Page last updated: 2024-08-23

etorphine and 18,19-dihydroetorphine

etorphine has been researched along with 18,19-dihydroetorphine in 59 studies

Research

Studies (59)

TimeframeStudies, this research(%)All Research%
pre-19908 (13.56)18.7374
1990's37 (62.71)18.2507
2000's12 (20.34)29.6817
2010's2 (3.39)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
He, BL; Jin, B; Li, H1
Bian, CF; Xing, SH; Xu, PC1
Bian, CF; Chen, Y; Duan, SM; Jin, GZ; Qin, W; Xing, SH; Yu, YM1
Bian, CF; Qin, W; Xing, SH1
Huang, RH; Xu, X1
Huang, M; Qin, BY; Wang, MY; Yuan, SL1
Huang, M; Qin, BY2
Li, E; Weng, L1
Miao, H; Qin, BY1
Feng, JL; Hu, XY; Liu, F; Luo, Y2
al-Essa, LY; Iwamura, T; Kataoka, T; Kohno, K; Niwa, M; Nozaki, M; Ohta, S; Tsurumi, K1
Kamei, J; Kasuya, Y; Misawa, M; Nagase, H; Suzuki, T1
Kaneto, H; Nakamura, F; Takahashi, M; Tokuyama, S2
Cai, ZJ; Ge, Y; Li, M; Sun, WL1
Iwamoto, Y; Kamei, J; Kasuya, Y; Misawa, M; Nagase, H; Suzuki, T1
Crain, SM; Shen, KF1
Kaneto, H; Takahashi, M; Tokuyama, S1
Lu, XQ; Qin, BY; Wang, DX1
Iwamura, T; Katsumata, S; Minami, M; Nakagawa, T; Satoh, M1
Kaneto, H; Nakamura, F; Nakao, K; Takahashi, M; Tokuyama, S1
Kamei, J; Nagase, H; Suzuki, T1
Feng, J; Hu, X; Liu, F; Luo, Y1
Harris, LS; Kim, SA; Martin, TJ; Smith, JE1
Huang, C; Wang, A; Zhang, Q1
Chen, DH; Miao, H; Qin, BY; Yang, Y1
Beardsley, PM; Harris, LS1
Jin, Y; Wu, L; Xia, Y1
Aceto, MD; Bowman, ER; Harris, LS1
Ling, K; Pei, G; Pu, L; Ren, XH; Yin, DL; Zhao, J1
Bai, HQ; Li, FY; Li, Y; Wu, WR; Zhang, KR; Zheng, JW1
Cai, Z; Chen, J; Ha, Y; Ren, Y; Wang, G; Wang, W; Xie, L; Zhang, K; Zheng, J1
Hairston, CT; Harris, LS; Lutz, PO; Martin, TJ; Porreca, F1
Cheng, LX; Sha, LJ; Zhang, ZX1
Qin, BY; Wang, DX1
Chen, XP; Guo, QD; Shi, TS1
Bai, HQ; Li, N; Li, Y; Wu, WR; Zhang, KR; Zheng, JW1
Chen, MH; Li, QS; Ma, HJ; Shen, Y; Zuo, XJ1
Li, FY; Li, Y; Wu, WR; Zheng, JW1
Liu, ZH; Zhang, KG1
Akil, H; Lee, KO; Traynor, JR; Woods, JH1
Aceto, MD; Harris, LS; Ji, Z; Scates, SM1
Gong, ZH; Liu, JG; Qin, BY2
Hayashi, T; Kawase, M; Morimoto, Y; Ohmori, S; Saito, S2
Hayashi, T; Kawase, M; Morimoto, Y; Ohmori, S; Saito, S; Sugibayashi, K1
Morimoto, Y; Ohmori, S; Sugiyama, Y1
Fang, L; Kawase, M; Morimoto, Y; Ohmori, S; Saito, S1
Benyhe, S; Biyashev, D; Borsodi, A; Garadnay, S; Makleit, S; Marton, J1
Morimoto, Y; Ohmori, S1
Husbands, SM; Lewis, JW1
France, CR; Gauthier, CR; Gerak, LR1
Chen, XJ; Chi, ZQ; He, Y; Jin, WQ; Liu, ZH; Shen, QX; Zhang, HP1
Han, JS; Luo, F; Ming, XY; Wang, W1
Chi, ZQ; Liu, JG; Sun, JF; Tao, YM; Wang, YH; Xu, XJ1
Baily, P; Boom, M; Dahan, A; Niesters, M; Oksche, A; Olofsen, E; Sarton, E; Smith, KJ; van Velzen, M1

