etorphine has been researched along with enkephalin, leucine-2-alanine in 61 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 45 (73.77) | 18.7374 |
1990's | 13 (21.31) | 18.2507 |
2000's | 3 (4.92) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Camerman, A; Camerman, N; Cheng, A; DeGraw, JI; Lawson, JA; Loew, G; Polgar, W; Toll, L; Uyeno, E | 1 |
Becketts, K; Bertha, CM; Davis, P; Ellis, M; Flippen-Anderson, JL; Porreca, F; Rice, KC; Rothman, RB; Xu, H | 1 |
Bidlack, JM; Gucker, S | 1 |
Elde, R; Lane, CM; Lee, NM; Loh, HH | 1 |
Borea, PA; Ongini, E; Trampus, M; Varani, K | 1 |
Chang, LR; Loh, HH; Tao, PL; Tsai, CL | 1 |
Katki, AG; Schwarz, S | 1 |
Biswas, R; Maneckjee, R; Vonderhaar, BK | 1 |
Cruciani, RA; Munson, PJ; Pesce, GO; Rodbard, D | 1 |
Cross, AJ; Hille, C; Slater, P | 1 |
Bolger, GT; Marcus, KA; Skolnick, P; Thibou, R; Weissman, BA | 1 |
Law, PY; Loh, HH; Louie, AK; Zhan, JN | 1 |
Barnard, EA; Demoliou-Mason, CD; Wong, YH | 1 |
Su, TP | 1 |
Barnard, EA; Demoliou-Mason, CD | 3 |
Buder, M; Fuder, H; Riers, HD; Rothacher, G | 1 |
Cruciani, RA; Gainer, H; Lang, MA; Pesce, GO; Rodbard, D; Russell, JT | 1 |
Archer, S; Maneckjee, R; Michael, J; Osei-Gyimah, P; Zukin, RS | 1 |
Bunn, SJ; Hanley, MR; Wilkin, GP | 1 |
Holaday, JW; Robles, L; Tortella, FC | 1 |
Garzón, J; Herz, A; Schulz, R | 2 |
Costa, T; Gramsch, C; Herz, A; Wüster, M | 1 |
Boudouresque, F; Bourhim, N; Cantau, P; Castanas, E; Giraud, P; Oliver, C | 1 |
Richards, ML; Sadée, W; Yu, VC | 1 |
Charness, ME; Diamond, I; Querimit, LA | 1 |
Klein, C; Levy, R; Simantov, R | 1 |
Coscia, CJ; Devane, WA; Howlett, AC; Spain, JW | 1 |
Brown, SR; Cote, TE; Cox, BM; Puttfarcken, P; Werling, LL | 1 |
Brown, SR; Cox, BM; Puttfarcken, P; Werling, LL | 1 |
Greenspan, DL; Musacchio, JM | 1 |
Sadée, W; Yu, VC | 1 |
Gainer, H; Lang, MA; Pesce, G; Rodbard, D; Russell, JT | 1 |
Chi, ZQ; Jin, WQ; Wu, SW | 1 |
Bourhim, N; Cantau, P; Castanas, E; Giraud, P; Oliver, C | 1 |
Griffin, MT; Law, PY; Loh, HH | 1 |
Franklin, PH; Hoss, W | 1 |
Herkenham, M; Pert, CB | 1 |
Duka, T; Herz, A; Schubert, P; Stoiber, R; Wüster, M | 1 |
Fitz-Syage, ML; Gardner, EL; Gintzler, AR; Sugarman, JR; Zukin, RS; Zukin, SR | 1 |
Guidotti, A; Saiani, L | 1 |
Attali, B; Audigier, Y; Cros, J; Gouardères, C; Mazarguil, H | 1 |
Kouakou, Y; Meunier, JC; Moisand, C; Puget, A | 1 |
Garzón, J; Lee, NM; Sánchez-Blázquez, P | 1 |
Rothman, R; Westfall, TC | 1 |
Cowan, A; Holaday, JW; Robles, LE; Tortella, FC | 1 |
Bradbury, WM; Cooper, JR; Glasel, JA; Reese, JH; Venn, RF | 1 |
Gioannini, TL; Hiller, JM; Itzhak, Y; Simon, EJ | 1 |
Govoni, S; Lucchi, L; Rius, RA; Trabucchi, M; Uzumaki, H | 1 |
Barg, J; Lenoir, D; Simantov, R | 1 |
Gambino, MC; Petrillo, P; Tavani, A | 1 |
Crain, SM; Shen, KF | 1 |
Evans, CJ; Keith, DE; Von Zastrow, M | 1 |
Bakogeorgou, E; Castanas, E; Hatzoglou, A | 1 |
Blake, AD; Bot, G; Li, S; Reisine, T | 1 |
Brine, GA; Carroll, FI; Chen, C; Lai, J; Liu-Chen, LY; Lu, YF; Partilla, JS; Porreca, F; Rice, KC; Rothman, RB; Sadee, W; Xu, H | 1 |
