etorphine has been researched along with naloxone in 148 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 107 (72.30) | 18.7374 |
1990's | 30 (20.27) | 18.2507 |
2000's | 10 (6.76) | 29.6817 |
2010's | 1 (0.68) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Klein, P; Nelson, WL | 1 |
Camerman, A; Camerman, N; Cheng, A; DeGraw, JI; Lawson, JA; Loew, G; Polgar, W; Toll, L; Uyeno, E | 1 |
Portoghese, PS; Takemori, AE | 1 |
Casella, G; Clouet, DH; Mulé, SJ | 1 |
Keane, PE; Neal, H | 1 |
Brandt, M; Glaser, T; Hamprecht, B; Klebensberger, W; Traber, J | 1 |
Blume, AJ; Finberg, JP; Shorr, J; Spector, S | 1 |
Braestrup, C; Squires, RF | 1 |
Macdonald, RL; Nelson, PG | 1 |
Blume, AJ | 1 |
Makman, MH; Walczak, SA; Wilkening, D | 1 |
Anderson, SD; Fields, HL | 1 |
Cho, JS; Cho, TM; Loh, HH; Way, EL | 1 |
Meunier, JC; Zajac, JM | 1 |
Akera, T; Brody, TM; Davis, ME | 1 |
Jukofsky, D; Mulé, SJ; Verebely, K | 1 |
Klee, WA; Nirenberg, M; Sharma, SK | 1 |
Bennett, GJ; Mayer, DJ | 1 |
Patenaude, RP | 1 |
Dum, J; Herz, A; Höllt, V; Meyer, G | 1 |
Yaksh, TL | 1 |
Jacob, JJ; Ramabadran, K | 1 |
Dodman, NH; Waterman, AE | 1 |
Li, CH; Loh, HH; Tseng, LF; Wei, ET | 1 |
Crain, B; Crain, SM; Peterson, ER; Simon, EJ | 1 |
Groth, J; Simon, EJ | 1 |
Guillemin, R; Lazarus, LH; Ling, N | 1 |
Klee, WA; Lampert, A; Nirenberg, M | 1 |
Cox, BM; Goldstein, A; Opheim, KE; Teschemacher, H | 2 |
Bläsig, J; Dum, J; Herz, A; Höllt, V; Schubert, P | 1 |
Smuts, GL | 1 |
Bidlack, JM; Gucker, S | 1 |
Edwards, RH; Evans, CJ; Keith, DE; Magendzo, K; Morrison, H | 1 |
Lianfang, H; Miaozhen, W; Wei-Qiang, D | 1 |
Coghill, RC; Frenk, H; Leshem, M; Mayer, DJ | 1 |
Qin, BY; Wang, DX | 1 |
Kreeger, TJ; Seal, US | 1 |
Katki, AG; Schwarz, S | 1 |
Klein, P; Nelson, WL; Simon, EJ; Yao, YH | 1 |
Bonnet, KA; Edmondson, EA; Friedhoff, AJ | 1 |
Ahmed, MS; Cavinato, AG; Maulik, D; Zhou, DH | 1 |
Jin, YH; Li, BB; Li, LY; Li, MX; Qiu, ZB; Zhu, CL | 1 |
Cross, AJ; Hille, C; Slater, P | 1 |
Attali, B; Saya, D; Vogel, Z | 1 |
Altes, U; Baur, AM; Jost, D; Racké, K; Schäfer, J | 1 |
Bolger, GT; Marcus, KA; Skolnick, P; Thibou, R; Weissman, BA | 1 |
Barnard, EA; Demoliou-Mason, CD; Wong, YH | 1 |
Dixon, WR; Follett, DL; Semafuko, WE | 1 |
Frances, B; Meunier, JC; Moisand, C | 1 |
Barnard, EA; Demoliou-Mason, CD | 1 |
Buder, M; Fuder, H; Riers, HD; Rothacher, G | 1 |
Livett, BG; Marley, PD | 1 |
Adler, MW; Geller, EB; Rowan, CH | 1 |
Huang, XY; Sun, HQ; Sun, JD | 1 |
Li, CH; Nicolas, P | 2 |
Cho, TM; Nozaki, M | 1 |
Bourne, RC; Crow, TJ; Kosterlitz, HW; Owen, F; Paterson, SJ; Poulter, M | 1 |
Holaday, JW; Robles, L; Tortella, FC | 1 |
Costa, T; Gramsch, C; Herz, A; Wüster, M | 1 |
Dufau, ML; Fabbri, A; Fraioli, F; Luna, S; Tsai-Morris, CH | 1 |
Nagy, JI; van der Kooy, D | 1 |
Richards, ML; Sadée, W; Yu, VC | 1 |
Charness, ME; Diamond, I; Querimit, LA | 1 |
Glasel, JA; Pelosi, LA | 1 |
Brown, SR; Cote, TE; Cox, BM; Puttfarcken, P; Werling, LL | 1 |
Glavin, GB; Hnatowich, MR; Kiernan, K; Labella, FS | 1 |
Greenspan, DL; Musacchio, JM | 2 |
Law, PY; Loh, HH; Tao, PL | 1 |
Gardner, EL; Vaysse, PJ; Zukin, RS | 1 |
Catt, KJ; Dufau, ML; Stojilković, SS | 1 |
Braham, E; Brown, D; Leung, MK; Ndubuka, C; Pratt, S; Stefano, GB | 1 |
Schwartz, JP | 1 |
Cheng, JS; Luo, DS | 1 |
Delgoulet, C; Roquebert, J | 1 |
Harris, NC; Ryall, RW | 1 |
Aiello, E; Braham, E; Finn, P; Leung, MK; Stefano, GB | 1 |
Appia, F; Chariot, J; Rozé, C; Vaille, C | 1 |
Griffin, MT; Law, PY; Loh, HH | 1 |
Grevel, J; Richards, ML; Rosenbaum, JS; Sadée, W | 1 |
Franklin, PH; Hoss, W | 1 |
Contreras, PC; Takemori, AE | 1 |
Bianchi, G; Fiocchi, R; Manara, L; Peracchia, F; Petrillo, P; Tavani, A | 1 |
Herkenham, M; Pert, CB | 1 |
Dashwood, MR; Kiang, JG; Wei, ET | 1 |
Herz, A; Schulz, R; Wüster, M | 2 |
Field, M; Kachur, JF; Miller, RJ | 1 |
Groth, J; Hiller, JM; Howells, RD; Simon, EJ | 1 |
Kalant, H; Mucha, RF; Volkovskis, C | 1 |
Herling, S; Medzihradsky, F; Merz, H; Valentino, RJ; Woods, JH | 1 |
Hess, GD; Joseph, JA; Roth, GS | 1 |
Manara, L; Monferini, E; Strada, D | 1 |
Adler, MW; Cowan, A; Tortella, FC | 1 |
Fitz-Syage, ML; Gardner, EL; Gintzler, AR; Sugarman, JR; Zukin, RS; Zukin, SR | 1 |
Tolkovsky, AM | 1 |
Brown, DR; Holtzman, SG; Locke, KW | 1 |
Katz, JL; Medzihradsky, F; Valentino, RJ; Woods, JH | 1 |
Lamki, L; Sullivan, S | 1 |
Garzón, J; Lee, NM; Sánchez-Blázquez, P | 1 |
Musacchio, JM; Schen, C | 1 |
Ahmed, MS | 1 |
Bardo, MT; Bhatnagar, RK; Gebhart, GF | 1 |
Gioannini, TL; Hiller, JM; Itzhak, Y; Simon, EJ | 1 |
Holford, NH; Rosenbaum, JS; Sadée, W | 1 |
Aman, RA; Holford, NH; Richards, ML; Rosenbaum, JS; Sadée, W | 1 |
Clark, SL; Ryall, RW | 1 |
Gambino, MC; Petrillo, P; Tavani, A | 1 |
Assanah, P; Burrowes, WR; Chapman, A; Gonzales, G; Iannone, B; Leung, MK; Stefano, GB | 1 |
Schecter, A | 1 |
DeRossett, SE; Holtzman, SG | 1 |
Fujimoto, JM; Lange, DG; Roerig, SC; Wang, RI | 1 |
Bär, PR; Gispen, WH; Schotman, P | 1 |
Kamei, J; Kasuya, Y; Misawa, M; Nagase, H; Suzuki, T | 1 |
Kaneto, H; Nakamura, F; Takahashi, M; Tokuyama, S | 1 |
Avidor-Reiss, T; Barg, J; Ezra, V; Levy, R; Matus-Leibovitch, N; Saya, D; Vogel, Z; Zippel, R | 1 |
Jauzac, P; Polastron, J | 1 |
Crain, SM; Shen, KF | 2 |
Kaneto, H; Takahashi, M; Tokuyama, S | 1 |
Han, J; Wang, X; Zhang, L | 1 |
Davis, T; Duttaroy, A; Shah, S; Yoburn, BC | 1 |
Billings, B; Duttaroy, A; Yoburn, BC | 1 |
Howells, RD; Jin, J; Shahrestanifar, M; Wang, WW | 1 |
Bertolucci, M; De Simoni, MG; Perego, C | 1 |
Feigenbaum, JJ; Simantov, R | 1 |
Freye, E; Neruda, B; Smith, OW | 1 |
Chen, DH; Miao, H; Qin, BY; Yang, Y | 1 |
Wang, J; Wang, YP | 1 |
Bai, HQ; Li, FY; Li, Y; Wu, WR; Zhang, KR; Zheng, JW | 1 |
