Page last updated: 2024-08-23

etoposide and quercetin

etoposide has been researched along with quercetin in 36 studies

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (5.56)18.2507
2000's15 (41.67)29.6817
2010's17 (47.22)24.3611
2020's2 (5.56)2.80

Authors

AuthorsStudies
Bacsó, Z; Cianfriglia, M; Fenyvesi, F; Goda, K; Kappelmayer, J; Lustyik, G; Nagy, H; Szabó, G; Szilasi, M1
Lombardo, F; Obach, RS; Waters, NJ1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Ghosh, I; Manoharlal, R; Prakash, O; Prasad, R; Puri, N; Sharma, M1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Brouard, I; Burmistrova, O; Estévez, F; Estévez, S; Marrero, MT; Quintana, J; Welsch, I1
Bae, M; Choi, SU; Choi, SZ; Kim, CS; Kim, SY; Lee, KR; Oh, DC; Oh, J; Son, MW; Subedi, L; Suh, WS1
Corbett, AH; Osheroff, N; Robinson, MJ1
Ling, V; Shapiro, AB1
Gawron, A; Jakubowicz-Gil, J; Kandefer-Szerszeń, M; Paduch, R2
Chowdhury, AR; Goswami, A; Majumder, HK; Mandal, S; Mukhopadhyay, S; Sharma, S1
Cierniak, A; Kapiszewska, M; Papiez, M1
Dechsupa, S; Kothan, S; Leger, G; Mankhetkorn, S; Moretti, JL; Vergote, J1
Mikhailenko, VM; Philchenkov, AA; Zavelevich, MP1
Cierniak, A; Kapiszewska, M; Lomnicki, A; Papiez, MA; Pietrzycka, A; Stepniewski, M1
Cierniak, A; Elas, M; Kapiszewska, M; Lankoff, A1
Barjesteh van Waalwijk van Doorn-Khosrovani, S; Godschalk, RW; Janssen, J; Maas, LM; Nijhuis, JG; van Schooten, FJ1
Choi, JS; Li, X1
Green, KK; Keen, CL; Kwik-Uribe, C; Lanoue, L1
Blokhin, D; Philchenkov, A; Savinska, L; Zavelevich, M1
Fadlalla, K; Katkoori, V; Manne, U; Mosley, L; Samuel, T; Turner, T1
Choe, W; Chung, SH; Ha, J; Kang, I; Kim, HS; Kim, SS; Lee, S; Lim, JS; Wannatung, T; Yang, WK1
Papież, MA1
Fatma, S; Goswami, DG; Iqbal, Z; Negi, LM; Panda, AK; Talegaonkar, S; Tariq, M1
Krzyściak, W; Papież, MA1
Cao, Y; Feng, F; Hou, MX; Jia, H; Jiang, QY; Ma, HD; Sun, HW; Wang, T; Yang, Q; Yang, YP1
Aqaqe, N; Biechonski, S; Elad, D; Gourevich, D; Grisaru, D; Jaffa, AJ; Milyavsky, M; Olender, L; Rall, M; Raz, Y; Trakhtenbrot, L; Wiesmuller, L; Yassin, M; Zipin-Roitman, A1
Britt, RD; Kirkland, JL; LeBrasseur, N; Manlove, LJ; Pabelick, CM; Parikh, P; Prakash, YS; Ravix, J; Roesler, A; Sieck, GC; Teske, J; Thompson, MA; Tschumperlin, DJ; Wicher, SA1
Berman, C; Emmanuel, F; Goodenow, D; Richardson, C; Sahyouni, M1
Florian-Rodriguez, ME; Gaddam, NG; Hare, AM; Keller, P; Shi, H; Word, RA1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J1

Other Studies

36 other study(ies) available for etoposide and quercetin

ArticleYear
Distinct groups of multidrug resistance modulating agents are distinguished by competition of P-glycoprotein-specific antibodies.
    Biochemical and biophysical research communications, 2004, Mar-19, Volume: 315, Issue:4

    Topics: Adenosine Triphosphatases; Animals; Anti-Bacterial Agents; Antibodies, Monoclonal; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding, Competitive; Calcium Channel Blockers; Cyclosporine; Detergents; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flow Cytometry; Fluoresceins; Humans; Ivermectin; Mice; NIH 3T3 Cells; Substrate Specificity

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Analysis of physico-chemical properties of substrates of ABC and MFS multidrug transporters of pathogenic Candida albicans.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:11

    Topics: Candida albicans; Membrane Transport Proteins; Saccharomyces cerevisiae; Structure-Activity Relationship; Substrate Specificity

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
    Bioorganic & medicinal chemistry, 2012, Nov-15, Volume: 20, Issue:22

    Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Synthesis and effects on cell viability of flavonols and 3-methyl ether derivatives on human leukemia cells.
    European journal of medicinal chemistry, 2014, Sep-12, Volume: 84

