etoposide has been researched along with thiazoles in 50 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 10 (20.00) | 18.2507 |
| 2000's | 26 (52.00) | 29.6817 |
| 2010's | 12 (24.00) | 24.3611 |
| 2020's | 2 (4.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hotta, T; Kawamoto, K; Kiya, K; Kurisu, K; Mikami, T; Nakada, Y; Saito, Y; Uozumi, T; Yamada, K | 1 |
| Endo, Y; Kimura, H; Kinoshita, K; Miyazaki, I; Ninomiya, I; Ohyama, S; Sasaki, T; Tanaka, M; Tugawa, K; Yonemura, Y | 1 |
| Fujita, H; Ishizaki, T; Itoh, R; Okada, H; Yamamoto, T; Yasuda, J | 1 |
| Gemba, K; Kiura, K; Matsumura, T; Moritaka, T; Ohnoshi, T; Segawa, Y; Shibayama, T; Tabata, M; Takigawa, N; Ueoka, H | 1 |
| Asaga, T; Kawahara, S; Osawa, Y; Yanoma, S; Yoshida, A | 1 |
| Fujimura, S; Kobayashi, S; Okada, S; Yoshida, H | 1 |
| Häcker, G; Roloff, S; Wilhelm, S | 1 |
| Borg, AG; Burgess, R; Fisher, A; Grey, M; Wood, P; Yin, JA | 1 |
| Fujita, M; Higashino, K; Tsuchida, T | 1 |
| Passaniti, A; Wang, W | 1 |
| Aikou, T; Akiyama, S; Furukawa, T; Ikeda, R; Kitazono, M; Nagayama, S; Okumura, H; Seto, K; Sumizawa, T | 1 |
| Goker, E; Karabulut, B; Omay, SB; Sanli, UA; Sezgin, C; Terzioglu, E; Uslu, R | 1 |
| Chao, Y; Chen, LT; Huang, TS; Shu, CH | 1 |
| Mahyar-Roemer, M; Roemer, K | 1 |
| Dixon, JE; Donner, DB; Durden, DL; Mayo, LD; Tonks, NK | 1 |
| Bassi, L; Carloni, M; Fonti, E; Meschini, R; Palitti, F; Palma de la Peña, N | 1 |
| Akeshima, R; Iba, T; Itamochi, H; Kamazawa, S; Kanamori, Y; Kigawa, J; Sultana, H; Terakawa, N | 1 |
| Deguchi, N; Murai, M; Nonaka, S; Ueno, M; Yamazaki, R | 1 |
| Creutzig, U; Hählen, K; Harbott, J; Huismans, DR; Kaspers, GJ; Pieters, R; Slater, RM; Veerman, AJ; Zimmermann, M; Zwaan, CM | 1 |
| Abe, A; Emi, N; Kanbe, E; Kawabe, T; Saito, H; Towatari, M | 1 |
| Chan, SL; Gilman, CP; Greig, N; Guo, Z; Mattson, MP; Zhu, X | 1 |
| Akaike, T; Fang, J; Greish, K; Maeda, H; Sawa, T | 1 |
| Gabbert, HE; Gerharz, CD; Reinecke, P; Schmitz, M; Steckstor, M | 1 |
| Bielawski, J; Dbaibo, GS; Gillanders, WE; Hannun, YA; Johnson, KR; Kozhaya, L; Obeid, LM; Osta, W; Taha, TA | 1 |
| Colakogullari, M; Ulukaya, E; Wood, EJ | 1 |
| Deveraux, QL; Engels, IH; Wagner, KW | 1 |
| Alaoui-Jamali, MA; Chow, TY; Griller, D; Yeh, C; Yuen, L | 1 |
| André, A; Braekman, JC; Bruyneel, F; Darro, F; Decaestecker, C; Dewelle, J; El Yazidi, M; Guissou, P; Kiss, R; Nacoulma, O; Simon, G; Tuti, J; Van Quaquebeke, E | 1 |
| Burlet, S; Dono, R; Garino, C; Kraus, JL; Laras, Y; Maina, F; Moumen, A; Pietrancosta, N; Quéléver, G | 1 |
| Faden, AI; Lea, PM; Movsesyan, VA | 1 |
| Parent, AD; Tamaki, N; Yin, D; Zhang, JH | 1 |
| Chang, KT; Chiu, CH; Huang, CY; Lok, YY; Tsai, CM | 1 |
| Shi, YP; We, QY; Wu, QX | 1 |
| Bähr, M; Dono, R; Kraus, JL; Lamballe, F; Lingor, P; Maina, F; Moumen, A; Pietrancosta, N; Planchamp, V | 1 |
| Lee, HJ; Lee, HK; Park, HT; Seo, IA; Suh, DJ | 1 |
