Page last updated: 2024-08-23

etoposide and naphthoquinones

etoposide has been researched along with naphthoquinones in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.55)18.7374
1990's3 (13.64)18.2507
2000's10 (45.45)29.6817
2010's5 (22.73)24.3611
2020's3 (13.64)2.80

Authors

AuthorsStudies
Adamson, RH; Mead, JA; Sieber, SM1
Andrews, PA; Howell, SB; Katz, EJ; Kling, KM; Vick, JS1
Aiuchi, T; Cao, J; Hashimoto, S; Ida, Y; Masuda, Y; Miyakoshi, M; Nakajo, S; Nakaya, K; Xu, M1
Ding, J; Qing, C; Zhang, JS1
Bastow, KF; Krishnan, P1
Flynn, PM; Harrison, PL; Hughes, W; Relling, MV; Schuetz, EG; van de Poll, ME1
Ding, J; He, XX; Meng, LH; Zhang, JS1
Hara, O; Ikegami, S; Iwamatsu, T; Shibata, Y; Yamashita, M1
Ding, J; Miao, ZH; Tang, T; Zhang, JS; Zhang, YX1
Hwang, HJ; Kim, C; Kim, HJ; Lee, EJ; Lee, HJ; Lee, SK; Park, HJ; Seo, EK; Shin, SH; Suh, ME1
Aiuchi, T; Hori, K; Horie, M; Kajimoto, S; Masuda, Y; Nakajo, S; Nakaya, K; Shibayama-Imazu, T; Shima, G1
Berzins, K; Grandien, A; Hagstedt, M; Nyakeriga, AM; Perlmann, H; Perlmann, P; Troye-Blomberg, M; Zhivotovsky, B1
Cai, Y; Ding, J; Lin, L; Lu, J; Miao, Z1
Burt, HM; Higo, T; Hunter, WL; Jackson, JK1
Chandna, S; Mathur, R; N Kapoor, P; S Dwarakanath, B1
Chen, SB; Gu, LQ; Huang, SL; Huang, ZH; Huang, ZS; Li, D; Ou, JB; Ou, TM; Shen, LL; Tan, JH; Wu, WB1
Altieri, DC; Bosari, S; Faversani, A; Lopergolo, A; Moro, GP; Rivadeneira, D; Schultz, DC; Tosi, D; Vaira, V1
Huang, J; Liu, B; Lyu, H; Wang, J1
Kok, MK; Nakagawa, T; Nishimura, R; Ong, SM; Saeki, K1
Dizdar, L; Esposito, I; Ghadimi, MPH; Knoefel, WT; Krieg, A; Schlünder, PM; Vay, C1
Labbozzetta, M; Notarbartolo, M; Occhipinti, C; Poma, P; Sajeva, M1
Bolívar, J; Chinchilla, N; Durán, AG; Gutiérrez, MT; Macías, FA; Molinillo, JMG; Simonet, AM; Valdivia, MM1

Reviews

1 review(s) available for etoposide and naphthoquinones

ArticleYear
Pharmacology of antitumor agents from higher plants.
    Cancer treatment reports, 1976, Volume: 60, Issue:8

    Topics: Animals; Antineoplastic Agents, Phytogenic; Aporphines; Camptothecin; Carcinoma, Squamous Cell; Chemical Phenomena; Chemistry; Etoposide; Humans; Leukemia L1210; Leukemia, Experimental; Leukemia, Lymphoid; Maytansine; Melanoma; Naphthoquinones; Nasopharyngeal Neoplasms; Neoplasms; Neoplasms, Experimental; Phenanthrenes; Structure-Activity Relationship; Teniposide; Vinblastine; Vincristine

1976

Trials

1 trial(s) available for etoposide and naphthoquinones

ArticleYear
The effect of atovaquone on etoposide pharmacokinetics in children with acute lymphoblastic leukemia.
    Cancer chemotherapy and pharmacology, 2001, Volume: 47, Issue:6

