Page last updated: 2024-08-23

etoposide and verapamil

etoposide has been researched along with verapamil in 110 studies

Research

Studies (110)

Timeframe	Studies, this research(%)	All Research%
pre-1990	13 (11.82)	18.7374
1990's	51 (46.36)	18.2507
2000's	23 (20.91)	29.6817
2010's	22 (20.00)	24.3611
2020's	1 (0.91)	2.80

Authors

Authors	Studies
Aubé, J; Borchardt, RT; Gao, J; Murase, O; Schowen, RL	1
Belinsky, MG; Chen, ZS; Kruh, GD; Rea, PA; Zeng, H	1
Huang, L; Humphreys, JE; Morgan, JB; Polli, JW; Serabjit-Singh, CS; Webster, LO; Wring, SA	1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL	1
Borchardt, RT; Horie, K; Tang, F	2
Belinsky, MG; Chen, ZS; Hopper-Borge, E; Kotova, E; Kruh, GD; Shchaveleva, I	1
Fischer, H; Huwyler, J; Poli, S; Schwab, D; Tabatabaei, A	1
Thakker, DR; Troutman, MD	1
Bacsó, Z; Cianfriglia, M; Fenyvesi, F; Goda, K; Kappelmayer, J; Lustyik, G; Nagy, H; Szabó, G; Szilasi, M	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Cai, W; Hao, Y; Hu, P; Ma, D; Pan, H; Xie, X; Yu, AD; Yu, J; Yuan, J; Zhang, L; Zhu, H	1
Lombardo, F; Obach, RS; Waters, NJ	1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Campillo, NE; Guerra, A; Páez, JA	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Benet, LZ; Brouwer, KL; Chu, X; Dahlin, A; Evers, R; Fischer, V; Giacomini, KM; Hillgren, KM; Hoffmaster, KA; Huang, SM; Ishikawa, T; Keppler, D; Kim, RB; Lee, CA; Niemi, M; Polli, JW; Sugiyama, Y; Swaan, PW; Tweedie, DJ; Ware, JA; Wright, SH; Yee, SW; Zamek-Gliszczynski, MJ; Zhang, L	1
Avdeef, A; Tam, KY	1
Cheung, CC; Fung, KP; Lai, PB; Lee, WY; Liu, KW; Wong, J; Yeung, JH	1
Ghosh, I; Manoharlal, R; Prakash, O; Prasad, R; Puri, N; Sharma, M	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Chen, X; Lin, X; Skolnik, S; Wang, J	1
Arefolov, A; Clardy, J; Clarke, AS; Ishihara, K; Marks, KM; Park, ES; Pelish, HE; Ring, JE; Russo, K	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Esaki, T; Kawashima, H; Komura, H; Kuroda, M; Mizuguchi, K; Natsume-Kitatani, Y; Ohashi, R; Watanabe, R	1
Lafleur, MV; Lankelma, J; Mans, DR; Pinedo, HM; Retèl, J; Schuurhuis, GJ; Treskes, M	1
Carmichael, J; Harris, AL; Houlbrook, S; Kirk, J; Lien, EA; Philip, P; Stuart, NS; Tonkin, K	1
Cowan, KH; Dixon, KH; Horton, J; Kelley, K; Morrow, C; Nakagawa, M; Schneider, E	1
Demant, EJ; Friche, E; Jensen, PB; Sehested, M	1
Dalton, WS; Grogan, TM; Lehnert, M; Miller, TP; Plezia, P; Roe, DJ; Salmon, SE	1
Feng, MR; Grossman, HB; Liebert, M; Mancini, WR; Wagner, JG; Wedemeyer, G; Williams, M	1
Flanigan, P; Freshney, RI; Hamilton, TG; Kaye, SB; Merry, S	1
de Jong, S; de Vries, EG; Mulder, NH; Zijlstra, JG	1
Arnold, ST; Felsted, RL; Politi, PM; Sinha, BK	1
Ideguchi, H; Kato, S; Muta, K; Nawata, H; Nishimura, J	1
Koch, G; Reeve, JG; Twentyman, PR; Wright, KA	1
Larsson, R; Nygren, P	2
Andreeff, M; Howell, SB; Shalinsky, DR	1
Daniel, JC; Levy, SB; Slapak, CA	1
Arnold, A; Figueredo, A; Findlay, B; Goodyear, M; Jones, A; Neville, A; Normandeau, R	1
Aihara, M; Blume, KG; Chao, NJ; Sikic, BI	2
Bennetts, G; Cairo, MS; Sender, L; Toy, C; van de Ven, C	1
Anas, N; Cairo, MS; Sender, L; Siegel, S	1
Ardiet, C; Navarro, C; Sapet, C; Tranchand, B	1
Cheng, YC; Ferguson, PJ; Fisher, MH; Li, DH; Stephenson, J; Zhou, BS	1
Kawatsu, H; Kojima, K; Nishiyama, Y; Shimokata, K; Takagi, E; Yoshida, S	1
Bénard, J; Da Silva, J; Riou, G; Teyssier, JR	1
Ahmedzai, S; Banham, S; Burnett, A; Cunningham, D; Dorward, A; Hutcheon, A; Kaye, S; Lucie, N; Soukop, M	1
Kaye, SB; Merry, S; Smith, JG; Smith, MA	1
Murray, SL; Slater, LM; Stupecky, M; Sweet, P; Wetzel, MW	1
Cheng, YC; Ferguson, PJ	1
Gross, M; Ross, WE; Yalowich, JC; Zucali, JR	1
Ross, WE; Yalowich, JC	2
Lim, CK; Peters, TJ	1
Balis, FM; Bates, SE; Bryant, G; Chabner, BA; Jamis-Dow, C; Klecker, RW; Kohler, DR; Steinberg, SM; Wilson, WH; Wittes, RE	1
Bates, SE; Bryant, G; Fojo, A; Herdt, J; Jaffe, ES; Regis, J; Steinberg, SM; Wilson, WH; Wittes, RE; Zhan, Z	1
Osann, K; Slater, L; Stupecky, M; Sweet, P; Wetzel, M	1
Davey, MW; Davey, RA; Hargrave, RM; Kidman, AD	1
Adler, KM; Brophy, NA; Fisher, GA; Halsey, J; Lum, BL; Sikic, BI; Yahanda, AM	1
Cowie, FJ; Dick, G; Flanagan, RJ; Judson, I; McCarthy, PT; Phillips, M; Pinkerton, CR	1
Yung, BY	1
Arriagada, R; Arvelo, F; Bourgeois, Y; Goguel, AF; Le Chevalier, T; Lizard, G; Poupon, MF	1
Danks, MK; Davies, SL; Hickson, ID; Hill, BT; Hosking, LK; Shellard, SA; Whelan, RD	1
Chang, JH; Grossman, HB; Liebert, M; Shinohara, N; Wedemeyer, G	1
Milroy, R	1
Dong, J; Johdo, O; Naito, M; Seimiya, H; Tatsuta, T; Tsuruo, T	1
Arvelo, F; Bastian, G; Bichat, F; Bourgeois, Y; Grossin, F; Jacrot, M; Le Chevalier, T; Poupon, MF	1
Hasegawa, S; Koga, H; Kotoh, S; Kumazawa, J; Kuwano, M; Naito, S; Yokomizo, A	1
Balkenende, AY; Slaper-Cortenbach, IC; van den Berg, H; van der Schoot, CE; Van Leeuwen, EF; Vervoordeldonk, SF; von dem Borne, AE	1
Gatzemeier, U; Schneider, A; von Pawel, J	1
Ogretmen, B; Safa, AR	1
Alvarez, M; Bates, SE; Chabner, B; Fojo, AT; Hose, C; Kang, YK; Monks, A; Regis, J; Robey, R; Wilson, WH; Zhan, Z	1
Aran, JM; Gottesman, MM; Licht, T; Pastan, I	1
Cowan, KH; Fukuda, M; Ikeda, K; Kohno, S; Matsuo, I; Nakano, R; Narasaki, F; Oka, M; Soda, H; Takatani, H; Terashi, K; Tomonaga, M	1
Ford, PJ; Germann, UA; Harding, MW; Mason, VS; Shlyakhter, D	1
Alken, P; Köhrmann, KU; Kreukler, C; Nebe, T; Siegsmund, MJ; Steidler, A	1
Cianfriglia, M; Frey, BM; Gieseler, F; Lehnert, M; Scheper, RJ; Schmid, L; Schneider, E; Shao, Y; Twentyman, PR; Wyler, B	1
de Tinguy-Moreaud, E; Denois, F; Lagarde, P; Montaudon, D; Pourquier, P; Robert, J	1
Bates, SE; Dickstein, B; Fojo, AT; Gamelin, E; Regis, J; Sandor, VA; Wilson, W; Zhan, Z	1
Allan, WP; Creighton, AM; Fattman, CL; Hasinoff, BB; Kuschak, TI; Thampatty, P; Yalowich, JC	1
Benderra, Z; Manfait, M; Morjani, H; Trussardi, A	1
Cowie, FJ; Pinkerton, CR; Pritchard-Jones, K; Renshaw, J	1
Guo, A; Hu, P; Makhey, VD; Norris, DA; Sinko, PJ; Yan, J	1
Anyanwutaku, I; Chang, YH; Cheng, YC; Gaj, CL	1
Horton, JK; Reuss, L; Vanoye, CG	1
Cretney, E; Johnstone, RW; Smyth, MJ	1
Cory, AH; Cory, JG	1
Eriksen, J; Litman, T; Maare, C; Nielsen, D; Skovsgaard, T	1
Edington, KG; Fairbairn, LJ; Gagen, D; Heyworth, CM	1
Bailly, C; Cuevas, C; Kluza, J; Lansiaux, A; Otero, G; Tardy, C; Vanhuyse, M	1
Balimane, P; Kadiyala, P; Olah, T; Smalley, J; Xin, B	1
Ades, S; Gould, CJ; Jones, GK; Levy, SB; Maxfield, LF	1
Jankovic, D; Kanazir, S; Markovic, ID; Markovic, JZ; Pesic, M; Rakic, L; Ruzdijic, S	1
Cole, B; Epel, D; Hamdoun, A; Thurber, RV	1
Bhatia, PA; Moaddel, R; Wainer, IW	1
Ai, H; Gu, Y; Hao, G; Li, Y; Peng, Y; Sun, J; Wang, G; Wu, X; Zhang, J; Zhang, X; Zheng, Y; Zhou, F	1
Mo, R; Ping, Q; Sun, M; Xiao, Y; Zhang, C	1
Huang, J; Li, G; Si, L; Xue, K; Zhao, G	1
Habicht, KL; Khadeer, MA; Moaddel, R; Shimmo, R; Singh, NS; Wainer, IW	1
Fu, L; Hu, D; Li, Y; Su, L; Yang, F; Zhang, M	1
Coyle, B; Grundy, RG; Jackson, HK; Kerr, ID; Kilday, JP; Liu, JF; Sabnis, DH; Storer, LCD	1