Reviews

2 review(s) available for etorphine and 18,19-dihydroetorphine

ArticleYear
Dihydroetorphine: a potent analgesic: pharmacology, toxicology, pharmacokinetics, and clinical effects.
    CNS drug reviews, 2002,Winter, Volume: 8, Issue:4

    Topics: Administration, Cutaneous; Analgesics, Opioid; Animals; Clinical Trials as Topic; Drug Tolerance; Etorphine; Humans; In Vitro Techniques; Opioid-Related Disorders; Pain, Intractable; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu

2002
Opioid ligands having delayed long-term antagonist activity: potential pharmacotherapies for opioid abuse.
    Mini reviews in medicinal chemistry, 2003, Volume: 3, Issue:2

    Topics: Analgesics, Opioid; Animals; Buprenorphine; Drug Evaluation, Preclinical; Etorphine; Humans; Hydromorphone; Ligands; Morphinans; Narcotic Antagonists; Receptors, Opioid, mu; Structure-Activity Relationship; Substance-Related Disorders

2003

Trials

3 trial(s) available for etorphine and 18,19-dihydroetorphine

ArticleYear
[Influence of dihydroetorphine hydrochloride and tramadol on labor pain and umbilical blood gas].
    Zhonghua fu chan ke za zhi, 1995, Volume: 30, Issue:6

    Topics: Analgesia, Obstetrical; Analgesics, Opioid; Blood Gas Analysis; Etorphine; Female; Humans; Tramadol; Umbilical Arteries; Umbilical Veins; Uterine Contraction

1995
[Colonic dialysis therapy of Chinese herbal medicine in abstinance of heroin addicts--report of 75 cases].
    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 1997, Volume: 17, Issue:2

    Topics: Adolescent; Adult; Analgesics, Opioid; Colon; Dialysis; Drugs, Chinese Herbal; Etorphine; Female; Follow-Up Studies; Heroin Dependence; Humans; Male; Methadone

1997
Analgesic and Respiratory Depressant Effects of R-dihydroetorphine: A Pharmacokinetic-Pharmacodynamic Analysis in Healthy Male Volunteers.
    Anesthesiology, 2019, Volume: 131, Issue:6

    Topics: Adolescent; Adult; Analgesia; Analgesics, Opioid; Dose-Response Relationship, Drug; Double-Blind Method; Etorphine; Healthy Volunteers; Humans; Infusions, Intravenous; Male; Middle Aged; Pain Measurement; Respiratory Insufficiency; Young Adult

2019

Other Studies

54 other study(ies) available for etorphine and 18,19-dihydroetorphine

ArticleYear
[Narcotics combined with low-flow nitrous oxide in open-heart surgery].
    Zhonghua wai ke za zhi [Chinese journal of surgery], 1986, Volume: 24, Issue:4

    Topics: Adolescent; Analgesics, Opioid; Anesthesia; Cardiac Surgical Procedures; Child; Etorphine; Female; Fentanyl; Heart Septal Defects, Ventricular; Humans; Male; Morphinans; Nitrous Oxide

1986
[The interactions between dihydroetorphine, L-tetrahydropalmatine, B-7601 and diazepam].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1986, Volume: 21, Issue:8

    Topics: Alkaloids; Anesthesia, General; Anesthesia, Intravenous; Animals; Antipsychotic Agents; Benzilates; Berberine Alkaloids; Diazepam; Dogs; Drug Interactions; Etorphine; Female; Male; Mice; Morphinans; Piperidines; Rabbits

1986
[Interaction of analgesics and l-stepholidine].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1986, Volume: 7, Issue:5

    Topics: Analgesics; Animals; Berberine; Berberine Alkaloids; Dogs; Drug Synergism; Electroencephalography; Etorphine; Female; Heart Rate; Male; Meperidine; Mice; Pain; Rabbits; Respiration; Sensory Thresholds

1986
Relationship between dihydroetorphine and cholinergic system in the inhibition of respiration and heart rate.
    NIDA research monograph, 1986, Volume: 75

