Page last updated: 2024-08-23

etoposide and novobiocin

etoposide has been researched along with novobiocin in 51 studies

Research

Studies (51)

Timeframe	Studies, this research(%)	All Research%
pre-1990	10 (19.61)	18.7374
1990's	22 (43.14)	18.2507
2000's	7 (13.73)	29.6817
2010's	12 (23.53)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Hansch, C; Khwaja, TA; Selassie, CD	1
Barrows, LR; Ireland, CM; Kokoshka, JM	1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Benet, LZ; Brouwer, KL; Chu, X; Dahlin, A; Evers, R; Fischer, V; Giacomini, KM; Hillgren, KM; Hoffmaster, KA; Huang, SM; Ishikawa, T; Keppler, D; Kim, RB; Lee, CA; Niemi, M; Polli, JW; Sugiyama, Y; Swaan, PW; Tweedie, DJ; Ware, JA; Wright, SH; Yee, SW; Zamek-Gliszczynski, MJ; Zhang, L	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ghosh, I; Manoharlal, R; Prakash, O; Prasad, R; Puri, N; Sharma, M	1
Ekins, S; Williams, AJ; Xu, JJ	1
Jun, KY; Jung, MJ; Kwon, Y; Lee, ES; Lee, EY; Lee, OH; Na, Y; Park Choo, HY	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Chang, IH; Jun, KY; Kwon, Y; Lee, E; Lee, ES; Na, Y; Park, SE	1
Bist, G; Jun, KY; Kadayat, TM; Kwon, Y; Lee, ES; Park, S; Shrestha, A; Thapa Magar, TB	1
Benedetto Tiz, D; Draskovits, G; Durante Cruz, C; Durcik, M; Ilaš, J; Kikelj, D; Lovison, D; Nyerges, Á; Pál, C; Peterlin Mašič, L; Skok, Ž; Tammela, P; Tomašič, T; Zidar, N	1
Cruz, CD; Draskovits, G; Durcik, M; Ilaš, J; Kikelj, D; Mašič, LP; Nyerges, Á; Pál, C; Révész, T; Skok, Ž; Tammela, P; Tiz, DB; Tomašič, T; Zega, A; Zidar, N; Žigon, D	1
Lorico, A; Rappa, G; Sartorelli, AC	4
Constantinou, A; Grdina, D; Huberman, E; Kiguchi, K	1
Aller, P; Bernabeu, C; Cabañas, C; Mata, F; Rius, C; Zorrilla, AR	1
Elkind, MM; Shibuya, ML; Utsumi, H	1
Andrews, PA; Howell, SB; Katz, EJ; Kling, KM; Vick, JS	1
Bohr, V; Hanawalt, P; Mansbridge, J	1
Kort, L; Rowley, R	1
Denyer, SP; Dewick, PM; Figgitt, DP; Jackson, DE; Williams, P	1
Forterre, P; Sioud, M	1
Downes, CS; Johnson, RT; Mullinger, AM	1
Duguet, M; Jaxel, C; Mirambeau, G; Panijel, J; Portemer, C; Taudou, G	1
Beerman, TA; Sigmund, RD; Woynarowski, JM	1
Baldacci, G; de Recondo, AM; Forterre, P; Sioud, M	1
Liu, LF; Rowe, TC; Yang, L	1
Lönn, S; Lönn, U	1
Deisher, TA; Harlan, JM; Kaushansky, K	1
Catapano, CV; Fernandes, DJ; Germino, JF; Lorico, A; Rappa, G; Sartorelli, AC; Srimatkandada, S	1
Forsgren, A; Riesbeck, K	1
Holden, SA; Northey, D; Robinson, MF; Rosowsky, A; Teicher, BA	1
Filatov, MV; Varfolomeeva, EY	1
Macfarlane, DE; O'Donnell, PS	1
Corbett, AH; Osheroff, N; Robinson, MJ	1
Corbett, AH; Hong, D; Osheroff, N	1
McCabe, MJ; Orrenius, S	1
Cattan, AR; Douglas, EA; Levett, D; Middleton, PG; Taylor, PR	1
Falaschi, A; Ochem, A; Phan, TN; Tuteja, N; Tuteja, R	1
Phan, TN; Tuteja, N	1
Johnson, LM; Lorico, A; Murren, JR; Rappa, G; Sartorelli, AC	1
Fodstad, O; Lorico, A; Rappa, G; Sartorelli, AC; Shyam, K	1
Cavalcanti, DP; de Souza, W; Fragoso, SP; Goldenberg, S; Motta, MC	1
Boudabous, A; Cekaite, L; Sioud, M	1
Pham, XH; Tran, NQ; Tuteja, N; Tuteja, R	1

Reviews

1 review(s) available for etoposide and novobiocin

Article	Year