Reviews

4 review(s) available for etoposide and verapamil

Article	Year
Membrane transporters in drug development. Nature reviews. Drug discovery, 2010, Volume: 9, Issue:3 Topics: Animals; Computer Simulation; Decision Trees; Drug Approval; Drug Discovery; Drug Evaluation, Preclinical; Drug Interactions; Humans; Membrane Transport Proteins; Mice; Mice, Knockout; Prescription Drugs	2010
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Clinical reversal of multidrug resistance. Cancer treatment and research, 1994, Volume: 73 Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport, Active; Clinical Trials as Topic; Cyclosporine; Drug Resistance, Multiple; Etoposide; Gene Expression; Gene Expression Regulation, Neoplastic; Humans; Neoplasm Proteins; Neoplasms; Paclitaxel; Pharmaceutical Preparations; Verapamil	1994
Clinical reversal of multidrug resistance. Stem cells (Dayton, Ohio), 1996, Volume: 14, Issue:1 Topics: Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cyclophosphamide; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Etoposide; Humans; Lymphoma, Non-Hodgkin; Prednisone; Verapamil; Vincristine	1996

Trials

9 trial(s) available for etoposide and verapamil

Article	Year
High-dose tamoxifen as an enhancer of etoposide cytotoxicity. Clinical effects and in vitro assessment in p-glycoprotein expressing cell lines. British journal of cancer, 1992, Volume: 66, Issue:5 Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Dose-Response Relationship, Drug; Drug Resistance; Drug Screening Assays, Antitumor; Drug Synergism; Etoposide; Female; Humans; Male; Membrane Glycoproteins; Middle Aged; Neoplasms; Tamoxifen; Tumor Cells, Cultured; Verapamil	1992
Multidrug-resistant myeloma: laboratory and clinical effects of verapamil as a chemosensitizer. Blood, 1991, Jul-01, Volume: 78, Issue:1 Topics: Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance; Etoposide; Humans; Immunohistochemistry; Membrane Glycoproteins; Multiple Myeloma; Verapamil	1991
Clinical trial of continuous infusion verapamil, bolus vinblastine, and continuous infusion VP-16 in drug-resistant pediatric tumors. Cancer research, 1989, Feb-15, Volume: 49, Issue:4 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Child; Child, Preschool; Clinical Trials as Topic; Etoposide; Humans; Infusions, Intravenous; Leukemia; Liver Neoplasms; Neuroblastoma; Verapamil; Vinblastine	1989
Phase I and pharmacokinetic study of the multidrug resistance modulator dexverapamil with EPOCH chemotherapy. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1995, Volume: 13, Issue:8 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cross-Over Studies; Cyclophosphamide; Doxorubicin; Drug Resistance, Multiple; Etoposide; Female; Humans; Hypotension; Leukocyte Count; Lymphoma; Male; Middle Aged; Neutrophils; Platelet Count; Prednisone; Sarcoma; Stereoisomerism; Verapamil; Vincristine	1995
Controlled trial of dexverapamil, a modulator of multidrug resistance, in lymphomas refractory to EPOCH chemotherapy. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1995, Volume: 13, Issue:8 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cross-Over Studies; Cyclophosphamide; Doxorubicin; Drug Resistance, Multiple; Etoposide; Female; Hodgkin Disease; Humans; Lymphoma; Lymphoma, Non-Hodgkin; Male; Middle Aged; Polymerase Chain Reaction; Prednisone; Remission Induction; Stereoisomerism; Verapamil; Vincristine	1995
Clinical reversal of multidrug resistance. Cancer treatment and research, 1994, Volume: 73 Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport, Active; Clinical Trials as Topic; Cyclosporine; Drug Resistance, Multiple; Etoposide; Gene Expression; Gene Expression Regulation, Neoplastic; Humans; Neoplasm Proteins; Neoplasms; Paclitaxel; Pharmaceutical Preparations; Verapamil	1994
Continuous-infusion verapamil with etoposide in relapsed or resistant paediatric cancers. British journal of cancer, 1995, Volume: 71, Issue:4 Topics: Adolescent; Adult; Bone Neoplasms; Child; Child, Preschool; Drug Administration Schedule; Drug Resistance, Multiple; Etoposide; Female; Hodgkin Disease; Humans; Infant; Infusions, Intravenous; Kidney Neoplasms; Male; Neoplasms; Neuroblastoma; Osteosarcoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Rhabdomyosarcoma; Sarcoma, Ewing; Verapamil; Wilms Tumor	1995
A randomised clinical study of verapamil in addition to combination chemotherapy in small cell lung cancer. West of Scotland Lung Cancer Research Group, and the Aberdeen Oncology Group. British journal of cancer, 1993, Volume: 68, Issue:4 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Blood Pressure; Carcinoma, Small Cell; Doxorubicin; Drug Administration Schedule; Drug Resistance; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Survival Analysis; Verapamil; Vincristine	1993
Randomised trial of vindesine and etoposide +/- dexverapamil in advanced non-small cell lung cancer: first results. Journal of cancer research and clinical oncology, 1995, Volume: 121 Suppl 3 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Calcium Channel Blockers; Carcinoma, Non-Small-Cell Lung; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Verapamil; Vindesine	1995