    Topics: Animals; Atropine; Cerebral Ventricles; Etorphine; Heart Rate; Injections, Intraventricular; Morphinans; Pilocarpine; Rabbits; Respiration

1986
[Phosphorimetric method for the determination of dihydroetorphine and its application].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1988, Volume: 23, Issue:4

    Topics: Animals; Brain Chemistry; Etorphine; Mice; Morphinans; Rabbits

1988
[Pharmacodynamics and pharmacokinetics of dihydroetorphine hydrochloride administered sublingually in mice and rats].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1988, Volume: 9, Issue:4

    Topics: Administration, Sublingual; Analgesics; Animals; Biological Availability; Etorphine; Female; Male; Mice; Morphinans

1988
[Analgesic and other CNS depressive effects of dihydroetorphine (author's transl)].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1982, Volume: 3, Issue:1

    Topics: Analgesics; Animals; Dogs; Etorphine; Female; Immobilization; Male; Mice; Morphinans; Motor Activity; Nalorphine; Rabbits; Respiration

1982
[Physical dependence of dihydroetorphine in mice and monkeys (author's transl)].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1982, Volume: 3, Issue:2

    Topics: Analgesics; Animals; Etorphine; Female; Humans; Macaca mulatta; Male; Mice; Morphinans; Morphine Dependence; Opioid-Related Disorders; Substance Withdrawal Syndrome

1982
Influences of locus coeruleus lesions and reserpine treatment on opioid physical dependence in rats.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1995, Volume: 16, Issue:2

    Topics: Animals; Body Weight; Etorphine; Female; Locus Coeruleus; Male; Morphine Dependence; Neurons; Opioid-Related Disorders; Rats; Rats, Wistar; Reserpine; Substance Withdrawal Syndrome

1995
Identification of dihydroetorphine in biological fluids by gas chromatography-mass spectrometry.
    Journal of chromatography. B, Biomedical applications, 1995, May-19, Volume: 667, Issue:2

    Topics: Etorphine; Gas Chromatography-Mass Spectrometry; Humans; Imidazoles; Methylene Chloride; Sensitivity and Specificity; Substance-Related Disorders

1995
Opioid receptor interaction and adenylyl cyclase inhibition of dihydroetorphine: direct comparison with etorphine.
    Life sciences, 1995, Volume: 56, Issue:21

    Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Brain; Etorphine; Gerbillinae; Guinea Pigs; Humans; Male; Placenta; Rats; Rats, Wistar; Receptors, Opioid

1995
Antinociceptive effect of dihydroetorphine in diabetic mice.
    European journal of pharmacology, 1995, Feb-24, Volume: 275, Issue:1

    Topics: Analgesia; Analgesics, Opioid; Animals; Binding, Competitive; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Etorphine; Injections, Intraperitoneal; Injections, Intraventricular; Injections, Subcutaneous; Male; Mice; Mice, Inbred ICR; Naloxone; Naltrexone; Narcotic Antagonists; Pain Measurement; Receptors, Opioid, delta; Receptors, Opioid, mu

1995
Physical dependence produced by dihydroetorphine in mice.
    Biological & pharmaceutical bulletin, 1994, Volume: 17, Issue:8

    Topics: Analgesics; Animals; Etorphine; Injections, Intraventricular; Male; Mice; Mice, Inbred Strains; Morphine Dependence; Naloxone; Opioid-Related Disorders; Substance Withdrawal Syndrome

1994
[Monitoring of dihydroetorphine hydrochloride in biological fluid].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1994, Volume: 29, Issue:9

    Topics: Etorphine; Gas Chromatography-Mass Spectrometry; Humans; Substance Abuse Detection

1994
[Clinical assessment of physical dependence potential of dihydroetorphine hydrochloride (DHE)].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1994, Volume: 29, Issue:4

    Topics: Administration, Sublingual; Adolescent; Adult; Analgesics, Opioid; Etorphine; Female; Heroin; Heroin Dependence; Humans; Male; Methadone; Substance Withdrawal Syndrome; Substance-Related Disorders

1994
Antitussive effect of dihydroetorphine in mice.
    European journal of pharmacology, 1994, Aug-01, Volume: 260, Issue:2-3

    Topics: Alkylating Agents; Animals; Antitussive Agents; Cough; Dose-Response Relationship, Drug; Etorphine; Injections, Intraperitoneal; Male; Mice; Naltrexone; Narcotic Antagonists; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu

1994
Antagonists at excitatory opioid receptors on sensory neurons in culture increase potency and specificity of opiate analgesics and attenuate development of tolerance/dependence.
    Brain research, 1994, Feb-14, Volume: 636, Issue:2

    Topics: Analgesics; Animals; Cells, Cultured; Diprenorphine; Drug Tolerance; Electrophysiology; Enkephalin, Leucine-2-Alanine; Etorphine; Ganglia, Spinal; Mice; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Neurons, Afferent; Opioid-Related Disorders

1994
Antinociceptive effect of dihydroetorphine and its tolerance/dependence liability in mice.
    Biological & pharmaceutical bulletin, 1993, Volume: 16, Issue:8

    Topics: Analgesics; Animals; Body Weight; Drug Tolerance; Etorphine; Male; Mice; Mice, Inbred Strains; Morphine; Motor Activity; Naloxone; Naltrexone; Narcotic Antagonists; Pain Measurement; Substance-Related Disorders

1993
Dihydroetorphine is a mu-receptor-selective ligand.
    The Journal of pharmacy and pharmacology, 1995, Volume: 47, Issue:8

    Topics: Analgesics, Opioid; Animals; Binding, Competitive; Brain; Dose-Response Relationship, Drug; Etorphine; Injections, Intraventricular; Mice; Radioligand Assay; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu

1995
Pharmacological study of dihydroetorphine in cloned mu-, delta- and kappa-opioid receptors.
    European journal of pharmacology, 1995, Nov-30, Volume: 291, Issue:3

    Topics: Animals; CHO Cells; Cloning, Molecular; Colforsin; Cricetinae; Etorphine; Narcotic Antagonists; Narcotics; Pertussis Toxin; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Recombinant Proteins; Virulence Factors, Bordetella

1995
A potent mu-opioid receptor agonist, dihydroetorphine, fails to produce the conditioned place preference in mice.
    Japanese journal of pharmacology, 1996, Volume: 71, Issue:4

    Topics: Analgesics, Opioid; Analysis of Variance; Animals; Choice Behavior; Conditioning, Operant; Conditioning, Psychological; Dose-Response Relationship, Drug; Etorphine; Male; Mice; Morphine; Morphine Dependence

1996
Agonist and antagonist properties of dihydroetorphine for mu-opioid receptors in mice.
    Neuroscience letters, 1996, Sep-06, Volume: 215, Issue:2

    Topics: Analgesics, Opioid; Animals; Buprenorphine; Etorphine; Injections, Intraperitoneal; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Morphine; Nociceptors; Pain Measurement; Receptors, Opioid, mu

1996
Antinociceptive effect of dihydroetorphine following various routes of administration: a comparative study with morphine.
    Biological & pharmaceutical bulletin, 1996, Volume: 19, Issue:3

    Topics: Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Etorphine; Male; Mice; Mice, Inbred Strains; Morphine; Pain Measurement

1996
Determination of dihydroetorphine in biological fluids by gas chromatography-mass spectrometry using selected-ion monitoring.
    Journal of chromatography. B, Biomedical applications, 1996, Apr-26, Volume: 679, Issue:1-2

    Topics: Analgesics, Opioid; Calibration; Etorphine; Gas Chromatography-Mass Spectrometry; Humans; Hydrogen-Ion Concentration; Opioid-Related Disorders; Reference Standards; Reproducibility of Results; Solvents

1996
Potent reinforcing effects of dihydroetorphine in rats.
    European journal of pharmacology, 1997, Apr-18, Volume: 324, Issue:2-3

    Topics: Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Etorphine; Fentanyl; Heroin; Male; Morphine; Morphine Derivatives; Rats; Rats, Inbred F344; Substance Withdrawal Syndrome; Substance-Related Disorders

1997
[Effect of dihydroetorphini hydrochloride on mice parturition].
    Zhonghua fu chan ke za zhi, 1996, Volume: 31, Issue:5

    Topics: Abdominal Pain; Analgesics, Opioid; Anesthetics, Local; Animals; Etorphine; Female; Labor, Obstetric; Mice; Morphine; Pregnancy; Procaine

1996
Ultrastructural changes in rat locus coeruleus induced by chronic opioids.
    Acta neuropathologica, 1997, Volume: 94, Issue:2