Benaderet, TS; Bishop-Mathis, K; Dersch, CM; Partilla, JS; Prisinzano, TE; Rothman, RB; Simpson, DS; Wang, X; Xu, H | 1 |
Ammer, H; Eisinger, DA | 2 |
61 other study(ies) available for etorphine and enkephalin, leucine-2-alanine
Article | Year |
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N-substituent modulation of opiate agonist/antagonist activity in resolved 3-methyl-3-(m-hydroxyphenyl)piperidines.
Topics: Animals; In Vitro Techniques; Mice; Molecular Conformation; Narcotic Antagonists; Narcotics; Phenols; Piperidines; Rats; Receptors, Opioid; Sodium; Stereoisomerism; Structure-Activity Relationship; X-Ray Diffraction | 1986 |
Probes for narcotic receptor-mediated phenomena. 21. Novel derivatives of 3-(1,2,3,4,5,11-hexahydro-3-methyl-2,6-methano-6H-azocino[4,5-b]indol- 6-yl)-phenols with improved delta opioid receptor selectivity.
Topics: Analgesics; Animals; Crystallography, X-Ray; Guinea Pigs; Ileum; In Vitro Techniques; Male; Mice; Mice, Inbred ICR; Molecular Probes; Phenols; Radioligand Assay; Receptors, Opioid, delta; Stereoisomerism; Vas Deferens | 1996 |
Protein kinase C activation increases the rate and magnitude of agonist-induced delta-opioid receptor down-regulation in NG108-15 cells.
Topics: Alkaloids; Cell Membrane; Cells, Cultured; Chloroquine; Down-Regulation; Enkephalin, Leucine-2-Alanine; Enzyme Activation; Etorphine; In Vitro Techniques; Naloxone; Narcotics; Neurons; Protein Kinase C; Receptors, Opioid, delta; Staurosporine; Tetradecanoylphorbol Acetate | 1992 |
Regulation of an opioid-binding protein in NG108-15 cells parallels regulation of delta-opioid receptors.
Topics: Amino Acid Sequence; Animals; Carrier Proteins; Cell Adhesion Molecules; Cell Compartmentation; Cell Membrane; Cells, Cultured; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; Etorphine; Fluorescent Antibody Technique; GPI-Linked Proteins; In Vitro Techniques; Membrane Glycoproteins; Molecular Sequence Data; Nerve Tissue Proteins; Neurons; Peptides; Rats; Receptors, Opioid, delta | 1992 |
The neutral endopeptidase-24.11 inhibitor SCH 34826 does not change opioid binding but reduces D1 dopamine receptors in rat brain.
Topics: Analgesics; Animals; Brain Chemistry; Dioxolanes; Dipeptides; Dopamine Antagonists; Enkephalin, Leucine-2-Alanine; Etorphine; Kinetics; Male; Morphine; Neprilysin; Rats; Rats, Inbred Strains; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Receptors, sigma | 1991 |
Chronic effect of [D-Pen2,D-Pen5]enkephalin on rat brain opioid receptors.
Topics: Analgesics; Animals; Brain Chemistry; Drug Tolerance; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; Etorphine; In Vitro Techniques; Injections, Intraventricular; Male; Rats; Rats, Inbred Strains; Reaction Time; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu | 1991 |
Effects of calcium-channel blockers (CCB) on mu and delta opioid receptors in rat brain membranes.
