etoposide has been researched along with temozolomide in 65 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (1.54) | 18.2507 |
2000's | 20 (30.77) | 29.6817 |
2010's | 40 (61.54) | 24.3611 |
2020's | 4 (6.15) | 2.80 |
Authors | Studies |
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Lombardo, F; Obach, RS; Waters, NJ | 1 |
Choo, HY; Jung, MJ; Kim, MH; Kwon, Y; Lim, SY; Rhee, HK | 1 |
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
Benfenati, E; Raska, I; Toropov, AA; Toropova, AP | 1 |
Glen, RC; Lowe, R; Mitchell, JB | 1 |
Ekins, S; Williams, AJ; Xu, JJ | 1 |
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
Cancemi, G; Cascioferro, S; Daidone, G; Grimaudo, S; Maggio, B; Plescia, F; Raffa, D; Raimondi, MV; Tolomeo, M | 1 |
Cho, H; Elkamhawy, A; Heo, JC; Kim, HY; Kim, KH; Lee, CO; Nam, DH; Pae, AN; Park, WK; Roh, EJ; Seol, HJ; Viswanath, AN; Yang, H | 1 |
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
Liu, Y; Xu, Z; Zhao, SJ | 1 |
Benincasa, E; Bonmassar, E; D'Atri, S; Graziani, G; Jiricny, J; Lacal, PM; Pagani, E; Tentori, L; Zambruno, G | 1 |
Newton, HB; Santi, M; Stevens, C | 1 |
Lichtman, SM; Skirvin, JA | 1 |
Ebert, BL; Niemierko, E; Salgia, R; Shaffer, K | 1 |
Benita-Weiss, M; Bushunow, P; Coyle, TE; Evans, B; Friedman, H; Korones, DN; Mechtler, L; Quinn, JA; Reardon, DA | 1 |
Bourg, V; Chanalet, S; Chatel, M; Fontaine, D; Frenay, M; Lebrun, C; Lonjon, M; Michiels, JF; Paquis, P; Ramaioli, A; Vandenbos, F | 1 |
Castellano, A; Cozza, R; De Laurentis, C; De Sio, L; Deb, G; Dominici, C; Donfrancesco, A; Fidani, P; Ilari, I; Inserra, A; Jenkner, A; Milano, GM | 1 |
Bouffet, E; Foreman, N; Korones, DN; Smith, A | 1 |
Addo-Yobo, SO; Donson, AM; Foreman, NK; Gore, L; Handler, MH | 1 |
Bajciova, V; Kadlecova, V; Kepak, T; Mazanek, P; Mudry, P; Pavelka, Z; Sterba, J; Valik, D; Zitterbart, K | 1 |
Berger, MS; Katayama, M; Kawaguchi, T; Pieper, RO | 1 |
Fangusaro, J; Finlay, J; Rook, J; Rosser, T | 1 |
Chen, ZP; Mu, YG; Sai, K; Shi, HL; Yue, WY; Zhang, JP; Zhang, XH | 1 |
Bouffet, E; Fukushima, S; Katsuki, H; Shigemori, M; Terasaki, M | 1 |
Ashley, DM; Dobrovic, A; Drummond, KJ; Friedman, HS; Gan, HK; Hawkins, CJ; Johns, TG; Kaye, AH; Lovric, MM; Maxwell, JA; Mikeska, T; Riffkin, CD | 1 |
Fujii, M; Ito, M; Natsume, A; Ohno, M; Wakabayashi, T | 1 |
Darzynkiewicz, Z; Kurose, A; Ogasawara, K; Ogawa, A; Sato, Y; Sawai, T; Traganos, F | 1 |
Fukushima, T; Inoue, T; Komatsu, F; Ohmura, T; Ohta, M; Oshiro, S; Sakamoto, S; Tsugu, H | 1 |
Pappo, A; Paulino, AC | 1 |
Attinà, G; Bertolini, P; Colosimo, C; Lazzareschi, I; Mastrangelo, S; Maurizi, P; Migliorati, R; Pastore, M; Riccardi, R; Rizzo, D; Ruggiero, A | 1 |
Cawkwell, L; Little, SJ; Maraveyas, A; Murray, A; Stanley, P | 1 |
Desjardins, A; Friedman, AH; Friedman, HS; Gururangan, S; Herndon, JE; Marcello, J; McLendon, R; Peters, K; Reardon, DA; Rich, JN; Sampson, J; Threatt, S; Vredenburgh, JJ | 1 |
Anson, J; Gollard, RP; Khoury, J; Mason, J; Rosen, L | 1 |
Busch, C; Knappskog, S; Oberg, K; Sebjornsen, S; Sorbye, H; Welin, S | 1 |
Bangert, A; Cristofanon, S; Debatin, KM; Fulda, S; Häcker, S | 1 |
Boström, J; Glas, M; Herrlinger, U; Kim, Y; Mack, F; Rieger, J; Schäfer, N; Scheffler, B; Simon, M; Steinbach, JP; Stuplich, M; Thanendrarajan, S; Tichy, J | 1 |