| Mashima, T; Matsuura, M; Miyata, S; Okabe, S; Sato, S; Seimiya, H; Sugimoto, Y; Tsuruo, T | 1 |
| Arkin, MR; Byl, JA; Conroy, A; Fox, JA; Hawtin, RE; McDowell, RS; Nguyen, T; Osheroff, N; Stockett, DE; Yang, W | 1 |
| Kanomata, N; Kozuka, Y; Kurebayashi, J; Moriya, T; Sonoo, H; Watanabe, M | 1 |
| Kim, JH; Lee, WH; Suk, K; Zheng, LT | 1 |
| Akao, Y; Horiike, S; Kobayashi, S; Kobayashi, T; Kuroda, J; Matsumoto, Y; Nagoshi, H; Nishida, K; Sasaki, N; Shimura, Y; Taki, T; Taniwaki, M; Tsutsumi, Y; Yamamoto, M | 1 |
| Bai, W; Bepler, G; Dong, H; Khochbin, S; Nicosia, SV; Wang, L; Williams, KA; Xiang, S; Zhang, X | 1 |
| Evangelatov, A; Skrobanska, R; Yordanov, G | 1 |
| Li, QG; Tong, Y; Xia, Q; Xing, TY; Zhang, JJ; Zhang, M | 1 |
| Borchmann, P; Engert, A; Monsef, I; Rancea, M; Skoetz, N; Will, A | 1 |
| Chen, X; Dai, H; Qian, Z; Wang, Y; Xu, X; Zhao, Y | 1 |
| Bajrektarević, D; Filipič, M; Gajski, G; Garaj-Vrhovac, V; Gerić, M; Novak, M; Nunić, J; Žegura, B | 1 |
| Burdova, K; Lindqvist, A; Macurek, L; Müllers, E; Silva Cascales, H | 1 |
| Czaplinski, S; Fulda, S; Habermann, K; Hugle, M; Vogler, M | 1 |
| Gopas, J; Gopinath, P; Muraleedharan, KM; Nandakumar, N | 1 |
| Bakr, RB; El Azab, IH; Elkanzi, NAA | 1 |
50 other study(ies) available for etoposide and thiazoles
| Article | Year |
|---|---|
Glutathione and cellular response of ACNU-resistant rat glioma sublines to drugs and radiation.
Topics: Animals; Buthionine Sulfoximine; Cell Line; Cell Survival; Dose-Response Relationship, Radiation; Doxorubicin; Drug Resistance; Etoposide; Glioma; Glutathione; Kinetics; Methionine Sulfoximine; Nimustine; Pyrrolidonecarboxylic Acid; Rats; Thiazoles; Thiazolidines; Vinblastine | 1991 |
[Chemosensitivity test for gastric cancer by in vitro MTT assay].
Topics: Antineoplastic Agents; Carbazilquinone; Cisplatin; Doxorubicin; Drug Screening Assays, Antitumor; Etoposide; Fluorouracil; Humans; Mitomycin; Mitomycins; Stomach Neoplasms; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1991 |
[Estimation of medroxyprogesterone acetate (MPA) and etoposide against a human uterine endometrial cancer].
Topics: Animals; Cell Division; Drug Synergism; Endometrial Neoplasms; Etoposide; Female; Humans; Medroxyprogesterone Acetate; Mice; Mice, Nude; Subrenal Capsule Assay; Tetrazolium Salts; Thiazoles | 1994 |
[In vitro comparison of podophyllotoxin analogues; etoposide, teniposide and NK 611 using human lung cancer cell lines].
Topics: Adenocarcinoma; Antineoplastic Agents; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cell Division; Drug Resistance; Drug Screening Assays, Antitumor; Etoposide; Humans; Lung Neoplasms; Podophyllotoxin; Teniposide; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1993 |
[In vitro chemosensitivity test for seven undifferentiated thyroid carcinoma cell lines using MTT assay].
