etoposide has been researched along with sphingosine in 23 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (21.74) | 18.2507 |
| 2000's | 13 (56.52) | 29.6817 |
| 2010's | 5 (21.74) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Don, AS; Martinez-Lamenca, C; Proia, RL; Roberts, E; Rosen, H; Webb, WR | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Yung, BY | 1 |
| Brossmer, R; Geilen, CC; Hannun, YA; Ihrig, P; Kolter, T; Orfanos, CE; Perry, D; Sadeghlar, F; Sandhoff, K; Wieder, T | 1 |
| Driscoll, TA; Hannun, YA; Obeid, LM; Zhang, J | 1 |
| Carabillò, M; Emanuele, S; Giuliano, M; Lauricella, M; Tesoriere, G; Vento, R | 1 |
| Boustany, RM; Guo, WX; Nikbakht, K; Puranam, KL; Qian, WH | 1 |
| Carton, J; Hannun, YA; Meredith, F; Perry, DK; Shah, AK; Uhlinger, DJ | 1 |
| Aizu-Yokota, E; Hasegawa, M; Kasahara, T; Momoi, T; Sakurai, S; Sonoda, Y; Yamamoto, D | 1 |
| Cho, S; Dawson, G; Dawson, PE | 1 |
| Amano, T; Fujino, M; Funeshima, N; Guo, L; Kawasaki, M; Kitazawa, Y; Li, XK; Suzuki, S | 1 |
| Faden, AI; Milstien, S; Movsesyan, V; Murthy, SK; Spiegel, S; Toman, RE | 1 |
| Dawson, G; Dawson, SA; Moskal, JR | 1 |
| Eguchi, K; Hida, A; Huang, M; Ida, H; Izumi, Y; Kawakami, A; Miyashita, T; Nakamura, H; Nakashima, K; Origuchi, T; Tamai, M; Tanaka, F; Ueki, Y; Yamasaki, S | 1 |
| Dong, ZR; Hao, HL; Jiang, LL; Li, XL; Liu, ZL; Luo, JM; Pan, L; Wang, FX; Yang, JC; Zhang, XJ | 1 |
| Alexander, H; Alexander, S; Hanigan, MH; Min, J; Stegner, AL; Traynor, D; Zhang, L | 1 |
| Brüne, B; Schnitzer, SE; Weigert, A; Zhou, J | 1 |
| Kepp, O; Kroemer, G; Martins, I; Métivier, D; Michaud, M; Perfettini, JL; Schlemmer, F; Senovilla, L; Séror, C; Tesniere, A; Zitvogel, L | 1 |
| Antoon, JW; Beckman, BS | 1 |
| Faden, AI; Hanscom, M; Piao, CS; Sabirzhanov, B; Stoica, BA | 1 |
| Han, Y; Ma, DH; Wang, ZH; Xing, Y | 1 |
| Becker, S; Brodde, M; Burkhardt, R; Ceglarek, U; Christoffersen, C; Feuerborn, R; Nagel, P; Nofer, JR; Potì, F; Schmidt, H | 1 |
| Faissner, A; Joachim, SC; Kakkassery, V; Kleuser, B; Kociok, N; Lüth, A; Reinhard, J; Skosyrski, S; Tate, R; van der Giet, M | 1 |
23 other study(ies) available for etoposide and sphingosine
| Article | Year |
|---|---|
Essential requirement for sphingosine kinase 2 in a sphingolipid apoptosis pathway activated by FTY720 analogues.
Topics: Animals; Apoptosis; Autoimmune Diseases; bcl-2-Associated X Protein; Calcium Signaling; Caspases; Cell Membrane Permeability; Drug Resistance, Neoplasm; Endoplasmic Reticulum; Fingolimod Hydrochloride; HeLa Cells; Humans; Immunosuppressive Agents; Jurkat Cells; Lymphoproliferative Disorders; Mice; Mice, Knockout; Mitochondria; Mutagenesis; Organ Specificity; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Propylene Glycols; Protein Transport; Receptors, Lysosphingolipid; Sphingolipids; Sphingosine; Spleen; Thymus Gland | 2007 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Sphinganine potentiation of cellular differentiation induced by various anti-leukemia drugs in human leukemia cell line HL-60.
Topics: Antineoplastic Agents; Calcium; Cell Differentiation; Cell Line; Egtazic Acid; Etoposide; Humans; Leukemia, Myeloid; Protein Kinase C; Sphingosine; Verapamil | 1994 |
Bcl-2 antagonizes apoptotic cell death induced by two new ceramide analogues.
Topics: Amides; Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Cell Survival; Ceramides; Etoposide; Genes, bcl-2; Humans; Molecular Structure; Poly(ADP-ribose) Polymerases; Sphingosine; Transfection; Trypan Blue; Tumor Cells, Cultured | 1997 |
Regulation of membrane release in apoptosis.
