Page last updated: 2024-08-23

etoposide and trichostatin a

etoposide has been researched along with trichostatin a in 20 studies

Research

Studies (20)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (5.00)	18.2507
2000's	12 (60.00)	29.6817
2010's	7 (35.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Cai, W; Hao, Y; Hu, P; Ma, D; Pan, H; Xie, X; Yu, AD; Yu, J; Yuan, J; Zhang, L; Zhu, H	1
Hayakawa, S; Iida, A; Matsumoto, H; Tahara, T; Tomioka, K; Wada, SI; Yamashita, M	1
Austin, CA; Johnson, CA; Padget, K; Turner, BM	1
Kuusisto, E; Salminen, A; Suuronen, T	1
Guenther, MG; Kao, GD; Lazar, MA; McKenna, WG; Muschel, RJ; Yen, TJ	1
Baek, JH; Blake, M; Carrier, F; Kim, MS; Kohlhagen, G; Pommier, Y	1
Agostinho, M; Braga, J; Ferreira, F; Ferreira, J; Rino, J; Steffensen, S	1
Roemer, K; Wagner, S	1
Bader, P; Beck, JF; Hartwig, C; Heesch, S; Kumar, KS; Maass, M; Müller, C; Sonnemann, J	1
Bell, CW; Jiang, W; Pisetsky, DS; Reich, CF	1
Kang, MR; Kho, JH; Kim, EJ; Um, SJ	1
Hajji, N; Hermanson, O; Joseph, B; Nyman, U; Vlachos, P; Wallenborg, K	1
Chu, F; Davis, FB; Davis, PJ; Mousa, SA; Rebbaa, A	1
Füllgrabe, J; Hajji, N; Hermanson, O; Joseph, B; Vlachos, P; Wallenborg, K	1
Appel, B; Beck, JF; Beck, LF; Palani, CD; Sonnemann, J	1
Chen, GG; Lai, PB; Zhang, CZ; Zhang, HT	1
Jasek, E; Jasinska, M; Jurkowska, H; Lis, GJ; Litwin, JA	1
Choi, SH; Chung, WY; Jeong, JJ; Kang, SW; Lee, JM; Sung, TY	1
Fan, L; Jiang, T; Qiu, X; Yin, Y; Zhu, Q	1