Topics: Antineoplastic Agents; Bleomycin; Carcinoma; Cisplatin; Cyclophosphamide; Dactinomycin; Doxorubicin; Drug Screening Assays, Antitumor; Etoposide; Humans; Methotrexate; Tetrazolium Salts; Thiazoles; Thyroid Neoplasms; Tumor Cells, Cultured; Vincristine | 1996 |
Indomethacin enhances the cytotoxicity of VCR and ADR in human pulmonary adenocarcinoma cells.
Topics: Adenocarcinoma; Adjuvants, Pharmaceutic; Coloring Agents; Doxorubicin; Drug Combinations; Drug Screening Assays, Antitumor; Etoposide; Humans; Indomethacin; Lung Neoplasms; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Vincristine | 1997 |
Inhibition of etoposide-induced apoptotic events by azide.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Azides; Coumarins; Etoposide; Flow Cytometry; Fluorescent Dyes; Humans; Jurkat Cells; Oligopeptides; Proto-Oncogene Proteins c-bcl-2; Tetrazolium Salts; Thiazoles; Ultraviolet Rays | 1997 |
Effect on cell kill of addition of multidrug resistance modifiers cyclosporin A and PSC 833 to cytotoxic agents in acute myeloid leukaemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cell Survival; Coloring Agents; Cyclosporine; Cyclosporins; Cytarabine; Daunorubicin; Drug Resistance, Neoplasm; Drug Synergism; Etoposide; Female; Humans; Idarubicin; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1997 |
Effect of vesnarinone in combination with anti-cancer drugs on lung cancer cell lines.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cell Division; Cisplatin; Coloring Agents; Deoxycytidine; DNA Fragmentation; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Etoposide; Flow Cytometry; Gemcitabine; Humans; Lung Neoplasms; Pyrazines; Quinolines; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1999 |
Extracellular matrix inhibits apoptosis and enhances endothelial cell differentiation by a NfkappaB-dependent mechanism.
Topics: Apoptosis; bcl-2-Associated X Protein; Cell Cycle; Cell Differentiation; Cell Line; Cell Nucleus; Cell Survival; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cytoplasm; DNA-Binding Proteins; Dose-Response Relationship, Drug; Endothelium, Vascular; Estradiol; Etoposide; Extracellular Matrix; Humans; I-kappa B Proteins; NF-kappa B; NF-KappaB Inhibitor alpha; Nucleic Acid Synthesis Inhibitors; Oligonucleotides, Antisense; Paclitaxel; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Receptors, Estrogen; Tetrazolium Salts; Thiazoles; Time Factors; Transfection | 1999 |
Reversal of LRP-associated drug resistance in colon carcinoma SW-620 cells.
Topics: Alkaloids; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Benzylisoquinolines; Butyrates; Carcinoma; Cell Nucleus; Colonic Neoplasms; Coloring Agents; Cyclic P-Oxides; Cytoplasm; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Neoplasm; Etoposide; Humans; Microscopy, Fluorescence; Neoplasm Proteins; Nicotinic Acids; RNA, Catalytic; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Cells, Cultured; Vault Ribonucleoprotein Particles | 2001 |
Arsenic trioxide-mediated cytotoxicity and apoptosis in prostate and ovarian carcinoma cell lines.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Apoptosis; Arsenic Trioxide; Arsenicals; Butylated Hydroxyanisole; Carcinogens; Cisplatin; DNA Fragmentation; Dose-Response Relationship, Drug; Doxorubicin; Enzyme-Linked Immunosorbent Assay; Etoposide; Female; Flow Cytometry; Humans; Male; Ovarian Neoplasms; Oxides; Prostatic Neoplasms; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2000 |
Evaluation of GL331 in combination with paclitaxel: GL331's interference with paclitaxel-induced cell cycle perturbation and apoptosis.
Topics: Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotting, Western; Calcium-Binding Proteins; Carrier Proteins; CDC2 Protein Kinase; Cell Cycle; Cell Cycle Proteins; Cell Nucleus; Cyclin B; Cyclin B1; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Antagonism; Drug Evaluation; Drug Interactions; Drug Therapy, Combination; Etoposide; Flow Cytometry; Fungal Proteins; Humans; Nasopharyngeal Neoplasms; Nuclear Proteins; Paclitaxel; Precipitin Tests; Protein Kinases; Tetrazolium Salts; Thiazoles; Toxicity Tests; Tumor Cells, Cultured | 2001 |
p21 Waf1/Cip1 can protect human colon carcinoma cells against p53-dependent and p53-independent apoptosis induced by natural chemopreventive and therapeutic agents.