Craig, EA; Spiegelman, VS | 1 |
Desjardins, A; Sampson, JH | 1 |
Behler, CM; Cha, S; Damon, LE; Hwang, J; Issa, S; McDermott, M; O'Brien, J; Rubenstein, JL; Shuman, MA; Treseler, P; Valles, F; Wieduwilt, MJ | 1 |
André, N; Bajciova, V; Deak, L; Demlova, R; Doubek, M; Dubska, L; Husek, K; Kepak, T; Kutnikova, L; Kyr, M; Martincekova, A; Mazanek, P; Mudry, P; Pavelka, Z; Skotakova, J; Sterba, J; Valik, D; Zapletalova, D; Zitterbart, K | 1 |
Escalon, E; Melnick, SJ; Nair, SM; Ramachandran, C | 1 |
Basu, EM; Cheung, NK; Kramer, K; Kushner, BH; Modak, S; Roberts, SS | 1 |
Anderluh, G; Assunção, Fdos S; Biasoli, D; de Souza, JM; Frauches, AC; Garcia, C; Geraldo, LH; Kahn, SA; Lima, FR; Moura-Neto, V; Pontes, B; Romão, L; Sobrinho, M; Soletti, RC; Tovar-Moll, F | 1 |
Bauer, D; Biassoni, V; Casanova, M; Catania, S; De Pava, MV; Gandola, L; Indini, A; Massimino, M; Modena, P; Pecori, E; Podda, M; Polastri, D; Rampini, P; Schiavello, E | 1 |
Attinà, G; Bertolini, P; Colosimo, C; Lazzareschi, I; Mastrangelo, S; Maurizi, P; Migliorati, R; Riccardi, R; Ridola, V; Rizzo, D; Ruggiero, A | 1 |
Arakawa, Y; Fujimoto, K; Kikuchi, T; Kunieda, T; Miyamoto, S; Mizowaki, T; Murata, D; Takagi, Y; Takahashi, JC | 1 |
Cesano, A; Conroy, A; Cordeiro, JA; Fields, SZ; Hawtin, RE; Leung, LY; Louie, B; Rosen, DB; Shapira, I | 1 |
Escalon, E; Lollett, IV; Melnick, SJ; Quirin, KW; Ramachandran, C | 1 |
Baudin, E; Caplin, ME; Ferolla, P; Filosso, P; Garcia-Yuste, M; Lim, E; Oberg, K; Pelosi, G; Perren, A; Rossi, RE; Travis, WD | 1 |
Chang, FC; Chang, KP; Chen, HH; Chen, YW; Guo, WY; Ho, DM; Hu, YW; Lai, IC; Lee, YY; Liang, ML; Shiau, CY; Wong, TT; Yen, SH | 1 |
Elhag, R; Mazzio, EA; Soliman, KF | 1 |
Engert, F; Fulda, S; Probst, M; Schneider, C; Weiβ, LM | 1 |
Kondo, T; Miyamoto, M; Ohta, T; Watanabe, T; Yamamoto, Y; Yamasaki, H | 1 |
de Stanchina, E; Desmeules, P; Gardner, EE; Lok, BH; Ni, A; Poirier, JT; Powell, SN; Rekhtman, N; Riaz, N; Rudin, CM; Schneeberger, VE; Teicher, BA | 1 |
Kobos, R; LaQuaglia, MP; Modak, S; Pandit-Taskar, N; Sait, S | 1 |
Ceylan, S; Gokturk, D; Kelebek, H; Yilmaz, DM | 1 |
Bison, B; Bojko, S; Gielen, GH; Hoffmann, M; Kortmann, RD; Kramm, CM; Pietsch, T; Seidel, C; von Bueren, AO; Warmuth-Metz, M | 1 |
Choi, DK; DiPatri, AJ; Lulla, RR; Marzec, S; Pillay-Smiley, N; Tomita, T; Wadhwani, NR | 1 |
Ahmed, EM; Bandopadhyay, G; Coyle, B; Grabowska, A | 1 |
Nazha, B; Owonikoko, TK | 1 |
Adachi, S; Akazawa, R; Arakawa, Y; Hiramatsu, H; Kato, I; Moritake, H; Okamoto, T; Saida, S; Sakamoto, A; Sumiyoshi, S; Takita, J; Umeda, K | 1 |
Halfdanarson, TR; Leventakos, K; Molina, JR; Uprety, D | 1 |
Berruti, A; Carminati, O; Cosentini, D; Ferrari, VD; Grisanti, S; Laganà, M; Rosti, G; Sigala, S; Turla, A | 1 |
Adachi, S; Hiramatsu, H; Kato, I; Mizowaki, T; Nakamoto, Y; Okamoto, T; Saida, S; Sakamoto, A; Shimizu, H; Takita, J; Taura, K; Umeda, K; Uto, M | 1 |
6 review(s) available for etoposide and temozolomide
Article | Year |
---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
1,2,3-Triazole-containing hybrids as potential anticancer agents: Current developments, action mechanisms and structure-activity relationships.
