Page last updated: 2024-08-23

etoposide and tipifarnib

etoposide has been researched along with tipifarnib in 6 studies

Research

Studies (6)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	4 (66.67)	29.6817
2010's	2 (33.33)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Smit, EF	1
Alsina, M; Beaupre, DM; Buzzeo, R; Dalton, WS; Enkemann, S; Lichtenheld, MG; Nimmanapalli, R	1
Adjei, AA; Dai, NT; Feldman, EJ; Flatten, K; Garrett-Mayer, E; Gore, SD; Greer, JM; Ironside, V; Karp, JE; Kaufmann, SH; Le, SB; Levis, MJ; Loegering, DA; Meng, XW; Morris, LE; Ricklis, RM; Ritchie, E; Roboz, G; Schneider, PA; Smith, BD; Talbott, T; Wright, JJ	1
Karp, J	1
Carraway, HE; Derecho, C; Feldman, EJ; Galkin, S; Garret-Mayer, E; Gocke, CD; Gore, SD; Greer, JM; Ironside, V; Karp, JE; Kaufmann, SH; Levis, MJ; Malek, S; McDevitt, MA; Morris, LE; Palma, J; Raponi, M; Ritchie, EK; Roboz, GR; Smith, BD; Vener, TI; Wang, Y; Wright, JJ	1
Christos, PJ; Feldman, EJ; Gergis, U; Mayer, S; Ritchie, EK; Roboz, GJ; Scandura, JM; Wissa, U	1

Trials

2 trial(s) available for etoposide and tipifarnib

Article	Year
Active oral regimen for elderly adults with newly diagnosed acute myelogenous leukemia: a preclinical and phase 1 trial of the farnesyltransferase inhibitor tipifarnib (R115777, Zarnestra) combined with etoposide. Blood, 2009, May-14, Volume: 113, Issue:20 Topics: Administration, Oral; Age of Onset; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Enzyme Inhibitors; Etoposide; Farnesyltranstransferase; HL-60 Cells; Humans; Jurkat Cells; Leukemia, Myeloid, Acute; Quinolones; Tumor Cells, Cultured; U937 Cells	2009
Multi-institutional phase 2 clinical and pharmacogenomic trial of tipifarnib plus etoposide for elderly adults with newly diagnosed acute myelogenous leukemia. Blood, 2012, Jan-05, Volume: 119, Issue:1 Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; DNA-Binding Proteins; Etoposide; Female; Follow-Up Studies; Guanine Nucleotide Exchange Factors; Humans; Leukemia, Myeloid, Acute; Male; Nuclear Proteins; Pharmacogenetics; Prognosis; Quinolones; Remission Induction; Retrospective Studies; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Survival Rate	2012

Article

Year

Active oral regimen for elderly adults with newly diagnosed acute myelogenous leukemia: a preclinical and phase 1 trial of the farnesyltransferase inhibitor tipifarnib (R115777, Zarnestra) combined with etoposide.

Blood, 2009, May-14, Volume: 113, Issue:20

Topics: Administration, Oral; Age of Onset; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Enzyme Inhibitors; Etoposide; Farnesyltranstransferase; HL-60 Cells; Humans; Jurkat Cells; Leukemia, Myeloid, Acute; Quinolones; Tumor Cells, Cultured; U937 Cells

2009

Multi-institutional phase 2 clinical and pharmacogenomic trial of tipifarnib plus etoposide for elderly adults with newly diagnosed acute myelogenous leukemia.

Blood, 2012, Jan-05, Volume: 119, Issue:1

Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; DNA-Binding Proteins; Etoposide; Female; Follow-Up Studies; Guanine Nucleotide Exchange Factors; Humans; Leukemia, Myeloid, Acute; Male; Nuclear Proteins; Pharmacogenetics; Prognosis; Quinolones; Remission Induction; Retrospective Studies; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Survival Rate

2012

Other Studies

4 other study(ies) available for etoposide and tipifarnib

Article	Year
[New data presented at ASCO 2002 concerning small cell bronchial cancer]. Revue de pneumologie clinique, 2002, Volume: 58, Issue:5 Pt 2 Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Carboplatin; Carcinoma, Small Cell; Cisplatin; Deoxycytidine; Etoposide; Gemcitabine; Humans; Imatinib Mesylate; Lung Neoplasms; Piperazines; Prognosis; Pyrimidines; Quinolones; Smoking; Smoking Prevention; Survival Analysis; Treatment Outcome	2002
Characterization of a R115777-resistant human multiple myeloma cell line with cross-resistance to PS-341. Clinical cancer research : an official journal of the American Association for Cancer Research, 2005, Aug-15, Volume: 11, Issue:16 Topics: Boronic Acids; Bortezomib; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Etoposide; Farnesyltranstransferase; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Heat-Shock Proteins; Humans; Melphalan; Multiple Myeloma; Oligonucleotide Array Sequence Analysis; Phenotype; Protease Inhibitors; Protein Prenylation; Pyrazines; Quinolones; ras Proteins; Staurosporine; Tunicamycin	2005
Future research directions for the treatment of AML. Clinical advances in hematology & oncology : H&O, 2008, Volume: 6, Issue:11 Topics: Antineoplastic Agents; Azacitidine; Biomedical Research; Carbazoles; Carboplatin; Cytarabine; Daunorubicin; Decitabine; Enzyme Inhibitors; Etoposide; Flavonoids; Furans; Humans; Leukemia, Myeloid, Acute; Mitoxantrone; Piperidines; Quinolones; Staurosporine; Topotecan; Tretinoin	2008
Are low-intensity induction strategies better for older patients with acute myeloid leukemia? Leukemia research, 2012, Volume: 36, Issue:4 Topics: Aged; Aged, 80 and over; Aminoglycosides; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Cytarabine; Daunorubicin; Etoposide; Female; Gemtuzumab; Humans; Induction Chemotherapy; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Male; Middle Aged; Oxides; Quinolones; Remission Induction; Retrospective Studies; Treatment Outcome	2012