Other Studies

98 other study(ies) available for etoposide and verapamil

Article	Year
A functional assay for quantitation of the apparent affinities of ligands of P-glycoprotein in Caco-2 cells. Pharmaceutical research, 2001, Volume: 18, Issue:2 Topics: Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Biological Transport, Active; Caco-2 Cells; Drug Interactions; Humans; Ligands; Models, Theoretical; Paclitaxel; Tritium	2001
Transport of methotrexate (MTX) and folates by multidrug resistance protein (MRP) 3 and MRP1: effect of polyglutamylation on MTX transport. Cancer research, 2001, Oct-01, Volume: 61, Issue:19 Topics: 3T3 Cells; Animals; ATP-Binding Cassette Transporters; Biological Transport; Drug Resistance, Multiple; Folic Acid; Humans; Leucovorin; Methotrexate; Mice; Multidrug Resistance-Associated Proteins; Osmolar Concentration; Polyglutamic Acid; Tritium	2001
Rational use of in vitro P-glycoprotein assays in drug discovery. The Journal of pharmacology and experimental therapeutics, 2001, Volume: 299, Issue:2 Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Chromatography, Liquid; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Humans; Mass Spectrometry; Pharmacology; Spodoptera	2001
Cheminformatic models to predict binding affinities to human serum albumin. Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25 Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids	2001
Are MDCK cells transfected with the human MDR1 gene a good model of the human intestinal mucosa? Pharmaceutical research, 2002, Volume: 19, Issue:6 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caco-2 Cells; Cell Line; Digoxin; Dogs; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Genes, MDR; Humans; Intestinal Mucosa; Transfection	2002
Are MDCK cells transfected with the human MRP2 gene a good model of the human intestinal mucosa? Pharmaceutical research, 2002, Volume: 19, Issue:6 Topics: Animals; Caco-2 Cells; Cell Line; Dogs; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Humans; Intestinal Mucosa; Mitochondrial Proteins; Multidrug Resistance-Associated Protein 2; Ribosomal Proteins; Saccharomyces cerevisiae Proteins; Transfection; Vinblastine	2002
Characterization of the transport properties of human multidrug resistance protein 7 (MRP7, ABCC10). Molecular pharmacology, 2003, Volume: 63, Issue:2 Topics: Biological Transport; Cells, Cultured; Cyclosporine; Estradiol; Glycocholic Acid; Humans; Kinetics; Leukotriene Antagonists; Leukotriene C4; Multidrug Resistance-Associated Proteins; Osmotic Pressure; Propionates; Quinolines; Recombinant Proteins; Transfection	2003
Comparison of in vitro P-glycoprotein screening assays: recommendations for their use in drug discovery. Journal of medicinal chemistry, 2003, Apr-24, Volume: 46, Issue:9 Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cells, Cultured; Drug Evaluation, Preclinical; Fluoresceins; Fluorescent Dyes; Humans; Indicators and Reagents; Mice; Models, Molecular; Rhodamines; Species Specificity; Swine	2003
Novel experimental parameters to quantify the modulation of absorptive and secretory transport of compounds by P-glycoprotein in cell culture models of intestinal epithelium. Pharmaceutical research, 2003, Volume: 20, Issue:8 Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Blotting, Western; Cells, Cultured; Diffusion; Humans; Intestinal Absorption; Intestinal Mucosa; Models, Biological; Permeability; Pharmaceutical Preparations; Pharmacokinetics	2003
Distinct groups of multidrug resistance modulating agents are distinguished by competition of P-glycoprotein-specific antibodies. Biochemical and biophysical research communications, 2004, Mar-19, Volume: 315, Issue:4 Topics: Adenosine Triphosphatases; Animals; Anti-Bacterial Agents; Antibodies, Monoclonal; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding, Competitive; Calcium Channel Blockers; Cyclosporine; Detergents; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flow Cytometry; Fluoresceins; Humans; Ivermectin; Mice; NIH 3T3 Cells; Substrate Specificity	2004
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Small molecule regulators of autophagy identified by an image-based high-throughput screen. Proceedings of the National Academy of Sciences of the United States of America, 2007, Nov-27, Volume: 104, Issue:48 Topics: Autophagy; Calcium Channel Blockers; Cell Line, Tumor; Drug Evaluation, Preclinical; Fluspirilene; Glioblastoma; Green Fluorescent Proteins; Humans; Intracellular Membranes; Loperamide; Microtubule-Associated Proteins; Mycotoxins; Peptides; Phagosomes; Phosphatidylinositol Phosphates; Pimozide; Protein Kinases; Recombinant Fusion Proteins; Sirolimus; Small Molecule Libraries; TOR Serine-Threonine Kinases; Trifluoperazine; Zinc Fingers	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors. European journal of medicinal chemistry, 2010, Volume: 45, Issue:3 Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability? Journal of medicinal chemistry, 2010, May-13, Volume: 53, Issue:9 Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis	2010
Cytotoxic effects of tanshinones from Salvia miltiorrhiza on doxorubicin-resistant human liver cancer cells. Journal of natural products, 2010, May-28, Volume: 73, Issue:5 Topics: Abietanes; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma, Hepatocellular; Doxorubicin; Drug Resistance, Neoplasm; Humans; Models, Biological; Molecular Structure; Phenanthrenes; Plants, Medicinal; Salvia miltiorrhiza	2010
Analysis of physico-chemical properties of substrates of ABC and MFS multidrug transporters of pathogenic Candida albicans. European journal of medicinal chemistry, 2010, Volume: 45, Issue:11 Topics: Candida albicans; Membrane Transport Proteins; Saccharomyces cerevisiae; Structure-Activity Relationship; Substrate Specificity	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2 Topics: Adenosine; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Biological Transport; Caco-2 Cells; Chromatography, Liquid; Dibenzocycloheptenes; Diketopiperazines; Drug Discovery; Heterocyclic Compounds, 4 or More Rings; Humans; Intestinal Absorption; Mass Spectrometry; Models, Biological; Neoplasm Proteins; Pharmaceutical Preparations; Predictive Value of Tests; Propionates; Quinolines; Substrate Specificity	2011
The selectivity of austocystin D arises from cell-line-specific drug activation by cytochrome P450 enzymes. Journal of natural products, 2011, Apr-25, Volume: 74, Issue:4 Topics: Aflatoxin B1; Aflatoxins; Antineoplastic Agents; Aspergillus; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Cytochrome P-450 Enzyme System; DNA Damage; Drug Resistance, Multiple; Drug Screening Assays, Antitumor; Humans; Molecular Structure	2011
