Page last updated: 2024-08-23

etoposide and vincristine

etoposide has been researched along with vincristine in 44 studies

Research

Studies (44)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	4 (9.09)	18.2507
2000's	21 (47.73)	29.6817
2010's	17 (38.64)	24.3611
2020's	2 (4.55)	2.80

Authors

Authors	Studies
Hansch, C; Khwaja, TA; Selassie, CD	1
Barrows, LR; Ireland, CM; Kokoshka, JM	1
Cole, SP; Deeley, RG; Grant, CE; Hipfner, DR; Loe, DW; Stride, BD	1
Almerico, AM; Barraja, P; Cirrincione, G; Diana, P; La Colla, P; Lauria, A; Marongiu, ME; Minnei, C; Murtas, P; Musiu, C; Pani, A; Passannanti, A	1
Belinsky, MG; Chen, ZS; Kruh, GD; Rea, PA; Zeng, H	1
Huang, L; Humphreys, JE; Morgan, JB; Polli, JW; Serabjit-Singh, CS; Webster, LO; Wring, SA	1
Borchardt, RT; Horie, K; Tang, F	2
Barone, V; Bolognese, A; Correale, G; La Colla, P; Lavecchia, A; Loddo, R; Manfra, M; Mazzoni, O; Murgioni, C; Novellino, E; Pani, A; Serra, I; Setzu, G; Tramontano, E	1
Belinsky, MG; Chen, ZS; Hopper-Borge, E; Kotova, E; Kruh, GD; Shchaveleva, I	1
Allen, JD; Buitelaar, M; Schinkel, AH; Van Dort, SC; van Tellingen, O	1
Dantzig, AH; Godinot, N; Iversen, PW; Perry, WL; Tabas, L; Williams, DC; Xia, X	1
Cole, SP; Deeley, RG; Grant, CE; Nunoya, K; Zhang, D	1
Bolognese, A; Correale, G; La Colla, P; Lavecchia, A; Loddo, R; Manfra, M; Mazzoni, O; Novellino, E; Sanna, G	1
Bacsó, Z; Cianfriglia, M; Fenyvesi, F; Goda, K; Kappelmayer, J; Lustyik, G; Nagy, H; Szabó, G; Szilasi, M	1
Gibbons, S; Kaatz, GW; Zloh, M	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Bastow, KF; Brossi, A; Lee, KH; Morris-Natschke, SL; Nakagawa-Goto, K; Pan, SL; Shi, Q; Teng, CM; Wei, L; Wu, TS	1
Bednarski, PJ; Gastpar, R; Kaufmann, D; Nishino, T; Pojarová, M; Reszka, P; von Angerer, E	1
Lombardo, F; Obach, RS; Waters, NJ	1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM	1
Bednarski, PJ; Kaufmann, D; Kühne, S; Müller, C; Pfaller, T; Pojarová, M; Vogel, S; von Angerer, E	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Chang, CY; Chang, JY; Chiang, YK; Coumar, MS; Hsieh, HP; Kuo, CC; Lai, MJ; Liou, JP; Reddy, GR; Tan, UK; Wu, SY; Yeh, JY	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Benfenati, E; Raska, I; Toropov, AA; Toropova, AP	1
Chen, X; Lin, X; Skolnik, S; Wang, J	1
Chang, CY; Chang, JY; Kuo, CC; Lai, WY; Lee, HY; Liou, JP; Nien, CY; Shih, KH; Wu, CH	1
Ding, N; Li, M; Li, YX; Shi, DK; Zhang, W	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Aridoss, G; Bleeker, NP; Hermanson, DL; Xing, C; Zhou, B	1
Chaniyara, R; Chen, CH; Chen, CW; Chien, SI; Chou, TC; Kakadiya, R; Lee, TC; Lin, LF; Shah, A; Su, TL; Tala, S; Tsai, TH; Zang, X	1
Chang, CY; Chang, JY; Chang, YT; Kuo, CC; Lai, MJ; Lee, HY; Liou, JP; Liu, YM; Mehndiratta, S; Nien, CY; Pan, SL; Su, MC; Wu, JS; Wu, SY	1
Chang, CY; Chang, JY; Chuang, HY; Kuo, CC; Lee, HY; Liou, JP; Yeh, TK	1
Chang, CY; Chang, JY; Chen, MC; Chiang, YF; Kuo, CC; Lai, MJ; Lee, HY; Liou, JP; Mehndiratta, S	1
Burckhardt, G; Flörl, S; Hagos, Y; Kühne, A; Marada, VV	1
Chang, CY; Chang, JY; Chuang, HY; Kuo, CC; Lai, MJ; Lee, HY; Liou, JP	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Chang, SM; Chen, TL; Christian, W; Detroja, D; Hwang, MJ; Lee, TC; Lin, YW; Pidugu, HB; Shah, A; Su, TL; Suen, CS; Wu, MH	1
Chen, Y; Long, L; Wang, J; Xu, Y; Zhang, L	1
Xu, Z; Zhang, L	1
Diao, Q; Gao, F; Gao, M; Sun, Z; Wang, P; Xiao, J	1
Bai, X; Chen, H; De Brabander, JK; Kim, J; Liou, J; McFadden, DG; Posner, B; Povedano, JM; Rallabandi, R; Rice, L; Xie, Y; Ye, X	1