Membrane transporters in drug development. Nature reviews. Drug discovery, 2010, Volume: 9, Issue:3 Topics: Animals; Computer Simulation; Decision Trees; Drug Approval; Drug Discovery; Drug Evaluation, Preclinical; Drug Interactions; Humans; Membrane Transport Proteins; Mice; Mice, Knockout; Prescription Drugs	2010

Other Studies

50 other study(ies) available for etoposide and novobiocin

Article	Year
Structure-activity relationships of antineoplastic agents in multidrug resistance. Journal of medicinal chemistry, 1990, Volume: 33, Issue:7 Topics: Animals; Antineoplastic Agents; Cell Line; Cell Survival; Cricetinae; Dactinomycin; Drug Resistance; Leukemia L1210; Mice; Regression Analysis; Structure-Activity Relationship; Tumor Cells, Cultured	1990
Cell-based screen for identification of inhibitors of tubulin polymerization. Journal of natural products, 1996, Volume: 59, Issue:12 Topics: Animals; Brain Neoplasms; Bucladesine; Cell Differentiation; Drug Screening Assays, Antitumor; Formazans; Glioma; Rats; Tubulin; Tumor Cells, Cultured	1996
Cheminformatic models to predict binding affinities to human serum albumin. Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25 Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids	2001
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
Analysis of physico-chemical properties of substrates of ABC and MFS multidrug transporters of pathogenic Candida albicans. European journal of medicinal chemistry, 2010, Volume: 45, Issue:11 Topics: Candida albicans; Membrane Transport Proteins; Saccharomyces cerevisiae; Structure-Activity Relationship; Substrate Specificity	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Synthesis, biological evaluation, and molecular docking study of 3-(3'-heteroatom substituted-2'-hydroxy-1'-propyloxy) xanthone analogues as novel topoisomerase IIα catalytic inhibitor. European journal of medicinal chemistry, 2011, Volume: 46, Issue:6 Topics: Antigens, Neoplasm; Antineoplastic Agents; Biocatalysis; Cell Line, Tumor; Cell Survival; DNA Topoisomerases, Type II; DNA-Binding Proteins; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; HeLa Cells; HL-60 Cells; Humans; Models, Molecular; Molecular Structure; Stereoisomerism; Structure-Activity Relationship; Topoisomerase II Inhibitors; Xanthones	2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
3-(3-Butylamino-2-hydroxy-propoxy)-1-hydroxy-xanthen-9-one acts as a topoisomerase IIα catalytic inhibitor with low DNA damage. European journal of medicinal chemistry, 2013, Volume: 69 Topics: Antigens, Neoplasm; Antineoplastic Agents; Biocatalysis; Cell Line, Tumor; Cell Proliferation; DNA Damage; DNA Topoisomerases, Type II; DNA-Binding Proteins; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Structure-Activity Relationship; Topoisomerase II Inhibitors; Xanthones	2013
Novel 2-aryl-4-(4'-hydroxyphenyl)-5H-indeno[1,2-b]pyridines as potent DNA non-intercalative topoisomerase catalytic inhibitors. European journal of medicinal chemistry, 2017, Jan-05, Volume: 125 Topics: Antigens, Neoplasm; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; DNA; DNA Topoisomerases, Type II; DNA-Binding Proteins; Humans; Molecular Docking Simulation; Pyridines; Structure-Activity Relationship; Topoisomerase II Inhibitors	2017
