemistry, 2015, Volume: 116, Issue:10 Topics: Alkynes; Antiretroviral Therapy, Highly Active; Benzoxazines; Bone Development; Calcium; Cell Differentiation; Cell Line, Tumor; Collagen Type I; Cyclopropanes; Darunavir; Dideoxynucleosides; Gene Expression Regulation, Developmental; HIV-1; Humans; Nitriles; Osteosarcoma; p21-Activated Kinases; Pyridazines; Pyrimidines; RNA, Messenger; Tenofovir; Wnt3A Protein	2015
Trends in HIV-1 Drug Resistance Mutations from a U.S. Reference Laboratory from 2006 to 2017. AIDS research and human retroviruses, 2019, Volume: 35, Issue:8 Topics: Anti-HIV Agents; Darunavir; Dideoxynucleosides; Drug Resistance, Viral; Genotype; Heterocyclic Compounds, 3-Ring; HIV Infections; HIV Integrase Inhibitors; HIV Protease Inhibitors; HIV-1; Humans; Mutation; Nitriles; Oxazines; Piperazines; Pyridazines; Pyridones; Pyrimidines; Reverse Transcriptase Inhibitors; Rilpivirine	2019
Effect of menopause on weight gain, insulin and waist circumference in women with HIV who switch antiretroviral therapy to abacavir/lamivudine/dolutegravir. AIDS (London, England), 2021, 02-02, Volume: 35, Issue:2 Topics: Dideoxynucleosides; Female; Heterocyclic Compounds, 3-Ring; HIV Infections; Humans; Insulin; Lamivudine; Menopause; Nitriles; Oxazines; Piperazines; Pyridones; Pyrimidines; Raltegravir Potassium; Waist Circumference; Weight Gain	2021
Long-Term Administration of Abacavir and Etravirine Impairs Semen Quality and Alters Redox System and Bone Metabolism in Growing Male Wistar Rats. Oxidative medicine and cellular longevity, 2021, Volume: 2021 Topics: Animals; Anti-HIV Agents; Bone and Bones; Bone Density; Catalase; Dideoxynucleosides; Glutathione; Glutathione Peroxidase; Kidney; Liver; Male; Malondialdehyde; Nitriles; Oxidative Stress; Pyrimidines; Rats; Rats, Wistar; Semen; Superoxide Dismutase; Testis	2021