    Topics: Analgesics; Animals; Endoplasmic Reticulum, Rough; Etorphine; Locus Coeruleus; Male; Morphine; Myelin Sheath; Naloxone; Narcotic Antagonists; Narcotics; Neurons; Polyribosomes; Rats; Rats, Wistar; Synaptic Vesicles

1997
Evaluation of the discriminative stimulus and reinforcing effects of dihydroetorphine.
    Drug and alcohol dependence, 1997, Nov-25, Volume: 48, Issue:2

    Topics: Analgesics, Opioid; Animals; Discrimination Learning; Dose-Response Relationship, Drug; Etorphine; Heroin; Macaca mulatta; Male; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Self Administration; Substance-Related Disorders

1997
[Clinical study on painless labor under drugs combined with acupuncture analgesia].
    Zhen ci yan jiu = Acupuncture research, 1996, Volume: 21, Issue:3

    Topics: Acupressure; Acupuncture Analgesia; Adult; Analgesics, Opioid; Ear, External; Etorphine; Evoked Potentials, Somatosensory; Female; Humans; Labor, Obstetric; Magnetics; Pain Threshold; Pregnancy; Transcutaneous Electric Nerve Stimulation; Uterine Contraction

1996
Etorphines: mu-opioid receptor-selective antinociception and low physical dependence capacity.
    European journal of pharmacology, 1997, Nov-12, Volume: 338, Issue:3

    Topics: Analgesics, Opioid; Animals; Etorphine; Female; Macaca mulatta; Male; Mice; Mice, Inbred ICR; Pain Threshold; Receptors, Opioid, mu; Substance-Related Disorders

1997
Differential neurotoxicity of etorphine-like opiates: lack of correlation with their ability to activate opiate receptors.
    Toxicon : official journal of the International Society on Toxinology, 1998, Volume: 36, Issue:5

    Topics: Animals; Cell Survival; Etorphine; Guanosine 5'-O-(3-Thiotriphosphate); Heroin; Humans; Narcotics; Neuroblastoma; Neurotoxins; PC12 Cells; Rats; Receptors, Opioid; Structure-Activity Relationship; Thebaine; Tumor Cells, Cultured

1998
Involvement of mu-opioid receptors and alpha-adrenoceptors in the immunomodulatory effects of dihydroetorphine.
    European journal of pharmacology, 1998, Jul-17, Volume: 353, Issue:1

    Topics: Adjuvants, Immunologic; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Analgesics, Opioid; Animals; Cell Division; Etorphine; Female; Immunosuppressive Agents; Interleukin-2; Lymphocytes; Mice; Mice, Inbred BALB C; Naloxone; Narcotic Antagonists; Phentolamine; Propranolol; Receptors, Adrenergic, alpha; Receptors, Opioid, mu

1998
Psychic dependent potential of dihydroetorphine.
    The Journal of toxicological sciences, 1998, Volume: 23 Suppl 2

    Topics: Analgesics, Opioid; Animals; Etorphine; Haplorhini; Mice; Opioid-Related Disorders; Rats

1998
Anti-allodynic actions of intravenous opioids in the nerve injured rat: potential utility of heroin and dihydroetorphine against neuropathic pain.
    European journal of pharmacology, 1998, Sep-11, Volume: 357, Issue:1

    Topics: Analgesics, Opioid; Animals; Drug Evaluation; Etorphine; Fentanyl; Heroin; Infusions, Intravenous; Ligation; Male; Morphine; Nerve Compression Syndromes; Pain; Rats; Rats, Inbred F344; Spinal Nerves

1998
[Binding of [3H] dihydroetorphine to opioid receptors in rat brain membrane].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1996, Volume: 17, Issue:3

    Topics: Analgesics, Opioid; Animals; Binding, Competitive; Brain; Cell Membrane; Etorphine; Female; In Vitro Techniques; Male; Rats; Rats, Wistar; Receptors, Opioid

1996
[Studies on transdermal delivery system of dihydroetorphine hydrochloride].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1996, Volume: 31, Issue:10

    Topics: Administration, Cutaneous; Analgesics, Opioid; Animals; Drug Delivery Systems; Etorphine; Rabbits; Rats; Rats, Wistar; Skin