Bai, HQ; Li, N; Li, Y; Wu, WR; Zhang, KR; Zheng, JW | 1 |
Allouche, S; Jauzac, P; Marie, N; Roussel, M | 1 |
Akil, H; Lee, KO; Traynor, JR; Woods, JH | 1 |
Fang, L; Kawase, M; Morimoto, Y; Ohmori, S; Saito, S | 1 |
Benyhe, S; Biyashev, D; Borsodi, A; Garadnay, S; Makleit, S; Marton, J | 1 |
Chaipatikul, V; Erickson-Herbrandson, LJ; Law, PY; Loh, HH | 1 |
Brink, CF; Erasmus, J | 1 |
Patel, K; Purohit, V; Yoburn, BC; Zhang, Q | 1 |
Eisinger, DA; Schulz, R; Wehmeyer, A | 1 |
Chen, C; Chong, PL; Huang, P; Liu-Chen, LY; Xu, W; Yoon, SI | 1 |
Chen, C; Chong, PL; Huang, P; Liu-Chen, LY; Unterwald, EM; Xu, W; Yoon, SI | 1 |
Binyaminy, B; Gafni, M; Sarne, Y; Shapira, M | 1 |
Ammer, H; Eisinger, DA | 1 |
Freye, E; Levy, JV | 1 |
Dixon, JP; Stein, BE | 1 |
148 other study(ies) available for etorphine and naloxone
Article | Year |
---|---|
O3-(2-carbomethoxyallyl) ethers of opioid ligands derived from oxymorphone, naltrexone, etorphine, diprenorphine, norbinaltorphimine, and naltrindole. Unexpected O3-dealkylation in the opioid radioligand displacement assay.
Topics: Alkylation; Animals; Brain; Diprenorphine; Drug Stability; Ethers; Etorphine; Guinea Pigs; Indoles; Methacrylates; Molecular Structure; Morphinans; Naltrexone; Narcotic Antagonists; Narcotics; Oxymorphone; Phenols; Radioligand Assay; Receptors, Opioid; Tritium | 1992 |
N-substituent modulation of opiate agonist/antagonist activity in resolved 3-methyl-3-(m-hydroxyphenyl)piperidines.
Topics: Animals; In Vitro Techniques; Mice; Molecular Conformation; Narcotic Antagonists; Narcotics; Phenols; Piperidines; Rats; Receptors, Opioid; Sodium; Stereoisomerism; Structure-Activity Relationship; X-Ray Diffraction | 1986 |
Different receptor sites mediate opioid agonism and antagonism.
Topics: Animals; Binding Sites; Kinetics; Naltrexone; Narcotic Antagonists; Narcotics; Receptors, Opioid; Structure-Activity Relationship | 1983 |
The specificity of binding of the narcotic agonist etorphine in synaptic membranes of rat brain in vivo.
Topics: Animals; Brain; Diprenorphine; Etorphine; Male; Morphinans; Naloxone; Rats; Receptors, Neurotransmitter; Stereoisomerism; Synaptic Membranes | 1975 |
Immobilon: curiously strong.
Topics: Accidents; Acepromazine; Animals; Drug Combinations; Etorphine; Humans; Methotrimeprazine; Morphinans; Naloxone; Neuroleptanalgesia; Occupational Diseases; Veterinary Medicine | 1977 |
The effects of local micro injections of opiates and enkephalins into the forebrain on the electrocorticogram of the rat.
Topics: Animals; Brain; Codeine; Electroencephalography; Endorphins; Enkephalins; Etorphine; Male; Morphinans; Morphine; Naloxone; Rats; Receptors, Dopamine; Thebaine | 1978 |
Different receptors for somatostatin and opioids in neuroblastoma X glioma hybrid cells.
Topics: Animals; Binding, Competitive; Cyclic AMP; Enkephalins; Etorphine; Glioma; Hybrid Cells; Naloxone; Neuroblastoma; Neurons; Prostaglandins E; Rats; Receptors, Cell Surface; Receptors, Opioid; Somatostatin | 1977 |
Binding of the endogenous nonpeptide morphine-like compound to opiate receptors.
Topics: Animals; Binding, Competitive; Brain Chemistry; Cattle; Cell Line; Cell Membrane; Enkephalins; Etorphine; Humans; In Vitro Techniques; Morphine; Naloxone; Narcotics; Radioimmunoassay; Receptors, Opioid | 1977 |
Characteristics and regional distributions of two distinct [3H]naloxone binding sites in the rat brain.
Topics: Animals; Binding Sites; Binding, Competitive; Brain; Cyclazocine; Diprenorphine; Etorphine; In Vitro Techniques; Male; Morphine; Nalorphine; Naloxone; Organ Specificity; Rats; Receptors, Opioid; Temperature | 1978 |
Specific-opiate-induced depression of transmitter release from dorsal root ganglion cells in culture.
Topics: Cells, Cultured; Depression, Chemical; Dose-Response Relationship, Drug; Etorphine; Ganglia, Spinal; Membrane Potentials; Morphinans; Naloxone; Nerve Endings; Spinal Cord; Synapses; Synaptic Transmission | 1978 |
Opiate binding to membrane preparations of neuroblastoma x glioma hybrid cells NG108-15: effects of ions and nucleotides.
Topics: Cell Membrane; Cells, Cultured; Enkephalins; Etorphine; Glioma; Guanylyl Imidodiphosphate; Hybrid Cells; Magnesium; Manganese; Naloxone; Neuroblastoma; Nucleotides; Receptors, Opioid; Sodium | 1978 |
Interaction of morphine, etorphine and enkephalins with dopamine-stimulated adenylate cyclase of monkey amygdala.
Topics: Adenylyl Cyclases; Amygdala; Animals; Dopamine; Dose-Response Relationship, Drug; Endorphins; Enkephalins; Etorphine; Freezing; Haplorhini; Macaca mulatta; Morphinans; Morphine; Naloxone; Receptors, Opioid; Stimulation, Chemical | 1979 |
Evidence that raphe-spinal neurons mediate opiate and midbrain stimulation-produced analgesias.
Topics: Action Potentials; Analgesia; Animals; Brain Stem; Cats; Electric Stimulation; Etorphine; Mesencephalon; Naloxone; Neurons; Nociceptors; Raphe Nuclei; Receptors, Opioid; Spinal Cord | 1978 |
Narcotic binding to membrane acidic lipids.
Topics: Animals; Cerebrosides; Chemical Phenomena; Chemistry; Etorphine; Levorphanol; Membrane Lipids; Models, Biological; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Receptors, Opioid; Stereoisomerism | 1979 |
Cerebellar opiate receptors in lagomorphs. Demonstration, characterization and regional distribution.
Topics: Animals; Brain Mapping; Cerebellar Cortex; Cerebellum; Cricetinae; Dextrorphan; Enkephalins; Etorphine; Female; Levorphanol; Male; Mice; Morphine; Naloxone; Rabbits; Rats; Receptors, Opioid; Species Specificity | 1979 |
Reduction of opiate binding to brainstem slices associated with the development of tolerance to morphine in rats.