Topics: Adenocarcinoma; Alleles; Amino Acid Chloromethyl Ketones; Anticarcinogenic Agents; Antineoplastic Agents; Apoptosis; Benzothiazoles; Butyrates; Cisplatin; Colonic Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cysteine Proteinase Inhibitors; Demecolcine; Doxorubicin; Drug Resistance, Neoplasm; Etoposide; Fluorouracil; Gene Expression Regulation, Neoplastic; Genes, p53; Humans; Intracellular Membranes; Membrane Potentials; Mitochondria; Neoplasm Proteins; Recombination, Genetic; Resveratrol; Stilbenes; Thiazoles; Toluene; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2001 |
PTEN protects p53 from Mdm2 and sensitizes cancer cells to chemotherapy.
Topics: Blotting, Western; Cell Cycle; Cell Line; Cell Nucleus; Cloning, Molecular; Coloring Agents; Cytoplasm; DNA Damage; Dose-Response Relationship, Drug; Down-Regulation; Etoposide; Genes, Reporter; Glioblastoma; Humans; Microscopy, Confocal; Mutation; Neoplasms; Nuclear Proteins; Phosphoric Monoester Hydrolases; Precipitin Tests; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-mdm2; PTEN Phosphohydrolase; Retroviridae; Signal Transduction; Tetrazolium Salts; Thiazoles; Transcription, Genetic; Transduction, Genetic; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Tumor Suppressor Proteins | 2002 |
Pifithrin-alpha, an inhibitor of p53, enhances the genetic instability induced by etoposide (VP16) in human lymphoblastoid cells treated in vitro.
Topics: Antineoplastic Agents, Phytogenic; Benzothiazoles; Cell Cycle; Cell Survival; Chromosome Aberrations; DNA Fragmentation; Dose-Response Relationship, Drug; Drug Synergism; Etoposide; Flow Cytometry; Humans; In Vitro Techniques; Karyotyping; Lymphocytes; Thiazoles; Time Factors; Toluene; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2002 |
Sensitivity to anticancer agents and resistance mechanisms in clear cell carcinoma of the ovary.
Topics: Adenocarcinoma, Clear Cell; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Camptothecin; Cisplatin; Coloring Agents; DNA Topoisomerases, Type I; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Etoposide; Female; Glutathione; Humans; Inhibitory Concentration 50; Irinotecan; Mitochondrial Proteins; Mitomycin; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Ovarian Neoplasms; Paclitaxel; Reverse Transcriptase Polymerase Chain Reaction; Ribosomal Proteins; RNA, Messenger; Saccharomyces cerevisiae Proteins; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2002 |
SN-38 induces cell cycle arrest and apoptosis in human testicular cancer.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Camptothecin; Cell Cycle; Cell Line; Cisplatin; DNA; Etoposide; G1 Phase; Humans; In Situ Nick-End Labeling; Irinotecan; Male; Testicular Neoplasms; Tetrazolium Salts; Thiazoles | 2002 |
Cellular drug resistance in childhood acute myeloid leukemia is related to chromosomal abnormalities.
Topics: Acute Disease; Adolescent; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Chromosome Aberrations; Chromosome Inversion; Chromosomes, Human; Cladribine; Cytarabine; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Etoposide; Female; Humans; Infant; Leukemia, Myeloid; Male; Neoplastic Stem Cells; Recurrence; Remission Induction; Tetrazolium Salts; Thiazoles; Translocation, Genetic; Trisomy | 2002 |
DR1-like element in human topoisomerase IIalpha gene involved in enhancement of etoposide-induced apoptosis by PPARgamma ligand.
Topics: Antigens, Neoplasm; Apoptosis; Chromans; DNA Topoisomerases, Type II; DNA-Binding Proteins; Electrophoretic Mobility Shift Assay; Etoposide; Flow Cytometry; Gene Expression; Humans; Jurkat Cells; Leukemia; Ligands; Mutagenesis; Phosphoproteins; Promoter Regions, Genetic; Prostaglandin D2; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Retinoid X Receptors; Thiazoles; Thiazolidinediones; Topoisomerase II Inhibitors; Transcription Factors; Transfection; Troglitazone; Tumor Cells, Cultured | 2003 |
p53 is present in synapses where it mediates mitochondrial dysfunction and synaptic degeneration in response to DNA damage, and oxidative and excitotoxic insults.