Topics: Antineoplastic Agents; Humans; Molecular Structure; Neoplasms; Structure-Activity Relationship; Triazoles | 2019 |
Pharmacokinetic considerations of oral chemotherapy in elderly patients with cancer.
Topics: Administration, Oral; Aged; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Complementary Therapies; Cytochrome P-450 Enzyme System; Dacarbazine; Etoposide; Humans; Idarubicin; Neoplasms; Tamoxifen; Temozolomide; Thalidomide; Topotecan | 2002 |
Pulmonary neuroendocrine (carcinoid) tumors: European Neuroendocrine Tumor Society expert consensus and recommendations for best practice for typical and atypical pulmonary carcinoids.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bronchoscopy; Carboplatin; Carcinoid Heart Disease; Carcinoid Tumor; Cisplatin; Dacarbazine; Etoposide; Europe; Humans; Lung Neoplasms; Pneumonectomy; Positron-Emission Tomography; Receptors, Somatostatin; Societies, Medical; Temozolomide; Tomography, X-Ray Computed; Ultrasonography | 2015 |
Primary Central Nervous System Malignant Melanoma in Children: A Case Series and Review of the Literature.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Chemoradiotherapy; Child, Preschool; Etoposide; Humans; Ipilimumab; Male; Melanoma; Temozolomide | 2018 |
Pulmonary Neuroendocrine Tumors: Adjuvant and Systemic Treatments.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bronchial Neoplasms; Capecitabine; Carcinoid Tumor; Chemotherapy, Adjuvant; Cisplatin; Etoposide; Everolimus; Humans; Immune Checkpoint Inhibitors; Lung Neoplasms; Lymph Node Excision; Molecular Targeted Therapy; Neuroendocrine Tumors; Octreotide; Organometallic Compounds; Pneumonectomy; Protein Kinase Inhibitors; Radiopharmaceuticals; Receptors, Somatostatin; Somatostatin; Temozolomide; Watchful Waiting | 2020 |
8 trial(s) available for etoposide and temozolomide
Article | Year |
---|---|
Phase I study of temozolomide and escalating doses of oral etoposide for adults with recurrent malignant glioma.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dacarbazine; Dose-Response Relationship, Drug; Etoposide; Female; Glioma; Humans; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Recurrence, Local; Survival Rate; Temozolomide; Treatment Outcome | 2003 |
Ifosfamide/carboplatin/etoposide (ICE) as front-line, topotecan/cyclophosphamide as second-line and oral temozolomide as third-line treatment for advanced neuroblastoma over one year of age.
Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Child; Child, Preschool; Cyclophosphamide; Dacarbazine; Drug Resistance, Neoplasm; Etoposide; Female; Humans; Ifosfamide; Infant; Male; Neoplasm Recurrence, Local; Neuroblastoma; Palliative Care; Temozolomide; Topotecan; Treatment Outcome | 2004 |
Combined biodifferentiating and antiangiogenic oral metronomic therapy is feasible and effective in relapsed solid tumors in children: single-center pilot study.
Topics: Administration, Oral; Adolescent; Adult; Angiogenesis Inhibitors; Antineoplastic Combined Chemotherapy Protocols; Celecoxib; Child; Child, Preschool; Dacarbazine; Drug Administration Schedule; Etoposide; Feasibility Studies; Female; Humans; Male; Neoplasm Recurrence, Local; Neoplasms; Pilot Projects; Pyrazoles; Sulfonamides; Temozolomide; Treatment Outcome; Tretinoin | 2006 |
Pilot trial of the rate of response, safety, and tolerability of temozolomide and oral VP-16 in patients with recurrent or treatment-induced malignant central nervous system tumors.
Topics: Administration, Oral; Adolescent; Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Drug Therapy, Combination; Etoposide; Female; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasms, Neuroepithelial; Neoplasms, Second Primary; Pilot Projects; Temozolomide; Treatment Outcome | 2008 |
Phase I study of temozolomide combined with oral etoposide in children with recurrent or progressive medulloblastoma.