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Development of an Journal of medicinal chemistry, 2021, 03-11, Volume: 64, Issue:5 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Blood-Brain Barrier; Cell Line; Computer Simulation; Endothelial Cells; Gene Knockout Techniques; Humans; Organic Chemicals; Rats, Transgenic	2021
Modulation by D,L-buthionine-S,R-sulphoximine of etoposide cytotoxicity on human non-small cell lung, ovarian and breast carcinoma cell lines. European journal of cancer (Oxford, England : 1990), 1992, Volume: 28A, Issue:8-9 Topics: Antimetabolites, Antineoplastic; Breast Neoplasms; Buthionine Sulfoximine; Carcinoma, Non-Small-Cell Lung; Cisplatin; Doxorubicin; Drug Synergism; Etoposide; Female; Glutathione; Humans; Lung Neoplasms; Methionine Sulfoximine; Ovarian Neoplasms; Tumor Cells, Cultured; Verapamil	1992
Reduced intracellular drug accumulation in the absence of P-glycoprotein (mdr1) overexpression in mitoxantrone-resistant human MCF-7 breast cancer cells. Cancer research, 1992, Nov-15, Volume: 52, Issue:22 Topics: Adenosine Triphosphate; Antibodies; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Breast Neoplasms; Cell Membrane Permeability; Cross Reactions; DNA Topoisomerases, Type II; Doxorubicin; Drug Resistance; Etoposide; Gene Expression; Humans; Intracellular Fluid; Membrane Glycoproteins; Membrane Proteins; Mitoxantrone; Tumor Cells, Cultured; Verapamil	1992
Relationship of VP-16 to the classical multidrug resistance phenotype. Cancer research, 1992, May-15, Volume: 52, Issue:10 Topics: Affinity Labels; Animals; Carbon Radioisotopes; Carcinoma, Ehrlich Tumor; Cell Membrane; Cell Nucleus; Daunorubicin; Drug Resistance; Etoposide; Phenotype; Polysorbates; Tumor Cells, Cultured; Verapamil	1992
Effect of verapamil on the uptake and efflux of etoposide (VP16) in both sensitive and resistant cancer cells. Selective cancer therapeutics, 1991,Summer, Volume: 7, Issue:2 Topics: Animals; Carcinoma, Transitional Cell; Culture Media; Drug Resistance; Etoposide; Glucose; Humans; Kinetics; Leukemia L1210; Mice; Tumor Cells, Cultured; Urinary Bladder Neoplasms; Verapamil	1991
Circumvention of pleiotropic drug resistance in subcutaneous tumours in vivo with verapamil and clomipramine. European journal of cancer (Oxford, England : 1990), 1991, Volume: 27, Issue:1 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Clomipramine; Dactinomycin; Doxorubicin; Drug Resistance; Etoposide; Female; Male; Mice; Mice, Inbred AKR; Osteosarcoma; Verapamil; Vincristine	1991
Reduced DNA topoisomerase II activity and drug-induced DNA cleavage activity in an adriamycin-resistant human small cell lung carcinoma cell line. Cancer research, 1990, Jan-15, Volume: 50, Issue:2 Topics: Amsacrine; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma, Small Cell; Cell Cycle; Cell Division; DNA; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Doxorubicin; Drug Resistance; Etoposide; Humans; Lung Neoplasms; Membrane Glycoproteins; Topoisomerase II Inhibitors; Tumor Cells, Cultured; Verapamil	1990
P-glycoprotein-independent mechanism of resistance to VP-16 in multidrug-resistant tumor cell lines: pharmacokinetic and photoaffinity labeling studies. Molecular pharmacology, 1990, Volume: 37, Issue:6 Topics: Affinity Labels; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Binding, Competitive; Breast Neoplasms; Cricetinae; Cricetulus; Dactinomycin; Doxorubicin; Drug Resistance; Etoposide; Humans; Membrane Glycoproteins; Neoplasm Proteins; Tumor Cells, Cultured; Verapamil; Vinblastine; Vindesine	1990
Mechanisms involved in the development of adriamycin resistance in human leukemic cells. Leukemia research, 1990, Volume: 14, Issue:6 Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Cell Division; Cell Line; DNA Topoisomerases, Type I; Doxorubicin; Drug Resistance; Etoposide; Glutathione Transferase; Humans; In Vitro Techniques; Leukemia, Myeloid; Membrane Glycoproteins; Verapamil; Vincristine	1990
Chemosensitisation by verapamil and cyclosporin A in mouse tumour cells expressing different levels of P-glycoprotein and CP22 (sorcin). British journal of cancer, 1990, Volume: 62, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Calcium-Binding Proteins; Carcinosarcoma; Cell Line; Colchicine; Cyclosporins; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance; Etoposide; Gene Expression; Mammary Neoplasms, Animal; Membrane Glycoproteins; Mice; Neoplasm Proteins; Verapamil; Vincristine	1990
Verapamil and cyclosporin A potentiate the effects of chemotherapeutic drugs in the human medullary thyroid carcinoma TT cell line not expressing the 170 kDa P-glycoprotein. Cancer letters, 1990, Nov-05, Volume: 54, Issue:3 Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Cyclosporins; Daunorubicin; Dose-Response Relationship, Drug; Drug Resistance; Drug Synergism; Etoposide; Humans; Membrane Glycoproteins; Thyroid Neoplasms; Tumor Cells, Cultured; Verapamil; Vincristine	1990
Modulation of drug sensitivity by dipyridamole in multidrug resistant tumor cells in vitro. Cancer research, 1990, Dec-01, Volume: 50, Issue:23 Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma, Squamous Cell; Cell Survival; Colchicine; Dipyridamole; Drug Resistance; Drug Synergism; Etoposide; Humans; In Vitro Techniques; Membrane Glycoproteins; Neoplasm Proteins; Verapamil; Vinblastine	1990
Sequential emergence of distinct resistance phenotypes in murine erythroleukemia cells under adriamycin selection: decreased anthracycline uptake precedes increased P-glycoprotein expression. Cancer research, 1990, Dec-15, Volume: 50, Issue:24 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cell Line; Cell Survival; Daunorubicin; Doxorubicin; Drug Resistance; Etoposide; Kinetics; Leukemia, Experimental; Membrane Glycoproteins; Mice; Mutation; Neoplasm Proteins; Phenotype; Verapamil; Vincristine	1990
Differential in vitro sensitivity of human tumor and normal cells to chemotherapeutic agents and resistance modulators. International journal of cancer, 1991, Jun-19, Volume: 48, Issue:4 Topics: Adenocarcinoma; Antineoplastic Agents; Buthionine Sulfoximine; Cell Division; Cell Line; Cell Survival; Cisplatin; Cyclosporins; Doxorubicin; Drug Screening Assays, Antitumor; Etoposide; Humans; Kidney Neoplasms; Kinetics; Leukemia; Lymphocytes; Methionine Sulfoximine; Neurilemmoma; Tumor Cells, Cultured; Verapamil; Vincristine	1991