Topics: Animals; Benzothiazoles; Brain; Cells, Cultured; DNA Damage; Etoposide; Membrane Potentials; Mice; Mitochondria; Neurodegenerative Diseases; Neuroprotective Agents; Neurotoxins; Nucleic Acid Synthesis Inhibitors; Oxidative Stress; Phosphorylation; Presynaptic Terminals; Reactive Oxygen Species; Synapsins; Synaptosomes; Thiazoles; Toluene; Tumor Suppressor Protein p53 | 2003 |
Enhancement of chemotherapeutic response of tumor cells by a heme oxygenase inhibitor, pegylated zinc protoporphyrin.
Topics: Animals; Annexin A5; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Body Weight; Camptothecin; Cell Line, Tumor; Cisplatin; Coloring Agents; Dose-Response Relationship, Drug; Doxorubicin; Drug Synergism; Etoposide; Heme Oxygenase (Decyclizing); Humans; Hydrogen Peroxide; Male; Metalloporphyrins; Mice; Mitomycin; Neoplasms; Oxidants; Oxidation-Reduction; Oxidative Stress; Oxygen; Polyethylene Glycols; Proline; Reactive Oxygen Species; Tetrazolium Salts; Thiazoles | 2004 |
Chemotherapeutic potential of plant alkaloids and multidrug resistance mechanisms in malignant fibrous histiocytoma of the heart.
Topics: Alkaloids; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Cell Separation; Cell Survival; Cells, Cultured; Coloring Agents; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Etoposide; Flow Cytometry; Heart Neoplasms; Histiocytoma, Benign Fibrous; Humans; Inhibitory Concentration 50; Paclitaxel; Phenotype; Plant Extracts; Soft Tissue Neoplasms; Tetrazolium Salts; Thiazoles; Vault Ribonucleoprotein Particles; Vincristine | 2004 |
Down-regulation of sphingosine kinase-1 by DNA damage: dependence on proteases and p53.
Topics: Apoptosis; Blotting, Western; Cell Division; Cell Line, Tumor; Cell Survival; Coloring Agents; Dactinomycin; DNA Damage; Dose-Response Relationship, Drug; Down-Regulation; Doxorubicin; Endopeptidases; Enzyme Inhibitors; Etoposide; Gamma Rays; Humans; Mass Spectrometry; Models, Biological; Phosphotransferases (Alcohol Group Acceptor); Proto-Oncogene Proteins c-bcl-2; Reverse Transcriptase Polymerase Chain Reaction; RNA Processing, Post-Transcriptional; RNA, Messenger; RNA, Small Interfering; Tetrazolium Salts; Thiazoles; Transcription, Genetic; Tumor Suppressor Protein p53; Up-Regulation | 2004 |
Interference by anti-cancer chemotherapeutic agents in the MTT-tumor chemosensitivity assay.
Topics: Antineoplastic Agents; Cisplatin; Colorimetry; Drug Interactions; Drug Screening Assays, Antitumor; Etoposide; Tetrazolium Salts; Thiazoles | 2004 |
Caspase-2 can function upstream of bid cleavage in the TRAIL apoptosis pathway.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; bcl-2-Associated X Protein; BH3 Interacting Domain Death Agonist Protein; Blotting, Western; Carrier Proteins; Caspase 2; Caspase 3; Caspase 7; Caspase 8; Caspases; Cell Death; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Activation; Etoposide; Gene Silencing; Humans; Membrane Glycoproteins; Mitochondria; Models, Biological; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; RNA Interference; RNA, Small Interfering; Staurosporine; Tetrazolium Salts; Thiazoles; Time Factors; TNF-Related Apoptosis-Inducing Ligand; Transfection; Tumor Necrosis Factor-alpha | 2004 |
The DNA double-stranded break repair protein endo-exonuclease as a therapeutic target for cancer.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Carcinoma, Lewis Lung; Cell Line, Tumor; Cell Survival; Cisplatin; Coloring Agents; DNA; DNA Damage; DNA Repair; Down-Regulation; Drug Evaluation, Preclinical; Endonucleases; Etoposide; Exonucleases; Fluorouracil; HeLa Cells; Humans; Kinetics; Mice; Mitomycin; Neoplasms; Pentamidine; Plasmids; Recombination, Genetic; RNA, Small Interfering; Tetrazolium Salts; Thiazoles; Time Factors | 2004 |
Identification of a novel cardenolide (2''-oxovoruscharin) from Calotropis procera and the hemisynthesis of novel derivatives displaying potent in vitro antitumor activities and high in vivo tolerance: structure-activity relationship analyses.