    Topics: Antineoplastic Agents; Cell Death; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Flavonols; HL-60 Cells; Humans; Methyl Ethers; Molecular Structure; Structure-Activity Relationship; U937 Cells

2014
Anti-Neurodegenerative Biflavonoid Glycosides from Impatiens balsamina.
    Journal of natural products, 2017, 02-24, Volume: 80, Issue:2

    Topics: Algorithms; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biflavonoids; Glycosides; Humans; Impatiens; Lipopolysaccharides; Macrophages; Mice; Molecular Structure; Neuroprotective Agents; Nitric Oxide; Nuclear Magnetic Resonance, Biomolecular; Republic of Korea

2017
Effects of topoisomerase II-targeted drugs on enzyme-mediated DNA cleavage and ATP hydrolysis: evidence for distinct drug interaction domains on topoisomerase II.
    Biochemistry, 1993, Apr-13, Volume: 32, Issue:14

    Topics: Adenosine Triphosphate; Amsacrine; Animals; Anti-Infective Agents; Antineoplastic Agents; Binding Sites; Cell Nucleus; DNA Topoisomerases, Type II; DNA, Bacterial; Drosophila melanogaster; Escherichia coli; Etoposide; Fluoroquinolones; Genistein; Hydrolysis; Isoflavones; Novobiocin; Plasmids; Quercetin; Quinolones; Topoisomerase II Inhibitors

1993
Positively cooperative sites for drug transport by P-glycoprotein with distinct drug specificities.
    European journal of biochemistry, 1997, Nov-15, Volume: 250, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzimidazoles; Binding Sites; Biological Transport; Cell Line; Cell Membrane; Colchicine; Cricetinae; Cricetulus; Dactinomycin; Daunorubicin; Doxorubicin; Etoposide; Fluorescence; Fluorescent Dyes; Kinetics; Liposomes; Protein Binding; Quercetin; Rhodamine 123; Rhodamines; Vinblastine

1997
The effect of heat shock, cisplatin, etoposide and quercetin on Hsp27 expression in human normal and tumour cells.
    Folia histochemica et cytobiologica, 2002, Volume: 40, Issue:1

    Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Cell Culture Techniques; Cell Transformation, Neoplastic; Cisplatin; Drug Resistance, Neoplasm; Etoposide; Eukaryotic Cells; Fibroblasts; Heat-Shock Proteins; HeLa Cells; Hot Temperature; HSP27 Heat-Shock Proteins; Humans; Models, Biological; Molecular Chaperones; Neoplasm Proteins; Neoplasms; Quercetin; Stress, Physiological

2002
Luteolin, an emerging anti-cancer flavonoid, poisons eukaryotic DNA topoisomerase I.
    The Biochemical journal, 2002, Sep-01, Volume: 366, Issue:Pt 2

    Topics: Amsacrine; Animals; Antineoplastic Agents; Base Sequence; Betulinic Acid; Catalysis; Cell Nucleus; DNA, Superhelical; Enzyme Inhibitors; Etoposide; Flavonoids; Kinetics; Liver; Luteolin; Nucleic Acid Denaturation; Oligodeoxyribonucleotides; Pentacyclic Triterpenes; Plant Leaves; Quercetin; Rats; Spectrometry, Fluorescence; Topoisomerase I Inhibitors; Triterpenes

2002
The effect of cisplatin, etoposide and quercetin on Hsp72 expression.
    Polish journal of pathology : official journal of the Polish Society of Pathologists, 2002, Volume: 53, Issue:3

    Topics: Antineoplastic Agents; Blotting, Western; Cisplatin; Etoposide; Fibroblasts; Heat-Shock Proteins; HeLa Cells; Hot Temperature; HSP72 Heat-Shock Proteins; Humans; Laryngeal Neoplasms; Lung Neoplasms; Quercetin; Skin; Tumor Cells, Cultured

2002
Modulatory effect of quercetin on DNA damage, induced by etoposide in bone marrow cells and on changes in the activity of antioxidant enzymes in rats.
    Roczniki Akademii Medycznej w Bialymstoku (1995), 2004, Volume: 49 Suppl 1

    Topics: Animals; Bone Marrow Cells; Catalase; DNA Damage; Etoposide; Male; Quercetin; Rats; Rats, Wistar; Superoxide Dismutase

2004
Spontaneous mitochondrial membrane potential change during apoptotic induction by quercetin in K562 and K562/adr cells.
    Canadian journal of physiology and pharmacology, 2004, Volume: 82, Issue:12

    Topics: Annexins; Apoptosis; Cell Survival; Dose-Response Relationship, Drug; Etoposide; Flow Cytometry; Humans; K562 Cells; Membrane Potentials; Mitochondria; Quercetin; Radiopharmaceuticals; Technetium Tc 99m Sestamibi