Topics: Analgesics; Animals; Binding, Competitive; Brain Stem; Etorphine; Humans; In Vitro Techniques; Male; Morphine; Morphine Dependence; Naloxone; Rats; Receptors, Opioid; Sodium; Time Factors | 1979 |
A gas-liquid chromatographic method for the determination of naltrexone and beta-naltrexol in human urine.
Topics: Chromatography, Gas; Chromatography, High Pressure Liquid; Etorphine; Hot Temperature; Humans; Hydrogen-Ion Concentration; Naloxone; Naltrexone; Solvents | 1975 |
Opiate-dependent modulation of adenylate cyclase.
Topics: Adenosine; Adenylyl Cyclases; Cell Line; Cycloheximide; Enzyme Activation; Etorphine; Fluorides; Glioma; Guanylyl Imidodiphosphate; Hybrid Cells; Kinetics; Morphinans; Morphine; Naloxone; Neuroblastoma; Prostaglandins E | 1977 |
Inhibition of spinal cord interneurons by narcotic microinjection and focal electrical stimulation in the periaqueductal central gray matter.
Topics: Animals; Cerebral Aqueduct; Electric Stimulation; Etorphine; Evoked Potentials; Interneurons; Male; Mechanoreceptors; Morphine; Naloxone; Neural Inhibition; Neural Pathways; Nociceptors; Rats; Reflex; Spinal Cord; Tail | 1979 |
Evaluation of fentanyl citrate, etorphine hydrochloride, and naloxone hydrochloride in captive polar bears.
Topics: Anesthesia; Animals; Carnivora; Etorphine; Female; Fentanyl; Immobilization; Male; Morphinans; Naloxone; Ursidae | 1979 |
In vivo opiate binding unchanged in tolerant/dependent mice.
Topics: Animals; Binding, Competitive; Cerebellum; Drug Tolerance; Etorphine; Humans; Mice; Morphine; Morphine Dependence; Naloxone; Narcotics; Substance Withdrawal Syndrome; Time Factors | 1979 |
Inhibition by etorphine of the discharge of dorsal horn neurons: effects on the neuronal response to both high- and low-threshold sensory input in the decerebrate spinal cat.
Topics: Animals; Cats; Decerebrate State; Differential Threshold; Dose-Response Relationship, Drug; Etorphine; Evoked Potentials; Morphinans; Naloxone; Neurons; Sensation; Spinal Cord; Touch | 1978 |
Enhancement of a nociceptive reaction by opioid antagonists in mice.
Topics: Animals; Buprenorphine; Etorphine; Male; Mice; Morphine; Motor Activity; Naloxone; Narcotic Antagonists; Pain; Stereoisomerism | 1978 |
Clinical observations on the antagonism of immobilon by naloxone in dogs.
Topics: Anesthesia; Animals; Dogs; Drug Combinations; Etorphine; Methotrimeprazine; Morphinans; Naloxone; Pulse; Respiration | 1978 |
Comparison of the behavioral effects of beta-endorphin and enkephalin analogs.
Topics: Animals; Behavior, Animal; Endorphins; Enkephalins; Etorphine; Male; Mice; Morphine; Motor Activity; Naloxone; Oligopeptides; Peptides; Rats | 1977 |
Selective opiate depression of sensory-evoked synaptic networks in dorsal horn regions of spinal cord cultures.
Topics: Animals; Dextrorphan; Etorphine; Evoked Potentials; Levorphanol; Mice; Morphine; Naloxone; Organ Culture Techniques; Reaction Time; Spinal Cord; Synapses | 1977 |
Kinetics of opiate receptor inactivation by sulfhydryl reagents: evidence for conformational change in presence of sodium ions.
Topics: Alkylation; Animals; Binding Sites; Brain; Cyclopropanes; Ethylmaleimide; Etorphine; Kinetics; Naloxone; Narcotics; Protein Conformation; Rats; Receptors, Drug; Sodium Chloride; Subcellular Fractions; Sulfhydryl Reagents; Temperature | 1975 |
beta-Lipotropin as a prohormone for the morphinomimetic peptides endorphins and enkephalins.
Topics: Amino Acid Sequence; beta-Lipotropin; Binding, Competitive; Brain; Etorphine; Ileum; Morphine Derivatives; Naloxone; Nerve Tissue Proteins; Oligopeptides; Protein Precursors; Receptors, Drug; Structure-Activity Relationship | 1976 |
Tolerance and dependence evoked by an endogenous opiate peptide.
Topics: Adenylyl Cyclases; Cells, Cultured; Drug Tolerance; Enzyme Activation; Etorphine; Glioma; Humans; Hybrid Cells; Ligands; Naloxone; Neuroblastoma; Oligopeptides; Prostaglandins E; Substance-Related Disorders | 1976 |
A peptide-like substance from pituitary that acts like morphine. 2. Purification and properties.
Topics: Animals; Binding, Competitive; Biological Assay; Brain; Carboxypeptidases; Cattle; Chromatography, Ion Exchange; Chymotrypsin; Etorphine; Guinea Pigs; Ileum; Molecular Weight; Morphine; Morphine Derivatives; Naloxone; Peptides; Pituitary Gland; Receptors, Drug; Sodium; Swine; Trypsin | 1975 |
A peptide-like substance from pituitary that acts like morphine. I. Isolation.
Topics: Animals; Binding, Competitive; Biological Assay; Brain; Cattle; Etorphine; Ileum; Male; Morphine; Naloxone; Peptides; Pituitary Gland; Receptors, Drug; Sodium; Vas Deferens | 1975 |
Comparison of in vivo and in vitro parameters of opiate receptor binding in naive and tolerant dependent rodents.
Topics: Animals; Autoradiography; Brain; Cyclopropanes; Drug Tolerance; Etorphine; Humans; Levallorphan; Mice; Morphine; Naloxone; Opium; Pain; Rats; Receptors, Drug; Stereoisomerism; Structure-Activity Relationship; Substance Withdrawal Syndrome; Substance-Related Disorders | 1975 |
An appraisal of naloxone hydrochloride as a narcotic antagonist in the capture and release of wild herbivores.
Topics: Animals; Antelopes; Artiodactyla; Buffaloes; Elephants; Etorphine; Fentanyl; Male; Mammals; Naloxone; Perissodactyla; Swine | 1975 |
Protein kinase C activation increases the rate and magnitude of agonist-induced delta-opioid receptor down-regulation in NG108-15 cells.
Topics: Alkaloids; Cell Membrane; Cells, Cultured; Chloroquine; Down-Regulation; Enkephalin, Leucine-2-Alanine; Enzyme Activation; Etorphine; In Vitro Techniques; Naloxone; Narcotics; Neurons; Protein Kinase C; Receptors, Opioid, delta; Staurosporine; Tetradecanoylphorbol Acetate | 1992 |
Cloning of a delta opioid receptor by functional expression.
Topics: Amino Acid Sequence; Animals; Binding, Competitive; Blotting, Northern; Blotting, Southern; Cell Line; Cyclic AMP; Diprenorphine; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Etorphine; Gene Expression; Humans; Kinetics; Models, Structural; Molecular Sequence Data; Naloxone; Narcotics; Protein Structure, Secondary; Receptors, Opioid, delta; Sequence Homology, Amino Acid; Transfection; Tumor Cells, Cultured | 1992 |
Effects of iontophoretic etorphine and naloxone, and electroacupuncture on nociceptive responses from thalamic neurones in rabbits.
Topics: Animals; Electroacupuncture; Etorphine; Evoked Potentials; Iontophoresis; Naloxone; Neurons; Neurons, Afferent; Nociceptors; Rabbits; Synaptic Transmission; Thalamus | 1991 |
Paradoxical opiate specific paralytic effects of high doses of intracerebroventricular etorphine and fentanyl in rats.
Topics: Animals; Etorphine; Fentanyl; Injections, Intraventricular; Injections, Spinal; Male; Naloxone; Paralysis; Rats; Rats, Inbred Strains; Receptors, Opioid | 1991 |
[Effect of dihydroetorphine on contraction response of guinea pig ileum, mouse, and rabbit vas deferens induced by electric field stimulation in vitro].
Topics: Analgesics, Opioid; Animals; Etorphine; Guinea Pigs; Ileum; Male; Mice; Morphine; Muscle Contraction; Naloxone; Narcotics; Rabbits; Vas Deferens | 1991 |
Immobilization of gray wolves (Canis lupus) with sufentanil citrate.