Topics: Animals; Antineoplastic Agents; Calotropis; Camptothecin; Cardenolides; Cell Line, Tumor; Cell Proliferation; Cerebral Cortex; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Etoposide; Humans; Irinotecan; Magnetic Resonance Spectroscopy; Maximum Tolerated Dose; Mice; Organoplatinum Compounds; Oxaliplatin; Paclitaxel; Sodium-Potassium-Exchanging ATPase; Structure-Activity Relationship; Swine; Thiazoles | 2005 |
Novel cyclized Pifithrin-alpha p53 inactivators: synthesis and biological studies.
Topics: Animals; Benzothiazoles; Cerebral Cortex; Drug Stability; Etoposide; Mice; Models, Chemical; Molecular Structure; Neurons; Structure-Activity Relationship; Thiazoles; Toluene; Tumor Suppressor Protein p53 | 2005 |
Neuroprotective activity of the mGluR5 antagonists MPEP and MTEP against acute excitotoxicity differs and does not reflect actions at mGluR5 receptors.
Topics: Animals; Apoptosis; Cell Survival; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Dose-Response Relationship, Drug; Etoposide; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Glycine; Hydrolysis; Male; Membrane Potentials; Mice; Mice, Knockout; N-Methylaspartate; Neurons; Neuroprotective Agents; Phenylacetates; Phosphatidylinositols; Pyridines; Rats; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Thiazoles | 2005 |
Insulin-like growth factor-I decreased etoposide-induced apoptosis in glioma cells by increasing bcl-2 expression and decreasing CPP32 activity.
Topics: Apoptosis; Benzimidazoles; Blotting, Southern; Blotting, Western; Caspase 3; Caspases; Cell Count; Cell Line, Tumor; Cell Proliferation; Colorimetry; Cyclin D1; DNA Fragmentation; Dose-Response Relationship, Drug; Drug Interactions; Endopeptidases; Etoposide; Gene Expression Regulation, Neoplastic; Glioma; Humans; Insulin-Like Growth Factor I; Nerve Tissue Proteins; Nucleic Acid Synthesis Inhibitors; Oligodeoxyribonucleotides, Antisense; Receptor, IGF Type 1; Tetrazolium Salts; Thiazoles; Time Factors; Transfection | 2005 |
Role of IL-6 in neuroendocrine differentiation and chemosensitivity of non-small cell lung cancer.
Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung; Cell Count; Cell Differentiation; Cell Division; Cell Line, Tumor; Cisplatin; Coloring Agents; Down-Regulation; ErbB Receptors; Etoposide; Humans; Interleukin-6; Lung Neoplasms; Neurosecretory Systems; Phosphopyruvate Hydratase; Receptors, Interleukin-6; Recombinant Proteins; Signal Transduction; Tetrazolium Salts; Thiazoles | 2005 |
Sesquiterpenes with various carbon skeletons from Ligularia virgaurea spp. oligocephala.
Topics: Antineoplastic Agents, Phytogenic; Asteraceae; Cell Line, Tumor; Etoposide; HL-60 Cells; Humans; Indicators and Reagents; Magnetic Resonance Spectroscopy; Plant Extracts; Sesquiterpenes; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Infrared; Spectroscopy, Fourier Transform Infrared; Tetrazolium Salts; Thiazoles | 2006 |
Imino-tetrahydro-benzothiazole derivatives as p53 inhibitors: discovery of a highly potent in vivo inhibitor and its action mechanism.