Other Studies

20 other study(ies) available for etoposide and trichostatin a

Article	Year
Small molecule regulators of autophagy identified by an image-based high-throughput screen. Proceedings of the National Academy of Sciences of the United States of America, 2007, Nov-27, Volume: 104, Issue:48 Topics: Autophagy; Calcium Channel Blockers; Cell Line, Tumor; Drug Evaluation, Preclinical; Fluspirilene; Glioblastoma; Green Fluorescent Proteins; Humans; Intracellular Membranes; Loperamide; Microtubule-Associated Proteins; Mycotoxins; Peptides; Phagosomes; Phosphatidylinositol Phosphates; Pimozide; Protein Kinases; Recombinant Fusion Proteins; Sirolimus; Small Molecule Libraries; TOR Serine-Threonine Kinases; Trifluoperazine; Zinc Fingers	2007
Synthesis and biological evaluation of histone deacetylase and DNA topoisomerase II-Targeted inhibitors. Bioorganic & medicinal chemistry, 2018, 05-01, Volume: 26, Issue:8 Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; DNA Topoisomerases, Type II; HCT116 Cells; Histone Deacetylase 1; Histone Deacetylase 6; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; MCF-7 Cells; Recombinant Proteins; Structure-Activity Relationship; Topoisomerase II Inhibitors	2018
[Isolation of drug-resistant mutant cells]. Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 1991, Volume: 36, Issue:13 Topics: Alkylating Agents; Amphotericin B; Anti-Bacterial Agents; Antifungal Agents; Aphidicolin; Camptothecin; Cell Separation; Drug Resistance; Etoposide; Humans; Hydroxamic Acids; Lovastatin; Monensin; Nucleic Acids; Teniposide; Toxins, Biological; Tunicamycin	1991
Deacetylase activity associates with topoisomerase II and is necessary for etoposide-induced apoptosis. The Journal of biological chemistry, 2001, Feb-16, Volume: 276, Issue:7 Topics: Apoptosis; DNA Topoisomerases, Type II; Enzyme Inhibitors; Etoposide; HeLa Cells; Histone Deacetylase 1; Histone Deacetylase Inhibitors; Histone Deacetylases; HL-60 Cells; Humans; Hydroxamic Acids; Precipitin Tests; Two-Hybrid System Techniques	2001
Ubiquitin-binding protein p62 expression is induced during apoptosis and proteasomal inhibition in neuronal cells. Biochemical and biophysical research communications, 2001, Jan-12, Volume: 280, Issue:1 Topics: Animals; Apoptosis; Carrier Proteins; Cells, Cultured; Culture Media, Serum-Free; Cysteine Endopeptidases; Etoposide; Gene Expression Regulation; Hippocampus; Hydroxamic Acids; Immediate-Early Proteins; Mice; Multienzyme Complexes; Neuroblastoma; Neurons; Okadaic Acid; Proteasome Endopeptidase Complex; Rats; RNA, Messenger; Transcription Factor TFIIH; Transcription Factors; Transcription, Genetic; Tumor Cells, Cultured	2001
Histone deacetylase 4 interacts with 53BP1 to mediate the DNA damage response. The Journal of cell biology, 2003, Mar-31, Volume: 160, Issue:7 Topics: Carrier Proteins; Cell Line; Cell Nucleus; DNA Damage; DNA Repair; DNA-Binding Proteins; Dose-Response Relationship, Radiation; Etoposide; G2 Phase; Gamma Rays; Histone Deacetylases; Humans; Hydroxamic Acids; Intracellular Signaling Peptides and Proteins; Kinetics; Mutation; Nuclear Proteins; Nucleic Acid Synthesis Inhibitors; Phosphoproteins; Protein Synthesis Inhibitors; Repressor Proteins; RNA, Small Interfering; Tumor Cells, Cultured; Tumor Suppressor p53-Binding Protein 1	2003
Inhibition of histone deacetylase increases cytotoxicity to anticancer drugs targeting DNA. Cancer research, 2003, Nov-01, Volume: 63, Issue:21 Topics: Acetylation; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Line, Tumor; DNA Topoisomerases, Type II; DNA, Neoplasm; Drug Synergism; Enzyme Inhibitors; Etoposide; Gene Expression; Glioblastoma; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Tumor Suppressor Protein p53; Vorinostat	2003
Human topoisomerase IIalpha: targeting to subchromosomal sites of activity during interphase and mitosis. Molecular biology of the cell, 2004, Volume: 15, Issue:5 Topics: Antigens, Neoplasm; Autoantigens; Bromodeoxyuridine; Catalytic Domain; Cell Nucleus; Centromere Protein A; Centrosome; Chromosomal Proteins, Non-Histone; DNA Replication; DNA Topoisomerases, Type II; DNA-Binding Proteins; Etoposide; HeLa Cells; Heterochromatin; Histone Deacetylases; Humans; Hydroxamic Acids; Interphase; Intranuclear Space; Microscopy, Confocal; Microscopy, Fluorescence; Mitosis; Razoxane; RNA Polymerase II	2004
Retinoblastoma protein is required for efficient colorectal carcinoma cell apoptosis by histone deacetylase inhibitors in the absence of p21Waf. Biochemical pharmacology, 2005, Apr-01, Volume: 69, Issue:7 Topics: Adenocarcinoma; Apoptosis; Butyrates; Cell Cycle Proteins; Cell Line, Tumor; Colony-Forming Units Assay; Colorectal Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; DNA, Neoplasm; Doxorubicin; Enzyme Inhibitors; Etoposide; Flow Cytometry; Gene Deletion; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Kinetics; Retinoblastoma Protein; Transfection	2005