2004
Analysis of 1H NMR-detectable mobile lipid domains for assessment of apoptosis induced by inhibitors of DNA synthesis and replication.
    Cell biology international, 2005, Volume: 29, Issue:1

    Topics: Apoptosis; Cell Line, Tumor; Cell Membrane; DNA Replication; Etoposide; Humans; Hydrogen; Magnetic Resonance Spectroscopy; Membrane Lipids; Quercetin; Vidarabine

2005
Prolonged quercetin administration diminishes the etoposide-induced DNA damage in bone marrow cells of rats.
    Drug and chemical toxicology, 2007, Volume: 30, Issue:1

    Topics: Animals; Bone Marrow Cells; Catalase; Comet Assay; DNA Damage; Etoposide; Female; Fluorescence Recovery After Photobleaching; Injections, Subcutaneous; Linear Models; Lung; Quercetin; Rats; Rats, Wistar; Superoxide Dismutase

2007
Lifespan of etoposide-treated human neutrophils is affected by antioxidant ability of quercetin.
    Toxicology in vitro : an international journal published in association with BIBRA, 2007, Volume: 21, Issue:6

    Topics: Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; Cell Survival; Cells, Cultured; DNA Damage; Etoposide; Humans; Hydrogen Peroxide; Neutrophils; Peroxidase; Phenols; Quercetin; Reactive Oxygen Species

2007
Dietary flavonoids induce MLL translocations in primary human CD34+ cells.
    Carcinogenesis, 2007, Volume: 28, Issue:8

    Topics: Antigens, CD34; Cells, Cultured; Dietary Supplements; DNA Breaks, Double-Stranded; Etoposide; Flavonoids; Genistein; Histone-Lysine N-Methyltransferase; Humans; Kaempferols; Leukemia; Leukocytes, Mononuclear; Myeloid-Lymphoid Leukemia Protein; Quercetin; Translocation, Genetic

2007
Effects of quercetin on the pharmacokinetics of Etoposide after oral or intravenous administration of etoposide in rats.
    Anticancer research, 2009, Volume: 29, Issue:4

    Topics: Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; Antioxidants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Availability; Chromatography, High Pressure Liquid; Drug Combinations; Drug Interactions; Etoposide; Infusions, Intravenous; Male; Metabolic Clearance Rate; Quercetin; Rats; Rats, Sprague-Dawley

2009
Dietary factors and the risk for acute infant leukemia: evaluating the effects of cocoa-derived flavanols on DNA topoisomerase activity.
    Experimental biology and medicine (Maywood, N.J.), 2010, Volume: 235, Issue:1

    Topics: Cacao; Cell Line; Diet; Dimerization; Etoposide; Female; Flavonoids; HL-60 Cells; Humans; Infant; Leukemia, Myeloid, Acute; Pregnancy; Prenatal Exposure Delayed Effects; Quercetin; Risk Factors; Topoisomerase II Inhibitors

2010
Jurkat/A4 cells with multidrug resistance exhibit reduced sensitivity to quercetin.
    Experimental oncology, 2010, Volume: 32, Issue:2

    Topics: Antineoplastic Agents; Antioxidants; Apoptosis; Blotting, Western; Cell Cycle; Cell Proliferation; Cell Separation; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Etoposide; Flow Cytometry; Gene Expression; Gene Expression Profiling; Humans; Jurkat Cells; Quercetin

2010
Dual-mode interaction between quercetin and DNA-damaging drugs in cancer cells.
    Anticancer research, 2012, Volume: 32, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Camptothecin; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Cyclin B1; Cyclin-Dependent Kinase Inhibitor p21; DNA Damage; Drug Synergism; Etoposide; Flow Cytometry; Fluorouracil; Humans; Inhibitor of Apoptosis Proteins; Male; Prostatic Neoplasms; Quercetin; Survivin; Tumor Stem Cell Assay; Tumor Suppressor Protein p53

2012
Quercetin enhances hypoxia-mediated apoptosis via direct inhibition of AMPK activity in HCT116 colon cancer.
    Apoptosis : an international journal on programmed cell death, 2012, Volume: 17, Issue:9

    Topics: AMP-Activated Protein Kinases; Animals; Antineoplastic Agents; Antioxidants; Apoptosis; Cell Hypoxia; Cell Line, Tumor; Cisplatin; Colonic Neoplasms; Etoposide; Genes, Reporter; Humans; Hypoxia-Inducible Factor 1; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Quercetin; Signal Transduction; Xenograft Model Antitumor Assays

2012
The effect of quercetin on oxidative DNA damage and myelosuppression induced by etoposide in bone marrow cells of rats.
    Acta biochimica Polonica, 2014, Volume: 61, Issue:1