Topics: Administration, Oral; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Cerebellar Neoplasms; Child; Dacarbazine; Etoposide; Female; Humans; Magnetic Resonance Imaging; Male; Maximum Tolerated Dose; Medulloblastoma; Neoplasm Recurrence, Local; Temozolomide; Treatment Outcome | 2010 |
Phase II study of metronomic chemotherapy with bevacizumab for recurrent glioblastoma after progression on bevacizumab therapy.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Dacarbazine; Disease-Free Survival; Etoposide; Female; Glioblastoma; Humans; Kaplan-Meier Estimate; Karnofsky Performance Status; Male; Middle Aged; Neoplasm Recurrence, Local; Temozolomide | 2011 |
Immunochemotherapy with intensive consolidation for primary CNS lymphoma: a pilot study and prognostic assessment by diffusion-weighted MRI.
Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Brain; Central Nervous System Neoplasms; Consolidation Chemotherapy; Cytarabine; Dacarbazine; Diffusion Magnetic Resonance Imaging; Etoposide; Female; Humans; Immunotherapy; Lymphoma; Male; Methotrexate; Middle Aged; Prognosis; Remission Induction; Rituximab; Survival Analysis; Temozolomide; Treatment Outcome | 2012 |
Phase I study of temozolomide combined with oral etoposide in children with malignant glial tumors.
Topics: Administration, Oral; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Child; Child, Preschool; Dacarbazine; Drug Resistance, Neoplasm; Etoposide; Female; Follow-Up Studies; Glioma; Humans; Male; Maximum Tolerated Dose; Neoplasm Recurrence, Local; Neoplasm Staging; Prognosis; Prospective Studies; Salvage Therapy; Temozolomide | 2013 |
51 other study(ies) available for etoposide and temozolomide
Article | Year |
---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Synthesis of isoquinolinone-based tetracycles as poly (ADP-ribose) polymerase-1 (PARP-1) inhibitors.
Topics: Antineoplastic Agents; Cell Line, Tumor; DNA Damage; Enzyme Inhibitors; Heterocyclic Compounds, 4 or More Rings; Humans; Isoquinolines; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Quinolones | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
QSPR modeling of octanol/water partition coefficient of antineoplastic agents by balance of correlations.
Topics: Antineoplastic Agents; Models, Chemical; Octanols; Quantitative Structure-Activity Relationship; Water | 2010 |
Predicting phospholipidosis using machine learning.
Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Synthesis and antiproliferative activity of 3-(2-chloroethyl)-5-methyl-6-phenyl-8-(trifluoromethyl)-5,6-dihydropyrazolo[3,4-f][1,2,3,5]tetrazepin-4-(3H)-one.
Topics: Antineoplastic Agents; Apoptosis; Azepines; Cell Cycle; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; HL-60 Cells; Humans; K562 Cells; Molecular Structure; Pyrazoles; Structure-Activity Relationship | 2015 |
Discovery of potent and selective cytotoxic activity of new quinazoline-ureas against TMZ-resistant glioblastoma multiforme (GBM).
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Dacarbazine; Dose-Response Relationship, Drug; Drug Discovery; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Glioblastoma; Humans; Models, Molecular; Molecular Conformation; Quinazolines; Structure-Activity Relationship; Temozolomide; Urea | 2015 |
Involvement of the mismatch repair system in temozolomide-induced apoptosis.
Topics: Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Cycle; Cell Division; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Dacarbazine; DNA Repair; Etoposide; Humans; Nucleic Acid Heteroduplexes; Temozolomide; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 1998 |
Brain metastases from fallopian tube carcinoma responsive to intra-arterial carboplatin and intravenous etoposide: a case report.
Topics: Adenocarcinoma, Papillary; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Brain Stem; Carboplatin; Carotid Arteries; Cisplatin; Combined Modality Therapy; Cranial Irradiation; Cyclophosphamide; Dacarbazine; Etoposide; Fallopian Tube Neoplasms; Fallopian Tubes; Female; Humans; Infusions, Intra-Arterial; Infusions, Intravenous; Magnetic Resonance Imaging; Middle Aged; Paclitaxel; Physical Examination; Rupture, Spontaneous; Temozolomide; Temporal Lobe; Vertebral Artery | 2001 |
Use of temozolomide with other cytotoxic chemotherapy in the treatment of patients with recurrent brain metastases from lung cancer.
Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Combined Modality Therapy; Dacarbazine; Etoposide; Female; Humans; Lung Neoplasms; Middle Aged; Prognosis; Temozolomide; Treatment Outcome | 2003 |
Long-term outcome of oligodendrogliomas.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Brain Neoplasms; Cisplatin; Combined Modality Therapy; Cranial Irradiation; Craniotomy; Dacarbazine; Epilepsies, Partial; Etoposide; Female; Follow-Up Studies; Humans; Life Tables; Lomustine; Magnetic Resonance Imaging; Male; Middle Aged; Neoadjuvant Therapy; Nitrosourea Compounds; Oligodendroglioma; Organophosphorus Compounds; Procarbazine; Prognosis; Proportional Hazards Models; Radionuclide Imaging; Radiopharmaceuticals; Survival Analysis; Technetium Tc 99m Sestamibi; Temozolomide; Treatment Outcome; Vincristine | 2004 |
Temozolomide and oral VP-16 for children and young adults with recurrent or treatment-induced malignant gliomas.