Topics: Administration, Topical; Animals; Antineoplastic Agents; Apoptosis; Axotomy; Benzothiazoles; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p21; Drug Design; Drug Stability; Etoposide; Imines; Male; Mice; Neocortex; Neuroprotective Agents; Optic Nerve; Phosphorylation; Prodrugs; Rats; Rats, Wistar; Retinal Ganglion Cells; Thiazoles; Toluene; Tumor Suppressor Protein p53; Vitreous Body | 2006 |
A novel mechanism of methylglyoxal cytotoxicity in neuroglial cells.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Survival; Cells, Cultured; Cytokine Receptor gp130; Dose-Response Relationship, Drug; Etoposide; Flow Cytometry; Hydrogen Peroxide; Interleukin-6; Neuroglia; Protein Binding; Protein Processing, Post-Translational; Protein Transport; Pyruvaldehyde; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Signal Transduction; STAT3 Transcription Factor; Tetrazolium Salts; Thiazoles; Time Factors; Transfection | 2009 |
Acyl-CoA synthetase as a cancer survival factor: its inhibition enhances the efficacy of etoposide.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Benzimidazoles; Caspases; Catalysis; Cell Line, Tumor; Cell Survival; Coenzyme A Ligases; Cytochrome c Group; Dose-Response Relationship, Drug; Etoposide; Fluorescent Antibody Technique; Fluorescent Dyes; Glioma; Humans; Indoles; Injections, Subcutaneous; Isoenzymes; Mice; Mice, Nude; Neoplasm Transplantation; Subcellular Fractions; Tetrazolium Salts; Thiazoles; Triazenes; Tumor Burden; Xenograft Model Antitumor Assays | 2009 |
Voreloxin is an anticancer quinolone derivative that intercalates DNA and poisons topoisomerase II.
Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; DNA; DNA Damage; DNA Fragmentation; DNA Topoisomerases, Type II; Drug Delivery Systems; Etoposide; G2 Phase; Humans; Intercalating Agents; Naphthyridines; Quinolones; Thiazoles | 2010 |
Preferential antitumor effect of the Src inhibitor dasatinib associated with a decreased proportion of aldehyde dehydrogenase 1-positive cells in breast cancer cells of the basal B subtype.
Topics: Aldehyde Dehydrogenase; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Dasatinib; DNA Damage; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Etoposide; Humans; Inhibitory Concentration 50; Neoplastic Stem Cells; Pyrimidines; src-Family Kinases; Thiazoles | 2010 |
Pro-apoptotic role of integrin β3 in glioma cells.
Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Carmustine; Cell Line, Tumor; Drug Interactions; Enzyme Inhibitors; Etoposide; Flow Cytometry; Free Radical Scavengers; Gene Expression Regulation, Neoplastic; Glioma; Humans; Integrin beta3; Nitric Oxide; Rats; RNA, Messenger; Signal Transduction; Statistics as Topic; Tetrazolium Salts; Thiazoles; Vitronectin | 2011 |
Bcl-2 is a better therapeutic target than c-Myc, but attacking both could be a more effective treatment strategy for B-cell lymphoma with concurrent Bcl-2 and c-Myc overexpression.
Topics: Aniline Compounds; Antineoplastic Agents; Blotting, Western; Cell Line, Tumor; Cell Survival; Chromosomes, Human, Pair 14; Chromosomes, Human, Pair 18; Cytarabine; Dose-Response Relationship, Drug; Doxorubicin; Drug Synergism; Etoposide; Gene Expression Regulation, Neoplastic; Humans; Lymphoma, Large B-Cell, Diffuse; MicroRNAs; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-myc; Reverse Transcriptase Polymerase Chain Reaction; Spectral Karyotyping; Sulfonamides; Thiazoles; Translocation, Genetic | 2011 |
Depletion of HDAC6 enhances cisplatin-induced DNA damage and apoptosis in non-small cell lung cancer cells.
Topics: Animals; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cell Line, Tumor; Cisplatin; Comet Assay; DNA Damage; Doxorubicin; Etoposide; Female; Histone Deacetylase 6; Histone Deacetylases; Humans; Immunoblotting; Immunohistochemistry; Inhibitory Concentration 50; Lung Neoplasms; Mice; Mice, Nude; Neoplasm Transplantation; Tetrazolium Salts; Thiazoles | 2012 |
Colloidal formulations of etoposide based on poly(butyl cyanoacrylate) nanoparticles: preparation, physicochemical properties and cytotoxicity.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Benzimidazoles; Cell Line, Tumor; Chemistry, Pharmaceutical; Colloids; Coloring Agents; Enbucrilate; Etoposide; Fluorescent Dyes; Humans; Indicators and Reagents; Light; Microscopy, Electron, Scanning; Nanoparticles; Particle Size; Scattering, Radiation; Tetrazolium Salts; Thiazoles | 2013 |
HIF1 regulates WSB-1 expression to promote hypoxia-induced chemoresistance in hepatocellular carcinoma cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Hepatocellular; Carrier Proteins; Cell Hypoxia; DNA Damage; Drug Resistance, Neoplasm; Etoposide; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Intracellular Signaling Peptides and Proteins; Liver Neoplasms; Promoter Regions, Genetic; Protein Serine-Threonine Kinases; Proteins; RNA Interference; RNA, Small Interfering; Tetrazolium Salts; Thiazoles | 2013 |
Fifteenth biannual report of the Cochrane Haematological Malignancies Group--focus on non-Hodgkin's lymphoma.
