etoposide has been researched along with novobiocin in 51 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 10 (19.61) | 18.7374 |
1990's | 22 (43.14) | 18.2507 |
2000's | 7 (13.73) | 29.6817 |
2010's | 12 (23.53) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Hansch, C; Khwaja, TA; Selassie, CD | 1 |
Barrows, LR; Ireland, CM; Kokoshka, JM | 1 |
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL | 1 |
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
Benet, LZ; Brouwer, KL; Chu, X; Dahlin, A; Evers, R; Fischer, V; Giacomini, KM; Hillgren, KM; Hoffmaster, KA; Huang, SM; Ishikawa, T; Keppler, D; Kim, RB; Lee, CA; Niemi, M; Polli, JW; Sugiyama, Y; Swaan, PW; Tweedie, DJ; Ware, JA; Wright, SH; Yee, SW; Zamek-Gliszczynski, MJ; Zhang, L | 1 |
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
Ghosh, I; Manoharlal, R; Prakash, O; Prasad, R; Puri, N; Sharma, M | 1 |
Ekins, S; Williams, AJ; Xu, JJ | 1 |
Jun, KY; Jung, MJ; Kwon, Y; Lee, ES; Lee, EY; Lee, OH; Na, Y; Park Choo, HY | 1 |
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
Chang, IH; Jun, KY; Kwon, Y; Lee, E; Lee, ES; Na, Y; Park, SE | 1 |
Bist, G; Jun, KY; Kadayat, TM; Kwon, Y; Lee, ES; Park, S; Shrestha, A; Thapa Magar, TB | 1 |
Benedetto Tiz, D; Draskovits, G; Durante Cruz, C; Durcik, M; Ilaš, J; Kikelj, D; Lovison, D; Nyerges, Á; Pál, C; Peterlin Mašič, L; Skok, Ž; Tammela, P; Tomašič, T; Zidar, N | 1 |
Cruz, CD; Draskovits, G; Durcik, M; Ilaš, J; Kikelj, D; Mašič, LP; Nyerges, Á; Pál, C; Révész, T; Skok, Ž; Tammela, P; Tiz, DB; Tomašič, T; Zega, A; Zidar, N; Žigon, D | 1 |
Lorico, A; Rappa, G; Sartorelli, AC | 4 |
Constantinou, A; Grdina, D; Huberman, E; Kiguchi, K | 1 |
Aller, P; Bernabeu, C; Cabañas, C; Mata, F; Rius, C; Zorrilla, AR | 1 |
Elkind, MM; Shibuya, ML; Utsumi, H | 1 |
Andrews, PA; Howell, SB; Katz, EJ; Kling, KM; Vick, JS | 1 |
Bohr, V; Hanawalt, P; Mansbridge, J | 1 |
Kort, L; Rowley, R | 1 |
Denyer, SP; Dewick, PM; Figgitt, DP; Jackson, DE; Williams, P | 1 |
Forterre, P; Sioud, M | 1 |
Downes, CS; Johnson, RT; Mullinger, AM | 1 |
Duguet, M; Jaxel, C; Mirambeau, G; Panijel, J; Portemer, C; Taudou, G | 1 |
Beerman, TA; Sigmund, RD; Woynarowski, JM | 1 |
Baldacci, G; de Recondo, AM; Forterre, P; Sioud, M | 1 |
Liu, LF; Rowe, TC; Yang, L | 1 |
Lönn, S; Lönn, U | 1 |
Deisher, TA; Harlan, JM; Kaushansky, K | 1 |
Catapano, CV; Fernandes, DJ; Germino, JF; Lorico, A; Rappa, G; Sartorelli, AC; Srimatkandada, S | 1 |
Forsgren, A; Riesbeck, K | 1 |
Holden, SA; Northey, D; Robinson, MF; Rosowsky, A; Teicher, BA | 1 |
Filatov, MV; Varfolomeeva, EY | 1 |
Macfarlane, DE; O'Donnell, PS | 1 |
Corbett, AH; Osheroff, N; Robinson, MJ | 1 |
Corbett, AH; Hong, D; Osheroff, N | 1 |
McCabe, MJ; Orrenius, S | 1 |
Cattan, AR; Douglas, EA; Levett, D; Middleton, PG; Taylor, PR | 1 |
Falaschi, A; Ochem, A; Phan, TN; Tuteja, N; Tuteja, R | 1 |
Phan, TN; Tuteja, N | 1 |
Johnson, LM; Lorico, A; Murren, JR; Rappa, G; Sartorelli, AC | 1 |
Fodstad, O; Lorico, A; Rappa, G; Sartorelli, AC; Shyam, K | 1 |
Cavalcanti, DP; de Souza, W; Fragoso, SP; Goldenberg, S; Motta, MC | 1 |
Boudabous, A; Cekaite, L; Sioud, M | 1 |
Pham, XH; Tran, NQ; Tuteja, N; Tuteja, R | 1 |
1 review(s) available for etoposide and novobiocin
Article | Year |
---|---|
Membrane transporters in drug development.
