Page last updated: 2024-08-23

etoposide and tirapazamine

etoposide has been researched along with tirapazamine in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (25.00)18.2507
2000's8 (66.67)29.6817
2010's1 (8.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Guichard, M; Lartigau, E1
Brown, JM; Dorie, MJ1
Johnston, PJ; Olive, PL1
Inoue, A; Saijo, N1
Bloomer, WD; Ji, M; Papadopoulou, MV1
Brown, JM; Peters, KB1
Banáth, JP; Olive, PL1
Banáth, JP; Olive, PL; Sinnott, LT1
Crowley, JJ; Dakhil, SR; Edelman, MJ; Gandara, DR; Gaspar, LE; Le, QT; McCoy, J; Ryu, J; Sides, SD; Williamson, S1
Crowley, JJ; Gandara, DR; Gaspar, LE; Goldberg, Z; Lara, PN; Le, QT; Moon, J; Moore, DF; Redman, M; Williamson, SK1

Reviews

1 review(s) available for etoposide and tirapazamine

ArticleYear
Recent advances in the chemotherapy of non-small cell lung cancer.
    Japanese journal of clinical oncology, 2001, Volume: 31, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Non-Small-Cell Lung; Cisplatin; Deoxycytidine; Drug Administration Schedule; Etoposide; Gemcitabine; Humans; Irinotecan; Lung Neoplasms; Randomized Controlled Trials as Topic; Survival Rate; Tirapazamine; Triazines; Vinblastine; Vinorelbine

2001

Trials

2 trial(s) available for etoposide and tirapazamine

ArticleYear
Phase I study of tirapazamine plus cisplatin/etoposide and concurrent thoracic radiotherapy in limited-stage small cell lung cancer (S0004): a Southwest Oncology Group study.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Aug-15, Volume: 10, Issue:16

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Esophagitis; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neutropenia; Radiation-Sensitizing Agents; Radiotherapy Dosage; Tirapazamine; Triazines; Vomiting

2004
Phase II study of tirapazamine, cisplatin, and etoposide and concurrent thoracic radiotherapy for limited-stage small-cell lung cancer: SWOG 0222.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Jun-20, Volume: 27, Issue:18

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Esophagitis; Etoposide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neutropenia; Small Cell Lung Carcinoma; Survival Rate; Tirapazamine; Triazines

2009

Other Studies

9 other study(ies) available for etoposide and tirapazamine

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
The effect of tirapazamine (SR-4233) alone or combined with chemotherapeutic agents on xenografted human tumours.
    British journal of cancer, 1996, Volume: 73, Issue:12

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cell Division; Cisplatin; Dacarbazine; Drug Screening Assays, Antitumor; Etoposide; Fluorouracil; Humans; Melanoma; Mice; Mice, Nude; Rectal Neoplasms; Tirapazamine; Transplantation, Heterologous; Triazines

1996
Modification of the antitumor activity of chemotherapeutic drugs by the hypoxic cytotoxic agent tirapazamine.
    Cancer chemotherapy and pharmacology, 1997, Volume: 39, Issue:4

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Drug Interactions; Etoposide; Fluorouracil; Mice; Mice, Inbred C3H; Paclitaxel; Radiation-Sensitizing Agents; Tirapazamine; Triazines

1997
DNA damage from oxidants: influence of lesion complexity and chromatin organization.
    Oncology research, 1997, Volume: 9, Issue:6-7

    Topics: Animals; Antineoplastic Agents; Cell Death; Chromatin; Cricetinae; Cricetulus; DNA; DNA Damage; DNA, Single-Stranded; Doxorubicin; Etoposide; Fibroblasts; Mice; Oxidants; Tirapazamine; Triazines

1997
Schedule-dependent potentiation of chemotherapeutic drugs by the bioreductive compounds NLCQ-1 and tirapazamine against EMT6 tumors in mice.
    Cancer chemotherapy and pharmacology, 2001, Volume: 48, Issue:2

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Drug Synergism; Etoposide; Female; Fluorouracil; Imidazoles; Mammary Neoplasms, Experimental; Melphalan; Mice; Mice, Inbred BALB C; Paclitaxel; Quinolines; Tirapazamine; Triazines; Tumor Cells, Cultured

2001
Tirapazamine: a hypoxia-activated topoisomerase II poison.
    Cancer research, 2002, Sep-15, Volume: 62, Issue:18

    Topics: Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cell Hypoxia; DNA Damage; DNA Topoisomerases, Type II; DNA, Neoplasm; Enzyme Inhibitors; Etoposide; HeLa Cells; Humans; Lung Neoplasms; Tirapazamine; Topoisomerase II Inhibitors; Triazines

2002
Expression of phosphorylated histone H2AX as a surrogate of cell killing by drugs that create DNA double-strand breaks.
    Cancer research, 2003, Aug-01, Volume: 63, Issue:15

    Topics: 4-Nitroquinoline-1-oxide; Animals; Antineoplastic Agents; Bleomycin; Cell Death; Cell Line; Cricetinae; Cricetulus; DNA; DNA Damage; Doxorubicin; Etoposide; Fibroblasts; Histones; Hydrogen Peroxide; Phosphorylation; Tirapazamine; Triazines

2003
Phosphorylated histone H2AX in spheroids, tumors, and tissues of mice exposed to etoposide and 3-amino-1,2,4-benzotriazine-1,3-dioxide.
    Cancer research, 2004, Aug-01, Volume: 64, Issue:15

    Topics: Animals; Antineoplastic Agents; Cell Survival; DNA Damage; Etoposide; Female; Flow Cytometry; Histones; Humans; Hypoxia; Kidney; Mice; Mice, Inbred NOD; Mice, SCID; Phosphorylation; Spheroids, Cellular; Spleen; Tirapazamine; Transplantation, Heterologous; Triazines; Tumor Stem Cell Assay; Uterine Cervical Neoplasms

2004