Page last updated: 2024-08-23

etoposide and vinblastine

etoposide has been researched along with vinblastine in 33 studies

Research

Studies (33)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (3.03)	18.7374
1990's	3 (9.09)	18.2507
2000's	19 (57.58)	29.6817
2010's	10 (30.30)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Hansch, C; Khwaja, TA; Selassie, CD	1
Allison, DL; Glaser, R; Holliday, JE; Kamat, PL; Liebowitz, SM; Moeschberger, ML; Schaller, JP; Witiak, DT	1
Chen, AY; Cheng, CC; Chou, TC; Dong, Q; Liu, DF; Liu, LF; Luo, YL; Savaraj, N; Yu, C	1
Barrows, LR; Ireland, CM; Kokoshka, JM	1
Corbett, TH; Edelstein, M; Hazeldine, ST; Horwitz, JP; Kushner, J; Palomino, E; Paluch, J; Polin, L; White, K	1
Aubé, J; Borchardt, RT; Gao, J; Murase, O; Schowen, RL	1
Huang, L; Humphreys, JE; Morgan, JB; Polli, JW; Serabjit-Singh, CS; Webster, LO; Wring, SA	1
Alqawi, O; Cai, J; Daoud, R; Georges, E; Gros, P; Pelletier, J	1
Borchardt, RT; Horie, K; Tang, F	2
Fischer, H; Huwyler, J; Poli, S; Schwab, D; Tabatabaei, A	1
Thakker, DR; Troutman, MD	1
Bacsó, Z; Cianfriglia, M; Fenyvesi, F; Goda, K; Kappelmayer, J; Lustyik, G; Nagy, H; Szabó, G; Szilasi, M	1
Gibbons, S; Kaatz, GW; Zloh, M	1
Li, Y; Li, YH; Wang, YH; Yang, L; Yang, SL	1
Bacherikov, VA; Chen, CH; Chou, TC; Lin, YW; Liu, LF; Su, TL; Tsai, TJ; Zhang, X	1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Kornienko, A; Magedov, IV; Manpadi, M; Przheval'skii, NM; Rogelj, S; Rozhkova, E; Slambrouck, SV; Steelant, WF	1
Lombardo, F; Obach, RS; Waters, NJ	1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Benfenati, E; Raska, I; Toropov, AA; Toropova, AP	1
Benet, LZ; Brouwer, KL; Chu, X; Dahlin, A; Evers, R; Fischer, V; Giacomini, KM; Hillgren, KM; Hoffmaster, KA; Huang, SM; Ishikawa, T; Keppler, D; Kim, RB; Lee, CA; Niemi, M; Polli, JW; Sugiyama, Y; Swaan, PW; Tweedie, DJ; Ware, JA; Wright, SH; Yee, SW; Zamek-Gliszczynski, MJ; Zhang, L	1
Ghosh, I; Manoharlal, R; Prakash, O; Prasad, R; Puri, N; Sharma, M	1
Glen, RC; Lowe, R; Mitchell, JB	1
Chen, X; Lin, X; Skolnik, S; Wang, J	1
Arefolov, A; Clardy, J; Clarke, AS; Ishihara, K; Marks, KM; Park, ES; Pelish, HE; Ring, JE; Russo, K	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Burckhardt, G; Flörl, S; Hagos, Y; Kühne, A; Marada, VV	1

Reviews

1 review(s) available for etoposide and vinblastine

Article	Year
Membrane transporters in drug development. Nature reviews. Drug discovery, 2010, Volume: 9, Issue:3 Topics: Animals; Computer Simulation; Decision Trees; Drug Approval; Drug Discovery; Drug Evaluation, Preclinical; Drug Interactions; Humans; Membrane Transport Proteins; Mice; Mice, Knockout; Prescription Drugs	2010