Topics: Animals; Computer Simulation; Decision Trees; Drug Approval; Drug Discovery; Drug Evaluation, Preclinical; Drug Interactions; Humans; Membrane Transport Proteins; Mice; Mice, Knockout; Prescription Drugs | 2010 |
50 other study(ies) available for etoposide and novobiocin
Article | Year |
---|---|
Structure-activity relationships of antineoplastic agents in multidrug resistance.
Topics: Animals; Antineoplastic Agents; Cell Line; Cell Survival; Cricetinae; Dactinomycin; Drug Resistance; Leukemia L1210; Mice; Regression Analysis; Structure-Activity Relationship; Tumor Cells, Cultured | 1990 |
Cell-based screen for identification of inhibitors of tubulin polymerization.
Topics: Animals; Brain Neoplasms; Bucladesine; Cell Differentiation; Drug Screening Assays, Antitumor; Formazans; Glioma; Rats; Tubulin; Tumor Cells, Cultured | 1996 |
Cheminformatic models to predict binding affinities to human serum albumin.
Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids | 2001 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
Analysis of physico-chemical properties of substrates of ABC and MFS multidrug transporters of pathogenic Candida albicans.
Topics: Candida albicans; Membrane Transport Proteins; Saccharomyces cerevisiae; Structure-Activity Relationship; Substrate Specificity | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Synthesis, biological evaluation, and molecular docking study of 3-(3'-heteroatom substituted-2'-hydroxy-1'-propyloxy) xanthone analogues as novel topoisomerase IIα catalytic inhibitor.
Topics: Antigens, Neoplasm; Antineoplastic Agents; Biocatalysis; Cell Line, Tumor; Cell Survival; DNA Topoisomerases, Type II; DNA-Binding Proteins; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; HeLa Cells; HL-60 Cells; Humans; Models, Molecular; Molecular Structure; Stereoisomerism; Structure-Activity Relationship; Topoisomerase II Inhibitors; Xanthones | 2011 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
3-(3-Butylamino-2-hydroxy-propoxy)-1-hydroxy-xanthen-9-one acts as a topoisomerase IIα catalytic inhibitor with low DNA damage.
Topics: Antigens, Neoplasm; Antineoplastic Agents; Biocatalysis; Cell Line, Tumor; Cell Proliferation; DNA Damage; DNA Topoisomerases, Type II; DNA-Binding Proteins; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Structure-Activity Relationship; Topoisomerase II Inhibitors; Xanthones | 2013 |
Novel 2-aryl-4-(4'-hydroxyphenyl)-5H-indeno[1,2-b]pyridines as potent DNA non-intercalative topoisomerase catalytic inhibitors.
Topics: Antigens, Neoplasm; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; DNA; DNA Topoisomerases, Type II; DNA-Binding Proteins; Humans; Molecular Docking Simulation; Pyridines; Structure-Activity Relationship; Topoisomerase II Inhibitors | 2017 |
New N-phenylpyrrolamide DNA gyrase B inhibitors: Optimization of efficacy and antibacterial activity.
