Page last updated: 2024-08-23

etoposide and warfarin

etoposide has been researched along with warfarin in 45 studies

Research

Studies (45)

TimeframeStudies, this research(%)All Research%
pre-19904 (8.89)18.7374
1990's7 (15.56)18.2507
2000's17 (37.78)29.6817
2010's14 (31.11)24.3611
2020's3 (6.67)2.80

Authors

AuthorsStudies
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Avdeef, A; Tam, KY1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Chahinian, AP; Comis, RL; Hirsh, V; Holland, JF; Kopel, S; Perry, MC; Propert, KJ; Skarin, A; Ware, JH; Zimmer, B1
Bitran, JD; Ward, K1
Meddens, MJ; Thompson, J; Thörig, L; van Furth, R1
Emeis, JJ; Eulderink, F; Thompson, J; Thörig, L; Van Furth, R1
Chung, HS; Hyun, JW; Kang, SS; Kim, BK; Paik, WH; Park, JG; Sung, MS; Yang, YM1
Hasson, NK; Le, AT; Lum, BL1
Häcker, G; Roloff, S; Wilhelm, S1
Aisner, J; Carey, RW; Eaton, WL; Green, MR; Hammond, S; Herndon, JE; Hollis, DR; Maurer, LH; Perry, MC; Skarin, AT; Zacharski, LL1
Ahles, TA; Aisner, J; Eaton, WL; Green, MR; Herndon, J; Holland, JC; Kornblith, AB; Maurer, LH; Perry, MC; Silberfarb, PM; Zacharski, LL1
Fujita, N; Nagahashi, A; Nagashima, K; Rokudai, S; Tsuruo, T1
Earnshaw, WC; Kaufmann, SH; Kottke, TJ; Martins, LM1
Bruno, AP; d'Orgeix, AT; Laurent, G; Lautier, D; Quillet-Mary, A1
Arrigo, AP; Bruey, JM; Fromentin, A; Garrido, C; Hilpert, S; Paul, C; Solary, E1
Fujise, K; Li, F; Zhang, D1
Gschwendt, B; Helmbach, H; Kern, MA; Kissel, C; Renz, K; Rossmann, E; Schadendorf, D1
Caldarera, CM; Clo, C; Fattori, M; Flamigni, F; Guarnieri, C; Mackintosh, CA; Pegg, AE; Pignatti, C; Stanic', I; Stefanelli, C; Tantini, B1
de Bruin, EC; de Wilde, J; den Otter, I; Medema, JP; Meersma, D; Peltenburg, LT; Schipper, EM1
Caldarera, CM; Facchini, A; Fattori, M; Fiumana, E; Flamigni, F; Pegg, AE; Pignatti, C; Stefanelli, C; Tantini, B1
Ardito, R; Cammarota, A; Di Renzo, N; Gallucci, G; Romano, G; Tartarone, A1
Bailly, C; Cuevas, C; Kluza, J; Lansiaux, A; Otero, G; Tardy, C; Vanhuyse, M1
Chiu, CC; Fang, K; Lin, CH1
Ariyoshi, N; Kitada, M; Koga, H; Nakamura, H; Nakasa, H; Nakaseko, C; Nishimura, M; Saeki, H; Suzuki, T; Tanaka, H; Yamazaki, S1
Anish, C; Bagchi, T; Jinturkar, KA; Kumar, MK; Misra, AR; Panda, AK1
Assavalapsakul, W; Chung, YH; Johnston, RN; Kaewpiboon, C; Koh, SS; Malilas, W; Moon, J; Phuwapraisirisan, P; Surapinit, S; Tip-Pyang, S1
Ishizawa, K; Kagami, S; Okada, N; Watanabe, H1
Chen, PR; Fan, X; Li, J; Lin, J; Liu, Y; Ngai, WSC; Wang, J; Wang, X; Zhang, G; Zhang, H1
Cai, G; Chen, J; Guo, J; Kong, L; Ren, Y; Song, D; Wan, C; Yu, W; Zhang, W; Zhu, J1
Pai, RV; Vavia, PR1
Ansari, MHSH; Azad, R; Bhandari, SV; Burra, PVLS; Dodamani, S; Dofe, VS; Jalalpure, SS; Kamble, DD; Karnik, KS; Lokwani, DK; Sangshetti, JN; Sarkate, AP; Tiwari, SV1
Hu, Y; Li, J; Li, L; Li, X; Shang, H; Tian, Y; Wu, Q; Zou, Z1