Other Studies

32 other study(ies) available for etoposide and vinblastine

Article	Year
Structure-activity relationships of antineoplastic agents in multidrug resistance. Journal of medicinal chemistry, 1990, Volume: 33, Issue:7 Topics: Animals; Antineoplastic Agents; Cell Line; Cell Survival; Cricetinae; Dactinomycin; Drug Resistance; Leukemia L1210; Mice; Regression Analysis; Structure-Activity Relationship; Tumor Cells, Cultured	1990
Bis(bioreductive) alkylating agents: synthesis and biological activity in a nude mouse human carcinoma model. Journal of medicinal chemistry, 1983, Volume: 26, Issue:12 Topics: Animals; Antineoplastic Agents; Benzoquinones; Burkitt Lymphoma; Cell Line; Cisplatin; Drug Resistance; Humans; Methotrexate; Mice; Mice, Nude; Nasopharyngeal Neoplasms; Quinones; Tumor Stem Cell Assay; Vinblastine	1983
Design of antineoplastic agents on the basis of the "2-phenylnaphthalene-type" structural pattern. 2. Synthesis and biological activity studies of benzo]b]naphtho[2,3-d]furan-6,11-dione derivatives. Journal of medicinal chemistry, 1993, Dec-10, Volume: 36, Issue:25 Topics: Antineoplastic Agents; Carcinoma, Small Cell; Cisplatin; DNA Topoisomerases, Type II; Furans; Humans; Leukemia, Promyelocytic, Acute; Naphthoquinones; Structure-Activity Relationship; Tumor Cells, Cultured	1993
Cell-based screen for identification of inhibitors of tubulin polymerization. Journal of natural products, 1996, Volume: 59, Issue:12 Topics: Animals; Brain Neoplasms; Bucladesine; Cell Differentiation; Drug Screening Assays, Antitumor; Formazans; Glioma; Rats; Tubulin; Tumor Cells, Cultured	1996
Design, synthesis, and biological evaluation of analogues of the antitumor agent, 2-(4-[(7-chloro-2-quinoxalinyl)oxy]phenoxy)propionic acid (XK469). Journal of medicinal chemistry, 2001, May-24, Volume: 44, Issue:11 Topics: Animals; Antineoplastic Agents; Drug Design; Drug Screening Assays, Antitumor; Humans; Mice; Quinoxalines; Stereoisomerism; Structure-Activity Relationship; Transplantation, Heterologous; Tumor Cells, Cultured	2001
A functional assay for quantitation of the apparent affinities of ligands of P-glycoprotein in Caco-2 cells. Pharmaceutical research, 2001, Volume: 18, Issue:2 Topics: Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Biological Transport, Active; Caco-2 Cells; Drug Interactions; Humans; Ligands; Models, Theoretical; Paclitaxel; Tritium	2001
Rational use of in vitro P-glycoprotein assays in drug discovery. The Journal of pharmacology and experimental therapeutics, 2001, Volume: 299, Issue:2 Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Chromatography, Liquid; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Humans; Mass Spectrometry; Pharmacology; Spodoptera	2001
Nucleotide binding and nucleotide hydrolysis properties of the ABC transporter MRP6 (ABCC6). Biochemistry, 2002, Jun-25, Volume: 41, Issue:25 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Azides; Beryllium; Cations, Divalent; Fluorescent Dyes; Fluorides; Hydrolysis; Iodine Radioisotopes; Multidrug Resistance-Associated Proteins; Photoaffinity Labels; Pichia; Rats; Recombinant Proteins; Rhodamine 123; Vanadates	2002
Are MDCK cells transfected with the human MDR1 gene a good model of the human intestinal mucosa? Pharmaceutical research, 2002, Volume: 19, Issue:6 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caco-2 Cells; Cell Line; Digoxin; Dogs; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Genes, MDR; Humans; Intestinal Mucosa; Transfection	2002
Are MDCK cells transfected with the human MRP2 gene a good model of the human intestinal mucosa? Pharmaceutical research, 2002, Volume: 19, Issue:6 Topics: Animals; Caco-2 Cells; Cell Line; Dogs; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Humans; Intestinal Mucosa; Mitochondrial Proteins; Multidrug Resistance-Associated Protein 2; Ribosomal Proteins; Saccharomyces cerevisiae Proteins; Transfection; Vinblastine	2002
Comparison of in vitro P-glycoprotein screening assays: recommendations for their use in drug discovery. Journal of medicinal chemistry, 2003, Apr-24, Volume: 46, Issue:9 Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cells, Cultured; Drug Evaluation, Preclinical; Fluoresceins; Fluorescent Dyes; Humans; Indicators and Reagents; Mice; Models, Molecular; Rhodamines; Species Specificity; Swine	2003
Novel experimental parameters to quantify the modulation of absorptive and secretory transport of compounds by P-glycoprotein in cell culture models of intestinal epithelium. Pharmaceutical research, 2003, Volume: 20, Issue:8 Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Blotting, Western; Cells, Cultured; Diffusion; Humans; Intestinal Absorption; Intestinal Mucosa; Models, Biological; Permeability; Pharmaceutical Preparations; Pharmacokinetics	2003