Topics: Amides; Anti-Bacterial Agents; DNA Gyrase; Dose-Response Relationship, Drug; Enterococcus faecalis; Escherichia coli; Microbial Sensitivity Tests; Molecular Structure; Pyrroles; Staphylococcus aureus; Structure-Activity Relationship; Topoisomerase II Inhibitors | 2018 |
An optimised series of substituted N-phenylpyrrolamides as DNA gyrase B inhibitors.
Topics: Amides; Anti-Bacterial Agents; DNA Gyrase; DNA Topoisomerase IV; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Pyrrolidines; Topoisomerase II Inhibitors | 2019 |
Development and characterization of a WEHI-3B D+ monomyelocytic leukemia cell line resistant to novobiocin and cross-resistant to other topoisomerase II-targeted drugs.
Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; Cell Cycle; DNA Topoisomerases, Type II; DNA, Neoplasm; Drug Resistance; Etoposide; Leukemia, Experimental; Leukemia, Myelomonocytic, Acute; Mice; Novobiocin; Topoisomerase II Inhibitors; Tritium; Tumor Cells, Cultured | 1992 |
The effect of topoisomerase inhibitors on the expression of differentiation markers and cell cycle progression in human K-562 leukemia cells.
Topics: Amsacrine; Aphidicolin; Cell Cycle; Cell Differentiation; Cycloheximide; Deoxyadenosines; Dose-Response Relationship, Drug; Etoposide; G2 Phase; Hemoglobins; Humans; Kinetics; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Melanins; Mitosis; Novobiocin; Teniposide; Topoisomerase II Inhibitors; Tumor Cells, Cultured | 1992 |
Novobiocin-induced accumulation of etoposide (VP-16) in WEHI-3B D+ leukemia cells.
Topics: Animals; Biological Transport, Active; DNA Topoisomerases, Type II; Drug Interactions; Etoposide; Leukemia, Experimental; Mice; Novobiocin; Topoisomerase II Inhibitors; Tumor Cells, Cultured | 1992 |
Potentiation by novobiocin of the cytotoxic activity of etoposide (VP-16) and teniposide (VM-26).
Topics: Adenocarcinoma; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cell Survival; DNA; DNA Topoisomerases, Type II; Drug Synergism; Etoposide; Humans; Leukemia; Lung Neoplasms; Novobiocin; RNA; Teniposide; Topoisomerase II Inhibitors; Tumor Cells, Cultured | 1992 |
Differentiation of human promonocytic leukemia U-937 cells with DNA topoisomerase II inhibitors: induction of vimentin gene expression.
Topics: Amsacrine; Antigens, Differentiation; Cell Differentiation; Cell Division; Etoposide; Gene Expression Regulation, Leukemic; Humans; Leukemia, Monocytic, Acute; Novobiocin; Oxygen; Topoisomerase II Inhibitors; Tumor Cells, Cultured; Vimentin | 1991 |
Novobiocin inhibits the repair of potentially lethal damage but not the repair of sublethal damage.
Topics: Amsacrine; Animals; Cell Line; Cricetinae; DNA Damage; DNA Repair; Etoposide; Novobiocin; Teniposide; Topoisomerase II Inhibitors | 1990 |
Effect of topoisomerase modulators on cisplatin cytotoxicity in human ovarian carcinoma cells.
Topics: Antibiotics, Antineoplastic; Camptothecin; Cell Line; Cisplatin; DNA Topoisomerases, Type I; Drug Interactions; Etoposide; Female; Humans; Naphthoquinones; Novobiocin; Ovarian Neoplasms; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Tumor Cells, Cultured | 1990 |
Comparative effects of growth inhibitors on DNA replication, DNA repair, and protein synthesis in human epidermal keratinocytes.
Topics: Anthralin; Aphidicolin; Cells, Cultured; Diterpenes; DNA Repair; DNA Replication; Etoposide; Growth Inhibitors; Humans; Keratins; Molecular Weight; Nalidixic Acid; Novobiocin; Protein Biosynthesis; Skin; Skin Diseases; Topoisomerase II Inhibitors | 1986 |
Novobiocin, nalidixic acid, etoposide, and 4'-(9-acridinylamino)methanesulfon-m-anisidide effects on G2 and mitotic Chinese hamster ovary cell progression.
