Page last updated: 2024-08-23

etoposide and thapsigargin

etoposide has been researched along with thapsigargin in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (26.09)18.2507
2000's12 (52.17)29.6817
2010's5 (21.74)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Cai, W; Hao, Y; Hu, P; Ma, D; Pan, H; Xie, X; Yu, AD; Yu, J; Yuan, J; Zhang, L; Zhu, H1
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J1
Aridoss, G; Bleeker, NP; Hermanson, DL; Xing, C; Zhou, B1
Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P1
Cohen, GM; Dinsdale, D; Fearnhead, HO1
Akiyama, Y; Bessho, R; Furusho, K; Kataoka, A; Kubota, M; Lin, YW; Okuda, A; Usami, I; Wakazono, Y1
Kaneko, Y; Tsukamoto, A1
Bello, BD; Comporti, M; Maellaro, E1
Chow, SC; Cohen, GM; Orrenius, S; Snowden, R1
Barone, R; Colussi, C; Coppola, S; Fanelli, C; Ghibelli, L; Gualandi, G; Volpe, P1
Bleackley, RC; Bossy-Wetzel, E; Burns, K; Fadel, MP; Goping, IS; Green, DR; Lozyk, M; Michalak, M; Nakamura, K; Opas, M1
Briehl, MM; Tome, ME1
Berger, SA; Zhang, Y1
de Léséleuc, L; Denis, F1
Concannon, CG; Gorman, AM; Ní Chonghaile, T; Samali, A; Szegezdi, E1
Berchtold, CM; Huang, TT; Miyamoto, S; Wu, ZH1
Choi, YH; Kim, SH; Kwon, TK; Lee, JT; Lee, TJ; Park, JW; Song, KS1
Kepp, O; Kroemer, G; Martins, I; Métivier, D; Michaud, M; Perfettini, JL; Schlemmer, F; Senovilla, L; Séror, C; Tesniere, A; Zitvogel, L1
Cheng, EH; Hsieh, JJ; Jeffers, JR; Kim, H; Ren, D; Takeuchi, O; Tu, HC; Zambetti, GP1
Harford, TJ; Shaltouki, A; Weyman, CM1
Hendershot, LM; Liao, N; Mann, MJ; Pereira, ER1
Becker, S; Brodde, M; Burkhardt, R; Ceglarek, U; Christoffersen, C; Feuerborn, R; Nagel, P; Nofer, JR; Potì, F; Schmidt, H1

Other Studies

23 other study(ies) available for etoposide and thapsigargin

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Small molecule regulators of autophagy identified by an image-based high-throughput screen.
    Proceedings of the National Academy of Sciences of the United States of America, 2007, Nov-27, Volume: 104, Issue:48

    Topics: Autophagy; Calcium Channel Blockers; Cell Line, Tumor; Drug Evaluation, Preclinical; Fluspirilene; Glioblastoma; Green Fluorescent Proteins; Humans; Intracellular Membranes; Loperamide; Microtubule-Associated Proteins; Mycotoxins; Peptides; Phagosomes; Phosphatidylinositol Phosphates; Pimozide; Protein Kinases; Recombinant Fusion Proteins; Sirolimus; Small Molecule Libraries; TOR Serine-Threonine Kinases; Trifluoperazine; Zinc Fingers

2007
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
    Nature chemical biology, 2009, Volume: 5, Issue:10

    Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection

2009
Structure-activity relationship (SAR) study of ethyl 2-amino-6-(3,5-dimethoxyphenyl)-4-(2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate (CXL017) and the potential of the lead against multidrug resistance in cancer treatment.
    Journal of medicinal chemistry, 2012, Jun-14, Volume: 55, Issue:11

    Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzopyrans; Cell Line, Tumor; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Proto-Oncogene Proteins c-bcl-2; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Structure-Activity Relationship

2012
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
    Bioorganic & medicinal chemistry, 2012, Nov-15, Volume: 20, Issue:22

    Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship

2012
An interleukin-1 beta-converting enzyme-like protease is a common mediator of apoptosis in thymocytes.
    FEBS letters, 1995, Nov-20, Volume: 375, Issue:3

    Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Caspase 1; Cells, Cultured; Cysteine Endopeptidases; Dexamethasone; DNA; Etoposide; Flow Cytometry; Kinetics; Male; Poly(ADP-ribose) Polymerases; Protease Inhibitors; Rats; Rats, Inbred F344; Terpenes; Thapsigargin; Thymus Gland

1995
Selection and partial characterization of calcium ionophore (A23187) resistant cells.
    Biochemical and biophysical research communications, 1995, Aug-15, Volume: 213, Issue:2

    Topics: Antineoplastic Agents; Apoptosis; Calcimycin; Calcium; Cell Division; Cytarabine; DNA; Drug Resistance; Etoposide; Flow Cytometry; Humans; Ionomycin; Leukemia, Promyelocytic, Acute; Terpenes; Thapsigargin; Tumor Cells, Cultured; Ultraviolet Rays