New N-phenylpyrrolamide DNA gyrase B inhibitors: Optimization of efficacy and antibacterial activity. European journal of medicinal chemistry, 2018, Jun-25, Volume: 154 Topics: Amides; Anti-Bacterial Agents; DNA Gyrase; Dose-Response Relationship, Drug; Enterococcus faecalis; Escherichia coli; Microbial Sensitivity Tests; Molecular Structure; Pyrroles; Staphylococcus aureus; Structure-Activity Relationship; Topoisomerase II Inhibitors	2018
An optimised series of substituted N-phenylpyrrolamides as DNA gyrase B inhibitors. European journal of medicinal chemistry, 2019, Apr-01, Volume: 167 Topics: Amides; Anti-Bacterial Agents; DNA Gyrase; DNA Topoisomerase IV; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Pyrrolidines; Topoisomerase II Inhibitors	2019
Development and characterization of a WEHI-3B D+ monomyelocytic leukemia cell line resistant to novobiocin and cross-resistant to other topoisomerase II-targeted drugs. Cancer research, 1992, May-15, Volume: 52, Issue:10 Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; Cell Cycle; DNA Topoisomerases, Type II; DNA, Neoplasm; Drug Resistance; Etoposide; Leukemia, Experimental; Leukemia, Myelomonocytic, Acute; Mice; Novobiocin; Topoisomerase II Inhibitors; Tritium; Tumor Cells, Cultured	1992
The effect of topoisomerase inhibitors on the expression of differentiation markers and cell cycle progression in human K-562 leukemia cells. Experimental cell research, 1992, Volume: 203, Issue:1 Topics: Amsacrine; Aphidicolin; Cell Cycle; Cell Differentiation; Cycloheximide; Deoxyadenosines; Dose-Response Relationship, Drug; Etoposide; G2 Phase; Hemoglobins; Humans; Kinetics; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Melanins; Mitosis; Novobiocin; Teniposide; Topoisomerase II Inhibitors; Tumor Cells, Cultured	1992
Novobiocin-induced accumulation of etoposide (VP-16) in WEHI-3B D+ leukemia cells. International journal of cancer, 1992, Dec-02, Volume: 52, Issue:6 Topics: Animals; Biological Transport, Active; DNA Topoisomerases, Type II; Drug Interactions; Etoposide; Leukemia, Experimental; Mice; Novobiocin; Topoisomerase II Inhibitors; Tumor Cells, Cultured	1992
Potentiation by novobiocin of the cytotoxic activity of etoposide (VP-16) and teniposide (VM-26). International journal of cancer, 1992, Jul-09, Volume: 51, Issue:5 Topics: Adenocarcinoma; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cell Survival; DNA; DNA Topoisomerases, Type II; Drug Synergism; Etoposide; Humans; Leukemia; Lung Neoplasms; Novobiocin; RNA; Teniposide; Topoisomerase II Inhibitors; Tumor Cells, Cultured	1992
Differentiation of human promonocytic leukemia U-937 cells with DNA topoisomerase II inhibitors: induction of vimentin gene expression. Molecular pharmacology, 1991, Volume: 39, Issue:4 Topics: Amsacrine; Antigens, Differentiation; Cell Differentiation; Cell Division; Etoposide; Gene Expression Regulation, Leukemic; Humans; Leukemia, Monocytic, Acute; Novobiocin; Oxygen; Topoisomerase II Inhibitors; Tumor Cells, Cultured; Vimentin	1991
Novobiocin inhibits the repair of potentially lethal damage but not the repair of sublethal damage. Radiation research, 1990, Volume: 123, Issue:1 Topics: Amsacrine; Animals; Cell Line; Cricetinae; DNA Damage; DNA Repair; Etoposide; Novobiocin; Teniposide; Topoisomerase II Inhibitors	1990