Topics: Amsacrine; Animals; Cell Line; Cell Survival; DNA Damage; Etoposide; Interphase; Metaphase; Mitosis; Nalidixic Acid; Novobiocin; RNA; Topoisomerase II Inhibitors | 1989 |
Topoisomerase II: a potential target for novel antifungal agents.
Topics: Amiloride; Amsacrine; Antifungal Agents; DNA, Superhelical; Etoposide; Molecular Structure; Novobiocin; Plasmids; Podophyllotoxin; Saccharomyces cerevisiae; Structure-Activity Relationship; Topoisomerase II Inhibitors | 1989 |
Ciprofloxacin and etoposide (VP16) produce a similar pattern of DNA cleavage in a plasmid of an archaebacterium.
Topics: Ciprofloxacin; DNA Damage; Etoposide; Halobacterium; Novobiocin; Plasmids | 1989 |
Action of etoposide (VP-16-123) on human cells: no evidence for topoisomerase II involvement in excision repair of u.v.-induced DNA damage, nor for mitochondrial hypersensitivity in ataxia telangiectasia.
Topics: Ataxia Telangiectasia; Cell Survival; Cells, Cultured; Chromosomes; DNA; DNA Damage; DNA Repair; DNA Topoisomerases, Type II; Etoposide; Humans; Mitochondria; Novobiocin; Ultraviolet Rays | 1987 |
Topoisomerase inhibitors induce irreversible fragmentation of replicated DNA in concanavalin A stimulated splenocytes.
Topics: Animals; Camptothecin; Concanavalin A; DNA; DNA Replication; DNA Topoisomerases, Type II; Etoposide; Lymphocyte Activation; Lymphocytes; Mice; Mice, Inbred C57BL; Novobiocin; Phenylmethylsulfonyl Fluoride; Spleen; Sulfones; Topoisomerase II Inhibitors | 1988 |
Topoisomerase-II-mediated lesions in nascent DNA: comparison of the effects of epipodophyllotoxin derivatives, VM-26 and VP-16, and 9-anilinoacridine derivatives, m-AMSA and o-AMSA.
Topics: Adenosine Triphosphate; Amsacrine; Animals; Cross-Linking Reagents; DNA; DNA Damage; DNA Replication; DNA Topoisomerases, Type II; DNA, Neoplasm; Etoposide; Leukemia L1210; Mice; Novobiocin; Podophyllotoxin; Teniposide; Topoisomerase II Inhibitors | 1988 |
Inhibitors of DNA topoisomerase II induce topological changes in an archaebacterial plasmid in vivo.
Topics: Archaea; Bacteria; DNA, Bacterial; DNA, Superhelical; Etoposide; Novobiocin; Nucleic Acid Conformation; Plasmids; Topoisomerase II Inhibitors | 1988 |
Identification of DNA topoisomerase II as an intracellular target of antitumor epipodophyllotoxins in simian virus 40-infected monkey cells.
Topics: Animals; Cells, Cultured; Chemical Precipitation; DNA Topoisomerases, Type II; DNA, Viral; Etoposide; Haplorhini; Novobiocin; Podophyllotoxin; Simian virus 40; Teniposide | 1985 |
5,6-Dichloro-1-beta-O-ribofuranosylbenzimidazole induces DNA damage by interfering with DNA topoisomerase II.
Topics: Aphidicolin; Cells, Cultured; Chemical Precipitation; Dichlororibofuranosylbenzimidazole; Diterpenes; DNA; Electrophoresis, Agar Gel; Etoposide; Humans; Novobiocin; Proteins; Ribonucleosides; Teniposide; Topoisomerase II Inhibitors | 1987 |
Inhibitors of topoisomerase II prevent cytokine-induced expression of vascular cell adhesion molecule-1, while augmenting the expression of endothelial leukocyte adhesion molecule-1 on human umbilical vein endothelial cells.