    Topics: Adolescent; Antifungal Agents; Antineoplastic Agents, Phytogenic; Area Under Curve; Atovaquone; Child; Child, Preschool; Cross-Over Studies; Drug Interactions; Etoposide; Female; Humans; Lymphoma, Non-Hodgkin; Male; Naphthoquinones; Pilot Projects; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Trimethoprim, Sulfamethoxazole Drug Combination

2001

Other Studies

20 other study(ies) available for etoposide and naphthoquinones

ArticleYear
Effect of topoisomerase modulators on cisplatin cytotoxicity in human ovarian carcinoma cells.
    European journal of cancer (Oxford, England : 1990), 1990, Volume: 26, Issue:6

    Topics: Antibiotics, Antineoplastic; Camptothecin; Cell Line; Cisplatin; DNA Topoisomerases, Type I; Drug Interactions; Etoposide; Female; Humans; Naphthoquinones; Novobiocin; Ovarian Neoplasms; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Tumor Cells, Cultured

1990
beta-hydroxyisovalerylshikonin inhibits the cell growth of various cancer cell lines and induces apoptosis in leukemia HL-60 cells through a mechanism different from those of Fas and etoposide.
    Journal of biochemistry, 1999, Volume: 125, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Calcium-Calmodulin-Dependent Protein Kinases; Caspase 3; Caspases; Cell Division; DNA Fragmentation; Drug Screening Assays, Antitumor; Enzyme Activation; Etoposide; fas Receptor; HL-60 Cells; Humans; Naphthoquinones; Nucleic Acid Synthesis Inhibitors; Signal Transduction; Tumor Cells, Cultured

1999
In vitro cytotoxicity of salvicine, a novel diterpenoid quinone.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1999, Volume: 20, Issue:4

    Topics: Antineoplastic Agents, Phytogenic; Cell Cycle; Etoposide; Female; HL-60 Cells; Humans; Interphase; K562 Cells; Naphthoquinones; Tumor Cells, Cultured; Vincristine

1999
Novel mechanism of cellular DNA topoisomerase II inhibition by the pyranonaphthoquinone derivatives alpha-lapachone and beta-lapachone.
    Cancer chemotherapy and pharmacology, 2001, Volume: 47, Issue:3

    Topics: Colony-Forming Units Assay; DNA Damage; Enzyme Activation; Enzyme Inhibitors; Etoposide; Naphthoquinones; Nucleic Acid Synthesis Inhibitors; Oxidative Stress; Topoisomerase II Inhibitors; Tumor Cells, Cultured

2001
DNA topoisomerase II as the primary cellular target for salvicine in Saccharomyces cerevisiae.
    Acta pharmacologica Sinica, 2001, Volume: 22, Issue:8

    Topics: Cytotoxicity, Immunologic; DNA Topoisomerases, Type II; Etoposide; Naphthoquinones; Saccharomyces cerevisiae

2001
Studies on fertilization in the teleost IV. Effects of aphidicolin and camptothecin on chromosome formation in fertilized medaka eggs.
    Development, growth & differentiation, 2002, Volume: 44, Issue:4

    Topics: Animals; Aphidicolin; Camptothecin; Chromosomes; DNA Polymerase I; DNA Topoisomerases; Etoposide; Fertilization; Meiosis; Mitogen-Activated Protein Kinases; Mitosis; Naphthoquinones; Oryzias; Protein Kinases; Topoisomerase Inhibitors; Zygote

2002
Cytotoxicity, apoptosis induction and downregulation of MDR-1 expression by the anti-topoisomerase II agent, salvicine, in multidrug-resistant tumor cells.
    International journal of cancer, 2003, Aug-10, Volume: 106, Issue:1