Topics: Administration, Oral; Adolescent; Adult; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Dacarbazine; Etoposide; Female; Glioma; Humans; Male; Neoplasm Recurrence, Local; Neoplasms, Second Primary; Retrospective Studies; Survival Analysis; Temozolomide; Treatment Outcome | 2006 |
MGMT promoter methylation correlates with survival benefit and sensitivity to temozolomide in pediatric glioblastoma.
Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Line, Tumor; Child; Child, Preschool; Dacarbazine; DNA Methylation; DNA Modification Methylases; DNA Repair Enzymes; DNA, Neoplasm; Drug Resistance, Neoplasm; Etoposide; Gene Silencing; Glioblastoma; Humans; Kaplan-Meier Estimate; Neoplasm Proteins; Retrospective Studies; Temozolomide; Treatment Outcome; Tumor Suppressor Proteins | 2007 |
DNA damaging agent-induced autophagy produces a cytoprotective adenosine triphosphate surge in malignant glioma cells.
Topics: Adenosine Triphosphate; Antineoplastic Agents, Alkylating; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Cell Death; Cell Line, Tumor; Dacarbazine; DNA Damage; Etoposide; Glioma; Humans; Membrane Proteins; Oxidation-Reduction; Phosphorylation; Temozolomide | 2007 |
Acute transient encephalopathy following paclitaxel treatment in an adolescent with a recurrent suprasellar germinoma.
Topics: Adolescent; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Brain Diseases; Carboplatin; Cerebral Ventricle Neoplasms; Combined Modality Therapy; Consciousness Disorders; Cranial Irradiation; Cyclophosphamide; Cytarabine; Dacarbazine; Deoxycytidine; Etoposide; Female; Gemcitabine; Germinoma; Hematopoietic Stem Cell Transplantation; Humans; Hypophysectomy; Neoplasm Recurrence, Local; Organoplatinum Compounds; Oxaliplatin; Paclitaxel; Pituitary Neoplasms; Temozolomide; Thiotepa; Topotecan | 2008 |
[Individualized chemotherapy based on drug sensitivity and resistance assay and MGMT protein expression for patients with malignant glioma--analysis of 42 cases].
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Child; Cisplatin; Dacarbazine; Drug Resistance, Neoplasm; Etoposide; Female; Gene Expression Regulation, Neoplastic; Glioblastoma; Glioma; Humans; Male; Middle Aged; Nausea; Neutropenia; O(6)-Methylguanine-DNA Methyltransferase; Remission Induction; Temozolomide; Young Adult | 2006 |
In vitro sensitivity testing of minimally passaged and uncultured gliomas with TRAIL and/or chemotherapy drugs.
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Astrocytes; Carboplatin; Cell Line, Tumor; Cisplatin; Dacarbazine; Drug Screening Assays, Antitumor; Etoposide; Female; Glioblastoma; Glioma; Hepatocytes; Humans; Lomustine; Male; Membrane Glycoproteins; Middle Aged; Procarbazine; Recombinant Fusion Proteins; Temozolomide; TNF-Related Apoptosis-Inducing Ligand; Tumor Necrosis Factor-alpha; Vincristine | 2008 |
Interferon-beta, MCNU, and conventional radiotherapy for pediatric patients with brainstem glioma.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Brain Stem Neoplasms; Carboplatin; Child; Child, Preschool; Dacarbazine; Disease-Free Survival; DNA Methylation; Etoposide; Female; Glioma; Humans; Interferon-beta; Magnetic Resonance Imaging; Male; Nitrosourea Compounds; Retrospective Studies; Temozolomide; Treatment Outcome | 2009 |
Diversity of DNA damage response of astrocytes and glioblastoma cell lines with various p53 status to treatment with etoposide and temozolomide.
Topics: Antineoplastic Agents; Apoptosis; Astrocytes; beta-Galactosidase; Cell Cycle; Cell Line, Tumor; Cells, Cultured; Cellular Senescence; Cyclin-Dependent Kinase Inhibitor p16; Cyclin-Dependent Kinase Inhibitor p21; Dacarbazine; DNA Damage; Etoposide; Flow Cytometry; Fluorescent Antibody Technique; Glioblastoma; Histones; Humans; Immunohistochemistry; Mutation; O(6)-Methylguanine-DNA Methyltransferase; Phosphorylation; Temozolomide; Time Factors; Tumor Suppressor Protein p53 | 2009 |
Efficacy of temozolomide treatment in patients with high-grade glioma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboplatin; Chemotherapy, Adjuvant; Combined Modality Therapy; Dacarbazine; Etoposide; Female; Glioblastoma; Gliosarcoma; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Oligodendroglioma; Prognosis; Temozolomide; Treatment Outcome; Tumor Necrosis Factor-alpha | 2009 |
Alveolar rhabdomyosarcoma of the extremity and nodal metastasis: Is the in-transit lymphatic system at risk?