Topics: Adult; Aged; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Bleomycin; Cyclophosphamide; Dasatinib; Doxorubicin; Etoposide; Hodgkin Disease; Humans; Imatinib Mesylate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Lymphoma, Non-Hodgkin; Middle Aged; Multicenter Studies as Topic; Multiple Myeloma; Neoplasm Staging; Piperazines; Platelet Transfusion; Prednisone; Primary Prevention; Procarbazine; Pyrimidines; Randomized Controlled Trials as Topic; Rituximab; Stem Cell Transplantation; Survival Analysis; Thiazoles; Thrombocytopenia; Transplantation, Autologous; Treatment Outcome; Vincristine; Vindesine | 2013 |
In vitro chemosensitivity assay of ascites in epithelial ovarian cancer.
Topics: Antineoplastic Agents; Ascites; Carboplatin; Carcinoma, Ovarian Epithelial; Coloring Agents; Deoxycytidine; Disease Progression; Drug Screening Assays, Antitumor; Epirubicin; Etoposide; Female; Fluorouracil; Gemcitabine; Humans; Kaplan-Meier Estimate; Ki-67 Antigen; Middle Aged; Neoplasms, Glandular and Epithelial; Ovarian Neoplasms; Paclitaxel; Predictive Value of Tests; Retrospective Studies; Survival Rate; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2013 |
Genotoxic potential of selected cytostatic drugs in human and zebrafish cells.
Topics: Acridine Orange; Animals; Cell Line; Cell Survival; Cisplatin; Cytostatic Agents; Ethidium; Etoposide; Fluorouracil; Hep G2 Cells; Humans; Lymphocytes; Tetrazolium Salts; Thiazoles; Zebrafish | 2016 |
Residual Cdk1/2 activity after DNA damage promotes senescence.
Topics: Antigens, CD; Cadherins; CDC2 Protein Kinase; Cell Line; Cell Line, Tumor; Cell Size; Cell Survival; Cellular Senescence; Cyclin B1; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase Inhibitor p21; DNA Damage; Epithelial Cells; Etoposide; G2 Phase Cell Cycle Checkpoints; Gene Expression Regulation; Humans; Osteoblasts; Pteridines; Purines; Quinolines; Retinal Pigment Epithelium; Signal Transduction; Single-Cell Analysis; Thiazoles | 2017 |
Identification of Smac mimetics as novel substrates for p-glycoprotein.
Topics: Apoptosis Regulatory Proteins; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biomimetic Materials; Cell Line, Tumor; Dipeptides; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Etoposide; Humans; Indoles; Inhibitor of Apoptosis Proteins; Intracellular Signaling Peptides and Proteins; Mitochondrial Proteins; Neuroblastoma; Oligopeptides; Rhabdomyosarcoma; Thiazoles; Up-Regulation; Vincristine | 2019 |
Benzisothiazolone Derivatives Exhibit Cytotoxicity in Hodgkin's Lymphoma Cells through NF-κB Inhibition and are Synergistic with Doxorubicin and Etoposide.
Topics: A549 Cells; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Movement; Doxorubicin; Drug Synergism; Etoposide; Hodgkin Disease; Humans; NF-kappa B; Thiazoles | 2020 |
Facile One-Pot Multicomponent Synthesis of Pyrazolo-Thiazole Substituted Pyridines with Potential Anti-Proliferative Activity: Synthesis, In Vitro and In Silico Studies.
Topics: Antineoplastic Agents; Cell Line, Tumor; Chemistry Techniques, Synthetic; Computer Simulation; DNA Topoisomerases, Type II; Drug Screening Assays, Antitumor; Etoposide; HeLa Cells; Humans; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Docking Simulation; PC-3 Cells; Pyrazoles; Pyridines; Spectrophotometry, Infrared; Thiazoles | 2021 |