Topics: Animals; Brain; Calcium Channel Blockers; Calcium Channels; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Etorphine; In Vitro Techniques; Naloxone; Rats; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu | 1990 |
Binding of opioids to human MCF-7 breast cancer cells and their effects on growth.
Topics: Breast Neoplasms; Cell Division; Cell Line; Cell Membrane; Cyclazocine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Estradiol; Etorphine; Female; Humans; Kinetics; Morphinans; Morphine; Receptors, Opioid; Tumor Cells, Cultured | 1990 |
Computer modeling of subtypes of kappa opioid receptors in adrenal medulla.
Topics: Adrenal Medulla; Animals; Binding, Competitive; Cattle; Computer Simulation; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Etorphine; In Vitro Techniques; Kinetics; Models, Biological; Narcotics; Receptors, Opioid; Receptors, Opioid, kappa | 1990 |
Subtraction autoradiography of opiate receptor subtypes in human brain.
Topics: Autoradiography; Binding Sites; Binding, Competitive; Brain; Cerebral Cortex; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Etorphine; Humans; Middle Aged; Naloxone; Receptors, Opioid; Subcellular Fractions | 1987 |
Enhancement of [3H]DAGO1 binding to rat brain by low concentrations of monovalent cations.
Topics: Animals; Batrachotoxins; Benzomorphans; Brain Chemistry; Cations, Monovalent; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Etorphine; Guanine Nucleotides; Guanylyl Imidodiphosphate; In Vitro Techniques; Male; Naloxone; Rats; Receptors, Opioid; Temperature | 1987 |
Modification of opioid receptor activity by acid phosphatase in neuroblastoma x glioma NG108-15 hybrid cells.
Topics: Acid Phosphatase; Animals; Chromatography, High Pressure Liquid; Cyclic AMP; Diprenorphine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Etorphine; Glioma; Guanfacine; Guanidines; Hybrid Cells; Neuroblastoma; Phenylacetates; Receptors, Opioid | 1988 |
ADP-ribosylation with pertussis toxin modulates the GTP-sensitive opioid ligand binding in digitonin-soluble extracts of rat brain membranes.
Topics: Adenosine Diphosphate Ribose; Animals; Brain; Cell Membrane; Digitonin; Electrophoresis, Polyacrylamide Gel; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Etorphine; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Naloxone; Oligopeptides; Pertussis Toxin; Rats; Receptors, Opioid; Sodium; Solubility; Virulence Factors, Bordetella | 1988 |
Further demonstration of kappa opioid binding sites in the brain: evidence for heterogeneity.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Benzodiazepines; Binding Sites; Brain; Cyclazocine; Dynorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Etorphine; Guinea Pigs; Levallorphan; Peptide Fragments; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa; Stereoisomerism | 1985 |
Characterization of opioid receptor subtypes in solution.
Topics: Animals; Brain; Cations; Cell Membrane; Chemical Phenomena; Chemistry, Physical; Chromatography, Gel; Dihydromorphine; Dynorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Etorphine; Guanylyl Imidodiphosphate; Iodoacetamide; Kinetics; Magnesium; Naloxone; Rats; Receptors, Opioid; Sodium; Solutions | 1986 |
On the opioid receptor subtype inhibiting the evoked release of 3H-noradrenaline from guinea-pig atria in vitro.
Topics: Animals; Atropine; Benzomorphans; Binding, Competitive; Corticosterone; Cyclazocine; Desipramine; Dynorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Etorphine; Guinea Pigs; Heart Atria; In Vitro Techniques; Morphine; Myocardium; Naloxone; Norepinephrine; Peptide Fragments; Phentolamine; Receptors, Opioid; Receptors, Opioid, kappa; Synapses | 1986 |
Opioid receptors of bovine posterior pituitary neurosecretosomes are exclusively kappa.
Topics: Analgesics, Opioid; Animals; Cattle; Cyclazocine; Cytoplasmic Granules; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Etorphine; Kinetics; Morphinans; Pituitary Gland, Posterior; Receptors, Opioid; Receptors, Opioid, kappa | 1986 |
Purification and characterization of the mu opiate receptor from rat brain using affinity chromatography.