Topics: Base Sequence; Cell Adhesion Molecules; Cells, Cultured; DNA; E-Selectin; Endothelium, Vascular; Etoposide; Gene Expression Regulation; Humans; Molecular Sequence Data; Nalidixic Acid; Novobiocin; Protein Biosynthesis; Protein Kinase C; RNA, Messenger; Topoisomerase II Inhibitors; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1 | 1993 |
Increased rate of adenosine triphosphate-dependent etoposide (VP-16) efflux in a murine leukemia cell line overexpressing the multidrug resistance-associated protein (MRP) gene.
Topics: Adenosine Triphosphate; Antineoplastic Agents, Phytogenic; Base Sequence; Biological Transport; DNA Topoisomerases, Type II; Drug Resistance, Multiple; Etoposide; Immunoblotting; Leukemia, Experimental; Molecular Sequence Data; Novobiocin; Nuclear Matrix; Tumor Cells, Cultured | 1995 |
CP-115,953 stimulates cytokine production by lymphocytes.
Topics: Anti-Infective Agents; Cells, Cultured; Cytokines; DNA Damage; Etoposide; Fluoroquinolones; Humans; Interferon-gamma; Interleukin-2; Lymphocyte Activation; Novobiocin; Quinolones; RNA, Messenger; T-Lymphocytes; Thymidine; Topoisomerase II Inhibitors | 1995 |
Antifolates can potentiate topoisomerase II inhibitors in vitro and in vivo.
Topics: Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Division; Cell Line; Cell Survival; DNA Damage; DNA, Neoplasm; Drug Synergism; Etoposide; Folic Acid Antagonists; Head and Neck Neoplasms; Humans; Male; Methotrexate; Mice; Mice, Inbred C3H; Novobiocin; Ornithine; Pterins; Topoisomerase II Inhibitors; Trimetrexate; Tumor Cells, Cultured | 1995 |
Active dissociation of Hoechst 33342 from DNA in living mammalian cells.
Topics: Benzimidazoles; DNA; Ellipticines; Etoposide; Fluorescence; HeLa Cells; Humans; Novobiocin; Topoisomerase II Inhibitors | 1995 |
Reversal of etoposide resistance in non-P-glycoprotein expressing multidrug resistant tumor cell lines by novobiocin.
Topics: Adenocarcinoma; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carrier Proteins; Colonic Neoplasms; DNA Topoisomerases, Type II; DNA, Neoplasm; Drug Resistance; Etoposide; Flow Cytometry; Humans; Leukemia L1210; Lung Neoplasms; Membrane Glycoproteins; Mice; Novobiocin; Tumor Cells, Cultured | 1993 |
Phorbol ester induces apoptosis in HL-60 promyelocytic leukemia cells but not in HL-60 PET mutant.
Topics: Apoptosis; Calcimycin; DNA Damage; DNA, Neoplasm; Drug Tolerance; Etoposide; Humans; Leukemia, Promyelocytic, Acute; Mutation; Novobiocin; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Effects of topoisomerase II-targeted drugs on enzyme-mediated DNA cleavage and ATP hydrolysis: evidence for distinct drug interaction domains on topoisomerase II.
Topics: Adenosine Triphosphate; Amsacrine; Animals; Anti-Infective Agents; Antineoplastic Agents; Binding Sites; Cell Nucleus; DNA Topoisomerases, Type II; DNA, Bacterial; Drosophila melanogaster; Escherichia coli; Etoposide; Fluoroquinolones; Genistein; Hydrolysis; Isoflavones; Novobiocin; Plasmids; Quercetin; Quinolones; Topoisomerase II Inhibitors | 1993 |
Exploiting mechanistic differences between drug classes to define functional drug interaction domains on topoisomerase II. Evidence that several diverse DNA cleavage-enhancing agents share a common site of action on the enzyme.
Topics: Amsacrine; Animals; Anti-Infective Agents; Binding Sites; Cell Line; Cell Nucleus; DNA; DNA Topoisomerases, Type II; DNA, Superhelical; Drosophila melanogaster; Drug Interactions; Etoposide; Fluoroquinolones; Genistein; Growth Inhibitors; Isoflavones; Kinetics; Novobiocin; Protein Binding; Quinolones; Structure-Activity Relationship; Topoisomerase II Inhibitors | 1993 |
Genistein induces apoptosis in immature human thymocytes by inhibiting topoisomerase-II.