Topics: Anesthetics; Animals; Arousal; Carnivora; Etorphine; Female; Fentanyl; Immobilization; Male; Naloxone; Sufentanil; Xylazine; Yohimbine | 1990 |
Effects of calcium-channel blockers (CCB) on mu and delta opioid receptors in rat brain membranes.
Topics: Animals; Brain; Calcium Channel Blockers; Calcium Channels; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Etorphine; In Vitro Techniques; Naloxone; Rats; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu | 1990 |
Electrophilic alpha-methylene-gamma-lactone and isothiocyanate opioid ligands related to etorphine.
Topics: Chemical Phenomena; Chemistry; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Etorphine; Isothiocyanates; Lactones; Ligands; Magnetic Resonance Spectroscopy; Molecular Structure; Morphinans; Naloxone; Receptors, Opioid; Receptors, Opioid, mu; Spectrophotometry, Infrared; Stereoisomerism; Thebaine; Thiocyanates | 1990 |
The effect of hyperthyroidism on opiate receptor binding and pain sensitivity.
Topics: Animals; Brain; Etorphine; Hyperthyroidism; Ligands; Male; Mice; Mice, Inbred Strains; Morphine; Naloxone; Pain; Receptors, Opioid; Thyroxine | 1990 |
Opioid binding properties of the purified kappa receptor from human placenta.
Topics: Benzomorphans; Binding, Competitive; Chromatography; Cyclazocine; Electrophoresis, Polyacrylamide Gel; Ethylketocyclazocine; Etorphine; Humans; Molecular Weight; Naloxone; Narcotics; Placenta; Radioligand Assay; Receptors, Opioid; Receptors, Opioid, kappa | 1989 |
Pharmacological study of an irreversible partial agonist of opiate receptors, A-alpha-CAO.
Topics: Analgesia; Animals; Etorphine; Female; Guinea Pigs; Ileum; In Vitro Techniques; Male; Mice; Morphine; Muscle Contraction; Muscle, Smooth; Naloxone; Rabbits; Rats; Rats, Inbred Strains; Receptors, Opioid; Thebaine; Vas Deferens | 1989 |
Subtraction autoradiography of opiate receptor subtypes in human brain.
Topics: Autoradiography; Binding Sites; Binding, Competitive; Brain; Cerebral Cortex; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Etorphine; Humans; Middle Aged; Naloxone; Receptors, Opioid; Subcellular Fractions | 1987 |
Expression and regulation of kappa opiate receptors in rat spinal cord-dorsal root ganglion cocultures.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Cells, Cultured; Etorphine; Ganglia, Spinal; Naloxone; Pyrrolidines; Rats; Receptors, Opioid; Receptors, Opioid, kappa; Spinal Cord; Transcription, Genetic | 1986 |
Tetraethylammonium ions and 4-aminopyridine prevent opioid inhibition of neurohypophysial oxytocin release.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Electric Stimulation; Etorphine; Female; Naloxone; Oxytocin; Pituitary Gland, Posterior; Rats; Rats, Inbred Strains; Tetraethylammonium Compounds | 1987 |
Enhancement of [3H]DAGO1 binding to rat brain by low concentrations of monovalent cations.
Topics: Animals; Batrachotoxins; Benzomorphans; Brain Chemistry; Cations, Monovalent; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Etorphine; Guanine Nucleotides; Guanylyl Imidodiphosphate; In Vitro Techniques; Male; Naloxone; Rats; Receptors, Opioid; Temperature | 1987 |
ADP-ribosylation with pertussis toxin modulates the GTP-sensitive opioid ligand binding in digitonin-soluble extracts of rat brain membranes.
Topics: Adenosine Diphosphate Ribose; Animals; Brain; Cell Membrane; Digitonin; Electrophoresis, Polyacrylamide Gel; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Etorphine; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Naloxone; Oligopeptides; Pertussis Toxin; Rats; Receptors, Opioid; Sodium; Solubility; Virulence Factors, Bordetella | 1988 |
Effect of etorphine on adrenergic neurotransmission in the rat and guinea pig heart.
Topics: Animals; Electric Stimulation; Etorphine; Guinea Pigs; Heart; In Vitro Techniques; Male; Morphinans; Myocardium; Naloxone; Rats; Rats, Inbred Strains; Sympathetic Nervous System; Synaptic Transmission | 1988 |
Na+ ions and Gpp(NH)p selectively inhibit agonist interactions at mu- and kappa-opioid receptor sites in rabbit and guinea-pig cerebellum membranes.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Opioid; Animals; Benzomorphans; Binding, Competitive; Cerebellum; Diprenorphine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Etorphine; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Guinea Pigs; Hydrogen-Ion Concentration; In Vitro Techniques; Naloxone; Pyrrolidines; Rabbits; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Sodium | 1985 |
Characterization of opioid receptor subtypes in solution.
Topics: Animals; Brain; Cations; Cell Membrane; Chemical Phenomena; Chemistry, Physical; Chromatography, Gel; Dihydromorphine; Dynorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Etorphine; Guanylyl Imidodiphosphate; Iodoacetamide; Kinetics; Magnesium; Naloxone; Rats; Receptors, Opioid; Sodium; Solutions | 1986 |
On the opioid receptor subtype inhibiting the evoked release of 3H-noradrenaline from guinea-pig atria in vitro.
Topics: Animals; Atropine; Benzomorphans; Binding, Competitive; Corticosterone; Cyclazocine; Desipramine; Dynorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Etorphine; Guinea Pigs; Heart Atria; In Vitro Techniques; Morphine; Myocardium; Naloxone; Norepinephrine; Peptide Fragments; Phentolamine; Receptors, Opioid; Receptors, Opioid, kappa; Synapses | 1986 |
Effects of opioid compounds on desensitization of the nicotinic response of isolated bovine adrenal chromaffin cells.
Topics: Adrenal Medulla; Animals; Calcium; Cattle; Cells, Cultured; Chromaffin System; Diprenorphine; Drug Tolerance; Dynorphins; Endorphins; Enkephalin, Methionine; Epinephrine; Etorphine; Morphine; Naloxone; Nicotine; Norepinephrine; Peptide Fragments; Potassium | 1987 |
Body temperature effects of opioids in rats: intracerebroventricular administration.
Topics: Animals; beta-Endorphin; Body Temperature; Cyclazocine; Dose-Response Relationship, Drug; Endorphins; Ethylketocyclazocine; Etorphine; Heroin; Injections, Intraventricular; Injections, Subcutaneous; Male; Morphine; Naloxone; Narcotics; Pentazocine; Phenazocine; Rats; Rats, Inbred Strains | 1986 |
[Influence of intraventricular injection of etorphine and naloxone on the vagus-pressor response in rats].
Topics: Animals; Blood Pressure; Electric Stimulation; Etorphine; Injections, Intraventricular; Male; Morphinans; Naloxone; Rats; Vagus Nerve | 1986 |
Inhibition of analgesia by C-terminal deletion analogs of human beta-endorphin.
Topics: Analgesics; Animals; beta-Endorphin; Endorphins; Etorphine; In Vitro Techniques; Mice; Naloxone; Peptide Fragments; Rats; Receptors, Opioid | 1985 |
Beta-endorphin-(1-27) is a naturally occurring antagonist to etorphine-induced analgesia.
Topics: Animals; beta-Endorphin; Binding, Competitive; Dose-Response Relationship, Drug; Endorphins; Etorphine; Male; Mice; Morphinans; Naloxone; Pain; Peptide Fragments; Receptors, Opioid | 1985 |
Effects of 5,5'-dithiobis-(2-nitrobenzoic acid) on opiate binding to both the membrane-bound receptor and the partially purified opiate receptor.
Topics: Animals; Butorphanol; Cell Membrane; Dihydromorphine; Diprenorphine; Dithionitrobenzoic Acid; Dithiothreitol; Etorphine; Morphine; Nalorphine; Naloxone; Naltrexone; Nitrobenzoates; Oxymorphone; Rats; Receptors, Opioid | 1985 |
Tritiated etorphine and naloxone binding to opioid receptors in caudate nucleus in schizophrenia.
Topics: Aged; Caudate Nucleus; Etorphine; Female; Humans; Male; Middle Aged; Morphinans; Naloxone; Receptors, Opioid; Schizophrenia; Tritium | 1985 |
The anticonvulsant effects of DADLE are primarily mediated by activation of delta opioid receptors: interactions between delta and mu receptor antagonists.