Reviews

3 review(s) available for etoposide and vincristine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Coumarin-containing hybrids and their anticancer activities. European journal of medicinal chemistry, 2019, Nov-01, Volume: 181 Topics: Animals; Antineoplastic Agents; Coumarins; Drug Design; Drug Discovery; Humans; Neoplasms; Structure-Activity Relationship	2019
Recent advances of podophyllotoxin/epipodophyllotoxin hybrids in anticancer activity, mode of action, and structure-activity relationship: An update (2010-2020). European journal of medicinal chemistry, 2020, Dec-15, Volume: 208 Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Drug Resistance, Neoplasm; Humans; Molecular Structure; Podophyllotoxin; Stereoisomerism; Structure-Activity Relationship	2020

Other Studies

41 other study(ies) available for etoposide and vincristine

Article	Year
Structure-activity relationships of antineoplastic agents in multidrug resistance. Journal of medicinal chemistry, 1990, Volume: 33, Issue:7 Topics: Animals; Antineoplastic Agents; Cell Line; Cell Survival; Cricetinae; Dactinomycin; Drug Resistance; Leukemia L1210; Mice; Regression Analysis; Structure-Activity Relationship; Tumor Cells, Cultured	1990
Cell-based screen for identification of inhibitors of tubulin polymerization. Journal of natural products, 1996, Volume: 59, Issue:12 Topics: Animals; Brain Neoplasms; Bucladesine; Cell Differentiation; Drug Screening Assays, Antitumor; Formazans; Glioma; Rats; Tubulin; Tumor Cells, Cultured	1996
Pharmacological characterization of the murine and human orthologs of multidrug-resistance protein in transfected human embryonic kidney cells. Molecular pharmacology, 1997, Volume: 52, Issue:3 Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; ATP-Binding Cassette Transporters; Cells, Cultured; Culture Techniques; Drug Resistance, Neoplasm; Embryo, Mammalian; Estradiol; Glutathione; Humans; Isomerism; Kidney; Leukotriene C4; Membranes; Mice; Multidrug Resistance-Associated Proteins; Phenotype; Transfection; Vincristine	1997
Derivatives of the new ring system indolo[1,2-c]benzo[1,2,3]triazine with potent antitumor and antimicrobial activity. Journal of medicinal chemistry, 1999, Jul-15, Volume: 42, Issue:14 Topics: Anti-Bacterial Agents; Anti-HIV Agents; Anti-Infective Agents; Antifungal Agents; Antineoplastic Agents; Bacteria; Drug Evaluation, Preclinical; Drug Resistance, Multiple; Drug Resistance, Neoplasm; HIV-1; Humans; Microbial Sensitivity Tests; Structure-Activity Relationship; Triazines; Tumor Cells, Cultured	1999
Transport of methotrexate (MTX) and folates by multidrug resistance protein (MRP) 3 and MRP1: effect of polyglutamylation on MTX transport. Cancer research, 2001, Oct-01, Volume: 61, Issue:19 Topics: 3T3 Cells; Animals; ATP-Binding Cassette Transporters; Biological Transport; Drug Resistance, Multiple; Folic Acid; Humans; Leucovorin; Methotrexate; Mice; Multidrug Resistance-Associated Proteins; Osmolar Concentration; Polyglutamic Acid; Tritium	2001
Rational use of in vitro P-glycoprotein assays in drug discovery. The Journal of pharmacology and experimental therapeutics, 2001, Volume: 299, Issue:2 Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Chromatography, Liquid; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Humans; Mass Spectrometry; Pharmacology; Spodoptera	2001
Are MDCK cells transfected with the human MDR1 gene a good model of the human intestinal mucosa? Pharmaceutical research, 2002, Volume: 19, Issue:6 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caco-2 Cells; Cell Line; Digoxin; Dogs; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Genes, MDR; Humans; Intestinal Mucosa; Transfection	2002
Are MDCK cells transfected with the human MRP2 gene a good model of the human intestinal mucosa? Pharmaceutical research, 2002, Volume: 19, Issue:6 Topics: Animals; Caco-2 Cells; Cell Line; Dogs; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Humans; Intestinal Mucosa; Mitochondrial Proteins; Multidrug Resistance-Associated Protein 2; Ribosomal Proteins; Saccharomyces cerevisiae Proteins; Transfection; Vinblastine	2002