Topics: Apoptosis; Benzoquinones; Cells, Cultured; Chromatin; DNA Damage; Etoposide; Genistein; Humans; Immunophenotyping; Infant; Isoflavones; Kinetics; Lactams, Macrocyclic; Methylprednisolone; Novobiocin; Phorbol 12,13-Dibutyrate; Protein-Tyrosine Kinases; Quinones; Rifabutin; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thymus Gland; Time Factors; Topoisomerase II Inhibitors | 1993 |
Method for quantifying expression of functionally active topoisomerase II in patients with leukaemia.
Topics: Adolescent; Adult; Aged; Animals; Biochemistry; Blastomeres; Crithidia fasciculata; DNA Topoisomerases, Type II; DNA, Kinetoplast; Doxorubicin; Ellipticines; Ethylmaleimide; Etoposide; Female; Humans; Male; Middle Aged; Novobiocin; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Sensitivity and Specificity; Topoisomerase II Inhibitors | 1996 |
Inhibition of DNA unwinding and ATPase activities of human DNA helicase II by chemotherapeutic agents.
Topics: Adenosine Triphosphatases; Amsacrine; Antineoplastic Agents; Aphidicolin; Camptothecin; Dactinomycin; Daunorubicin; DNA; DNA Helicases; Ellipticines; Enzyme Inhibitors; Ethidium; Etoposide; Genistein; Humans; Isoflavones; Nogalamycin; Novobiocin; Topoisomerase I Inhibitors | 1997 |
Inhibition of pea chloroplast DNA helicase unwinding and ATPase activities by DNA-interacting ligands.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Amsacrine; Camptothecin; Chloroplasts; Dactinomycin; Daunorubicin; DNA Helicases; Ellipticines; Ethidium; Etoposide; Genistein; Hydrolysis; Intercalating Agents; Ligands; Nogalamycin; Novobiocin; Pisum sativum | 1998 |
Novobiocin-induced VP-16 accumulation and MRP expression in human leukemia and ovarian carcinoma cells.
Topics: Ascites; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Biological Transport; Bone Marrow; Etoposide; Female; Humans; Kinetics; Leukemia; Multidrug Resistance-Associated Proteins; Novobiocin; Ovarian Neoplasms; Tumor Cells, Cultured | 2000 |
Structure-activity studies of novobiocin analogs as modulators of the cytotoxicity of etoposide (VP-16).
Topics: Adenosine Triphosphate; Antineoplastic Agents, Phytogenic; ATP-Binding Cassette Transporters; Drug Synergism; Enzyme Inhibitors; Etoposide; Humans; Multidrug Resistance-Associated Proteins; Novobiocin; Structure-Activity Relationship; Topoisomerase II Inhibitors; Tumor Cells, Cultured | 2000 |
The effect of topoisomerase II inhibitors on the kinetoplast ultrastructure.
Topics: Animals; DNA Replication; DNA Topoisomerases, Type II; DNA, Kinetoplast; Enzyme Inhibitors; Etoposide; Nalidixic Acid; Novobiocin; Parasitic Sensitivity Tests; Topoisomerase II Inhibitors; Trypanocidal Agents; Trypanosomatina | 2004 |
Transcriptional responses of Bacillus subtillis and thuringiensis to antibiotics and anti-tumour drugs.
Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Bacillus subtilis; Bacillus thuringiensis; Ciprofloxacin; DNA; DNA Gyrase; Etoposide; Gene Expression Regulation; Novobiocin; Plasmids; SOS Response, Genetics; Transcription, Genetic | 2009 |
Inhibition of unwinding and ATPase activities of pea MCM6 DNA helicase by actinomycin and nogalamycin.
Topics: Adenosine Triphosphatases; Camptothecin; Cisplatin; Dactinomycin; Daunorubicin; DNA Helicases; Ellipticines; Enzyme Inhibitors; Etoposide; Intercalating Agents; Mitoxantrone; Nogalamycin; Novobiocin; Pisum sativum; Plant Proteins | 2011 |