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Caspase 1; Caspase 3; Caspase 8; Caspase 9; Caspases; DNA, Complementary; Dose-Response Relationship, Drug; Down-Regulation; Doxorubicin; Drug Resistance, Neoplasm; Electrophoresis, Agar Gel; Etoposide; Flow Cytometry; Humans; Inhibitory Concentration 50; K562 Cells; Models, Chemical; Naphthoquinones; Proto-Oncogene Proteins c-bcl-2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Topoisomerase II Inhibitors; Tumor Cells, Cultured; Vincristine

2003
Cytotoxicity and DNA topoisomerase inhibitory activity of benz[f]indole-4,9-dione analogs.
    Bioscience, biotechnology, and biochemistry, 2003, Volume: 67, Issue:9

    Topics: Antineoplastic Agents; Cell Line, Tumor; DNA Topoisomerases; DNA, Kinetoplast; DNA, Superhelical; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Etoposide; Humans; Indoles; Inhibitory Concentration 50; Naphthoquinones; Nucleic Acid Conformation; Structure-Activity Relationship; Topoisomerase Inhibitors

2003
Involvement of tumor necrosis factor receptor-associated protein 1 (TRAP1) in apoptosis induced by beta-hydroxyisovalerylshikonin.
    The Journal of biological chemistry, 2004, Oct-08, Volume: 279, Issue:41

    Topics: Acetylcysteine; Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; Blotting, Northern; Blotting, Western; Cell Death; Cell Line; Cell Line, Tumor; Coloring Agents; Cytochromes c; Cytosol; DNA, Complementary; Dose-Response Relationship, Drug; Enzyme Inhibitors; Etoposide; Gene Expression Regulation; Genetic Vectors; HL-60 Cells; HSP90 Heat-Shock Proteins; Humans; K562 Cells; Mitochondria; Naphthoquinones; Oligonucleotide Array Sequence Analysis; Plasmids; Reactive Oxygen Species; RNA, Small Interfering; Subcellular Fractions; Time Factors; Transfection

2004
Drug-induced death of the asexual blood stages of Plasmodium falciparum occurs without typical signs of apoptosis.
    Microbes and infection, 2006, Volume: 8, Issue:6

    Topics: Animals; Antimalarials; Apoptosis; Atovaquone; Cells, Cultured; Chloroquine; DNA Fragmentation; DNA, Protozoan; Enzyme Inhibitors; Erythrocytes; Etoposide; Flow Cytometry; Humans; In Situ Nick-End Labeling; Malaria, Falciparum; Membrane Potentials; Mitochondrial Membranes; Naphthoquinones; Nitric Oxide Donors; Parasitemia; Penicillamine; Plasmodium falciparum

2006
Reactive oxygen species contribute to cell killing and P-glycoprotein downregulation by salvicine in multidrug resistant K562/A02 cells.
    Cancer biology & therapy, 2007, Volume: 6, Issue:11

    Topics: Acetylcysteine; Antineoplastic Agents; Ascorbic Acid; ATP Binding Cassette Transporter, Subfamily B, Member 1; DNA Breaks, Double-Stranded; Drug Resistance, Multiple; Etoposide; Glutathione; Humans; Hydrogen Peroxide; K562 Cells; Naphthoquinones; Reactive Oxygen Species

2007
Topoisomerase inhibitors as anti-arthritic agents.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2008, Volume: 57, Issue:3

    Topics: Animals; Antirheumatic Agents; Arthritis, Rheumatoid; Camptothecin; Cattle; Cell Proliferation; Cells, Cultured; Chick Embryo; Chondrocytes; Doxorubicin; Enzyme Inhibitors; Etoposide; Interleukin-1; Naphthoquinones; Neutrophils; Rabbits; Synovial Membrane; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Vitamin K 3

2008
Peptidyl prolyl isomerase, Pin1 is a potential target for enhancing the therapeutic efficacy of etoposide.
    Current cancer drug targets, 2011, Volume: 11, Issue:3