Topics: Antineoplastic Combined Chemotherapy Protocols; Benzenesulfonates; Camptothecin; Child; Combined Modality Therapy; Cyclophosphamide; Dacarbazine; Dactinomycin; Etoposide; Fatal Outcome; Female; Foot; Groin; Humans; Ifosfamide; Irinotecan; Lymph Node Excision; Lymphatic Metastasis; Lymphatic System; Male; Niacinamide; Phenylurea Compounds; Pyridines; Radiotherapy, Adjuvant; Radiotherapy, High-Energy; Rhabdomyosarcoma, Alveolar; Salvage Therapy; Soft Tissue Neoplasms; Sorafenib; Temozolomide; Thigh; Vincristine | 2009 |
Sorafenib enhances the in vitro anti-endothelial effects of low dose (metronomic) chemotherapy.
Topics: Angiogenesis Inhibitors; Antineoplastic Combined Chemotherapy Protocols; Benzenesulfonates; Cell Line, Tumor; Cell Proliferation; Dacarbazine; Drug Administration Schedule; Endothelial Cells; Etoposide; Humans; In Vitro Techniques; Neovascularization, Pathologic; Niacinamide; Paclitaxel; Phenylurea Compounds; Pyridines; Sorafenib; Temozolomide | 2010 |
Intramedullary PNET of the spine: long-term survival after combined modality therapy and subsequent relapse.
Topics: Antineoplastic Combined Chemotherapy Protocols; Busulfan; Cerebellar Neoplasms; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Dacarbazine; Etoposide; Female; Humans; Methylprednisolone Hemisuccinate; Neuroectodermal Tumors, Primitive; Neuroprotective Agents; Radiotherapy; Spinal Neoplasms; Temozolomide; Thiotepa; Thoracic Vertebrae; Vincristine; Young Adult | 2011 |
Clinical effect of temozolomide-based chemotherapy in poorly differentiated endocrine carcinoma after progression on first-line chemotherapy.
Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Biomarkers, Tumor; Capecitabine; Carcinoma, Neuroendocrine; Cisplatin; Dacarbazine; Deoxycytidine; Disease Progression; Disease-Free Survival; DNA Methylation; DNA Modification Methylases; DNA Repair; DNA Repair Enzymes; Drug Administration Schedule; Etoposide; Female; Fluorouracil; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Promoter Regions, Genetic; Retrospective Studies; Salvage Therapy; Temozolomide; Treatment Outcome; Tumor Suppressor Proteins | 2011 |
Chemosensitization of glioblastoma cells by the histone deacetylase inhibitor MS275.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Apoptosis; Benzamides; Blotting, Western; Cell Line, Tumor; Central Nervous System Neoplasms; Cisplatin; Dacarbazine; Doxorubicin; Drug Synergism; Etoposide; Glioblastoma; Histone Deacetylase Inhibitors; Histones; Humans; Microtubules; Pyridines; Temozolomide | 2011 |
Ifosfamide, carboplatin and etoposide in recurrent malignant glioma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Carboplatin; Dacarbazine; Drug Administration Schedule; Etoposide; Female; Glioma; Humans; Ifosfamide; Male; Middle Aged; Recurrence; Retrospective Studies; Temozolomide; Treatment Failure | 2011 |
Inhibition of coding region determinant binding protein sensitizes melanoma cells to chemotherapeutic agents.
Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Dacarbazine; Down-Regulation; Drug Resistance, Neoplasm; Etoposide; Gene Knockdown Techniques; Humans; Melanoma; Microphthalmia-Associated Transcription Factor; Neoplasm Proteins; RNA-Binding Proteins; RNA, Small Interfering; Temozolomide; Vinblastine | 2012 |
Avastin: more questions than answers. . .
Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Camptothecin; Chemoradiotherapy; Dacarbazine; Etoposide; Female; Glioblastoma; Glioma; Humans; Male; Neoplasm Recurrence, Local; Salvage Therapy; Supratentorial Neoplasms; Temozolomide | 2012 |
Metronomic chemotherapy with the COMBAT regimen in advanced pediatric malignancies: a multicenter experience.
Topics: Administration, Metronomic; Adolescent; Adult; Angiogenesis Inhibitors; Antineoplastic Combined Chemotherapy Protocols; Celecoxib; Child; Child, Preschool; Dacarbazine; Etoposide; Europe; Feasibility Studies; Female; Fenofibrate; Humans; Infant; Isotretinoin; Male; Neoplasms; Pyrazoles; Registries; Sulfonamides; Temozolomide; Vitamin D; Young Adult | 2012 |
Potentiation of etoposide and temozolomide cytotoxicity by curcumin and turmeric force™ in brain tumor cell lines.
Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cerebellar Neoplasms; Curcuma; Curcumin; Dacarbazine; Dose-Response Relationship, Drug; Drug Synergism; Etoposide; Glioblastoma; Humans; Inhibitory Concentration 50; Medulloblastoma; Phytotherapy; Plant Extracts; Plants, Medicinal; Rhizome; Temozolomide | 2012 |
5-day/5-drug myeloablative outpatient regimen for resistant neuroblastoma.
Topics: 3-Iodobenzylguanidine; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carboplatin; Child; Child, Preschool; Combined Modality Therapy; Cyclophosphamide; Dacarbazine; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Humans; Irinotecan; Male; Neuroblastoma; Outpatients; Radionuclide Imaging; Radiopharmaceuticals; Retrospective Studies; Salvage Therapy; Temozolomide | 2013 |
Equinatoxin II potentiates temozolomide- and etoposide-induced glioblastoma cell death.
Topics: Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Brain Neoplasms; Cell Line, Tumor; Cnidarian Venoms; Dacarbazine; Drug Synergism; Etoposide; Glioblastoma; Humans; Immunohistochemistry; Magnetic Resonance Imaging; Male; Mice; Mice, Inbred C57BL; Temozolomide | 2012 |
Relapse in medulloblastoma: what can be done after abandoning high-dose chemotherapy? A mono-institutional experience.
Topics: Administration, Intravenous; Administration, Oral; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Camptothecin; Cerebellar Neoplasms; Child; Child, Preschool; Cisplatin; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Cranial Irradiation; Dacarbazine; Deoxycytidine; Disease Progression; Disease-Free Survival; Etoposide; Female; Gemcitabine; Humans; Irinotecan; Male; Medulloblastoma; Melphalan; Neoplasm Recurrence, Local; Organoplatinum Compounds; Oxaliplatin; Patient Selection; Quality of Life; Radiotherapy; Retrospective Studies; Salvage Therapy; Temozolomide; Young Adult | 2013 |
Retrospective analysis of bevacizumab in combination with ifosfamide, carboplatin, and etoposide in patients with second recurrence of glioblastoma.
Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Carboplatin; Combined Modality Therapy; Dacarbazine; Disease-Free Survival; Drug Administration Schedule; Etoposide; Female; Glioblastoma; Hematologic Diseases; Humans; Ifosfamide; Interferons; Kaplan-Meier Estimate; Male; Middle Aged; Neoplasm Recurrence, Local; Retrospective Studies; Salvage Therapy; Temozolomide; Treatment Outcome | 2013 |
Quantitative measurement of alterations in DNA damage repair (DDR) pathways using single cell network profiling (SCNP).
Topics: Adult; Ataxia Telangiectasia Mutated Proteins; BRCA1 Protein; BRCA2 Protein; Cell Cycle; Cell Line, Tumor; Child; Cyclin A2; Dacarbazine; DNA Breaks, Double-Stranded; DNA Damage; DNA Repair; Enzyme Inhibitors; Etoposide; Haploinsufficiency; Histones; Homologous Recombination; Humans; Mutagens; Phosphorylation; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Reproducibility of Results; Single-Cell Analysis; Temozolomide | 2014 |
Anticancer potential and mechanism of action of mango ginger (Curcuma amada Roxb.) supercritical CO₂ extract in human glioblastoma cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Carbon Dioxide; Cell Line, Tumor; Cell Survival; Curcuma; Dacarbazine; Etoposide; Glioblastoma; Humans; Mice; Plant Extracts; Reverse Transcriptase Polymerase Chain Reaction; Temozolomide | 2015 |
Treatment results and prognostic factors for intracranial nongerminomatous germ cell tumors: single institute experience.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Brain Neoplasms; Chemotherapy, Adjuvant; Child; Child, Preschool; Cisplatin; Combined Modality Therapy; Craniospinal Irradiation; Dacarbazine; Disease-Free Survival; Etoposide; Female; Humans; Magnetic Resonance Imaging; Male; Neoplasms, Germ Cell and Embryonal; Neurosurgical Procedures; Prognosis; Retrospective Studies; Survival Rate; Temozolomide; Treatment Outcome; Vinblastine; Young Adult | 2015 |
The effect of silibinin in enhancing toxicity of temozolomide and etoposide in p53 and PTEN-mutated resistant glioma cell lines.