Topics: Animals; Anticonvulsants; Cerebral Ventricles; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Etorphine; Male; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Seizures | 1985 |
Multiple states of opioid receptors may modulate adenylate cyclase in intact neuroblastoma X glioma hybrid cells.
Topics: Adenylyl Cyclases; Animals; Cell Line; Cyclic AMP; Diprenorphine; Dose-Response Relationship, Drug; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Etorphine; Glioma; Hybrid Cells; Kinetics; Ligands; Morphine; Naloxone; Neuroblastoma; Neurons; Receptors, Opioid; Receptors, Opioid, delta | 1985 |
Opiate receptors are present in the rat testis. Identification and localization in Sertoli cells.
Topics: Androgen-Binding Protein; Animals; Etorphine; Kinetics; Male; Naloxone; Rats; Rats, Inbred Strains; Receptors, Opioid; Sertoli Cells; Temperature; Time Factors | 1985 |
Hyperalgesia mediated by peripheral opiate receptors in the rat.
Topics: Administration, Topical; Animals; Behavior, Animal; Capsaicin; Etorphine; Hyperalgesia; Hyperesthesia; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Morphine; Naloxone; Neurons, Afferent; Rats; Rats, Inbred Strains; Receptors, Opioid | 1985 |
A human neuroblastoma cell line expresses mu and delta opioid receptor sites.
Topics: Bone Neoplasms; Cell Line; Child, Preschool; Diprenorphine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Etorphine; Female; Guanylyl Imidodiphosphate; Humans; Kinetics; Naloxone; Neuroblastoma; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Sodium Chloride | 1986 |
Ethanol increases the expression of functional delta-opioid receptors in neuroblastoma x glioma NG108-15 hybrid cells.
Topics: Cell Line; Cyclic AMP; Cycloheximide; Dactinomycin; Diprenorphine; DNA; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethanol; Etorphine; Glioma; Hybridomas; Naloxone; Neuroblastoma; Phenylisopropyladenosine; Receptors, Opioid; Receptors, Opioid, delta; Sodium; Transcription, Genetic | 1986 |
Morphine-mimetic anti-paratypic antibodies: cross-reactive properties.
Topics: Animals; Antibodies, Monoclonal; Binding, Competitive; Chromatography, Affinity; Cross Reactions; Etorphine; Immunoglobulin Fab Fragments; Immunoglobulin Idiotypes; Mice; Morphine; Naloxone; Rabbits; Receptors, Opioid | 1986 |
Sodium regulation of agonist binding at opioid receptors. I. Effects of sodium replacement on binding at mu- and delta-type receptors in 7315c and NG108-15 cells and cell membranes.
Topics: Adenylyl Cyclase Inhibitors; Animals; Cell Line; Cell Membrane; Cyclazocine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Ethylketocyclazocine; Etorphine; Glioma; Guinea Pigs; Monensin; Naloxone; Neuroblastoma; Pituitary Neoplasms; Rats; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Sodium | 1986 |
Cold-restraint stress reduces [3H]etorphine binding to rat brain membranes: influence of acute and chronic morphine and naloxone.
Topics: Animals; Brain; Cell Membrane; Cold Temperature; Etorphine; Kinetics; Male; Morphinans; Morphine; Naloxone; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Opioid; Stress, Physiological | 1986 |
The adenylate cyclase rebound response to naloxone in the NG108-15 cells. Effects of etorphine and other opiates.
Topics: Adenylyl Cyclases; Alprostadil; Cell Line; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Etorphine; Glioma; Morphinans; Morphine; Naloxone; Neuroblastoma; Receptors, Opioid | 1986 |
Decrease in delta and mu opioid receptor binding capacity in rat brain after chronic etorphine treatment.
Topics: Animals; Brain; Cell Membrane; Etorphine; Kinetics; Morphinans; Morphine; Naloxone; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Tissue Distribution | 1987 |
Modulation of rat brain opioid receptors by cannabinoids.
Topics: Animals; Cannabinoids; Cyclazocine; Dihydromorphine; Dose-Response Relationship, Drug; Dronabinol; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Ethylketocyclazocine; Etorphine; Male; Naloxone; Rats; Rats, Inbred Strains; Receptors, Opioid; Spiperone | 1987 |
Opiate receptor subtypes in the rat hypothalamus and neurointermediate lobe.
Topics: Animals; Binding, Competitive; Cyclazocine; Ethylketocyclazocine; Etorphine; Female; Hypothalamus; Kinetics; Naloxone; Phencyclidine; Pituitary Gland; Rats; Rats, Inbred Strains; Receptors, Opioid; Temperature | 1987 |
Opiates stimulate food consumption in the land snail Helix aspersa.
Topics: Animals; Dose-Response Relationship, Drug; Etorphine; Feeding Behavior; Helix, Snails; Morphine; Naloxone | 1986 |
Chronic exposure to opiate agonists increases proenkephalin biosynthesis in NG108 cells.
Topics: Animals; Cell Line; Colforsin; Enkephalin, Methionine; Enkephalins; Etorphine; Genes; Glioma; Hybrid Cells; Morphinans; Morphine; Naloxone; Neuroblastoma; Protein Precursors; RNA, Messenger; Transcription, Genetic | 1988 |
[Effect of microinjection of etorphine into the dorsal hippocampus on the forelimb withdraw reaction induced by stimulating the splanchnic nerve in the conscious rabbit].
Topics: Animals; Electric Stimulation; Etorphine; Female; Forelimb; Hippocampus; Male; Microinjections; Morphinans; Naloxone; Nociceptors; Rabbits; Splanchnic Nerves | 1988 |
Cardiovascular effects of etorphine in rats.
Topics: Adrenalectomy; Animals; Atropine; Blood Pressure; Etorphine; Heart Rate; Hemodynamics; Male; Morphinans; Naloxone; Prazosin; Propranolol; Rats; Rats, Inbred Strains; Vagotomy | 1988 |
Opiates distinguish spinal excitation from inhibition evoked by noxious heat stimuli in the rat: relevance to theories of analgesia.
Topics: Analgesia; Animals; Etorphine; gamma-Aminobutyric Acid; Hot Temperature; Injections, Intravenous; Male; Morphine; Naloxone; Narcotics; Rats; Rats, Inbred Strains; Spinal Cord | 1988 |
Aging alterations in the modulation of central dopaminergic cilioinhibition by etorphine in the marine mussel, Mytilus edulis: decrease in the inhibition of presynaptic dopamine release.
Topics: Aging; Animals; Bivalvia; Cilia; Dopamine; Etorphine; Ganglia; Morphinans; Naloxone; Serotonin; Synapses | 1987 |
Etorphine inhibition of pancreatic exocrine secretion in rats: comparison with methadone.
Topics: Anesthesia; Animals; Deoxyglucose; Diprenorphine; Electric Stimulation; Etorphine; Male; Methadone; Morphinans; Naloxone; Pancreas; Rats; Rats, Inbred Strains; Time Factors; Vagus Nerve | 1986 |
The effect of tolerance on opiate dependence as measured by the adenylate cyclase rebound response to naloxone in the NG108-15 model system.
Topics: Adenylyl Cyclases; Animals; Drug Tolerance; Etorphine; Humans; Hybrid Cells; Morphine; Naloxone; Opioid-Related Disorders; Receptors, Opioid | 1984 |
Mechanisms of multiple cellular adaptation processes in clonal cell lines during chronic opiate treatment.
Topics: Adaptation, Physiological; Adenylyl Cyclases; Animals; Cell Line; Clone Cells; Cytosol; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Etorphine; Glioma; Guanylyl Imidodiphosphate; Lanthanum; Mice; Naloxone; Narcotics; Neuroblastoma; Rats; Receptors, Opioid; Sodium; Time Factors | 1984 |
In vivo characterization of four types of opioid binding sites in rat brain.
Topics: Analgesics, Opioid; Animals; Brain; Buprenorphine; Diprenorphine; Etorphine; Fentanyl; Male; Naloxone; Rats; Rats, Inbred Strains; Receptors, Opioid; Sufentanil; Tritium | 1983 |
Opiates stimulate low Km GTPase in brain.