Topics: Animals; Brain Chemistry; Cholic Acids; Chromatography, Affinity; Dihydromorphine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Etorphine; Kinetics; Male; Molecular Weight; Protease Inhibitors; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu | 1985 |
Evidence for a kappa-opioid receptor on pituitary astrocytes: an autoradiographic study.
Topics: Animals; Astrocytes; Autoradiography; Binding Sites; Binding, Competitive; Cyclazocine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Ethylketocyclazocine; Etorphine; Pituitary Gland; Rats; Receptors, Opioid; Receptors, Opioid, kappa | 1985 |
The anticonvulsant effects of DADLE are primarily mediated by activation of delta opioid receptors: interactions between delta and mu receptor antagonists.
Topics: Animals; Anticonvulsants; Cerebral Ventricles; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Etorphine; Male; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Seizures | 1985 |
Evidence for the epsilon-type of opioid receptor in the rat vas deferens.
Topics: Animals; Binding, Competitive; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Drug Synergism; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Etorphine; Fentanyl; Male; Rats; Rats, Inbred Strains; Receptors, Opioid; Vas Deferens | 1985 |
Multiple states of opioid receptors may modulate adenylate cyclase in intact neuroblastoma X glioma hybrid cells.
Topics: Adenylyl Cyclases; Animals; Cell Line; Cyclic AMP; Diprenorphine; Dose-Response Relationship, Drug; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Etorphine; Glioma; Hybrid Cells; Kinetics; Ligands; Morphine; Naloxone; Neuroblastoma; Neurons; Receptors, Opioid; Receptors, Opioid, delta | 1985 |
Interaction of opiates with opioid binding sites in the bovine adrenal medulla: II. Interaction with kappa sites.
Topics: Adrenal Medulla; Animals; Benzomorphans; Binding Sites; Calcium; Cattle; Cyclazocine; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Ethylketocyclazocine; Ethylmaleimide; Etorphine; Guinea Pigs; Kinetics; Lithium; Manganese; Narcotics; Oligopeptides; Phospholipases A; Potassium; Receptors, Opioid; Receptors, Opioid, kappa; Sodium; Stereoisomerism | 1985 |
A human neuroblastoma cell line expresses mu and delta opioid receptor sites.
Topics: Bone Neoplasms; Cell Line; Child, Preschool; Diprenorphine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Etorphine; Female; Guanylyl Imidodiphosphate; Humans; Kinetics; Naloxone; Neuroblastoma; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Sodium Chloride | 1986 |
Ethanol increases the expression of functional delta-opioid receptors in neuroblastoma x glioma NG108-15 hybrid cells.
Topics: Cell Line; Cyclic AMP; Cycloheximide; Dactinomycin; Diprenorphine; DNA; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethanol; Etorphine; Glioma; Hybridomas; Naloxone; Neuroblastoma; Phenylisopropyladenosine; Receptors, Opioid; Receptors, Opioid, delta; Sodium; Transcription, Genetic | 1986 |
Distinct subtypes of the opioid receptor with allosteric interactions in brain membranes.
Topics: Allosteric Site; Animals; Brain; Cations; Cell Membrane; Dihydromorphine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Etorphine; Guanylyl Imidodiphosphate; Kinetics; Magnesium; Male; Rats; Rats, Inbred Strains; Receptors, Opioid; Sodium | 1986 |
Subcellular compartmentation of opioid receptors: modulation by enkephalin and alkaloids.
Topics: Animals; Cell Line; Cell Membrane; Centrifugation, Density Gradient; Chloroquine; Diprenorphine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Etorphine; Glioma; Golgi Apparatus; Kinetics; Lysosomes; Microsomes; Neuroblastoma; Receptors, Opioid | 1986 |
An assessment of the role of opioid receptors in the response to cannabimimetic drugs.