Addition of verapamil and tamoxifen to the initial chemotherapy of small cell lung cancer. A phase I/II study. Cancer, 1990, May-01, Volume: 65, Issue:9 Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Doxorubicin; Drug Administration Schedule; Drug Evaluation; Drug Resistance; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Tamoxifen; Time Factors; Verapamil; Vincristine	1990
Modulation of etoposide (VP-16) cytotoxicity by verapamil or cyclosporine in multidrug-resistant human leukemic cell lines and normal bone marrow. Experimental hematology, 1990, Volume: 18, Issue:11 Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cell Division; Cell Survival; Cyclosporins; Drug Resistance; Etoposide; Hematopoietic Stem Cells; Humans; Leukemia; Tumor Cells, Cultured; Verapamil	1990
Combination chemotherapy and verapamil to purge drug resistant leukemia cells from human bone marrow. Progress in clinical and biological research, 1990, Volume: 333 Topics: Bone Marrow; Bone Marrow Transplantation; Cell Division; Cells, Cultured; Colony-Forming Units Assay; Drug Interactions; Drug Resistance; Etoposide; Humans; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tumor Cells, Cultured; Verapamil	1990
Assessment of purging with multidrug resistance (MDR) modulators and VP-16: results of long-term marrow culture. Experimental hematology, 1990, Volume: 18, Issue:8 Topics: Bone Marrow Cells; Cell Count; Cell Survival; Cells, Cultured; Cyclosporins; Drug Resistance; Etoposide; Granulocytes; Hematopoietic Stem Cells; Humans; Macrophages; Methylcellulose; Verapamil	1990
[Cellular pharmacokinetics of melphalan alone or in combination on human lymphoma or lymphoblasts]. Bulletin du cancer, 1989, Volume: 76, Issue:8 Topics: Antimetabolites; Blastomeres; Burkitt Lymphoma; Buthionine Sulfoximine; Cell Line; Etoposide; Humans; Lymphocytes; Melphalan; Methionine Sulfoximine; Verapamil	1989
Combined modalities of resistance in etoposide-resistant human KB cell lines. Cancer research, 1988, Nov-01, Volume: 48, Issue:21 Topics: DNA Damage; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Doxorubicin; Drug Resistance; Etoposide; Humans; KB Cells; Verapamil; Vincristine	1988
Establishment and characterization of resistant cells to etoposide (VP16) from a mouse breast cancer cell line, FM3A. Japanese journal of cancer research : Gann, 1988, Volume: 79, Issue:8 Topics: Animals; Cell Survival; DNA Topoisomerases, Type II; Drug Resistance; Etoposide; Mammary Neoplasms, Experimental; Mice; Tumor Cells, Cultured; Verapamil	1988
Over-expression of MDR1 gene with no DNA amplification in a multiple-drug-resistant human ovarian carcinoma cell line. International journal of cancer, 1989, Mar-15, Volume: 43, Issue:3 Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Chromosome Deletion; Dactinomycin; Doxorubicin; Drug Resistance; Etoposide; Female; Humans; Mice; Mice, Nude; Ovarian Neoplasms; Phenotype; Tumor Cells, Cultured; Verapamil; Vincristine	1989
The role of VP-16 in the treatment of small-cell lung cancer: studies of the West of Scotland Lung Cancer Group. Seminars in oncology, 1985, Volume: 12, Issue:1 Suppl 2 Topics: Carcinoma, Small Cell; Cyclophosphamide; Drug Resistance; Drug Therapy, Combination; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Podophyllotoxin; Verapamil	1985
Clinically relevant concentrations of verapamil do not enhance the sensitivity of human bone marrow CFU-GM to adriamycin and VP16. British journal of cancer, 1988, Volume: 57, Issue:6 Topics: Bone Marrow; Bone Marrow Cells; Colony-Forming Units Assay; Doxorubicin; Drug Synergism; Etoposide; Hematopoietic Stem Cells; Humans; Verapamil	1988
Verapamil potentiation of VP-16-213 in acute lymphatic leukemia and reversal of pleiotropic drug resistance. Cancer chemotherapy and pharmacology, 1986, Volume: 16, Issue:1 Topics: Animals; Antineoplastic Agents; Cell Survival; Cells, Cultured; Daunorubicin; Dose-Response Relationship, Drug; Drug Resistance; Drug Synergism; Etoposide; Humans; Leukemia L1210; Leukemia P388; Leukemia, Experimental; Leukemia, Lymphoid; Mice; Podophyllotoxin; Verapamil; Vincristine	1986
Transient protection of cultured human cells against antitumor agents by 12-O-tetradecanoylphorbol-13-acetate. Cancer research, 1987, Jan-15, Volume: 47, Issue:2 Topics: Antineoplastic Agents; Cell Division; Cell Survival; Cells, Cultured; Diglycerides; Dose-Response Relationship, Drug; Etoposide; Humans; Methotrexate; Mitoxantrone; Nasopharyngeal Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Type C Phospholipases; Verapamil; Vincristine	1987
Effects of verapamil on etoposide, vincristine, and adriamycin activity in normal human bone marrow granulocyte-macrophage progenitors and in human K562 leukemia cells in vitro. Cancer research, 1985, Volume: 45, Issue:10 Topics: Bone Marrow; Cell Survival; Cells, Cultured; Doxorubicin; Drug Synergism; Etoposide; Granulocytes; Hematopoietic Stem Cells; Humans; Leukemia, Myeloid; Macrophages; Podophyllotoxin; Verapamil; Vincristine	1985
Verapamil-induced augmentation of etoposide accumulation in L1210 cells in vitro. Cancer research, 1985, Volume: 45, Issue:4 Topics: Animals; Cells, Cultured; DNA Repair; Drug Synergism; Etoposide; Leukemia L1210; Mice; Podophyllotoxin; Tritium; Verapamil	1985
Ammonium acetate: a general purpose buffer for clinical applications of high-performance liquid chromatography. Journal of chromatography, 1984, Dec-21, Volume: 316 Topics: Acetates; Bilirubin; Biogenic Amines; Buffers; Catecholamines; Chromatography, High Pressure Liquid; Creatinine; Etoposide; Porphyrins; Retinoids; Teniposide; Verapamil	1984
Potentiation of etoposide-induced DNA damage by calcium antagonists in L1210 cells in vitro. Cancer research, 1984, Volume: 44, Issue:8 Topics: Animals; Cell Division; Cell Nucleus; Cell Survival; DNA Replication; DNA, Neoplasm; Drug Synergism; Etoposide; Gallopamil; Kinetics; Leukemia L1210; Mice; Podophyllotoxin; Verapamil	1984
Comparison of cyclosporin A, verapamil, PSC-833 and cremophor EL as enhancing agents of VP-16 in murine lymphoid leukemias. Leukemia research, 1995, Volume: 19, Issue:8 Topics: Animals; Cell Survival; Cyclosporine; Cyclosporins; Drug Synergism; Etoposide; Glycerol; Leukemia L1210; Leukemia P388; Mice; Survival Analysis; Tumor Cells, Cultured; Verapamil	1995