Antitumor agents. 1. Synthesis, biological evaluation, and molecular modeling of 5H-pyrido[3,2-a]phenoxazin-5-one, a compound with potent antiproliferative activity. Journal of medicinal chemistry, 2002, Nov-21, Volume: 45, Issue:24 Topics: Antineoplastic Agents; Cell Division; DNA; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Intercalating Agents; Magnetic Resonance Spectroscopy; Models, Molecular; Oxazines; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Thiazoles; Tumor Cells, Cultured	2002
Characterization of the transport properties of human multidrug resistance protein 7 (MRP7, ABCC10). Molecular pharmacology, 2003, Volume: 63, Issue:2 Topics: Biological Transport; Cells, Cultured; Cyclosporine; Estradiol; Glycocholic Acid; Humans; Kinetics; Leukotriene Antagonists; Leukotriene C4; Multidrug Resistance-Associated Proteins; Osmotic Pressure; Propionates; Quinolines; Recombinant Proteins; Transfection	2003
Mouse breast cancer resistance protein (Bcrp1/Abcg2) mediates etoposide resistance and transport, but etoposide oral availability is limited primarily by P-glycoprotein. Cancer research, 2003, Mar-15, Volume: 63, Issue:6 Topics: Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Availability; Biological Transport; Cell Line; Dogs; Drug Resistance, Neoplasm; Etoposide; Male; Mice; Mice, Knockout; Neoplasm Proteins	2003
Cloning and functional characterization of the multidrug resistance-associated protein (MRP1/ABCC1) from the cynomolgus monkey. Molecular cancer therapeutics, 2003, Volume: 2, Issue:3 Topics: Adenosine Triphosphate; Amino Acid Sequence; Animals; Antibiotics, Antineoplastic; Cell Line, Transformed; Cloning, Molecular; Dogs; Drug Resistance, Multiple; Humans; Kidney; Leukotriene C4; Macaca fascicularis; Mice; Molecular Sequence Data; Multidrug Resistance-Associated Proteins; RNA, Messenger; Sequence Homology, Amino Acid; Species Specificity; Transfection	2003
Molecular cloning and pharmacological characterization of rat multidrug resistance protein 1 (mrp1). Drug metabolism and disposition: the biological fate of chemicals, 2003, Volume: 31, Issue:8 Topics: Amino Acid Sequence; Animals; Carrier Proteins; Cell Line; Cloning, Molecular; DNA, Complementary; Doxorubicin; Embryo, Mammalian; Estradiol; Estradiol Congeners; Estrone; Gene Expression Regulation; Humans; Kidney; Leukotriene C4; Mice; Molecular Sequence Data; Multidrug Resistance-Associated Proteins; Mutagenesis, Site-Directed; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Homology, Amino Acid; Species Specificity; Substrate Specificity; Transfection; Tritium	2003
Antitumor agents. 3. Design, synthesis, and biological evaluation of new pyridoisoquinolindione and dihydrothienoquinolindione derivatives with potent cytotoxic activity. Journal of medicinal chemistry, 2004, Feb-12, Volume: 47, Issue:4 Topics: Antineoplastic Agents; Cell Division; Cell Line, Tumor; DNA; Drug Design; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Inhibitory Concentration 50; Intercalating Agents; Isoquinolines; Magnetic Resonance Spectroscopy; Models, Molecular; Pyridines; Structure-Activity Relationship; Thiophenes	2004
Distinct groups of multidrug resistance modulating agents are distinguished by competition of P-glycoprotein-specific antibodies. Biochemical and biophysical research communications, 2004, Mar-19, Volume: 315, Issue:4 Topics: Adenosine Triphosphatases; Animals; Anti-Bacterial Agents; Antibodies, Monoclonal; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding, Competitive; Calcium Channel Blockers; Cyclosporine; Detergents; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flow Cytometry; Fluoresceins; Humans; Ivermectin; Mice; NIH 3T3 Cells; Substrate Specificity	2004
Inhibitors of multidrug resistance (MDR) have affinity for MDR substrates. Bioorganic & medicinal chemistry letters, 2004, Feb-23, Volume: 14, Issue:4 Topics: Anti-Bacterial Agents; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; Biological Transport; Cell Membrane; Drug Resistance, Microbial; Drug Resistance, Multiple; Ligands; Models, Molecular	2004
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