Effect of topoisomerase modulators on cisplatin cytotoxicity in human ovarian carcinoma cells. European journal of cancer (Oxford, England : 1990), 1990, Volume: 26, Issue:6 Topics: Antibiotics, Antineoplastic; Camptothecin; Cell Line; Cisplatin; DNA Topoisomerases, Type I; Drug Interactions; Etoposide; Female; Humans; Naphthoquinones; Novobiocin; Ovarian Neoplasms; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Tumor Cells, Cultured	1990
Comparative effects of growth inhibitors on DNA replication, DNA repair, and protein synthesis in human epidermal keratinocytes. Cancer research, 1986, Volume: 46, Issue:6 Topics: Anthralin; Aphidicolin; Cells, Cultured; Diterpenes; DNA Repair; DNA Replication; Etoposide; Growth Inhibitors; Humans; Keratins; Molecular Weight; Nalidixic Acid; Novobiocin; Protein Biosynthesis; Skin; Skin Diseases; Topoisomerase II Inhibitors	1986
Novobiocin, nalidixic acid, etoposide, and 4'-(9-acridinylamino)methanesulfon-m-anisidide effects on G2 and mitotic Chinese hamster ovary cell progression. Cancer research, 1989, Sep-01, Volume: 49, Issue:17 Topics: Amsacrine; Animals; Cell Line; Cell Survival; DNA Damage; Etoposide; Interphase; Metaphase; Mitosis; Nalidixic Acid; Novobiocin; RNA; Topoisomerase II Inhibitors	1989
Topoisomerase II: a potential target for novel antifungal agents. Biochemical and biophysical research communications, 1989, Apr-14, Volume: 160, Issue:1 Topics: Amiloride; Amsacrine; Antifungal Agents; DNA, Superhelical; Etoposide; Molecular Structure; Novobiocin; Plasmids; Podophyllotoxin; Saccharomyces cerevisiae; Structure-Activity Relationship; Topoisomerase II Inhibitors	1989
Ciprofloxacin and etoposide (VP16) produce a similar pattern of DNA cleavage in a plasmid of an archaebacterium. Biochemistry, 1989, May-02, Volume: 28, Issue:9 Topics: Ciprofloxacin; DNA Damage; Etoposide; Halobacterium; Novobiocin; Plasmids	1989
Action of etoposide (VP-16-123) on human cells: no evidence for topoisomerase II involvement in excision repair of u.v.-induced DNA damage, nor for mitochondrial hypersensitivity in ataxia telangiectasia. Carcinogenesis, 1987, Volume: 8, Issue:11 Topics: Ataxia Telangiectasia; Cell Survival; Cells, Cultured; Chromosomes; DNA; DNA Damage; DNA Repair; DNA Topoisomerases, Type II; Etoposide; Humans; Mitochondria; Novobiocin; Ultraviolet Rays	1987
Topoisomerase inhibitors induce irreversible fragmentation of replicated DNA in concanavalin A stimulated splenocytes. Biochemistry, 1988, Jan-12, Volume: 27, Issue:1 Topics: Animals; Camptothecin; Concanavalin A; DNA; DNA Replication; DNA Topoisomerases, Type II; Etoposide; Lymphocyte Activation; Lymphocytes; Mice; Mice, Inbred C57BL; Novobiocin; Phenylmethylsulfonyl Fluoride; Spleen; Sulfones; Topoisomerase II Inhibitors	1988
Topoisomerase-II-mediated lesions in nascent DNA: comparison of the effects of epipodophyllotoxin derivatives, VM-26 and VP-16, and 9-anilinoacridine derivatives, m-AMSA and o-AMSA. Biochimica et biophysica acta, 1988, May-06, Volume: 950, Issue:1 Topics: Adenosine Triphosphate; Amsacrine; Animals; Cross-Linking Reagents; DNA; DNA Damage; DNA Replication; DNA Topoisomerases, Type II; DNA, Neoplasm; Etoposide; Leukemia L1210; Mice; Novobiocin; Podophyllotoxin; Teniposide; Topoisomerase II Inhibitors	1988