Development of drug resistance is reduced with idarubicin relative to other anthracyclines. Anti-cancer drugs, 1995, Volume: 6, Issue:3 Topics: Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Cell Survival; Drug Interactions; Drug Resistance, Multiple; Etoposide; Flow Cytometry; Humans; Idarubicin; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Tumor Cells, Cultured; Verapamil	1995
Sphinganine potentiation of cellular differentiation induced by various anti-leukemia drugs in human leukemia cell line HL-60. Naunyn-Schmiedeberg's archives of pharmacology, 1994, Volume: 350, Issue:5 Topics: Antineoplastic Agents; Calcium; Cell Differentiation; Cell Line; Egtazic Acid; Etoposide; Humans; Leukemia, Myeloid; Protein Kinase C; Sphingosine; Verapamil	1994
Response of a multidrug-resistant human small-cell lung cancer xenograft to chemotherapy. Journal of cancer research and clinical oncology, 1993, Volume: 120, Issue:1-2 Topics: Adult; Animals; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma, Small Cell; Carrier Proteins; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Resistance; Etoposide; Female; Flow Cytometry; Humans; Lung Neoplasms; Male; Membrane Glycoproteins; Mice; Mice, Nude; Neoplasm Proteins; Neoplasm Transplantation; Time Factors; Verapamil	1993
Multiple mechanisms of resistance in a series of human testicular teratoma cell lines selected for increasing resistance to etoposide. International journal of cancer, 1994, Apr-15, Volume: 57, Issue:2 Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Carrier Proteins; Cell Survival; DNA; DNA Damage; DNA Topoisomerases, Type II; Drug Resistance; Etoposide; Humans; Male; Membrane Glycoproteins; Teratoma; Testicular Neoplasms; Tumor Cells, Cultured; Verapamil; Vincristine	1994
Evaluation of multiple drug resistance in human bladder cancer cell lines. The Journal of urology, 1993, Volume: 150, Issue:2 Pt 1 Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Carrier Proteins; Doxorubicin; Drug Resistance; Drug Screening Assays, Antitumor; Etoposide; Humans; Membrane Glycoproteins; Neoplasm Proteins; Tumor Cells, Cultured; Urinary Bladder Neoplasms; Verapamil	1993
Difference between the resistance mechanisms of aclacinomycin- and adriamycin-resistant P388 cell lines. Oncology research, 1995, Volume: 7, Issue:5 Topics: Aclarubicin; Animals; Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Nucleus; DNA Topoisomerases, Type II; DNA, Neoplasm; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Etoposide; Humans; Immunoblotting; Leukemia P388; Tumor Cells, Cultured; Verapamil; Vincristine	1995
Adding a reverser (verapamil) to combined chemotherapy overrides resistance in small cell lung cancer xenografts. European journal of cancer (Oxford, England : 1990), 1995, Volume: 31A, Issue:11 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Therapy, Combination; Etoposide; Female; Humans; Lung Neoplasms; Mice; Mice, Nude; Neoplasm Transplantation; Transplantation, Heterologous; Verapamil	1995
Non-P-glycoprotein-mediated atypical multidrug resistance in a human bladder cancer cell line. Japanese journal of cancer research : Gann, 1995, Volume: 86, Issue:11 Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Carcinoma, Transitional Cell; Cisplatin; DNA Topoisomerases, Type II; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Epirubicin; Etoposide; Fluorouracil; Humans; Mitomycin; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Selection, Genetic; Topoisomerase II Inhibitors; Tumor Cells, Cultured; Urinary Bladder Neoplasms; Verapamil; Vinca Alkaloids	1995
Degradation of radioiodinated B cell monoclonal antibodies: inhibition via a FCgamma-receptor-II-mediated mechanism and by drugs. Cancer immunology, immunotherapy : CII, 1996, Volume: 42, Issue:1 Topics: Animals; Antibodies, Monoclonal; Antigens, CD; Antigens, CD19; Antigens, Differentiation, B-Lymphocyte; Antineoplastic Agents; B-Lymphocytes; Biological Transport; Burkitt Lymphoma; Calcium Channel Blockers; Cell Adhesion Molecules; Chloroquine; Colchicine; Etoposide; Humans; Immunoglobulin Isotypes; Immunotoxins; Iodine Radioisotopes; Lectins; Leukemia, B-Cell; Mice; Monensin; Paclitaxel; Radioimmunotherapy; Receptors, IgG; Sialic Acid Binding Ig-like Lectin 2; Verapamil; Vinblastine; Vincristine	1996
Down-regulation of apoptosis-related bcl-2 but not bcl-xL or bax proteins in multidrug-resistant MCF-7/Adr human breast cancer cells. International journal of cancer, 1996, Sep-04, Volume: 67, Issue:5 Topics: Antineoplastic Agents; Apoptosis; Base Sequence; bcl-2-Associated X Protein; bcl-X Protein; Breast Neoplasms; Cyclosporine; Doxorubicin; Drug Resistance, Multiple; Etoposide; Gene Expression Regulation, Neoplastic; Humans; Molecular Sequence Data; Paclitaxel; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; RNA, Messenger; Tumor Cells, Cultured; Verapamil; Vincristine	1996
Complete restoration of glucocerebrosidase deficiency in Gaucher fibroblasts using a bicistronic MDR retrovirus and a new selection strategy. Human gene therapy, 1996, Nov-10, Volume: 7, Issue:17 Topics: Animals; Anthracenes; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Northern; Blotting, Western; Cells, Cultured; Colchicine; Cyclosporins; DNA, Complementary; Doxorubicin; Drug Resistance, Multiple; Etoposide; Fibroblasts; Gaucher Disease; Gene Expression Regulation; Genetic Therapy; Genetic Vectors; Glucosylceramidase; Humans; Mice; Mutagenesis, Insertional; Retroviridae; Transfection; Verapamil	1996
The multidrug resistance-associated protein gene confers drug resistance in human gastric and colon cancers. Japanese journal of cancer research : Gann, 1996, Volume: 87, Issue:12 Topics: Antineoplastic Agents; Camptothecin; Cisplatin; Colonic Neoplasms; Doxorubicin; Etoposide; Genes, MDR; Humans; Irinotecan; Mitomycin; Polymerase Chain Reaction; RNA, Messenger; Stomach Neoplasms; Tumor Cells, Cultured; Verapamil; Vincristine	1996
Chemosensitization and drug accumulation effects of VX-710, verapamil, cyclosporin A, MS-209 and GF120918 in multidrug resistant HL60/ADR cells expressing the multidrug resistance-associated protein MRP. Anti-cancer drugs, 1997, Volume: 8, Issue:2 Topics: Acridines; Affinity Labels; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Cyclosporine; Daunorubicin; Doxorubicin; Drug Resistance, Multiple; Etoposide; Fluoresceins; HL-60 Cells; Humans; Isoquinolines; Multidrug Resistance-Associated Proteins; Piperidines; Pyridines; Quinolines; Tetrahydroisoquinolines; Tritium; Verapamil; Vincristine	1997