Topics: Adenylyl Cyclase Inhibitors; Animals; Brain; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Etorphine; GTP Phosphohydrolases; Guanosine Triphosphate; Male; Naloxone; Phosphoric Monoester Hydrolases; Rats; Rats, Inbred Strains; Tissue Distribution | 1984 |
Dose-dependent effects of prolyl-leucyl-glycinamide on morphine-induced analgesia, tolerance and dependence.
Topics: Analgesia; Animals; Body Temperature; Body Weight; Brain Chemistry; Drug Tolerance; Etorphine; Humans; Kinetics; Male; Mice; Morphine; Morphine Dependence; MSH Release-Inhibiting Hormone; Naloxone; Reaction Time; Receptors, Opioid | 1984 |
Central and peripheral inhibition of gastrointestinal transit in rats: narcotics differ substantially by acting at either or both levels.
Topics: Analgesics, Opioid; Animals; Etorphine; Gastrointestinal Motility; Heroin; Injections, Intraperitoneal; Injections, Intraventricular; Male; Meperidine; Morphine; Naloxone; Rats | 1984 |
Mosaic distribution of opiate receptors, parafascicular projections and acetylcholinesterase in rat striatum.
Topics: Acetylcholinesterase; Animals; Axonal Transport; Caudate Nucleus; Corpus Striatum; Enkephalin, Leucine-2-Alanine; Enkephalins; Etorphine; Leucine; Naloxone; Proline; Rats; Receptors, Opioid | 1981 |
An etorphine-evoked vagal reflex in rats is inhibited by naloxone, N-methylnaloxone, and SMS 201-995.
Topics: Animals; Blood Pressure; Etorphine; Heart Rate; Hydromorphone; Male; Morphinans; Naloxone; Octreotide; Oxymorphone; Rats; Rats, Inbred Strains; Reflex; Respiration; Somatostatin; Vagus Nerve | 1983 |
Inquiry into endorphinergic feedback mechanisms during the development of opiate tolerance/dependence.
Topics: Animals; Brain; Dextrorphan; Drug Tolerance; Endorphins; Etorphine; Feedback; Humans; Levorphanol; Loperamide; Male; Naloxone; Opioid-Related Disorders; Pituitary Gland; Rats; Receptors, Opioid | 1980 |
Some aspects of opiate receptors.
Topics: Animals; Dendrites; Etorphine; Guinea Pigs; Humans; Ileum; Ligands; Male; Mice; Naloxone; Nerve Endings; Rats; Receptors, Neurotransmitter; Receptors, Opioid; Substance-Related Disorders; Vas Deferens | 1980 |
Control of guinea pig intestinal electrolyte secretion by a delta-opiate receptor.
Topics: Animals; Chlorides; Electric Conductivity; Endorphins; Etorphine; Female; Fentanyl; Guinea Pigs; Intestinal Mucosa; Membrane Potentials; Morphine; Muscle, Smooth; Naloxone; Receptors, Opioid | 1980 |
Opiate binding sites in the retina: properties and distribution.
Topics: Animals; Binding Sites; Bufo marinus; Cattle; Cell Membrane; Enkephalin, Methionine; Enkephalins; Etorphine; Fishes; Male; Naloxone; Rats; Receptors, Opioid; Retina | 1980 |
Conditioned increases in locomotor activity produced with morphine as an unconditioned stimulus, and the relation of conditioning to acute morphine effect and tolerance.
Topics: Animals; Conditioning, Classical; Dose-Response Relationship, Drug; Drug Tolerance; Etorphine; Male; Morphine; Motor Activity; Naloxone; Rats; Receptors, Opioid; Reinforcement, Psychology; Social Environment | 1981 |
Quaternary naltrexone: evidence for the central mediation of discriminative stimulus effects of narcotic agonists and antagonists.
Topics: Animals; Brain; Columbidae; Discrimination, Psychological; Etorphine; Macaca mulatta; Male; Morphine; Muscle Contraction; Muscle, Smooth; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Receptors, Opioid | 1981 |
Effect of age on sensitivity to pain and brain opiate receptors.
Topics: Aging; Animals; Brain; Etorphine; Hindlimb; Male; Naloxone; Nociceptors; Rats; Receptors, Opioid; Sensory Thresholds; Tail | 1981 |
Evidence for opiate receptor binding in rat small intestine.
Topics: Animals; Dextrorphan; Etorphine; In Vitro Techniques; Intestine, Small; Levorphanol; Male; Microsomes; Naloxone; Rats; Receptors, Opioid; Sodium | 1981 |
Comparison of the anticonvulsant effects of opioid peptides and etorphine in rats after icv administration.
Topics: Animals; Anticonvulsants; beta-Endorphin; Dose-Response Relationship, Drug; Endorphins; Enkephalin, Methionine; Enkephalins; Etorphine; Flurothyl; Male; Morphinans; Naloxone; Rats; Rats, Inbred Strains; Seizures; Structure-Activity Relationship | 1981 |
Naltrexone-induced opiate receptor supersensitivity.
Topics: Animals; Brain; Dihydromorphine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Etorphine; Female; Guanosine Triphosphate; Naloxone; Naltrexone; Rats; Rats, Inbred Strains; Receptors, Opioid | 1982 |
Etorphine binds to multiple opiate receptors of the caudate nucleus with equal affinity but with different kinetics.
Topics: Animals; Binding, Competitive; Caudate Nucleus; Diprenorphine; Edetic Acid; Etorphine; In Vitro Techniques; Kinetics; Membranes; Morphinans; Morphine; Naloxone; Receptors, Opioid; Sodium Chloride | 1982 |
Effects of opiate antagonists and putative mu- and kappa-agonists on milk intake in rat and squirrel monkey.
Topics: Animals; Buprenorphine; Cyclazocine; Diazepam; Diprenorphine; Drinking; Ethylketocyclazocine; Etorphine; Male; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Saimiri; Taste | 1982 |
Receptor binding, antagonist, and withdrawal precipitating properties of opiate antagonists.
Topics: Animals; Binding, Competitive; Brain; Cell Membrane; Etorphine; Humans; Ileum; Kinetics; Macaca mulatta; Male; Morphine Dependence; Muscle Contraction; Naloxone; Narcotic Antagonists; Rats; Rats, Inbred Strains; Receptors, Opioid; Structure-Activity Relationship; Substance Withdrawal Syndrome | 1983 |
A study of gastrointestinal opiate receptors: the role of the Mu receptor on gastric emptying: concise communication.
Topics: Adult; Aged; Depression, Chemical; Etorphine; Gastric Emptying; Gastrointestinal Motility; Humans; Middle Aged; Naloxone; Radionuclide Imaging; Receptors, Opioid; Receptors, Opioid, mu; Stomach | 1983 |
Functional opiate receptor in mouse vas deferens: evidence for a complex interaction.
Topics: Animals; Arylsulfatases; beta-Endorphin; Dose-Response Relationship, Drug; Drug Interactions; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Etorphine; Male; Mice; Mice, Inbred ICR; Morphine; Muscle Contraction; Naloxone; Receptors, Opioid; Sulfatases; Vas Deferens | 1983 |
Failure of opiates to increase the hydrolysis of GTP in neuroblastoma-glioma 108-15 cells.
Topics: Alprostadil; Animals; Cell Line; Cyclic AMP; Etorphine; Glioma; Guanine Nucleotides; Guanosine Triphosphate; Mice; Naloxone; Neuroblastoma; Prostaglandins E; Tritium | 1983 |
Characterization of solubilized opiate receptors from human placenta.
Topics: Binding, Competitive; Chemical Phenomena; Chemistry, Physical; Cyclazocine; Ethylketocyclazocine; Etorphine; Female; Humans; Naloxone; Placenta; Pregnancy; Receptors, Opioid; Solubility | 1983 |
Chronic naltrexone increases opiate binding in brain and produces supersensitivity to morphine in the locus coeruleus of the rat.
Topics: Animals; Brain; Etorphine; Locus Coeruleus; Male; Morphine; Naloxone; Naltrexone; Narcotics; Neurons; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu; Synaptic Transmission; Yohimbine | 1983 |
Effect of digitonin on the binding of opiate agonists and antagonists to membrane-bound and soluble opioid binding sites.
Topics: Animals; Brain; Bufo marinus; Digitonin; Diprenorphine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Etorphine; Male; Naloxone; Oxymorphone; Rats; Rats, Inbred Strains; Receptors, Opioid; Species Specificity | 1984 |
Opiate receptor binding-effect relationship: sufentanil and etorphine produce analgesia at the mu-site with low fractional receptor occupancy.