Topics: Apoptosis; Arachidonic Acid; Cell Membrane; Cysteine Proteinase Inhibitors; Etoposide; HL-60 Cells; Humans; Kinetics; Leukemia, B-Cell; Membrane Lipids; Palmitic Acid; Phospholipases A; Phospholipases A2; Preleukemia; Proto-Oncogene Proteins c-bcl-2; Recombinant Proteins; Sphingosine; Transfection; Tumor Cells, Cultured; Vincristine | 1998 |
Increased cyclin E level in retinoblastoma cells during programmed cell death.
Topics: Amsacrine; Apoptosis; Camptothecin; Cyclin A; Cyclin E; Enzyme Inhibitors; Etoposide; Humans; Interleukin-1; Retinoblastoma; Sphingosine; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1998 |
CLN3 defines a novel antiapoptotic pathway operative in neurodegeneration and mediated by ceramide.
Topics: Apoptosis; Blotting, Western; Cell Division; Cell Line; Cell Survival; Cells, Cultured; Ceramides; Cyclins; Dose-Response Relationship, Drug; Etoposide; Humans; Membrane Glycoproteins; Models, Biological; Molecular Chaperones; Neurodegenerative Diseases; Poly(ADP-ribose) Polymerases; Reverse Transcriptase Polymerase Chain Reaction; Saccharomyces cerevisiae Proteins; Sphingosine; Staurosporine; Time Factors; Transfection; Vincristine | 1999 |
Serine palmitoyltransferase regulates de novo ceramide generation during etoposide-induced apoptosis.
Topics: Acyltransferases; Antineoplastic Agents, Phytogenic; Apoptosis; Biological Transport; Caspases; Ceramides; Enzyme Activation; Etoposide; Humans; Leukemia; Microsomes; Models, Biological; Mycotoxins; Oxidoreductases; Palmitates; Poly(ADP-ribose) Polymerases; Protease Inhibitors; Serine C-Palmitoyltransferase; Sphingosine; Trypan Blue; Tumor Cells, Cultured | 2000 |
FTY720, a novel immunosuppressive agent, induces apoptosis in human glioma cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Caspase 3; Caspase 6; Caspases; Cell Death; Cell Survival; Cysteine Proteinase Inhibitors; DNA Fragmentation; Dose-Response Relationship, Drug; Enzyme Activation; Etoposide; Fingolimod Hydrochloride; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Glioma; Humans; Immunosuppressive Agents; Oligopeptides; Phosphatidylinositol 3-Kinases; Phosphorylation; Propylene Glycols; Protein Serine-Threonine Kinases; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Sphingosine; Time Factors; Tumor Cells, Cultured; Tyrosine; Vanadates | 2001 |
Role of palmitoyl-protein thioesterase in cell death: implications for infantile neuronal ceroid lipofuscinosis.
Topics: Antibiotics, Antineoplastic; Apoptosis; Chromones; Daunorubicin; Enzyme Inhibitors; Etoposide; Humans; Infant; Morpholines; Nerve Degeneration; Neuroblastoma; Neuronal Ceroid-Lipofuscinoses; Neurons; Nucleic Acid Synthesis Inhibitors; Sphingosine; Staurosporine; Thiolester Hydrolases; Transfection; Tumor Cells, Cultured | 2001 |
Distinct pathways of apoptosis triggered by FTY720, etoposide, and anti-Fas antibody in human T-lymphoma cell line (Jurkat cells).
Topics: Antibodies; Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Caspases; DNA Fragmentation; Enzyme Activation; Enzyme Activators; Etoposide; fas Receptor; Fingolimod Hydrochloride; Gene Expression Regulation, Neoplastic; Genes, bcl-2; Humans; Immunosuppressive Agents; Indicators and Reagents; Jurkat Cells; Propylene Glycols; Sphingosine | 2002 |
Ceramide-induced cell death in primary neuronal cultures: upregulation of ceramide levels during neuronal apoptosis.
Topics: Animals; Animals, Newborn; Apoptosis; Brain; Cell Differentiation; Cell Membrane; Cell Survival; Cells, Cultured; Ceramides; Cerebellar Cortex; Cerebral Cortex; Dose-Response Relationship, Drug; Etoposide; Nerve Growth Factors; Neurons; Nucleic Acid Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Sphingomyelin Phosphodiesterase; Sphingomyelins; Sphingosine; Stress, Physiological; Up-Regulation | 2002 |
Transfection of 2,6 and 2,3-sialyltransferase genes and GlcNAc-transferase genes into human glioma cell line U-373 MG affects glycoconjugate expression and enhances cell death.
Topics: Antineoplastic Agents; beta-D-Galactoside alpha 2-6-Sialyltransferase; Caspase 3; Caspases; Cell Death; Cell Line, Tumor; Cell Membrane; Cell Survival; Chromones; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Enzyme Inhibitors; Etoposide; Glioma; Glycoconjugates; Glycosylation; Humans; Morpholines; N-Acetylglucosaminyltransferases; Oligosaccharides; Sialyltransferases; Sphingosine; Staurosporine; Transfection | 2004 |
Nitric oxide acts on the mitochondria and protects human endothelial cells from apoptosis.