Inhibitors of DNA topoisomerase II induce topological changes in an archaebacterial plasmid in vivo. Biochemical pharmacology, 1988, May-01, Volume: 37, Issue:9 Topics: Archaea; Bacteria; DNA, Bacterial; DNA, Superhelical; Etoposide; Novobiocin; Nucleic Acid Conformation; Plasmids; Topoisomerase II Inhibitors	1988
Identification of DNA topoisomerase II as an intracellular target of antitumor epipodophyllotoxins in simian virus 40-infected monkey cells. Cancer research, 1985, Volume: 45, Issue:11 Pt 2 Topics: Animals; Cells, Cultured; Chemical Precipitation; DNA Topoisomerases, Type II; DNA, Viral; Etoposide; Haplorhini; Novobiocin; Podophyllotoxin; Simian virus 40; Teniposide	1985
5,6-Dichloro-1-beta-O-ribofuranosylbenzimidazole induces DNA damage by interfering with DNA topoisomerase II. European journal of biochemistry, 1987, May-04, Volume: 164, Issue:3 Topics: Aphidicolin; Cells, Cultured; Chemical Precipitation; Dichlororibofuranosylbenzimidazole; Diterpenes; DNA; Electrophoresis, Agar Gel; Etoposide; Humans; Novobiocin; Proteins; Ribonucleosides; Teniposide; Topoisomerase II Inhibitors	1987
Inhibitors of topoisomerase II prevent cytokine-induced expression of vascular cell adhesion molecule-1, while augmenting the expression of endothelial leukocyte adhesion molecule-1 on human umbilical vein endothelial cells. Cell adhesion and communication, 1993, Volume: 1, Issue:2 Topics: Base Sequence; Cell Adhesion Molecules; Cells, Cultured; DNA; E-Selectin; Endothelium, Vascular; Etoposide; Gene Expression Regulation; Humans; Molecular Sequence Data; Nalidixic Acid; Novobiocin; Protein Biosynthesis; Protein Kinase C; RNA, Messenger; Topoisomerase II Inhibitors; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1	1993
Increased rate of adenosine triphosphate-dependent etoposide (VP-16) efflux in a murine leukemia cell line overexpressing the multidrug resistance-associated protein (MRP) gene. Cancer research, 1995, Oct-01, Volume: 55, Issue:19 Topics: Adenosine Triphosphate; Antineoplastic Agents, Phytogenic; Base Sequence; Biological Transport; DNA Topoisomerases, Type II; Drug Resistance, Multiple; Etoposide; Immunoblotting; Leukemia, Experimental; Molecular Sequence Data; Novobiocin; Nuclear Matrix; Tumor Cells, Cultured	1995
CP-115,953 stimulates cytokine production by lymphocytes. Antimicrobial agents and chemotherapy, 1995, Volume: 39, Issue:2 Topics: Anti-Infective Agents; Cells, Cultured; Cytokines; DNA Damage; Etoposide; Fluoroquinolones; Humans; Interferon-gamma; Interleukin-2; Lymphocyte Activation; Novobiocin; Quinolones; RNA, Messenger; T-Lymphocytes; Thymidine; Topoisomerase II Inhibitors	1995
Antifolates can potentiate topoisomerase II inhibitors in vitro and in vivo. Cancer chemotherapy and pharmacology, 1995, Volume: 36, Issue:2 Topics: Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Division; Cell Line; Cell Survival; DNA Damage; DNA, Neoplasm; Drug Synergism; Etoposide; Folic Acid Antagonists; Head and Neck Neoplasms; Humans; Male; Methotrexate; Mice; Mice, Inbred C3H; Novobiocin; Ornithine; Pterins; Topoisomerase II Inhibitors; Trimetrexate; Tumor Cells, Cultured	1995