Topics: Adenylyl Cyclase Inhibitors; Animals; Cannabinoids; Cell Line; Dronabinol; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Etorphine; Morphine; Naltrexone; Neuroblastoma; Neurons; Receptors, Opioid; Receptors, Opioid, delta | 1986 |
Sodium regulation of agonist binding at opioid receptors. I. Effects of sodium replacement on binding at mu- and delta-type receptors in 7315c and NG108-15 cells and cell membranes.
Topics: Adenylyl Cyclase Inhibitors; Animals; Cell Line; Cell Membrane; Cyclazocine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Ethylketocyclazocine; Etorphine; Glioma; Guinea Pigs; Monensin; Naloxone; Neuroblastoma; Pituitary Neoplasms; Rats; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Sodium | 1986 |
Sodium regulation of agonist binding at opioid receptors. II. Effects of sodium replacement on opioid binding in guinea pig cortical membranes.
Topics: Animals; Cell Membrane; Cerebral Cortex; Cyclazocine; Diprenorphine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Ethylketocyclazocine; Etorphine; Guinea Pigs; Male; Oligopeptides; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Sodium | 1986 |
The adenylate cyclase rebound response to naloxone in the NG108-15 cells. Effects of etorphine and other opiates.
Topics: Adenylyl Cyclases; Alprostadil; Cell Line; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Etorphine; Glioma; Morphinans; Morphine; Naloxone; Neuroblastoma; Receptors, Opioid | 1986 |
Phosphatidylinositol turnover in neuroblastoma cells: regulation by bradykinin, acetylcholine, but not mu- and delta-opioid receptors.
Topics: Acetylcholine; Animals; Bradykinin; Cell Line; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Etorphine; Mice; Phosphatidylinositols; Rats; Receptors, Opioid | 1986 |
Characterization of kappa opioid receptors in neurosecretosomes from bovine posterior pituitary.
Topics: Animals; Cattle; Cytoplasmic Granules; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Etorphine; Kinetics; Microscopy, Electron; Pituitary Gland, Posterior; Receptors, Opioid; Receptors, Opioid, kappa | 1987 |
[Characterization of opioid receptors in the golden hamster brain].
Topics: Animals; Binding, Competitive; Brain; Brain Chemistry; Cricetinae; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Etorphine; Female; Male; Mesocricetus; Radioligand Assay; Receptors, Opioid | 1986 |
Application of receptor theory provides further evidence for the existence of the epsilon-opioid receptor in rat vas deferens.
Topics: Animals; beta-Endorphin; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Etorphine; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; Receptors, Opioid; Vas Deferens | 1984 |
Kappa 3: a novel subtype of the kappa opioid site in bovine adrenal medulla, highly selective for Met-enkephalin-Arg6-Phe7.
Topics: Adrenal Medulla; Animals; Cattle; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Etorphine; In Vitro Techniques; Narcotics; Receptors, Opioid; Receptors, Opioid, kappa | 1984 |
Mechanisms of multiple cellular adaptation processes in clonal cell lines during chronic opiate treatment.
Topics: Adaptation, Physiological; Adenylyl Cyclases; Animals; Cell Line; Clone Cells; Cytosol; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Etorphine; Glioma; Guanylyl Imidodiphosphate; Lanthanum; Mice; Naloxone; Narcotics; Neuroblastoma; Rats; Receptors, Opioid; Sodium; Time Factors | 1984 |
Solubilization in high yield of opioid receptors retaining high-affinity delta, mu and kappa binding sites.
Topics: Animals; Binding Sites; Brain Chemistry; Cell Membrane; Chemical Precipitation; Detergents; Digitonin; Drug Stability; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Etorphine; Magnesium; Peptide Fragments; Polyethylene Glycols; Rats; Receptors, Opioid; Solubility | 1984 |
Opiates stimulate low Km GTPase in brain.
Topics: Adenylyl Cyclase Inhibitors; Animals; Brain; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Etorphine; GTP Phosphohydrolases; Guanosine Triphosphate; Male; Naloxone; Phosphoric Monoester Hydrolases; Rats; Rats, Inbred Strains; Tissue Distribution | 1984 |
Mosaic distribution of opiate receptors, parafascicular projections and acetylcholinesterase in rat striatum.