1996
Immunosuppressive effects of dihydroetorphine, a potent narcotic analgesic, in dihydroetorphine-dependent mice.
    European journal of pharmacology, 1999, Feb-05, Volume: 366, Issue:2-3

    Topics: Analgesics, Opioid; Animals; Antibody-Producing Cells; Body Weight; Cell Division; Dose-Response Relationship, Drug; Etorphine; Female; Hypersensitivity, Delayed; Immunosuppressive Agents; Lymphocyte Count; Lymphocyte Subsets; Lymphocytes; Lymphokines; Mice; Mice, Inbred C57BL; Naloxone; Opioid-Related Disorders; Organ Size; Spleen; Substance Withdrawal Syndrome; Thymus Gland

1999
[Decrease of cAMP and increase of amino acids contents in mouse brain after dihydroetorphine tolerance].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1998, Volume: 19, Issue:1

    Topics: Amino Acids; Analgesics, Opioid; Animals; Aspartic Acid; Brain; Cyclic AMP; Drug Tolerance; Etorphine; gamma-Aminobutyric Acid; Glutamic Acid; Mice

1998
Immunosuppressive effects of intravenous self administration of dihydroetorphine on lymphocyte functions in rats.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1998, Volume: 19, Issue:4

    Topics: Animals; Cell Division; Etorphine; Immunosuppressive Agents; Injections, Intravenous; Interleukin-2; Lymphocytes; Male; Rats; Rats, Wistar; Self Administration; Spleen; Substance-Related Disorders

1998
Dihydroetorphine-induced place preference was mediated by dopamine D1 receptors in rats.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1999, Volume: 20, Issue:4

    Topics: Animals; Behavior, Animal; Benzazepines; Dopamine Agonists; Etorphine; Haloperidol; Male; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, Dopamine D2; Spiperone; Sulpiride

1999
Differential binding properties of oripavines at cloned mu- and delta-opioid receptors.
    European journal of pharmacology, 1999, Aug-13, Volume: 378, Issue:3

    Topics: Analgesics, Opioid; Animals; Benzamides; Binding, Competitive; Buprenorphine; Cloning, Molecular; Diprenorphine; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Etorphine; Fentanyl; Guanosine 5'-O-(3-Thiotriphosphate); Morphine; Naloxone; Piperazines; Radioligand Assay; Rats; Receptors, Opioid, delta; Receptors, Opioid, mu; Sulfur Radioisotopes; Thebaine; Tritium; Tumor Cells, Cultured

1999
Dihydroetorphine: physical dependence and stereotypy after continuous infusion in the rat.
    European journal of pharmacology, 2000, Jan-03, Volume: 387, Issue:1

    Topics: Analgesics, Opioid; Animals; Behavior, Animal; Body Weight; Dose-Response Relationship, Drug; Etorphine; Infusions, Parenteral; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Stereotyped Behavior; Substance Withdrawal Syndrome; Substance-Related Disorders; Time Factors

2000
Effects of opioid receptor agonists on cAMP second messenger system.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1999, Volume: 20, Issue:5

    Topics: Adenylyl Cyclases; Analgesics, Opioid; Buprenorphine; Cyclic AMP; Etorphine; Glioma; Humans; Hybrid Cells; Methadone; Morphine; Neuroblastoma; Opioid-Related Disorders; Receptors, Opioid; Receptors, Opioid, delta; Tumor Cells, Cultured

1999
Effects of low-pH treatment on cAMP second messenger system regulated by different opioid agonists.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1999, Volume: 20, Issue:6

    Topics: Adenylyl Cyclases; Analgesics, Opioid; Buprenorphine; Cyclic AMP; Etorphine; Glioma; Humans; Hybrid Cells; Hydrogen-Ion Concentration; Methadone; Morphine; Neuroblastoma; Opioid-Related Disorders; Receptors, Opioid, delta; Tumor Cells, Cultured

1999
Quantitative determination of dihydroetorphine in rat plasma and brain by liquid chromatography-tandem mass spectrometry.
    Journal of chromatography. B, Biomedical sciences and applications, 2000, Apr-14, Volume: 740, Issue:2

    Topics: Analgesics, Opioid; Animals; Brain Chemistry; Buprenorphine; Calibration; Chromatography, High Pressure Liquid; Etorphine; Male; Mass Spectrometry; Quality Control; Rats; Reference Standards; Reproducibility of Results; Solutions