Topics: Apoptosis; Arthritis, Rheumatoid; Caspases; Cell Division; Cells, Cultured; Endothelium, Vascular; Enzyme Activation; Etoposide; Humans; Leupeptins; Mitochondria; Nitric Oxide; Nitric Oxide Donors; S-Nitroso-N-Acetylpenicillamine; Sphingosine | 2004 |
mitochondrial ceramidase overexpression up-regulates Bcl-2 protein level in K562 cells, probably through its metabolite sphingosine-1-phosphate.
Topics: Amidohydrolases; Apoptosis; Arsenites; Ceramidases; Doxorubicin; Etoposide; Humans; K562 Cells; Lysophospholipids; Mitochondria; Oligonucleotides, Antisense; Proto-Oncogene Proteins c-bcl-2; Sphingosine; Up-Regulation | 2004 |
Sphingosine kinase regulates the sensitivity of Dictyostelium discoideum cells to the anticancer drug cisplatin.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Animals; Antineoplastic Agents; Blotting, Western; Cisplatin; Dictyostelium; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance; Etoposide; Fluorouracil; Microscopy, Fluorescence; Models, Genetic; Molecular Sequence Data; Mutation; Phosphotransferases (Alcohol Group Acceptor); Recombination, Genetic; Sensitivity and Specificity; Sequence Homology, Amino Acid; Sphingosine; Time Factors | 2005 |
Hypoxia enhances sphingosine kinase 2 activity and provokes sphingosine-1-phosphate-mediated chemoresistance in A549 lung cancer cells.
Topics: Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Death; Cell Hypoxia; Cell Line, Tumor; Culture Media; Drug Resistance, Neoplasm; Etoposide; Humans; Lung Neoplasms; Lysophospholipids; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphotransferases (Alcohol Group Acceptor); Receptors, Lysosphingolipid; RNA, Small Interfering; Sphingosine; Transfection | 2009 |
Chemotherapy induces ATP release from tumor cells.
Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; Apoptosis; Cadmium; Cell Line, Tumor; Cisplatin; Etoposide; Flow Cytometry; Fluorescent Antibody Technique; Mice; Mitomycin; Mitoxantrone; Neoplasms; Organoplatinum Compounds; Oxaliplatin; Sphingosine; Thapsigargin | 2009 |
Anti-proliferative effects of the novel ceramide analog (S)-2-(benzylideneamino)-3-hydroxy-N-tetrade-cylpropanamide in chemoresistant cancer.
Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Ceramides; Doxorubicin; Drug Resistance, Neoplasm; Drug Synergism; Etoposide; Female; Humans; Ki-67 Antigen; Lysophospholipids; Sphingosine; Stereoisomerism; Structure-Activity Relationship | 2012 |
Over-expression of HSP70 attenuates caspase-dependent and caspase-independent pathways and inhibits neuronal apoptosis.
Topics: Amyloid beta-Peptides; Animals; Apoptosis; Apoptosis Regulatory Proteins; Caspases; Cells, Cultured; Cerebral Cortex; Embryo, Mammalian; Etoposide; Gene Expression Regulation; Green Fluorescent Proteins; HSP70 Heat-Shock Proteins; Humans; Immunoprecipitation; Neural Inhibition; Neuroblastoma; Neurons; Peptide Fragments; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Protein Binding; Rats; Signal Transduction; Sphingosine; Staurosporine; Transfection | 2012 |
FTY720 enhances chemosensitivity of colon cancer cells to doxorubicin and etoposide via the modulation of P-glycoprotein and multidrug resistance protein 1.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Apoptosis; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Cell Survival; Chemotherapy, Adjuvant; Colonic Neoplasms; Doxorubicin; Drug Resistance, Neoplasm; Etoposide; Fingolimod Hydrochloride; Gene Expression; Humans; Immunosuppressive Agents; Propylene Glycols; Sphingosine | 2014 |
High density lipoprotein (HDL)-associated sphingosine 1-phosphate (S1P) inhibits macrophage apoptosis by stimulating STAT3 activity and survivin expression.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Cytoprotection; Dose-Response Relationship, Drug; Endoplasmic Reticulum Stress; Etoposide; Inhibitor of Apoptosis Proteins; Janus Kinase 2; Lipoproteins, HDL; Lysophospholipids; Macrophages; Mice; Mitochondria; RAW 264.7 Cells; Repressor Proteins; Signal Transduction; Sphingosine; STAT3 Transcription Factor; Survivin; Thapsigargin; Time Factors | 2017 |
Etoposide Upregulates Survival Favoring Sphingosine-1-Phosphate in Etoposide-Resistant Retinoblastoma Cells.
Topics: Antineoplastic Agents, Phytogenic; Cell Proliferation; Cell Survival; Drug Resistance, Neoplasm; Etoposide; Humans; Lysophospholipids; Retinoblastoma; Sphingosine; Tumor Cells, Cultured | 2019 |