1995
Apoptosis and nuclear levels of p53 protein and proliferating cell nuclear antigen in human hepatoma cells cultured with tumor promoters.
    Cancer letters, 1995, May-04, Volume: 91, Issue:1

    Topics: Apoptosis; Carcinogens; Carcinoma, Hepatocellular; DNA Damage; Etoposide; Flow Cytometry; Humans; Lyngbya Toxins; Mitomycin; Proliferating Cell Nuclear Antigen; Terpenes; Thapsigargin; Tumor Cells, Cultured; Tumor Suppressor Protein p53

1995
Protection by ascorbate against apoptosis of thymocytes: implications of ascorbate-induced nonlethal oxidative stress and poly(ADP-ribosyl)ation.
    Experimental cell research, 1996, Jul-10, Volume: 226, Issue:1

    Topics: Animals; Apoptosis; Ascorbic Acid; Dehydroascorbic Acid; DNA; Enzyme Inhibitors; Etoposide; Free Radicals; Hydrogen Peroxide; Male; Methylprednisolone; NAD; Neuroprotective Agents; Oxidative Stress; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Rats; Rats, Sprague-Dawley; Terpenes; Thapsigargin; Thymus Gland

1996
Susceptibility of different subsets of immature thymocytes to apoptosis.
    FEBS letters, 1997, May-19, Volume: 408, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Apoptosis; CD3 Complex; CD4 Antigens; CD8 Antigens; Cell Survival; Cells, Cultured; Dexamethasone; DNA; Enzyme Inhibitors; Etoposide; Flow Cytometry; Male; Rats; Rats, Inbred F344; T-Lymphocyte Subsets; Thapsigargin; Thymus Gland

1997
Magnetic fields increase cell survival by inhibiting apoptosis via modulation of Ca2+ influx.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1999, Volume: 13, Issue:1

    Topics: Animals; Apoptosis; Calcium; Cell Line; Cell Survival; Electromagnetic Fields; Enzyme Inhibitors; Etoposide; Humans; Ionomycin; Rats; Thapsigargin; Thymus Gland; Topoisomerase II Inhibitors; U937 Cells

1999
Changes in endoplasmic reticulum luminal environment affect cell sensitivity to apoptosis.
    The Journal of cell biology, 2000, Aug-21, Volume: 150, Issue:4

    Topics: Animals; Apoptosis; Calcium; Calcium-Binding Proteins; Calnexin; Calreticulin; Cell Line; Cloning, Molecular; Cytochrome c Group; Dogs; Endoplasmic Reticulum; Etoposide; HeLa Cells; Humans; Membrane Proteins; Mice; Mitochondria; Molecular Chaperones; Rabbits; Ribonucleoproteins; Staurosporine; T-Lymphocytes; Thapsigargin; Ultraviolet Rays

2000
Thymocytes selected for resistance to hydrogen peroxide show altered antioxidant enzyme profiles and resistance to dexamethasone-induced apoptosis.
    Cell death and differentiation, 2001, Volume: 8, Issue:9

    Topics: Animals; Antioxidants; Apoptosis; Catalase; Cell Division; Cytochrome c Group; Cytosol; Dexamethasone; Drug Resistance; Etoposide; Glutathione Transferase; Hydrogen Peroxide; Mice; Paraquat; Protein Transport; Proto-Oncogene Proteins c-bcl-2; Staurosporine; Superoxide Dismutase; Thapsigargin; Thymus Gland; Tumor Cells, Cultured

2001
Increased calcium influx and ribosomal content correlate with resistance to endoplasmic reticulum stress-induced cell death in mutant leukemia cell lines.
    The Journal of biological chemistry, 2004, Feb-20, Volume: 279, Issue:8

    Topics: Anti-Bacterial Agents; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Area Under Curve; Calcium; Cell Death; Cell Line, Tumor; Cycloheximide; Dithiothreitol; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Neoplasm; Econazole; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Etoposide; Fas Ligand Protein; Flow Cytometry; HL-60 Cells; Humans; Leukemia; Membrane Glycoproteins; Oligonucleotide Array Sequence Analysis; Phenotype; Ribosomes; Thapsigargin; Time Factors; Tunicamycin

2004
Inhibition of apoptosis by Nur77 through NF-kappaB activity modulation.
    Cell death and differentiation, 2006, Volume: 13, Issue:2

    Topics: Apoptosis; Apoptosis Regulatory Proteins; Camptothecin; Cell Line; Cycloheximide; DNA Damage; DNA-Binding Proteins; Endoplasmic Reticulum; Etoposide; Fas Ligand Protein; Fibroblasts; Gene Expression Regulation; Humans; Inhibitor of Apoptosis Proteins; Membrane Glycoproteins; NF-kappa B; Nuclear Receptor Subfamily 4, Group A, Member 1; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Thapsigargin; Transcription Factors; Transfection; Tumor Necrosis Factors

2006
Dexamethasone inhibits apoptosis in C6 glioma cells through increased expression of Bcl-XL.
    Apoptosis : an international journal on programmed cell death, 2006, Volume: 11, Issue:7