Topics: Acetylcholinesterase; Animals; Axonal Transport; Caudate Nucleus; Corpus Striatum; Enkephalin, Leucine-2-Alanine; Enkephalins; Etorphine; Leucine; Naloxone; Proline; Rats; Receptors, Opioid | 1981 |
A selective distribution pattern of different opiate receptors in certain areas of rat brain as revealed by in vitro autoradiography.
Topics: Animals; Autoradiography; Brain; Enkephalin, Leucine-2-Alanine; Enkephalins; Etorphine; Male; Rats; Receptors, Opioid | 1981 |
Naltrexone-induced opiate receptor supersensitivity.
Topics: Animals; Brain; Dihydromorphine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Etorphine; Female; Guanosine Triphosphate; Naloxone; Naltrexone; Rats; Rats, Inbred Strains; Receptors, Opioid | 1982 |
Opiate receptor-mediated inhibition of catecholamine release in primary cultures of bovine adrenal chromaffin cells.
Topics: Acetylcholine; Adrenal Medulla; Animals; beta-Endorphin; Catecholamines; Cattle; Cells, Cultured; Chromaffin Granules; Chromaffin System; Cyclazocine; Dihydromorphine; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Etorphine; Phenazocine; Receptors, Opioid | 1982 |
Evidence for multiple "Kappa" binding sites by use of opioid peptides in the guinea-pig lumbo-sacral spinal cord.
Topics: Animals; Binding Sites; Cyclazocine; Dihydromorphine; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Etorphine; Guinea Pigs; Radioligand Assay; Receptors, Opioid; Receptors, Opioid, kappa; Spinal Cord | 1982 |
Multiple opiate binding sites in the central nervous system of the rabbit. Large predominance of a mu subtype in the cerebellum and characterization of a kappa subtype in the thalamus.
Topics: Animals; Binding, Competitive; Central Nervous System; Cerebellum; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Etorphine; In Vitro Techniques; Membranes; Rabbits; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Thalamus | 1983 |
Functional opiate receptor in mouse vas deferens: evidence for a complex interaction.
Topics: Animals; Arylsulfatases; beta-Endorphin; Dose-Response Relationship, Drug; Drug Interactions; Endorphins; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Etorphine; Male; Mice; Mice, Inbred ICR; Morphine; Muscle Contraction; Naloxone; Receptors, Opioid; Sulfatases; Vas Deferens | 1983 |
Further evidence for an opioid receptor complex.
Topics: Animals; Brain Chemistry; Cerebral Cortex; Corpus Striatum; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Etorphine; In Vitro Techniques; Rats; Receptors, Opioid | 1983 |
A selective role for delta-receptors in the regulation of opioid-induced changes in seizure threshold.
Topics: Animals; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Etorphine; Male; Meperidine; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Seizures; Sensory Thresholds | 1983 |
Opiate binding to subcellular fractions from guinea pig ileum.
Topics: Animals; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Etorphine; Guinea Pigs; Ileum; In Vitro Techniques; Receptors, Opioid; Subcellular Fractions | 1984 |
Effect of digitonin on the binding of opiate agonists and antagonists to membrane-bound and soluble opioid binding sites.
Topics: Animals; Brain; Bufo marinus; Digitonin; Diprenorphine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Etorphine; Male; Naloxone; Oxymorphone; Rats; Rats, Inbred Strains; Receptors, Opioid; Species Specificity | 1984 |
Chronic ethanol changes opiate receptor function in rat striatum.
Topics: Animals; Corpus Striatum; Dihydromorphine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Ethanol; Etorphine; Male; Rats; Receptors, Opioid | 1984 |
Characterization and down-regulation of opiate receptors in aggregating fetal rat brain cells.
Topics: Animals; Brain; Cell Aggregation; Cells, Cultured; Dihydromorphine; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Etorphine; Fetus; Molecular Conformation; Rats; Rats, Inbred Strains; Receptors, Opioid | 1984 |
Bremazocine induces antinociception, but prevents opioid-induced constipation and catatonia in rats and precipitates withdrawal in morphine-dependent rats.