Multidrug resistance in androgen-independent growing rat prostate carcinoma cells is mediated by P-glycoprotein. Urological research, 1997, Volume: 25, Issue:1 Topics: Androgens; Animals; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Etoposide; Fluorescent Dyes; Genes, MDR; Male; Methotrexate; Neoplasms, Hormone-Dependent; Paclitaxel; Prostatic Neoplasms; Rats; Rhodamine 123; Rhodamines; Tumor Cells, Cultured; Verapamil; Vinblastine	1997
Intermittent exposure to doxorubicin in vitro selects for multifactorial non-P-glycoprotein-associated multidrug resistance in RPMI 8226 human myeloma cells. British journal of haematology, 1997, Volume: 97, Issue:1 Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Doxorubicin; Drug Interactions; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Etoposide; Humans; Multiple Myeloma; Tumor Cells, Cultured; Verapamil; Vincristine	1997
Differential stabilization of topoisomerase-II-DNA cleavable complexes by doxorubicin and etoposide in doxorubicin-resistant rat glioblastoma cells. European journal of biochemistry, 1997, Apr-15, Volume: 245, Issue:2 Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; DNA; DNA Damage; DNA Topoisomerases, Type II; Doxorubicin; Drug Resistance, Neoplasm; Enzyme Stability; Etoposide; Glioblastoma; Rats; Tumor Cells, Cultured; Verapamil	1997
Expression of the multidrug resistance-associated protein gene in refractory lymphoma: quantitation by a validated polymerase chain reaction assay. Blood, 1997, May-15, Volume: 89, Issue:10 Topics: Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biopsy; Breast Neoplasms; Carcinoma, Small Cell; Cyclophosphamide; DNA, Neoplasm; Doxorubicin; Drug Resistance, Neoplasm; Etoposide; Gene Expression Regulation, Neoplastic; HL-60 Cells; Humans; Lung Neoplasms; Lymphoma; Neoplasm Proteins; Polymerase Chain Reaction; Prednisone; RNA, Messenger; RNA, Neoplasm; Tumor Cells, Cultured; Verapamil; Vincristine	1997
Characterization of a Chinese hamster ovary cell line with acquired resistance to the bisdioxopiperazine dexrazoxane (ICRF-187) catalytic inhibitor of topoisomerase II. Biochemical pharmacology, 1997, Jun-15, Volume: 53, Issue:12 Topics: Aclarubicin; Animals; CHO Cells; Cricetinae; DNA Topoisomerases, Type II; Drug Resistance; Ethylenediamines; Etoposide; Glycine; Mutation; Razoxane; Thiobarbiturates; Topoisomerase II Inhibitors; Verapamil	1997
Role of the vacuolar H+-ATPase in daunorubicin distribution in etoposide-resistant MCF7 cells overexpressing the multidrug-resistance associated protein. International journal of oncology, 1998, Volume: 12, Issue:3 Topics: 4-Chloro-7-nitrobenzofurazan; Adenocarcinoma; ATP Binding Cassette Transporter, Subfamily B, Member 1; Breast Neoplasms; Cell Nucleus; Cholesterol; Cytoplasm; Daunorubicin; Drug Resistance, Multiple; Etoposide; Female; Humans; Norsteroids; Proton-Translocating ATPases; Tumor Cells, Cultured; Vacuolar Proton-Translocating ATPases; Verapamil	1998
Multidrug resistance modulation in rhabdomyosarcoma and neuroblastoma cell lines. International journal of oncology, 1998, Volume: 12, Issue:5 Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma, Small Cell; Cell Survival; Cisplatin; Cyclophosphamide; Cyclosporine; Doxorubicin; Drug Resistance, Multiple; Etoposide; Humans; Kinetics; Lung Neoplasms; Methotrexate; Neuroblastoma; Rhabdomyosarcoma; Time Factors; Tumor Cells, Cultured; Verapamil; Vincristine	1998
Characterization of the regional intestinal kinetics of drug efflux in rat and human intestine and in Caco-2 cells. Pharmaceutical research, 1998, Volume: 15, Issue:8 Topics: Adenosine Triphosphate; Animals; Caco-2 Cells; Colon; Etoposide; Humans; Ileum; Intestinal Mucosa; Jejunum; Protons; Rats; Sodium; Temperature; Verapamil; Vinblastine	1998
Decreased drug accumulation without increased drug efflux in a novel MRP-overexpressing multidrug-resistant cell line. Biochemical pharmacology, 1998, Apr-15, Volume: 55, Issue:8 Topics: Antineoplastic Agents; ATP-Binding Cassette Transporters; Cell Line; Doxorubicin; Drug Resistance, Multiple; Enzyme Inhibitors; Etoposide; Humans; KB Cells; Multidrug Resistance-Associated Proteins; Topoisomerase II Inhibitors; Verapamil; Vincristine	1998
Swelling-activated chloride currents in a drug-sensitive cell line and a P glycoprotein-expressing derivative are underlied by channels with the same pharmacological properties. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 1998, Volume: 8, Issue:5 Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; ATP Binding Cassette Transporter, Subfamily B, Member 1; Breast Neoplasms; Cell Size; Chloride Channels; Colchicine; Cytochalasin D; Cytoskeleton; Electrophysiology; Etoposide; Humans; Hypertonic Solutions; Hypotonic Solutions; Meglumine; Nitrobenzenes; Tumor Cells, Cultured; Verapamil; Vinblastine	1998
P-glycoprotein protects leukemia cells against caspase-dependent, but not caspase-independent, cell death. Blood, 1999, Feb-01, Volume: 93, Issue:3 Topics: Antibodies, Monoclonal; Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caspases; Cytotoxicity, Immunologic; Dexamethasone; DNA, Complementary; Enzyme Inhibitors; Etoposide; Fas Ligand Protein; fas Receptor; Genes, MDR; Granzymes; Humans; Leukemia-Lymphoma, Adult T-Cell; Membrane Glycoproteins; Neoplasm Proteins; Perforin; Pore Forming Cytotoxic Proteins; Recombinant Proteins; Serine Endopeptidases; Transfection; Tumor Necrosis Factor-alpha; Tumor Stem Cell Assay; Ultraviolet Rays; Verapamil; Vinblastine	1999
Comparison of the properties of human breast cancer cells: MCF-7 and MCF-7 cells selected for resistance to etoposide. Advances in enzyme regulation, 2001, Volume: 41 Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Chromatography, High Pressure Liquid; Dactinomycin; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Neoplasm; Etoposide; Flow Cytometry; Humans; Leukotriene Antagonists; Propionates; Protein Synthesis Inhibitors; Quinolines; Tumor Cells, Cultured; Vasodilator Agents; Verapamil; Vinblastine	2001
Expression of P-glycoprotein and multidrug resistance associated protein in Ehrlich ascites tumor cells after fractionated irradiation. International journal of radiation oncology, biology, physics, 2001, Nov-15, Volume: 51, Issue:4 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Calcium Channel Blockers; Carcinoma, Ehrlich Tumor; Daunorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Etoposide; Glutathione; Mice; Neoplasm Proteins; Phenotype; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured; Tumor Stem Cell Assay; Verapamil; Vincristine	2001