    Topics: Animals; Antineoplastic Agents, Hormonal; Apoptosis; bcl-X Protein; Blotting, Northern; Blotting, Western; Caspase 3; Caspase 9; Caspases; Cell Line, Tumor; Cytochromes c; Dexamethasone; Enzyme Activation; Etoposide; Gene Expression; Mifepristone; Receptors, Glucocorticoid; RNA, Messenger; RNA, Small Interfering; Staurosporine; Thapsigargin

2006
Calcium-dependent regulation of NEMO nuclear export in response to genotoxic stimuli.
    Molecular and cellular biology, 2007, Volume: 27, Issue:2

    Topics: Active Transport, Cell Nucleus; Animals; Calcium Signaling; Camptothecin; Cell Line; Cell Nucleus; Chelating Agents; DNA Damage; Egtazic Acid; Enzyme Activation; Etoposide; Guanine Nucleotide Exchange Factors; Humans; I-kappa B Kinase; Ionomycin; Ionophores; NF-kappa B; Protein Binding; Protein Structure, Tertiary; Thapsigargin

2007
Overexpression of Par-4 enhances thapsigargin-induced apoptosis via down-regulation of XIAP and inactivation of Akt in human renal cancer cells.
    Journal of cellular biochemistry, 2008, Feb-01, Volume: 103, Issue:2

    Topics: Adenocarcinoma, Clear Cell; Amino Acid Chloromethyl Ketones; Apoptosis; Apoptosis Regulatory Proteins; Caspases; Cell Division; Cell Line, Tumor; Endoplasmic Reticulum; Enzyme Activation; Etoposide; Gene Expression Regulation, Neoplastic; Humans; Kidney Neoplasms; Phosphorylation; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Recombinant Fusion Proteins; Thapsigargin; TNF-Related Apoptosis-Inducing Ligand; Transfection; X-Linked Inhibitor of Apoptosis Protein

2008
Chemotherapy induces ATP release from tumor cells.
    Cell cycle (Georgetown, Tex.), 2009, Nov-15, Volume: 8, Issue:22

    Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; Apoptosis; Cadmium; Cell Line, Tumor; Cisplatin; Etoposide; Flow Cytometry; Fluorescent Antibody Technique; Mice; Mitomycin; Mitoxantrone; Neoplasms; Organoplatinum Compounds; Oxaliplatin; Sphingosine; Thapsigargin

2009
Stepwise activation of BAX and BAK by tBID, BIM, and PUMA initiates mitochondrial apoptosis.
    Molecular cell, 2009, Nov-13, Volume: 36, Issue:3

    Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; Bcl-2-Like Protein 11; BH3 Interacting Domain Death Agonist Protein; Cells, Cultured; Etoposide; Fibroblasts; Green Fluorescent Proteins; Immunoblotting; Immunoprecipitation; Membrane Proteins; Mice; Mice, Knockout; Microscopy, Fluorescence; Mitochondria; Models, Biological; Mutation; Protein Binding; Protein Multimerization; Proto-Oncogene Proteins; Staurosporine; Thapsigargin; Tumor Suppressor Proteins; Tunicamycin

2009
Increased expression of the pro-apoptotic Bcl2 family member PUMA and apoptosis by the muscle regulatory transcription factor MyoD in response to a variety of stimuli.
    Apoptosis : an international journal on programmed cell death, 2010, Volume: 15, Issue:1

    Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Cell Line; Estrogens; Etoposide; Fibroblasts; Gene Expression; Mice; Myoblasts, Skeletal; MyoD Protein; Thapsigargin; Tumor Suppressor Proteins

2010
UPR-induced resistance to etoposide is downstream of PERK and independent of changes in topoisomerase IIα levels.
    PloS one, 2012, Volume: 7, Issue:10

    Topics: Activating Transcription Factor 4; Activating Transcription Factor 6; Animals; Antigens, Neoplasm; Blotting, Western; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Survival; Cells, Cultured; DNA Topoisomerases, Type II; DNA-Binding Proteins; Drug Resistance; eIF-2 Kinase; Embryo, Mammalian; Endoribonucleases; Etoposide; Fibroblasts; HEK293 Cells; Humans; Mice; Mice, Knockout; NIH 3T3 Cells; Protein Serine-Threonine Kinases; Regulatory Factor X Transcription Factors; Reverse Transcriptase Polymerase Chain Reaction; Thapsigargin; Topoisomerase II Inhibitors; Transcription Factors; Unfolded Protein Response; X-Box Binding Protein 1

2012
High density lipoprotein (HDL)-associated sphingosine 1-phosphate (S1P) inhibits macrophage apoptosis by stimulating STAT3 activity and survivin expression.
    Atherosclerosis, 2017, Volume: 257

    Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Cytoprotection; Dose-Response Relationship, Drug; Endoplasmic Reticulum Stress; Etoposide; Inhibitor of Apoptosis Proteins; Janus Kinase 2; Lipoproteins, HDL; Lysophospholipids; Macrophages; Mice; Mitochondria; RAW 264.7 Cells; Repressor Proteins; Signal Transduction; Sphingosine; STAT3 Transcription Factor; Survivin; Thapsigargin; Time Factors

2017