Reviews

1 review(s) available for etoposide and warfarin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

3 trial(s) available for etoposide and warfarin

ArticleYear
A randomized trial of anticoagulation with warfarin and of alternating chemotherapy in extensive small-cell lung cancer by the Cancer and Leukemia Group B.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1989, Volume: 7, Issue:8

    Topics: Altretamine; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Lomustine; Lung Neoplasms; Male; Methotrexate; Middle Aged; Mitomycin; Mitomycins; Prognosis; Random Allocation; Remission Induction; Warfarin

1989
Randomized trial of chemotherapy and radiation therapy with or without warfarin for limited-stage small-cell lung cancer: a Cancer and Leukemia Group B study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1997, Volume: 15, Issue:11

    Topics: Adult; Aged; Amsacrine; Anticoagulants; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Disease-Free Survival; Etoposide; Female; Hemorrhage; Humans; Lung Neoplasms; Male; Middle Aged; Recurrence; Survival Analysis; Warfarin

1997
Psychologic and neuropsychologic functioning of patients with limited small-cell lung cancer treated with chemotherapy and radiation therapy with or without warfarin: a study by the Cancer and Leukemia Group B.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1998, Volume: 16, Issue:5

    Topics: Adult; Aged; Anticoagulants; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Cognition; Combined Modality Therapy; Cranial Irradiation; Cyclophosphamide; Doxorubicin; Emotions; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neuropsychological Tests; Trail Making Test; Warfarin

1998

Other Studies

41 other study(ies) available for etoposide and warfarin

ArticleYear
Cheminformatic models to predict binding affinities to human serum albumin.
    Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25

    Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids

2001
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
    Journal of medicinal chemistry, 2010, May-13, Volume: 53, Issue:9

    Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Warfarin, etoposide, and vindesine interactions.
    Cancer treatment reports, 1984, Volume: 68, Issue:5

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Interactions; Etoposide; Humans; Lung Neoplasms; Male; Prothrombin Time; Vinblastine; Vindesine; Warfarin

1984
The role of bacterial adherence in the pathogenesis of infective endocarditis.
    Infection, 1982, Volume: 10, Issue:3

    Topics: Adhesiveness; Animals; Aortic Valve; Bacterial Infections; Bacterial Physiological Phenomena; Dogs; Endocarditis, Bacterial; Etoposide; Fibrin; Humans; In Vitro Techniques; Mechlorethamine; Rabbits; Staphylococcus; Streptococcus; Virulence; Warfarin

1982
Effects of monocytopenia and anticoagulation in experimental Streptococcus sanguis endocarditis.
    British journal of experimental pathology, 1980, Volume: 61, Issue:1

    Topics: Animals; Endocarditis, Bacterial; Endocardium; Etoposide; Granulocytes; Leukocyte Count; Male; Microscopy, Electron; Monocytes; Podophyllotoxin; Rabbits; Streptococcal Infections; Streptococcus sanguis; Warfarin

1980
The cytotoxicity of psoralidin from Psoralea corylifolia.
    Planta medica, 1996, Volume: 62, Issue:4

    Topics: Antineoplastic Agents, Phytogenic; Benzofurans; Cell Survival; Coumarins; Etoposide; Humans; Plants, Medicinal; Seeds; Tumor Cells, Cultured

1996
Enhancement of warfarin response in a patient receiving etoposide and carboplatin chemotherapy.
    The Annals of pharmacotherapy, 1997, Volume: 31, Issue:9

    Topics: Aged; Anticoagulants; Antineoplastic Agents; Atrial Fibrillation; Carboplatin; Drug Interactions; Etoposide; Germinoma; Humans; Male; Mediastinal Neoplasms; Testicular Neoplasms; Warfarin

1997
Inhibition of etoposide-induced apoptotic events by azide.
    Immunology letters, 1997, Volume: 59, Issue:1

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Azides; Coumarins; Etoposide; Flow Cytometry; Fluorescent Dyes; Humans; Jurkat Cells; Oligopeptides; Proto-Oncogene Proteins c-bcl-2; Tetrazolium Salts; Thiazoles; Ultraviolet Rays