Retroviral transfer and expression of human MDR-1 in a murine haemopoietic stem cell line does not alter factor dependence, growth or differentiation characteristics. Leukemia, 2002, Volume: 16, Issue:1 Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Calcium Channel Blockers; Cell Differentiation; Cell Division; Clone Cells; Culture Media, Conditioned; Drug Resistance, Neoplasm; Etoposide; Fluorescent Dyes; Genes, MDR; Hematopoietic Cell Growth Factors; Hematopoietic Stem Cells; Humans; Mice; Peptide Fragments; Receptors, Nerve Growth Factor; Recombinant Fusion Proteins; Rhodamines; Transfection; Verapamil	2002
Lamellarin D: a novel pro-apoptotic agent from marine origin insensitive to P-glycoprotein-mediated drug efflux. Cancer letters, 2005, Apr-28, Volume: 221, Issue:2 Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Calcium Channel Blockers; Cell Cycle; Coumarins; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Etoposide; Fluoresceins; Heterocyclic Compounds, 4 or More Rings; Isoquinolines; Leukemia P388; Membrane Potentials; Mice; Mitochondria; Rhodamine 123; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Verapamil	2005
Development of an on-line extraction turbulent flow chromatography tandem mass spectrometry method for cassette analysis of Caco-2 cell based bi-directional assay samples. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2006, Jan-18, Volume: 830, Issue:2 Topics: Biological Transport; Caco-2 Cells; Cell Membrane Permeability; Chromatography, High Pressure Liquid; Dexamethasone; Etoposide; Furosemide; Humans; Metoprolol; Nadolol; Pharmaceutical Preparations; Propranolol; Quinidine; Rhodamine 123; Spectrometry, Mass, Electrospray Ionization; Sulfasalazine; Verapamil	2006
Selection of non-P-glycoprotein mediated high-level etoposide resistant cell lines by adriamycin with P-gp inhibitors. International journal of oncology, 2006, Volume: 28, Issue:3 Topics: Animals; Antigens, Neoplasm; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Transporters; Blotting, Western; Cell Line, Tumor; Cell Survival; Cyclosporins; Daunorubicin; DNA Topoisomerases, Type II; DNA-Binding Proteins; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Etoposide; Gene Expression Regulation, Neoplastic; Mice; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Verapamil	2006
Induced resistance in the human non small cell lung carcinoma (NCI-H460) cell line in vitro by anticancer drugs. Journal of chemotherapy (Florence, Italy), 2006, Volume: 18, Issue:1 Topics: Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Curcumin; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Etoposide; Glutathione Transferase; Humans; Lung Neoplasms; Multidrug Resistance-Associated Proteins; Paclitaxel; Rhodamines; RNA, Messenger; RNA, Neoplasm; Tumor Cells, Cultured; Verapamil; Vinblastine	2006
The sea urchin embryo as a model for studying efflux transporters: roles and energy cost. Marine environmental research, 2006, Volume: 62 Suppl Topics: Animals; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Division; Cyclosporins; Cytotoxins; Embryo, Nonmammalian; Energy Metabolism; Etoposide; Fluoresceins; Membrane Transport Proteins; Models, Animal; Propionates; Quinolines; Sea Urchins; Verapamil; Vinblastine	2006
The synthesis and characterization of cellular membrane affinity chromatography columns for the study of human multidrug resistant proteins MRP1, MRP2 and human breast cancer resistant protein BCRP using membranes obtained from Spodoptera frugiperda (Sf9) Talanta, 2010, Jun-15, Volume: 81, Issue:4-5 Topics: Animals; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Cell Line; Cell Membrane; Chromatography; Etoposide; Humans; Inhibitory Concentration 50; Insecta; Kinetics; Ligands; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Stereoisomerism; Verapamil	2010
20(S)-ginsenoside Rh2 noncompetitively inhibits P-glycoprotein in vitro and in vivo: a case for herb-drug interactions. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caco-2 Cells; Digoxin; Etoposide; Ginsenosides; Herb-Drug Interactions; Humans; Ileum; Male; Rats; Rats, Sprague-Dawley; Rhodamine 123; Terfenadine; Verapamil	2010
Enhancing effect of N-octyl-O-sulfate chitosan on etoposide absorption. International journal of pharmaceutics, 2011, May-16, Volume: 409, Issue:1-2 Topics: Administration, Oral; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Caco-2 Cells; Chitosan; Etoposide; Excipients; Humans; Intestinal Absorption; Micelles; Rats; Rats, Sprague-Dawley; Solubility; Verapamil	2011
Enhanced intestinal absorption of etoposide by self-microemulsifying drug delivery systems: roles of P-glycoprotein and cytochrome P450 3A inhibition. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2013, Nov-20, Volume: 50, Issue:3-4 Topics: Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Availability; Caco-2 Cells; Cell Survival; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Delivery Systems; Etoposide; Humans; Intestinal Absorption; Ketoconazole; Male; Rats; Rats, Sprague-Dawley; Verapamil	2013
Characterization of a multiple endogenously expressed adenosine triphosphate-binding cassette transporters using nuclear and cellular membrane affinity chromatography columns. Journal of chromatography. A, 2014, Apr-25, Volume: 1339 Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Cell Line, Tumor; Cell Membrane; Chromatography, Affinity; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Estrone; Etoposide; Glioblastoma; Humans; Ligands; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Nuclear Envelope; Prazosin; Protein Binding; Verapamil	2014
Disruption of the association between drug transporter and actin cytoskeleton abolishes drug resistance in hypertrophic scar. Oncotarget, 2017, Jan-10, Volume: 8, Issue:2 Topics: Actin Cytoskeleton; Adolescent; Adult; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; Cicatrix, Hypertrophic; Drug Resistance; Etoposide; Female; Fibroblasts; Gene Expression Regulation; Humans; Male; Multidrug Resistance-Associated Proteins; Organophosphorus Compounds; Skin; Verapamil; Young Adult	2017
A role for ABCB1 in prognosis, invasion and drug resistance in ependymoma. Scientific reports, 2019, 07-16, Volume: 9, Issue:1 Topics: ATP Binding Cassette Transporter, Subfamily B; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Child, Preschool; Drug Resistance, Neoplasm; Drug Synergism; Ependymoma; Etoposide; Gene Expression Regulation, Neoplastic; Humans; Infant; Methotrexate; Neoplasm Invasiveness; Neoplastic Stem Cells; Prognosis; Survival Analysis; Up-Regulation; Vardenafil Dihydrochloride; Verapamil; Vincristine	2019