Topics: Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; Drug Resistance, Neoplasm; Drug Synergism; Etoposide; Genes, p53; Glioma; Humans; Inhibitor of Apoptosis Proteins; Mutation; PTEN Phosphohydrolase; Silybin; Silymarin; Survivin; Temozolomide | 2015 |
PARP Inhibitors Sensitize Ewing Sarcoma Cells to Temozolomide-Induced Apoptosis via the Mitochondrial Pathway.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Dacarbazine; Dactinomycin; Doxorubicin; Drug Synergism; Etoposide; G2 Phase Cell Cycle Checkpoints; Humans; Ifosfamide; Metabolic Networks and Pathways; Mitochondria; Phthalazines; Piperazines; Poly(ADP-ribose) Polymerase Inhibitors; Sarcoma, Ewing; Temozolomide; Vincristine | 2015 |
Synovial sarcoma cell lines showed reduced DNA repair activity and sensitivity to a PARP inhibitor.
Topics: Cell Line, Tumor; Cell Proliferation; Dacarbazine; DNA Damage; DNA Repair; Etoposide; Humans; Phthalazines; Piperazines; Poly(ADP-ribose) Polymerase Inhibitors; Radiation, Ionizing; Recombinational DNA Repair; Sarcoma, Synovial; Temozolomide; Topoisomerase II Inhibitors | 2016 |
PARP Inhibitor Activity Correlates with SLFN11 Expression and Demonstrates Synergy with Temozolomide in Small Cell Lung Cancer.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Cell Line, Tumor; Cisplatin; Dacarbazine; Drug Synergism; Etoposide; Gene Expression Regulation, Neoplastic; Genomics; Humans; Indoles; Mice; Nuclear Proteins; Phthalazines; Piperazines; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Small Cell Lung Carcinoma; Temozolomide; Xenograft Model Antitumor Assays | 2017 |
Acute myeloid leukemia therapy elicits durable complete response in chemoradio-resistant metastatic paraganglioma.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Cytarabine; Dacarbazine; Daunorubicin; Drug Resistance, Neoplasm; Etoposide; Humans; Iodobenzenes; Leukemia, Myeloid, Acute; Male; Paraganglioma; Radiation Tolerance; Temozolomide | 2017 |
The Effect of Ascorbic Acid over the Etoposide- and Temozolomide-Mediated Cytotoxicity in Glioblastoma Cell Culture: A Molecular Study.
Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Ascorbic Acid; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Central Nervous System Neoplasms; Dacarbazine; DNA Damage; Drug Synergism; Etoposide; Glioblastoma; Humans; Temozolomide | 2018 |
Concurrent radiotherapy with temozolomide vs. concurrent radiotherapy with a cisplatinum-based polychemotherapy regimen : Acute toxicity in pediatric high-grade glioma patients.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemoradiotherapy; Child; Child, Preschool; Cisplatin; Cohort Studies; Dacarbazine; Etoposide; Female; Glioma; Humans; Ifosfamide; Leukopenia; Male; Neoplasm Grading; Prospective Studies; Temozolomide; Treatment Outcome; Vincristine | 2018 |
A HIF-independent, CD133-mediated mechanism of cisplatin resistance in glioblastoma cells.
Topics: AC133 Antigen; Basic Helix-Loop-Helix Transcription Factors; Brain Neoplasms; Cell Line, Tumor; Cisplatin; Dacarbazine; Drug Resistance, Neoplasm; Etoposide; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; RNA, Messenger; Temozolomide; Tumor Hypoxia; Vascular Endothelial Growth Factors | 2018 |
The clinical conundrum of managing relapsed small cell lung cancer.
Topics: Anthracyclines; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Immunological; Antineoplastic Combined Chemotherapy Protocols; Benzodiazepinones; Carboplatin; Clinical Decision-Making; Disease Progression; Etoposide; Humans; Immunoconjugates; Irinotecan; Liver Neoplasms; Lung Neoplasms; Molecular Targeted Therapy; Neoplasm Recurrence, Local; Nivolumab; Paclitaxel; Piperazines; Pyrimidines; Salvage Therapy; Small Cell Lung Carcinoma; Temozolomide; Thiourea; Topotecan | 2019 |
Temozolomide and etoposide combination for the treatment of relapsed osteosarcoma.
Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Etoposide; Female; Humans; Male; Neoplasm Recurrence, Local; Osteosarcoma; Prognosis; Retrospective Studies; Temozolomide; Young Adult | 2020 |
Case Report: Exceptional Response to Second Line Temozolomide Therapy in a Patient With Metastatic Adrenocortical Carcinoma.
Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Doxorubicin; Etoposide; Female; Humans; Mitotane; Prognosis; Remission Induction; Temozolomide; Young Adult | 2021 |
Intensive Multimodal Therapy Combined With Long-term Temozolomide and Etoposide Treatment for Recurrent Osteosarcoma to the Liver and Stomach.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Combined Modality Therapy; Etoposide; Humans; Liver; Neoplasm Recurrence, Local; Osteosarcoma; Stomach; Temozolomide | 2022 |