Histone deacetylase inhibitors induce cell death and enhance the susceptibility to ionizing radiation, etoposide, and TRAIL in medulloblastoma cells. International journal of oncology, 2006, Volume: 28, Issue:3 Topics: Acetylation; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Butyrates; Caspase 3; Caspase 9; Caspases; Cell Line, Tumor; DNA Fragmentation; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Synergism; Enzyme Activation; Enzyme Inhibitors; Etoposide; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; Medulloblastoma; Membrane Glycoproteins; Membrane Potentials; Mitochondrial Membranes; Radiation-Sensitizing Agents; Radiation, Ionizing; TNF-Related Apoptosis-Inducing Ligand; Tumor Necrosis Factor-alpha; Vincristine; Vorinostat	2006
The extracellular release of HMGB1 during apoptotic cell death. American journal of physiology. Cell physiology, 2006, Volume: 291, Issue:6 Topics: Amino Acid Chloromethyl Ketones; Antineoplastic Agents, Phytogenic; Apoptosis; Camptothecin; Cell Line; Cycloheximide; Cysteine Proteinase Inhibitors; Enzyme Inhibitors; Etoposide; HMGB1 Protein; Humans; Hydroxamic Acids; Protein Synthesis Inhibitors; Staurosporine; Tumor Necrosis Factor-alpha	2006
Active regulator of SIRT1 cooperates with SIRT1 and facilitates suppression of p53 activity. Molecular cell, 2007, Oct-26, Volume: 28, Issue:2 Topics: Acetylation; Amino Acid Sequence; Apoptosis; Base Sequence; Cell Nucleus; Cell Proliferation; Cell Survival; Cyclin-Dependent Kinase Inhibitor p21; DNA Damage; Down-Regulation; Enzyme Inhibitors; Etoposide; G1 Phase; HCT116 Cells; HeLa Cells; Humans; Hydroxamic Acids; Molecular Sequence Data; Mutation; Naphthalenes; Niacinamide; Nuclear Proteins; Pyrones; Resting Phase, Cell Cycle; RNA Interference; RNA, Small Interfering; Sirtuin 1; Sirtuins; Transcription Factors; Transcriptional Activation; Transfection; Tumor Suppressor Protein p53	2007
Combinatorial action of the HDAC inhibitor trichostatin A and etoposide induces caspase-mediated AIF-dependent apoptotic cell death in non-small cell lung carcinoma cells. Oncogene, 2008, May-15, Volume: 27, Issue:22 Topics: Amino Acid Chloromethyl Ketones; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Apoptosis Inducing Factor; bcl-2-Associated X Protein; bcl-X Protein; Carcinoma, Non-Small-Cell Lung; Caspase Inhibitors; Caspases; Drug Evaluation, Preclinical; Etoposide; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Lung Neoplasms; Models, Biological; RNA, Small Interfering; Signal Transduction; Tumor Cells, Cultured	2008
Novel function of the thyroid hormone analog tetraiodothyroacetic acid: a cancer chemosensitizing and anti-cancer agent. Angiogenesis, 2008, Volume: 11, Issue:3 Topics: Animals; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Cell Proliferation; Cisplatin; Doxorubicin; Drug Resistance, Neoplasm; Drug Synergism; Etoposide; Humans; Hydroxamic Acids; Mice; Mice, Nude; Neoplasms; Thyroid Hormones; Thyroxine; Tumor Cells, Cultured; Xenograft Model Antitumor Assays	2008
Opposing effects of hMOF and SIRT1 on H4K16 acetylation and the sensitivity to the topoisomerase II inhibitor etoposide. Oncogene, 2010, Apr-15, Volume: 29, Issue:15 Topics: Acetylation; Animals; Cell Death; Cell Line, Tumor; DNA Damage; Down-Regulation; Drug Resistance, Neoplasm; Enzyme Inhibitors; Etoposide; Histone Acetyltransferases; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; Lysine; Male; Neoplasms; Sirtuin 1; Topoisomerase II Inhibitors; Valproic Acid	2010
Serine proteases in histone deacetylase inhibitor-induced apoptosis. Molecular cancer therapeutics, 2010, Volume: 9, Issue:8 Topics: Apoptosis; Cell Line, Tumor; Etoposide; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Protease Inhibitors; Serine Endopeptidases; Sulfones; Vorinostat	2010
Trichostatin A sensitizes HBx-expressing liver cancer cells to etoposide treatment. Apoptosis : an international journal on programmed cell death, 2011, Volume: 16, Issue:7 Topics: BH3 Interacting Domain Death Agonist Protein; Caspases; Cell Death; Cell Nucleus; Drug Screening Assays, Antitumor; Enzyme Activation; Etoposide; Extracellular Signal-Regulated MAP Kinases; Green Fluorescent Proteins; Hep G2 Cells; Humans; Hydroxamic Acids; Liver Neoplasms; Phosphorylation; Protein Transport; Trans-Activators; Tumor Suppressor Protein p53; Viral Regulatory and Accessory Proteins	2011
Effect of histone deacetylase inhibitors trichostatin A and valproic acid on etoposide-induced apoptosis in leukemia cells. Anticancer research, 2012, Volume: 32, Issue:7 Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Caspase 3; Caspase 7; Drug Synergism; Etoposide; Histone Deacetylase Inhibitors; HL-60 Cells; Humans; Hydroxamic Acids; Leukemia; Membrane Potential, Mitochondrial; Proto-Oncogene Proteins c-bcl-2; RNA, Messenger; U937 Cells; Valproic Acid	2012
Innovative in vitro chemo-hormonal drug therapy for refractory thyroid carcinomas. Journal of Korean medical science, 2012, Volume: 27, Issue:7 Topics: Adenosine Triphosphate; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Etoposide; Humans; Hydroxamic Acids; Thyroid Neoplasms; Vincristine	2012
Targeting histones for degradation in cancer cells as a novel strategy in cancer treatment. Science China. Life sciences, 2019, Volume: 62, Issue:8 Topics: Acetylation; Animals; Antineoplastic Agents; Apoptosis; Camptothecin; Cell Cycle; Cell Line, Tumor; DNA Damage; Drug Therapy, Combination; Etoposide; Gamma Rays; Histone Deacetylase Inhibitors; Histones; Homeostasis; Humans; Hydroxamic Acids; Methyl Methanesulfonate; Mice; Valproic Acid; Vorinostat	2019