Antitumor agents 253. Design, synthesis, and antitumor evaluation of novel 9-substituted phenanthrene-based tylophorine derivatives as potential anticancer agents. Journal of medicinal chemistry, 2007, Jul-26, Volume: 50, Issue:15 Topics: Alkaloids; Animals; Antineoplastic Agents; Cell Line, Tumor; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Indolizines; Male; Mice; Mice, Nude; Neoplasm Transplantation; Phenanthrenes; Structure-Activity Relationship; Transplantation, Heterologous	2007
[(2-Phenylindol-3-yl)methylene]propanedinitriles inhibit the growth of breast cancer cells by cell cycle arrest in G(2)/M phase and apoptosis. Bioorganic & medicinal chemistry, 2007, Dec-01, Volume: 15, Issue:23 Topics: Animals; Antineoplastic Agents; Apoptosis; Caspase Inhibitors; Cell Cycle; Cell Division; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; G2 Phase; Humans; Indoles; Mammary Neoplasms, Experimental; Mice; Molecular Structure; Nitriles; Stereoisomerism; Structure-Activity Relationship; Tubulin	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship	2008
Aroyl hydrazones of 2-phenylindole-3-carbaldehydes as novel antimitotic agents. Bioorganic & medicinal chemistry, 2008, Jun-15, Volume: 16, Issue:12 Topics: Antimitotic Agents; Benzoates; Caspase 3; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Humans; Hydrazones; Indoles; Pyridines	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Synthesis and structure-activity relationships of 2-amino-1-aroylnaphthalene and 2-hydroxy-1-aroylnaphthalenes as potent antitubulin agents. Journal of medicinal chemistry, 2008, Dec-25, Volume: 51, Issue:24 Topics: Anisoles; Cell Line, Tumor; Cell Proliferation; Chemistry, Pharmaceutical; Drug Design; Drug Screening Assays, Antitumor; Humans; Indoles; Inhibitory Concentration 50; Models, Chemical; Naphthalenes; Neoplasms; Structure-Activity Relationship; Tubulin; Tubulin Modulators	2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
QSPR modeling of octanol/water partition coefficient of antineoplastic agents by balance of correlations. European journal of medicinal chemistry, 2010, Volume: 45, Issue:4 Topics: Antineoplastic Agents; Models, Chemical; Octanols; Quantitative Structure-Activity Relationship; Water	2010
Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2 Topics: Adenosine; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Biological Transport; Caco-2 Cells; Chromatography, Liquid; Dibenzocycloheptenes; Diketopiperazines; Drug Discovery; Heterocyclic Compounds, 4 or More Rings; Humans; Intestinal Absorption; Mass Spectrometry; Models, Biological; Neoplasm Proteins; Pharmaceutical Preparations; Predictive Value of Tests; Propionates; Quinolines; Substrate Specificity	2011
5-Amino-2-aroylquinolines as highly potent tubulin polymerization inhibitors. Part 2. The impact of bridging groups at position C-2. Journal of medicinal chemistry, 2011, Dec-22, Volume: 54, Issue:24 Topics: Aminoquinolines; Angiogenesis Inhibitors; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Colchicine; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Human Umbilical Vein Endothelial Cells; Humans; Hydroxyquinolines; Quinolines; Stilbenes; Structure-Activity Relationship; Sulfones; Tubulin Modulators	2011
Design, synthesis and biological evaluation of novel glycosylated diphyllin derivatives as topoisomerase II inhibitors. European journal of medicinal chemistry, 2012, Volume: 47, Issue:1 Topics: Apoptosis; Benzodioxoles; Cell Cycle Checkpoints; Cell Line, Tumor; Dioxolanes; DNA Fragmentation; DNA Topoisomerases, Type II; Drug Design; Drug Resistance, Multiple; Glycosylation; Humans; Lignans; Structure-Activity Relationship; Topoisomerase II Inhibitors	2012
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
Structure-activity relationship (SAR) study of ethyl 2-amino-6-(3,5-dimethoxyphenyl)-4-(2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate (CXL017) and the potential of the lead against multidrug resistance in cancer treatment. Journal of medicinal chemistry, 2012, Jun-14, Volume: 55, Issue:11 Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzopyrans; Cell Line, Tumor; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Proto-Oncogene Proteins c-bcl-2; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Structure-Activity Relationship	2012