1997
Acceleration of apoptotic cell death after the cleavage of Bcl-XL protein by caspase-3-like proteases.
    Oncogene, 1998, Sep-10, Volume: 17, Issue:10

    Topics: Animals; Apoptosis; Aspartic Acid; bcl-X Protein; Binding Sites; Caspase 3; Caspases; Coumarins; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Enzyme Activation; Etoposide; Gene Expression Regulation; Humans; Interleukin-2; Mice; Oligopeptides; Peptide Fragments; Protease Inhibitors; Proto-Oncogene Proteins c-bcl-2; T-Lymphocytes; Transfection

1998
Phosphorylated forms of activated caspases are present in cytosol from HL-60 cells during etoposide-induced apoptosis.
    Blood, 1998, Nov-01, Volume: 92, Issue:9

    Topics: Apoptosis; Caspases; Coumarins; Cysteine Proteinase Inhibitors; Cytosol; Enzyme Activation; Enzyme Precursors; Etoposide; HL-60 Cells; Humans; Kinetics; Neoplasm Proteins; Oligopeptides; Phosphoprotein Phosphatases; Phosphorylation; Poly(ADP-ribose) Polymerases; Protein Processing, Post-Translational

1998
Acute myeloblastic leukemic cells acquire cellular cytotoxicity under genotoxic stress: implication of granzyme B and perforin.
    Blood, 2000, Sep-01, Volume: 96, Issue:5

    Topics: Antigens, CD34; Antineoplastic Agents; Cell Survival; Coumarins; Cytarabine; Cytotoxicity Tests, Immunologic; Daunorubicin; DNA, Antisense; Edetic Acid; Etoposide; Flow Cytometry; Granzymes; HeLa Cells; Humans; Isocoumarins; Jurkat Cells; K562 Cells; Leukemia, Myeloid, Acute; Magnesium Chloride; Membrane Glycoproteins; Perforin; Pore Forming Cytotoxic Proteins; Serine Endopeptidases; Tumor Cells, Cultured; U937 Cells

2000
Differential regulation of HSP27 oligomerization in tumor cells grown in vitro and in vivo.
    Oncogene, 2000, Oct-05, Volume: 19, Issue:42

    Topics: Amino Acid Substitution; Animals; Antineoplastic Agents; Apoptosis; Aspartic Acid; Biopolymers; Caspase 3; Caspase 9; Caspases; Cell Communication; Cell Count; Cell-Free System; Cisplatin; Colorectal Neoplasms; Coumarins; Etoposide; Heat-Shock Proteins; Mice; Molecular Weight; Mutagenesis, Site-Directed; Neoplasm Proteins; Oligopeptides; Phosphorylation; Phosphoserine; Protein Processing, Post-Translational; Rats; Recombinant Fusion Proteins; Transfection; Tumor Cells, Cultured

2000
Characterization of fortilin, a novel antiapoptotic protein.
    The Journal of biological chemistry, 2001, Dec-14, Volume: 276, Issue:50

    Topics: Amino Acid Sequence; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Biomarkers, Tumor; Blotting, Northern; Blotting, Western; Breast Neoplasms; Caspase 3; Caspases; Cell Death; Cell Line; Cloning, Molecular; Coumarins; DNA, Complementary; Dose-Response Relationship, Drug; Enzyme Inhibitors; Etoposide; HeLa Cells; Humans; Immunohistochemistry; Molecular Sequence Data; Neoplasm Proteins; Nuclear Proteins; Nucleic Acid Synthesis Inhibitors; Oligopeptides; Proto-Oncogene Proteins c-bcl-2; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Time Factors; Tissue Distribution; Tumor Cells, Cultured; Tumor Protein, Translationally-Controlled 1; Two-Hybrid System Techniques

2001
Drug resistance towards etoposide and cisplatin in human melanoma cells is associated with drug-dependent apoptosis deficiency.
    The Journal of investigative dermatology, 2002, Volume: 118, Issue:6

    Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Caspases; Cisplatin; Coumarins; Cytochrome c Group; DNA Fragmentation; Drug Resistance, Neoplasm; Enzyme Activation; Etoposide; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Melanoma; Peptide Fragments; Poly(ADP-ribose) Polymerases; RNA, Messenger; Tumor Cells, Cultured