Topics: Animals; Brain; Diprenorphine; Drug Interactions; Etorphine; Fentanyl; Morphinans; Naloxone; Pain; Rats; Receptors, Opioid; Sufentanil | 1984 |
Discrimination of three types of opioid binding sites in rat brain in vivo.
Topics: Animals; Binding, Competitive; Brain; Diprenorphine; Etorphine; Fentanyl; Male; Naloxone; Rats; Receptors, Opioid; Sufentanil | 1984 |
The antinociceptive action of etorphine in the dorsal horn is due to a direct spinal action and not to activation of descending inhibition.
Topics: Analgesics; Animals; Cats; Decerebrate State; Etorphine; Female; Hot Temperature; Male; Microinjections; Morphinans; Naloxone; Neural Inhibition; Spinal Nerve Roots; Stereotaxic Techniques | 1983 |
Bremazocine induces antinociception, but prevents opioid-induced constipation and catatonia in rats and precipitates withdrawal in morphine-dependent rats.
Topics: Analgesics; Animals; Benzomorphans; Catatonia; Constipation; Dose-Response Relationship, Drug; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Etorphine; Gastrointestinal Motility; Humans; Male; Morphinans; Morphine; Naloxone; Rats; Substance Withdrawal Syndrome; Substance-Related Disorders | 1984 |
Alterations in high-affinity binding characteristics and levels of opioids in invertebrate ganglia during aging: evidence for an opioid compensatory mechanism.
Topics: Adenylyl Cyclases; Aging; Animals; Bivalvia; Dopamine; Endorphins; Enkephalin, Methionine; Etorphine; Ganglia; Insecta; Naloxone; Sex Factors | 1984 |
Light and ultrastructural characteristics of neuroblastoma glioma hybrid NG 108-15 cells.
Topics: Animals; Cell Line; Etorphine; Glioma; Hybrid Cells; Mice; Naloxone; Neuroblastoma; Rats | 1983 |
Effects of naloxone, diprenorphine, buprenorphine and etorphine on unpunished and punished food-reinforced responding in the squirrel monkey.
Topics: Animals; Buprenorphine; Diprenorphine; Dose-Response Relationship, Drug; Etorphine; Female; Male; Morphinans; Naloxone; Punishment; Reinforcement, Psychology; Saimiri | 1984 |
Enhancement of etorphine brain concentrations and changes in etorphine-naloxone pA2 values in morphine-pretreated mice.
Topics: Analgesics; Animals; Binding Sites; Brain; Etorphine; Male; Morphinans; Morphine; Naloxone; Rats | 1981 |
Enkephalins affect hippocampal membrane phosphorylation.
Topics: Animals; Cell Membrane; Endorphins; Enkephalins; Etorphine; Hippocampus; In Vitro Techniques; Male; Membranes; Mitochondria; Molecular Weight; Naloxone; Phosphorylation; Rats; Synaptosomes | 1980 |
Antinociceptive effect of dihydroetorphine in diabetic mice.
Topics: Analgesia; Analgesics, Opioid; Animals; Binding, Competitive; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Etorphine; Injections, Intraperitoneal; Injections, Intraventricular; Injections, Subcutaneous; Male; Mice; Mice, Inbred ICR; Naloxone; Naltrexone; Narcotic Antagonists; Pain Measurement; Receptors, Opioid, delta; Receptors, Opioid, mu | 1995 |
Physical dependence produced by dihydroetorphine in mice.
Topics: Analgesics; Animals; Etorphine; Injections, Intraventricular; Male; Mice; Mice, Inbred Strains; Morphine Dependence; Naloxone; Opioid-Related Disorders; Substance Withdrawal Syndrome | 1994 |
kappa-Opioid receptor-transfected cell lines: modulation of adenylyl cyclase activity following acute and chronic opioid treatments.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Animals; Benzeneacetamides; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Etorphine; GTP-Binding Proteins; Naloxone; Naltrexone; Opioid Peptides; Pertussis Toxin; Pyrrolidines; Receptors, Opioid, kappa; Virulence Factors, Bordetella | 1995 |
Different subtypes of opioid receptors have different affinities for G-proteins.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adenylyl Cyclases; Amino Acid Sequence; Animals; Binding, Competitive; Cerebellum; Colforsin; Diprenorphine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Etorphine; GTP-Binding Proteins; Guinea Pigs; Humans; Hybrid Cells; Molecular Sequence Data; Morphine; Naloxone; Neoplasm Proteins; Nerve Tissue Proteins; Neuroblastoma; Oligopeptides; Pyrrolidines; Rabbits; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Tumor Cells, Cultured | 1994 |
Antagonists at excitatory opioid receptors on sensory neurons in culture increase potency and specificity of opiate analgesics and attenuate development of tolerance/dependence.
Topics: Analgesics; Animals; Cells, Cultured; Diprenorphine; Drug Tolerance; Electrophysiology; Enkephalin, Leucine-2-Alanine; Etorphine; Ganglia, Spinal; Mice; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Neurons, Afferent; Opioid-Related Disorders | 1994 |
Antinociceptive effect of dihydroetorphine and its tolerance/dependence liability in mice.
Topics: Analgesics; Animals; Body Weight; Drug Tolerance; Etorphine; Male; Mice; Mice, Inbred Strains; Morphine; Motor Activity; Naloxone; Naltrexone; Narcotic Antagonists; Pain Measurement; Substance-Related Disorders | 1993 |
Modification of opioid receptors and uncoupling of receptors from G proteins as possible mechanisms underlying suppression of opioid binding by cholecystokinin octapeptide.
Topics: Animals; Binding Sites; Brain; Dose-Response Relationship, Drug; Etorphine; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Naloxone; Rats; Rats, Wistar; Receptors, Opioid; Sincalide | 1993 |
Opioid antagonist-induced receptor upregulation: effects of concurrent agonist administration.
Topics: Animals; Brain; Drug Combinations; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Etorphine; Fentanyl; Male; Mice; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid, mu; Up-Regulation | 1994 |
Opioid receptor regulation in mice.
Topics: Analgesics; Animals; Brain; Etorphine; Fentanyl; Male; Mice; Morphine; Naloxone; Narcotics; Receptors, Opioid, mu | 1993 |
Studies on mu and delta opioid receptor selectivity utilizing chimeric and site-mutagenized receptors.
Topics: Amino Acid Sequence; Analgesics; Base Sequence; Benzomorphans; Binding, Competitive; Cell Line; Cell Membrane; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Etorphine; GTP-Binding Proteins; Humans; Kidney; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Naloxone; Oligodeoxyribonucleotides; Polymerase Chain Reaction; Protein Structure, Secondary; Receptors, Opioid, delta; Receptors, Opioid, mu; Recombinant Fusion Proteins; Substrate Specificity; Transfection | 1995 |
Central opiate modulation of peripheral IL-6 in rats.
Topics: Animals; beta-Endorphin; Etorphine; Injections, Intraperitoneal; Injections, Intraventricular; Interleukin-1; Interleukin-6; Male; Morphine; Naloxone; Narcotics; Rats; Rats, Sprague-Dawley | 1996 |
Lack of effect of gamma-hydroxybutyrate on mu, delta and kappa opioid receptor binding.
Topics: Adjuvants, Anesthesia; Analgesics; Animals; Diprenorphine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Etorphine; Glioma; Guinea Pigs; Naloxone; Narcotic Antagonists; Narcotics; Neuroblastoma; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Sodium Oxybate; Tritium; Tumor Cells, Cultured | 1996 |
Chronic morphine-treated sensory ganglion neurons remain supersensitive to the excitatory effects of naloxone for months after return to normal culture medium: an in vitro model of 'protracted opioid dependence'.
Topics: Animals; Culture Media; Etorphine; Ganglia, Spinal; Mice; Mice, Inbred Strains; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Neurons; Reference Values; Substance-Related Disorders; Time Factors | 1995 |
Studies on the abstinence-like overshoot following reversal of the potent 19-isoamyl derivative of etorphine with naloxone. A comparison with the opioids fentanyl and alfentanil.