    Topics: Animals; Antioxidants; Apoptosis; Bone Marrow Cells; DNA Damage; Etoposide; Humans; Leukemia, Myeloid, Acute; Oxidation-Reduction; Quercetin; Rats

2014
Novel flavonoid-based biodegradable nanoparticles for effective oral delivery of etoposide by P-glycoprotein modulation: an in vitro, ex vivo and in vivo investigations.
    Drug delivery, 2016, Volume: 23, Issue:2

    Topics: Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B; Biological Availability; Breast Neoplasms; Cell Separation; Cell Survival; Dose-Response Relationship, Drug; Drug Carriers; Drug Compounding; Etoposide; Female; Flow Cytometry; Fluorescent Dyes; Humans; Inhibitory Concentration 50; Intestinal Absorption; Lactic Acid; Male; MCF-7 Cells; Microscopy, Confocal; Nanoparticles; Nanotechnology; Permeability; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polyvinyl Alcohol; Quercetin; Rats, Wistar; Rhodamines; Solubility; Sonication; Technology, Pharmaceutical

2016
The antioxidant quercetin protects HL-60 cells with high myeloperoxidase activity against pro-oxidative and apoptotic effects of etoposide.
    Acta biochimica Polonica, 2014, Volume: 61, Issue:4

    Topics: Antioxidants; Apoptosis; Etoposide; HL-60 Cells; Humans; Oxidation-Reduction; Peroxidase; Quercetin; Reactive Oxygen Species

2014
Rhamnetin induces sensitization of hepatocellular carcinoma cells to a small molecular kinase inhibitor or chemotherapeutic agents.
    Biochimica et biophysica acta, 2016, Volume: 1860, Issue:7

    Topics: Animals; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Cell Survival; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Etoposide; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; Inhibitory Concentration 50; Liver Neoplasms; Male; Mice, SCID; MicroRNAs; Niacinamide; Paclitaxel; Phenylurea Compounds; Protein Kinase Inhibitors; Quercetin; Receptor, Notch1; Signal Transduction; Sorafenib; Transfection; Xenograft Model Antitumor Assays

2016
Quercetin alters the DNA damage response in human hematopoietic stem and progenitor cells via TopoII- and PI3K-dependent mechanisms synergizing in leukemogenic rearrangements.
    International journal of cancer, 2017, 02-15, Volume: 140, Issue:4

    Topics: Adult; Ascorbic Acid; Cell Culture Techniques; Cell Transformation, Neoplastic; Cells, Cultured; Colony-Forming Units Assay; DNA Damage; DNA Repair; DNA Topoisomerases, Type II; Dose-Response Relationship, Drug; Etoposide; Female; Genistein; Hematopoietic Stem Cells; Histone-Lysine N-Methyltransferase; Histones; Humans; Infant; Leukemia; Maternal-Fetal Exchange; Myeloid-Lymphoid Leukemia Protein; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Pregnancy; Quercetin; Signal Transduction; Topoisomerase II Inhibitors

2017
Hyperoxia-induced Cellular Senescence in Fetal Airway Smooth Muscle Cells.
    American journal of respiratory cell and molecular biology, 2019, Volume: 61, Issue:1

    Topics: Biomarkers; Cell Cycle; Cellular Senescence; Cytokines; Dasatinib; DNA Damage; Etoposide; Extracellular Matrix; Extracellular Matrix Proteins; Fetus; Humans; Hyperoxia; Inflammation Mediators; Lung; Models, Biological; Myocytes, Smooth Muscle; Phenotype; Quercetin

2019
Bioflavonoids cause DNA double-strand breaks and chromosomal translocations through topoisomerase II-dependent and -independent mechanisms.
    Mutation research. Genetic toxicology and environmental mutagenesis, 2020, Volume: 849

    Topics: Animals; Cell Line; Chromosome Breakpoints; Chromosomes, Mammalian; Dexrazoxane; DNA; DNA Breaks, Double-Stranded; DNA Repair; DNA Topoisomerases, Type II; Etoposide; Flavonoids; Genistein; Histones; Kaempferols; Luteolin; Mice; Mouse Embryonic Stem Cells; Quercetin; Topoisomerase II Inhibitors; Translocation, Genetic

2020
Induction of Cellular Senescence in Rat Vaginal Fibroblasts and Treatment With Senolytics: An in Vitro Model for the Study of Pelvic Organ Prolapse.
    Female pelvic medicine & reconstructive surgery, 2022, 05-01, Volume: 28, Issue:5

    Topics: Animals; Biomarkers; Cellular Senescence; Dasatinib; Etoposide; Female; Fibroblasts; Humans; Matrix Metalloproteinase 7; Matrix Metalloproteinase 9; Pelvic Organ Prolapse; Quercetin; Rats; Senotherapeutics

2022
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
    Nature chemical biology, 2009, Volume: 5, Issue:10

    Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection

2009