2002
Caspase activation in etoposide-treated fibroblasts is correlated to ERK phosphorylation and both events are blocked by polyamine depletion.
    FEBS letters, 2002, Sep-11, Volume: 527, Issue:1-3

    Topics: Animals; Apoptosis; Caspase Inhibitors; Caspases; Coumarins; Eflornithine; Enzyme Activation; Enzyme Inhibitors; Etoposide; Fibroblasts; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Oligopeptides; Ornithine Decarboxylase Inhibitors; Phosphorylation; Polyamines; Putrescine; Signal Transduction

2002
A serine protease is involved in the initiation of DNA damage-induced apoptosis.
    Cell death and differentiation, 2003, Volume: 10, Issue:10

    Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Blotting, Western; Caspase 2; Caspase 3; Caspase Inhibitors; Caspases; Cell Line; Cell Line, Tumor; Coumarins; Cysteine Proteinase Inhibitors; DNA Damage; Etoposide; Fibroblasts; Flow Cytometry; Humans; Microscopy, Phase-Contrast; Oligopeptides; Peptide Hydrolases; Poly(ADP-ribose) Polymerases; Rats; Serine Endopeptidases; Serine Proteinase Inhibitors; Sulfones; Tumor Necrosis Factor-alpha

2003
Polyamine depletion inhibits etoposide-induced NF-kappaB activation in transformed mouse fibroblasts.
    Amino acids, 2004, Volume: 27, Issue:2

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Caspases; Cell Line, Transformed; Cell Nucleus; Coumarins; DNA; Eflornithine; Enzyme Inhibitors; Etoposide; Fibroblasts; Flavonoids; In Situ Nick-End Labeling; MAP Kinase Signaling System; Mice; NF-kappa B; Phosphorylation; Polyamines; Protein Binding; Time Factors

2004
Venous thromboembolism after high-dose chemotherapy in a patient with Hodgkin's lymphoma receiving the new oral contraceptive ethinylestradiol and drospirenone ("Yasmine").
    Bone marrow transplantation, 2005, Volume: 35, Issue:1

    Topics: Adult; Androstenes; Angiography; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Contraceptives, Oral, Synthetic; Cytarabine; Etoposide; Female; Hodgkin Disease; Humans; Immunotherapy; International Normalized Ratio; Lynestrenol; Melphalan; Mineralocorticoid Receptor Antagonists; Risk; Risk Factors; Time Factors; Venous Thrombosis; Warfarin

2005
Lamellarin D: a novel pro-apoptotic agent from marine origin insensitive to P-glycoprotein-mediated drug efflux.
    Cancer letters, 2005, Apr-28, Volume: 221, Issue:2

    Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Calcium Channel Blockers; Cell Cycle; Coumarins; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Etoposide; Fluoresceins; Heterocyclic Compounds, 4 or More Rings; Isoquinolines; Leukemia P388; Membrane Potentials; Mice; Mitochondria; Rhodamine 123; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Verapamil

2005
Etoposide (VP-16) sensitizes p53-deficient human non-small cell lung cancer cells to caspase-7-mediated apoptosis.
    Apoptosis : an international journal on programmed cell death, 2005, Volume: 10, Issue:3

    Topics: Apoptosis; Carcinoma, Non-Small-Cell Lung; Caspase 7; Caspase Inhibitors; Caspases; Cell Cycle; Cell Line, Tumor; Cell Survival; Coumarins; DNA Fragmentation; Etoposide; Genes, p53; Humans; Lung Neoplasms; Oligopeptides; Poly(ADP-ribose) Polymerases; Tumor Suppressor Protein p53; Up-Regulation

2005
Probable interaction between warfarin and antitumor agents used in R-ESHAP chemotherapy.
    Clinical therapeutics, 2008, Volume: 30, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cytarabine; Drug Interactions; Etoposide; Follow-Up Studies; Humans; Lymphoma, Large B-Cell, Diffuse; Male; Methylprednisolone; Middle Aged; Pulmonary Embolism; Venous Thrombosis; Warfarin

2008
Liposomal formulations of Etoposide and Docetaxel for p53 mediated enhanced cytotoxicity in lung cancer cell lines.
    Biomaterials, 2012, Volume: 33, Issue:8