Topics: Alfentanil; Analgesics, Opioid; Animals; Blood Gas Analysis; Blood Pressure; Dogs; Dose-Response Relationship, Drug; Etorphine; Fentanyl; Heart Rate; Naloxone; Narcotic Antagonists; Receptors, Opioid, mu; Substance Withdrawal Syndrome | 1997 |
Ultrastructural changes in rat locus coeruleus induced by chronic opioids.
Topics: Analgesics; Animals; Endoplasmic Reticulum, Rough; Etorphine; Locus Coeruleus; Male; Morphine; Myelin Sheath; Naloxone; Narcotic Antagonists; Narcotics; Neurons; Polyribosomes; Rats; Rats, Wistar; Synaptic Vesicles | 1997 |
[Care of acute respiratory insufficiency due to etorphine intoxication treated by naloxone].
Topics: Acute Disease; Analgesics, Opioid; Etorphine; Humans; Naloxone; Narcotic Antagonists; Respiratory Insufficiency | 1996 |
Involvement of mu-opioid receptors and alpha-adrenoceptors in the immunomodulatory effects of dihydroetorphine.
Topics: Adjuvants, Immunologic; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Analgesics, Opioid; Animals; Cell Division; Etorphine; Female; Immunosuppressive Agents; Interleukin-2; Lymphocytes; Mice; Mice, Inbred BALB C; Naloxone; Narcotic Antagonists; Phentolamine; Propranolol; Receptors, Adrenergic, alpha; Receptors, Opioid, mu | 1998 |
Immunosuppressive effects of dihydroetorphine, a potent narcotic analgesic, in dihydroetorphine-dependent mice.
Topics: Analgesics, Opioid; Animals; Antibody-Producing Cells; Body Weight; Cell Division; Dose-Response Relationship, Drug; Etorphine; Female; Hypersensitivity, Delayed; Immunosuppressive Agents; Lymphocyte Count; Lymphocyte Subsets; Lymphocytes; Lymphokines; Mice; Mice, Inbred C57BL; Naloxone; Opioid-Related Disorders; Organ Size; Spleen; Substance Withdrawal Syndrome; Thymus Gland | 1999 |
Differential desensitization of human delta-opioid receptors by peptide and alkaloid agonists.
Topics: Adenylyl Cyclase Inhibitors; Alkaloids; Analgesics; Analgesics, Opioid; Cyclic AMP; Drug Interactions; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Etorphine; Humans; Naloxone; Neuroblastoma; Oligopeptides; Peptides; Receptors, Opioid, delta; Tumor Cells, Cultured | 1999 |
Differential binding properties of oripavines at cloned mu- and delta-opioid receptors.
Topics: Analgesics, Opioid; Animals; Benzamides; Binding, Competitive; Buprenorphine; Cloning, Molecular; Diprenorphine; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Etorphine; Fentanyl; Guanosine 5'-O-(3-Thiotriphosphate); Morphine; Naloxone; Piperazines; Radioligand Assay; Rats; Receptors, Opioid, delta; Receptors, Opioid, mu; Sulfur Radioisotopes; Thebaine; Tritium; Tumor Cells, Cultured | 1999 |
Tolerance to analgesia and dependence liability by topical application of dihydroetorphine to hairless rats.
Topics: Administration, Cutaneous; Analgesics, Opioid; Animals; Conditioning, Psychological; Dose-Response Relationship, Drug; Drug Tolerance; Etorphine; Formaldehyde; Inflammation; Infusions, Intravenous; Injections, Subcutaneous; Male; Morphine; Naloxone; Narcotic Antagonists; Rats; Rats, Nude; Substance-Related Disorders; Time Factors; Weight Loss | 2001 |
Biochemical characterisation of newly developed beta-etorphine and beta-dihydroetorphine derivatives.
Topics: Animals; Binding, Competitive; Brain; Cell Membrane; Etorphine; Guanosine 5'-O-(3-Thiotriphosphate); Naloxone; Radioligand Assay; Rats; Rats, Wistar; Structure-Activity Relationship; Sulfur Radioisotopes; Tritium | 2002 |
Rescuing the traffic-deficient mutants of rat mu-opioid receptors with hydrophobic ligands.
Topics: Animals; Cells, Cultured; Cyclic AMP; Etorphine; Humans; Ligands; Membrane Proteins; Mutation; Naloxone; Narcotics; Rats; Receptors, Opioid, mu; Transfection | 2003 |
Etorphine poisoning.
Topics: Adult; Analgesics, Opioid; Etorphine; Humans; Injections; Male; Naloxone; Narcotic Antagonists; Poisoning; Respiration, Artificial | 2003 |
Opioid agonist and antagonist treatment differentially regulates immunoreactive mu-opioid receptors and dynamin-2 in vivo.
Topics: Analgesics, Opioid; Animals; Binding, Competitive; Blotting, Western; Dynamin II; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Etorphine; Male; Mice; Morphine; Naloxone; Narcotic Antagonists; Radioligand Assay; Receptors, Opioid, mu; Spinal Cord | 2004 |
Opioid control of MAP kinase cascade.
Topics: Cell Line; Dipeptides; Epidermal Growth Factor; ErbB Receptors; Etorphine; Humans; Ligands; MAP Kinase Signaling System; Morphine; Naloxone; Narcotics; Oligopeptides; Phenylalanine; Phosphorylation; Receptors, sigma; Thiophenes; Transfection | 2004 |
Cholesterol reduction by methyl-beta-cyclodextrin attenuates the delta opioid receptor-mediated signaling in neuronal cells but enhances it in non-neuronal cells.
Topics: Animals; Anticholesteremic Agents; beta-Cyclodextrins; Brain; Caveolin 1; Cell Line, Tumor; CHO Cells; Cholesterol; Cricetinae; Cricetulus; Diprenorphine; Enkephalin, D-Penicillamine (2,5)-; Etorphine; G(M1) Ganglioside; Hybrid Cells; Levorphanol; Membrane Microdomains; Membrane Proteins; Naloxone; Neurons; Oligopeptides; Receptors, Opioid, delta; Signal Transduction | 2007 |
Agonist treatment did not affect association of mu opioid receptors with lipid rafts and cholesterol reduction had opposite effects on the receptor-mediated signaling in rat brain and CHO cells.
Topics: Animals; Binding, Competitive; Brain; Caveolin 1; CHO Cells; Cholesterol; Cricetinae; Cricetulus; Diprenorphine; Dose-Response Relationship, Drug; Etorphine; Male; Membrane Microdomains; Morphine; Naloxone; Narcotic Antagonists; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Signal Transduction; Transfection | 2007 |
Agonist-specific down regulation of mu-opioid receptors: Different cellular pathways are activated by different opioid agonists.
Topics: Aminopeptidases; Analgesics, Opioid; Cell Adhesion; Clathrin; DNA, Complementary; Dose-Response Relationship, Drug; Down-Regulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Etorphine; Humans; Lysosomes; Membranes; Naloxone; Narcotic Antagonists; Phosphotransferases; Protease Inhibitors; Receptors, Opioid, mu; Serine Endopeptidases; Signal Transduction | 2008 |
delta-Opioid receptors stimulate ERK1/2 activity in NG108-15 hybrid cells by integrin-mediated transactivation of TrkA receptors.
Topics: Cell Adhesion; Enkephalin, Leucine-2-Alanine; Etorphine; Glioma; Humans; Hybrid Cells; Integrins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Naloxone; Neuroblastoma; Neurons; Oligopeptides; Protein Kinase Inhibitors; Receptor, trkA; Receptors, Opioid, delta; Transcriptional Activation; Tyrphostins | 2008 |
No hyperalgesia following opioid withdrawal after the oripavine derivative etorphine compared to remifentanil and sufentanil.
Topics: Afferent Pathways; Analgesics, Opioid; Animals; Blood Pressure; Bradycardia; Dogs; Dose-Response Relationship, Drug; Etorphine; Evoked Potentials, Somatosensory; Heart Rate; Hyperalgesia; Hypotension; Naloxone; Narcotic Antagonists; Piperidines; Remifentanil; Substance Withdrawal Syndrome; Sufentanil | 2010 |
Superior colliculus cells respond to noxious stimuli.
Topics: Action Potentials; Animals; Cricetinae; Etorphine; Hypnotics and Sedatives; Mesocricetus; Naloxone; Narcotic Antagonists; Neural Pathways; Nociceptors; Pain; Photic Stimulation; Physical Stimulation; Superior Colliculi; Time Factors | 1978 |