2000
Pharmacokinetic and pharmacodynamic evaluations of a potent analgesic, dihydroetorphine, in hairless rat.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 296, Issue:2

    Topics: Algorithms; Analgesics, Opioid; Animals; Bile; Biological Availability; Biotransformation; Blood Proteins; Central Nervous System; Etorphine; Glucuronides; Injections, Intraventricular; Pain Measurement; Protein Binding; Rats; Rats, Inbred Strains

2001
Transdermal delivery of the potent analgesic dihydroetorphine: kinetic analysis of skin permeation and analgesic effect in the hairless rat.
    The Journal of pharmacy and pharmacology, 2000, Volume: 52, Issue:12

    Topics: Administration, Cutaneous; Analgesics, Opioid; Animals; Bandages; Brain; Etorphine; In Vitro Techniques; Infusion Pumps; Kinetics; Male; Models, Biological; Rats; Rats, Mutant Strains; Skin; Skin Absorption; Solutions; Time Factors

2000
A protective effect against undesirable increase of dihydroetorphine permeation through damaged skin by using pressure-sensitive adhesive tape with an ethylene-vinyl acetate co-polymer membrane.
    Biological & pharmaceutical bulletin, 2001, Volume: 24, Issue:1

    Topics: Adhesives; Analgesics, Opioid; Animals; Etorphine; Permeability; Polyvinyls; Rats; Skin

2001
Tolerance to analgesia and dependence liability by topical application of dihydroetorphine to hairless rats.
    European journal of pharmacology, 2001, Jul-06, Volume: 423, Issue:2-3

    Topics: Administration, Cutaneous; Analgesics, Opioid; Animals; Conditioning, Psychological; Dose-Response Relationship, Drug; Drug Tolerance; Etorphine; Formaldehyde; Inflammation; Infusions, Intravenous; Injections, Subcutaneous; Male; Morphine; Naloxone; Narcotic Antagonists; Rats; Rats, Nude; Substance-Related Disorders; Time Factors; Weight Loss

2001
Biochemical characterisation of newly developed beta-etorphine and beta-dihydroetorphine derivatives.
    European journal of pharmacology, 2002, May-03, Volume: 442, Issue:1-2

    Topics: Animals; Binding, Competitive; Brain; Cell Membrane; Etorphine; Guanosine 5'-O-(3-Thiotriphosphate); Naloxone; Radioligand Assay; Rats; Rats, Wistar; Structure-Activity Relationship; Sulfur Radioisotopes; Tritium

2002
Discriminative stimulus and antinociceptive effects of dihydroetorphine in rhesus monkeys.
    Psychopharmacology, 2003, Volume: 166, Issue:4

    Topics: Analgesics, Opioid; Animals; Discrimination Learning; Etorphine; Female; Macaca mulatta; Male; Morphine; Naltrexone

2003
Binding affinity to and dependence on some opioids in Sf9 insect cells expressing human mu-opioid receptor.
    Acta pharmacologica Sinica, 2003, Volume: 24, Issue:9

    Topics: Analgesics, Opioid; Animals; Baculoviridae; Binding, Competitive; Cells, Cultured; Cyclic AMP; Etorphine; Female; Fentanyl; Heroin; Male; Mice; Opioid-Related Disorders; Receptors, Opioid, mu; Spodoptera; Transfection

2003
Tramadol and dihydroetorphine produce synergistic analgesic effect and postpones acute opiate tolerance in rats.
    Sheng li xue bao : [Acta physiologica Sinica], 2005, Dec-25, Volume: 57, Issue:6

    Topics: Analgesics, Opioid; Animals; Drug Synergism; Drug Tolerance; Etorphine; Female; Male; Pain; Rats; Rats, Wistar; Tramadol

2005
Paradoxical relationship between RAVE (relative activity versus endocytosis) values of several opioid receptor agonists and their liability to cause dependence.
    Acta pharmacologica Sinica, 2010, Volume: 31, Issue:4

    Topics: Analgesics, Opioid; Animals; Cell Membrane; CHO Cells; Colforsin; Cricetinae; Cricetulus; Cyclic AMP; Endocytosis; Etorphine; Fentanyl; Guanosine 5'-O-(3-Thiotriphosphate); Morphine; Opioid-Related Disorders; Receptors, Opioid, mu

2010