Active dissociation of Hoechst 33342 from DNA in living mammalian cells. Mutation research, 1995, Volume: 327, Issue:1-2 Topics: Benzimidazoles; DNA; Ellipticines; Etoposide; Fluorescence; HeLa Cells; Humans; Novobiocin; Topoisomerase II Inhibitors	1995
Reversal of etoposide resistance in non-P-glycoprotein expressing multidrug resistant tumor cell lines by novobiocin. Cancer research, 1993, Nov-15, Volume: 53, Issue:22 Topics: Adenocarcinoma; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carrier Proteins; Colonic Neoplasms; DNA Topoisomerases, Type II; DNA, Neoplasm; Drug Resistance; Etoposide; Flow Cytometry; Humans; Leukemia L1210; Lung Neoplasms; Membrane Glycoproteins; Mice; Novobiocin; Tumor Cells, Cultured	1993
Phorbol ester induces apoptosis in HL-60 promyelocytic leukemia cells but not in HL-60 PET mutant. Leukemia, 1993, Volume: 7, Issue:11 Topics: Apoptosis; Calcimycin; DNA Damage; DNA, Neoplasm; Drug Tolerance; Etoposide; Humans; Leukemia, Promyelocytic, Acute; Mutation; Novobiocin; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured	1993
Effects of topoisomerase II-targeted drugs on enzyme-mediated DNA cleavage and ATP hydrolysis: evidence for distinct drug interaction domains on topoisomerase II. Biochemistry, 1993, Apr-13, Volume: 32, Issue:14 Topics: Adenosine Triphosphate; Amsacrine; Animals; Anti-Infective Agents; Antineoplastic Agents; Binding Sites; Cell Nucleus; DNA Topoisomerases, Type II; DNA, Bacterial; Drosophila melanogaster; Escherichia coli; Etoposide; Fluoroquinolones; Genistein; Hydrolysis; Isoflavones; Novobiocin; Plasmids; Quercetin; Quinolones; Topoisomerase II Inhibitors	1993
Exploiting mechanistic differences between drug classes to define functional drug interaction domains on topoisomerase II. Evidence that several diverse DNA cleavage-enhancing agents share a common site of action on the enzyme. The Journal of biological chemistry, 1993, Jul-05, Volume: 268, Issue:19 Topics: Amsacrine; Animals; Anti-Infective Agents; Binding Sites; Cell Line; Cell Nucleus; DNA; DNA Topoisomerases, Type II; DNA, Superhelical; Drosophila melanogaster; Drug Interactions; Etoposide; Fluoroquinolones; Genistein; Growth Inhibitors; Isoflavones; Kinetics; Novobiocin; Protein Binding; Quinolones; Structure-Activity Relationship; Topoisomerase II Inhibitors	1993
Genistein induces apoptosis in immature human thymocytes by inhibiting topoisomerase-II. Biochemical and biophysical research communications, 1993, Jul-30, Volume: 194, Issue:2 Topics: Apoptosis; Benzoquinones; Cells, Cultured; Chromatin; DNA Damage; Etoposide; Genistein; Humans; Immunophenotyping; Infant; Isoflavones; Kinetics; Lactams, Macrocyclic; Methylprednisolone; Novobiocin; Phorbol 12,13-Dibutyrate; Protein-Tyrosine Kinases; Quinones; Rifabutin; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thymus Gland; Time Factors; Topoisomerase II Inhibitors	1993
Method for quantifying expression of functionally active topoisomerase II in patients with leukaemia. Journal of clinical pathology, 1996, Volume: 49, Issue:10 Topics: Adolescent; Adult; Aged; Animals; Biochemistry; Blastomeres; Crithidia fasciculata; DNA Topoisomerases, Type II; DNA, Kinetoplast; Doxorubicin; Ellipticines; Ethylmaleimide; Etoposide; Female; Humans; Male; Middle Aged; Novobiocin; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Sensitivity and Specificity; Topoisomerase II Inhibitors	1996