    Topics: Annexin A5; beta-Galactosidase; Cell Death; Cell Line, Tumor; Chemistry, Pharmaceutical; Coumarins; Deoxyribonucleases; Docetaxel; Electrophoresis, Agar Gel; Electrophoretic Mobility Shift Assay; Etoposide; Flow Cytometry; Fluorescein-5-isothiocyanate; Freeze Drying; Humans; Intracellular Space; Liposomes; Lung Neoplasms; Microscopy, Electron, Transmission; Particle Size; Static Electricity; Taxoids; Transfection; Tumor Suppressor Protein p53

2012
Feroniellin A-induced autophagy causes apoptosis in multidrug-resistant human A549 lung cancer cells.
    International journal of oncology, 2014, Volume: 44, Issue:4

    Topics: Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; ATP Binding Cassette Transporter, Subfamily B; Autophagy; Beclin-1; Cell Line, Tumor; Coumarins; Drug Resistance, Neoplasm; Etoposide; Furans; Glycosides; Humans; Lung Neoplasms; Membrane Proteins; Microfilament Proteins; Nitriles; Promoter Regions, Genetic; RNA Interference; RNA, Small Interfering; Sirolimus; Sulfones; Transcription Factor RelA; Transcription, Genetic

2014
Ifosfamide and etoposide chemotherapy may interact with warfarin, enhancing the warfarin induced anticoagulant response.
    International journal of clinical pharmacology and therapeutics, 2016, Volume: 54, Issue:1

    Topics: Adolescent; Anticoagulants; Cytochrome P-450 CYP2C9 Inhibitors; Drug Interactions; Etoposide; Humans; Ifosfamide; International Normalized Ratio; Male; Rhabdomyosarcoma; Warfarin

2016
Copper-Triggered Bioorthogonal Cleavage Reactions for Reversible Protein and Cell Surface Modifications.
    Journal of the American Chemical Society, 2019, 10-30, Volume: 141, Issue:43

    Topics: Amines; Cell Membrane; Copper; Coumarins; Doxorubicin; Drug Liberation; Etoposide; Green Fluorescent Proteins; HeLa Cells; Humans; Immunoconjugates; Ligands; Lysine-tRNA Ligase; Mutagenesis; Organometallic Compounds; Phenols; Prodrugs; Proof of Concept Study; Protein Interaction Maps; Receptor, ErbB-2

2019
Real-time monitoring of etoposide prodrug activated by hydrogen peroxide with improved safety.
    Journal of materials chemistry. B, 2019, 12-21, Volume: 7, Issue:47

    Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Survival; Coumarins; Drug Liberation; Etoposide; Humans; Hydrogen Peroxide; Mice; Mice, Nude; Microscopy, Confocal; Neoplasms; Prodrugs; Reactive Oxygen Species; Survival Rate; Transplantation, Heterologous; Zebrafish

2019
Chitosan oligosaccharide enhances binding of nanostructured lipid carriers to ocular mucins: Effect on ocular disposition.
    International journal of pharmaceutics, 2020, Mar-15, Volume: 577

    Topics: Administration, Topical; Animals; Antineoplastic Agents, Phytogenic; Chitosan; Coumarins; Drug Carriers; Drug Delivery Systems; Etoposide; Eye; Lipids; Mucins; Nanostructures; Oligosaccharides; Rabbits; Rats; Rats, Sprague-Dawley; Tissue Distribution; Toxicity Tests

2020
One pot synthesis, in silico study and evaluation of some novel flavonoids as potent topoisomerase II inhibitors.
    Bioorganic & medicinal chemistry letters, 2021, 05-15, Volume: 40

    Topics: Antineoplastic Agents; Catalytic Domain; Cell Line, Tumor; Cell Proliferation; Chromones; Computer Simulation; Coumarins; DNA Cleavage; DNA Topoisomerases, Type II; Doxorubicin; Drug Screening Assays, Antitumor; Etoposide; Flavonoids; Humans; Imidazoles; Protein Binding; Structure-Activity Relationship; Topoisomerase II Inhibitors

2021
The Synthesis and Biological Evaluation of Aloe-Emodin-Coumarin Hybrids as Potential Antitumor Agents.
    Molecules (Basel, Switzerland), 2022, Sep-20, Volume: 27, Issue:19

    Topics: Aloe; Anthraquinones; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Coumarins; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Emodin; Etoposide; Humans; Molecular Structure; Structure-Activity Relationship

2022