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Cell Cycle; Cell Proliferation; DNA Damage; Drug Synergism; Enzyme Inhibitors; Etoposide; Flow Cytometry; Humans; Lung Neoplasms; Micronucleus Tests; Naphthoquinones; NIMA-Interacting Peptidylprolyl Isomerase; Peptidylprolyl Isomerase; Tumor Cells, Cultured; Tumor Stem Cell Assay

2011
Synthesis and evaluation of mansonone F derivatives as topoisomerase inhibitors.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:8

    Topics: Adenocarcinoma; Adenocarcinoma of Lung; Antigens, Neoplasm; Antineoplastic Agents; Carcinoma; Cell Line, Tumor; Cell Survival; DNA; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; DNA-Binding Proteins; Drug Screening Assays, Antitumor; Etoposide; Humans; Inhibitory Concentration 50; Lung Neoplasms; Naphthoquinones; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Plasmids; Pyrans; Quinones; Sesquiterpenes; Structure-Activity Relationship; Telomerase; Topoisomerase Inhibitors

2011
Survivin family proteins as novel molecular determinants of doxorubicin resistance in organotypic human breast tumors.
    Breast cancer research : BCR, 2014, May-30, Volume: 16, Issue:3

    Topics: Alternative Splicing; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Breast Neoplasms; Camptothecin; Cell Line, Tumor; Cell Proliferation; Cell Survival; DNA Damage; Doxorubicin; Drug Resistance, Neoplasm; Etoposide; Female; High-Throughput Screening Assays; Humans; Imidazoles; Inhibitor of Apoptosis Proteins; MCF-7 Cells; Naphthoquinones; Paclitaxel; Receptor, ErbB-2; Survivin; Tumor Suppressor Protein p53

2014
Influence of survivin-targeted therapy on chemosensitivity in the treatment of acute myeloid leukemia.
    Cancer letters, 2015, Oct-01, Volume: 366, Issue:2

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Doxorubicin; Drug Synergism; Etoposide; HL-60 Cells; Humans; Imidazoles; Inhibitor of Apoptosis Proteins; Leukemia, Myeloid, Acute; Molecular Targeted Therapy; Naphthoquinones; Survivin

2015
YM155 enhances the cytotoxic activity of etoposide against canine osteosarcoma cells.
    The Journal of veterinary medical science, 2019, Aug-24, Volume: 81, Issue:8

    Topics: Animals; Antineoplastic Agents; Apoptosis; Bone Neoplasms; Cell Proliferation; Dog Diseases; Dogs; Drug Synergism; Etoposide; Humans; Imidazoles; Mice; Naphthoquinones; Osteosarcoma; Survivin; Xenograft Model Antitumor Assays

2019
Targeting abundant survivin expression in liposarcoma: subtype dependent therapy responses to YM155 treatment.
    Journal of cancer research and clinical oncology, 2022, Volume: 148, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Doxorubicin; Etoposide; Female; Follow-Up Studies; Gene Expression Regulation, Neoplastic; Humans; Imidazoles; Liposarcoma; Male; Middle Aged; Naphthoquinones; Prognosis; Retrospective Studies; Survival Rate; Survivin; Tumor Cells, Cultured

2022
Antitumor Effect of
    Molecules (Basel, Switzerland), 2022, Jun-29, Volume: 27, Issue:13

    Topics: Antineoplastic Agents; Boraginaceae; Carcinoma, Hepatocellular; DNA Topoisomerases, Type II; Etoposide; Humans; Leukemia, Myeloid, Acute; Liver Neoplasms; Naphthoquinones; Oils, Volatile; Reactive Oxygen Species; Topoisomerase II Inhibitors

2022
Biological Activity of Naphthoquinones Derivatives in the Search of Anticancer Lead Compounds.
    Toxins, 2023, 05-20, Volume: 15, Issue:5

    Topics: Antineoplastic Agents; Cell Line, Tumor; Etoposide; Female; HEK293 Cells; Humans; Naphthoquinones

2023