Novel antitumor indolizino[6,7-b]indoles with multiple modes of action: DNA cross-linking and topoisomerase I and II inhibition. Journal of medicinal chemistry, 2013, Feb-28, Volume: 56, Issue:4 Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cross-Linking Reagents; DNA; Drug Screening Assays, Antitumor; Humans; Indoles; Indolizines; Intercalating Agents; Male; Mice; Mice, Nude; Neoplasm Transplantation; Rats; S Phase Cell Cycle Checkpoints; Structure-Activity Relationship; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Transplantation, Heterologous	2013
Furanylazaindoles: potent anticancer agents in vitro and in vivo. Journal of medicinal chemistry, 2013, Oct-24, Volume: 56, Issue:20 Topics: Animals; Antineoplastic Agents; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Design; Female; Heterocyclic Compounds, 2-Ring; HT29 Cells; Humans; Indoles; Inhibitory Concentration 50; Mice, Nude; Molecular Structure; Neoplasms; Polymerization; Sulfonamides; Tubulin; Xenograft Model Antitumor Assays	2013
Antimitotic and vascular disrupting agents: 2-hydroxy-3,4,5-trimethoxybenzophenones. European journal of medicinal chemistry, 2014, Apr-22, Volume: 77 Topics: Antimitotic Agents; Benzophenones; Cell Line, Tumor; Cell Proliferation; Colchicine; Dose-Response Relationship, Drug; HT29 Cells; Human Umbilical Vein Endothelial Cells; Humans; KB Cells; Molecular Structure; Polymerization; Structure-Activity Relationship; Tubulin	2014
Concise syntheses of 7-anilino-indoline-N-benzenesulfonamides as antimitotic and vascular disrupting agents. Bioorganic & medicinal chemistry, 2014, Sep-01, Volume: 22, Issue:17 Topics: Antineoplastic Agents; Capillaries; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; HT29 Cells; Humans; Indoles; KB Cells; Mitosis; Molecular Structure; Polymerization; Structure-Activity Relationship; Sulfonamides; Tubulin; Tubulin Modulators	2014
Interaction of human organic anion transporter polypeptides 1B1 and 1B3 with antineoplastic compounds. European journal of medicinal chemistry, 2015, Mar-06, Volume: 92 Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Line; Humans; Liver-Specific Organic Anion Transporter 1; Molecular Structure; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Peptides; Solute Carrier Organic Anion Transporter Family Member 1B3	2015
Antimitotic and antivascular activity of heteroaroyl-2-hydroxy-3,4,5-trimethoxybenzenes. Bioorganic & medicinal chemistry, 2015, Aug-01, Volume: 23, Issue:15 Topics: Angiogenesis Inhibitors; Antimitotic Agents; Benzene; Binding Sites; Cell Line, Tumor; Cell Proliferation; Chemistry Techniques, Synthetic; Colchicine; Drug Evaluation, Preclinical; Drug Resistance, Neoplasm; HT29 Cells; Human Umbilical Vein Endothelial Cells; Humans; Inhibitory Concentration 50; Structure-Activity Relationship; Tubulin Modulators	2015
Novel indolizino[8,7-b]indole hybrids as anti-small cell lung cancer agents: Regioselective modulation of topoisomerase II inhibitory and DNA crosslinking activities. European journal of medicinal chemistry, 2017, Feb-15, Volume: 127 Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; DNA; DNA Topoisomerases, Type II; Drug Design; Humans; Indoles; Lung Neoplasms; Mice; Small Cell Lung Carcinoma; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Xenograft Model Antitumor Assays	2017
Design, synthesis and antineoplastic activity of novel hybrids of podophyllotoxin and indirubin against human leukaemia cancer cells as multifunctional anti-MDR agents. Bioorganic & medicinal chemistry letters, 2018, 06-01, Volume: 28, Issue:10 Topics: Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding Sites; Down-Regulation; Drug Design; Drug Resistance, Neoplasm; G2 Phase Cell Cycle Checkpoints; Humans; Indoles; JNK Mitogen-Activated Protein Kinases; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Molecular Dynamics Simulation; Multidrug Resistance-Associated Proteins; Podophyllotoxin; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Signal Transduction; Tubulin	2018
A Multipronged Approach Establishes Covalent Modification of β-Tubulin as the Mode of Action of Benzamide Anti-cancer Toxins. Journal of medicinal chemistry, 2020, 11-25, Volume: 63, Issue:22 Topics: Antineoplastic Agents; Benzamides; Binding Sites; Colchicine; Humans; Lung Neoplasms; Microtubules; Protein Conformation; Small Cell Lung Carcinoma; Structure-Activity Relationship; Tubulin; Tubulin Modulators	2020