Distinct groups of multidrug resistance modulating agents are distinguished by competition of P-glycoprotein-specific antibodies. Biochemical and biophysical research communications, 2004, Mar-19, Volume: 315, Issue:4 Topics: Adenosine Triphosphatases; Animals; Anti-Bacterial Agents; Antibodies, Monoclonal; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding, Competitive; Calcium Channel Blockers; Cyclosporine; Detergents; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flow Cytometry; Fluoresceins; Humans; Ivermectin; Mice; NIH 3T3 Cells; Substrate Specificity	2004
Inhibitors of multidrug resistance (MDR) have affinity for MDR substrates. Bioorganic & medicinal chemistry letters, 2004, Feb-23, Volume: 14, Issue:4 Topics: Anti-Bacterial Agents; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; Biological Transport; Cell Membrane; Drug Resistance, Microbial; Drug Resistance, Multiple; Ligands; Models, Molecular	2004
Modeling K(m) values using electrotopological state: substrates for cytochrome P450 3A4-mediated metabolism. Bioorganic & medicinal chemistry letters, 2005, Sep-15, Volume: 15, Issue:18 Topics: Computational Biology; Cyclohexanols; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Molecular Structure; Principal Component Analysis; Pyrrolizidine Alkaloids; Quantitative Structure-Activity Relationship; Reproducibility of Results; Substrate Specificity; Venlafaxine Hydrochloride	2005
Potent antitumor 9-anilinoacridines and acridines bearing an alkylating N-mustard residue on the acridine chromophore: synthesis and biological activity. Journal of medicinal chemistry, 2006, Jun-15, Volume: 49, Issue:12 Topics: Acridines; Aminoacridines; Aniline Compounds; Animals; Antineoplastic Agents, Alkylating; Cell Line, Tumor; DNA; DNA Topoisomerases, Type II; Drug Screening Assays, Antitumor; Humans; Male; Mice; Mice, Nude; Neoplasm Transplantation; Nitrogen Mustard Compounds; Structure-Activity Relationship; Transplantation, Heterologous	2006
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
Discovery and investigation of antiproliferative and apoptosis-inducing properties of new heterocyclic podophyllotoxin analogues accessible by a one-step multicomponent synthesis. Journal of medicinal chemistry, 2007, Oct-18, Volume: 50, Issue:21 Topics: Antineoplastic Agents; Apoptosis; Caspase 3; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Screening Assays, Antitumor; Heterocyclic Compounds, 3-Ring; Humans; Lymphocytes; Podophyllotoxin; Pyrazoles; Stereoisomerism; Structure-Activity Relationship	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
QSPR modeling of octanol/water partition coefficient of antineoplastic agents by balance of correlations. European journal of medicinal chemistry, 2010, Volume: 45, Issue:4 Topics: Antineoplastic Agents; Models, Chemical; Octanols; Quantitative Structure-Activity Relationship; Water	2010
Analysis of physico-chemical properties of substrates of ABC and MFS multidrug transporters of pathogenic Candida albicans. European journal of medicinal chemistry, 2010, Volume: 45, Issue:11 Topics: Candida albicans; Membrane Transport Proteins; Saccharomyces cerevisiae; Structure-Activity Relationship; Substrate Specificity	2010
Predicting phospholipidosis using machine learning. Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5 Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine	2010
Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2 Topics: Adenosine; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Biological Transport; Caco-2 Cells; Chromatography, Liquid; Dibenzocycloheptenes; Diketopiperazines; Drug Discovery; Heterocyclic Compounds, 4 or More Rings; Humans; Intestinal Absorption; Mass Spectrometry; Models, Biological; Neoplasm Proteins; Pharmaceutical Preparations; Predictive Value of Tests; Propionates; Quinolines; Substrate Specificity	2011
The selectivity of austocystin D arises from cell-line-specific drug activation by cytochrome P450 enzymes. Journal of natural products, 2011, Apr-25, Volume: 74, Issue:4 Topics: Aflatoxin B1; Aflatoxins; Antineoplastic Agents; Aspergillus; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Cytochrome P-450 Enzyme System; DNA Damage; Drug Resistance, Multiple; Drug Screening Assays, Antitumor; Humans; Molecular Structure	2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
Interaction of human organic anion transporter polypeptides 1B1 and 1B3 with antineoplastic compounds. European journal of medicinal chemistry, 2015, Mar-06, Volume: 92 Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Line; Humans; Liver-Specific Organic Anion Transporter 1; Molecular Structure; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Peptides; Solute Carrier Organic Anion Transporter Family Member 1B3	2015