Inhibition of DNA unwinding and ATPase activities of human DNA helicase II by chemotherapeutic agents. Biochemical and biophysical research communications, 1997, Jul-30, Volume: 236, Issue:3 Topics: Adenosine Triphosphatases; Amsacrine; Antineoplastic Agents; Aphidicolin; Camptothecin; Dactinomycin; Daunorubicin; DNA; DNA Helicases; Ellipticines; Enzyme Inhibitors; Ethidium; Etoposide; Genistein; Humans; Isoflavones; Nogalamycin; Novobiocin; Topoisomerase I Inhibitors	1997
Inhibition of pea chloroplast DNA helicase unwinding and ATPase activities by DNA-interacting ligands. Biochemical and biophysical research communications, 1998, Mar-27, Volume: 244, Issue:3 Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Amsacrine; Camptothecin; Chloroplasts; Dactinomycin; Daunorubicin; DNA Helicases; Ellipticines; Ethidium; Etoposide; Genistein; Hydrolysis; Intercalating Agents; Ligands; Nogalamycin; Novobiocin; Pisum sativum	1998
Novobiocin-induced VP-16 accumulation and MRP expression in human leukemia and ovarian carcinoma cells. Anti-cancer drug design, 2000, Volume: 15, Issue:2 Topics: Ascites; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Biological Transport; Bone Marrow; Etoposide; Female; Humans; Kinetics; Leukemia; Multidrug Resistance-Associated Proteins; Novobiocin; Ovarian Neoplasms; Tumor Cells, Cultured	2000
Structure-activity studies of novobiocin analogs as modulators of the cytotoxicity of etoposide (VP-16). Oncology research, 2000, Volume: 12, Issue:3 Topics: Adenosine Triphosphate; Antineoplastic Agents, Phytogenic; ATP-Binding Cassette Transporters; Drug Synergism; Enzyme Inhibitors; Etoposide; Humans; Multidrug Resistance-Associated Proteins; Novobiocin; Structure-Activity Relationship; Topoisomerase II Inhibitors; Tumor Cells, Cultured	2000
The effect of topoisomerase II inhibitors on the kinetoplast ultrastructure. Parasitology research, 2004, Volume: 94, Issue:6 Topics: Animals; DNA Replication; DNA Topoisomerases, Type II; DNA, Kinetoplast; Enzyme Inhibitors; Etoposide; Nalidixic Acid; Novobiocin; Parasitic Sensitivity Tests; Topoisomerase II Inhibitors; Trypanocidal Agents; Trypanosomatina	2004
Transcriptional responses of Bacillus subtillis and thuringiensis to antibiotics and anti-tumour drugs. International journal of molecular medicine, 2009, Volume: 23, Issue:1 Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Bacillus subtilis; Bacillus thuringiensis; Ciprofloxacin; DNA; DNA Gyrase; Etoposide; Gene Expression Regulation; Novobiocin; Plasmids; SOS Response, Genetics; Transcription, Genetic	2009
Inhibition of unwinding and ATPase activities of pea MCM6 DNA helicase by actinomycin and nogalamycin. Plant signaling & behavior, 2011, Volume: 6, Issue:3 Topics: Adenosine Triphosphatases; Camptothecin; Cisplatin; Dactinomycin; Daunorubicin; DNA Helicases; Ellipticines; Enzyme Inhibitors; Etoposide; Intercalating Agents; Mitoxantrone; Nogalamycin; Novobiocin; Pisum sativum; Plant Proteins	2011