Topics: Analgesics; Animals; Benzomorphans; Catatonia; Constipation; Dose-Response Relationship, Drug; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Etorphine; Gastrointestinal Motility; Humans; Male; Morphinans; Morphine; Naloxone; Rats; Substance Withdrawal Syndrome; Substance-Related Disorders | 1984 |
Antagonists at excitatory opioid receptors on sensory neurons in culture increase potency and specificity of opiate analgesics and attenuate development of tolerance/dependence.
Topics: Analgesics; Animals; Cells, Cultured; Diprenorphine; Drug Tolerance; Electrophysiology; Enkephalin, Leucine-2-Alanine; Etorphine; Ganglia, Spinal; Mice; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Neurons, Afferent; Opioid-Related Disorders | 1994 |
Agonist-induced state of the delta-opioid receptor that discriminates between opioid peptides and opiate alkaloids.
Topics: Alkaloids; Binding, Competitive; Cells, Cultured; Endorphins; Enkephalin, Leucine-2-Alanine; Etorphine; GTP-Binding Proteins; Narcotics; Receptors, Opioid, delta | 1993 |
The antiproliferative effect of opioid receptor agonists on the T47D human breast cancer cell line, is partially mediated through opioid receptors.
Topics: Adenocarcinoma; Amino Acid Sequence; Binding Sites; Breast Neoplasms; Cell Division; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Ethylketocyclazocine; Etorphine; Humans; Molecular Sequence Data; Morphine; Narcotic Antagonists; Opioid Peptides; Receptors, Opioid; Tumor Cells, Cultured | 1996 |
Opioid regulation of the mouse delta-opioid receptor expressed in human embryonic kidney 293 cells.
Topics: Adenylyl Cyclases; Animals; Antibodies, Monoclonal; Cell Line; Colforsin; Cyclic AMP; Down-Regulation; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Etorphine; GTP-Binding Proteins; Humans; Methadone; Mice; Morphine; Point Mutation; Radioligand Assay; Receptors, Opioid, delta; Signal Transduction; Structure-Activity Relationship | 1997 |
Opioid peptide receptor studies. 7. The methylfentanyl congener RTI-4614-4 and its four enantiomers bind to different domains of the rat mu opioid receptor.
Topics: Affinity Labels; Analgesics; Analgesics, Opioid; Animals; Binding Sites; Binding, Competitive; COS Cells; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; Etorphine; Fentanyl; Melphalan; Membrane Proteins; Protein Structure, Tertiary; Radioligand Assay; Rats; Receptors, Opioid, mu; Recombinant Fusion Proteins; Stereoisomerism | 1998 |
Differential effects of opioid agonists on G protein expression in CHO cells expressing cloned human opioid receptors.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Opioid; Animals; Benzamides; Blotting, Western; CHO Cells; Cricetinae; Cricetulus; Diterpenes, Clerodane; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Etorphine; Female; Furans; Gene Expression; GTP-Binding Protein alpha Subunits, G12-G13; GTP-Binding Protein alpha Subunits, Gi-Go; Humans; Morphine; Oligopeptides; Piperazines; Pyrones; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu | 2008 |
delta-Opioid receptors stimulate ERK1/2 activity in NG108-15 hybrid cells by integrin-mediated transactivation of TrkA receptors.
Topics: Cell Adhesion; Enkephalin, Leucine-2-Alanine; Etorphine; Glioma; Humans; Hybrid Cells; Integrins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Naloxone; Neuroblastoma; Neurons; Oligopeptides; Protein Kinase Inhibitors; Receptor, trkA; Receptors, Opioid, delta; Transcriptional Activation; Tyrphostins | 2008 |
Delta-opioid receptors activate ERK/MAP kinase via integrin-stimulated receptor tyrosine kinases.
Topics: Cells, Cultured; Enkephalin, Leucine-2-Alanine; ErbB Receptors; Estrenes; Etorphine; Focal Adhesion Protein-Tyrosine Kinases; Humans; Integrins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Oligopeptides; Phosphorylation; Protein Kinase C-delta; Pyrrolidinones; Quinazolines; Receptors, Opioid, delta; Type C Phospholipases; Tyrphostins | 2008 |